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Displaying drugs 801 - 825 of 1120 in total
Bupropion (also known as the brand name product Wellbutrin®) is a norepinephrine/dopamine-reuptake inhibitor (NDRI) used most commonly for the management of Major Depressive Disorder (MDD), Seasonal Affective Disorder (SAD), and as an aid for smoking cessation. Bupropion exerts its pharmacological effects by weakly inhibiting the enzymes involved in the uptake...
Approved
Matched Description: … commonly for the management of Major Depressive Disorder (MDD), Seasonal Affective Disorder (SAD), and ... effects by weakly inhibiting the enzymes involved in the uptake of the neurotransmitters norepinephrine and ... from the synaptic cleft, therefore prolonging their duration of action within the neuronal synapse and
Matched Mixtures name: … Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-Release …
Matched Categories: … bupropion and naltrexone ... bupropion and dextromethorphan ... Dopamine And Norepinephrine Reuptake Inhibitors ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … BUPROPION BETA 150 MG ... BUPROPION BETA 300 MG …
Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection. It is marketed under the trade name Baraclude (BMS). Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer claims that it is more efficacious than previous agents...
Approved
Investigational
Matched Description: … Food and Drug Administration (FDA) in March 2005. ... Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the ... manufacturer claims that it is more efficacious than previous agents used to treat hepatitis B (lamivudine and
Matched Categories: … Nucleosides and Nucleotides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
Matched Products: … ENTECAVIR BETA 1 MG ... ENTECAVIR BETA 0.5MG ... ENTECAVIR BETA 0.5 MG …
Experimental
Matched Name: … (2R,3S,5S)-2-(Hydroxymethyl)-5-[(2-sulfoethyl)carbamoyl]-3-pyrrolidiniumyl 2-acetamido-2-deoxy-4-O-sulfo-beta-D-glucopyranoside …
Investigational
Matched Synonyms: … Gdp-.beta.-l-fucose ... Guanosine 5'-diphospho-.beta.-l-fucose ... Guanosine 5'-pyrophosphate, .beta.-l-fucopyranosyl ester …
Cystinosis is a rare disease caused by mutations in the CTNS gene that encodes for cystinosin, a protein responsible for transporting cystine out of the cell lysosome. A defect in cystinosin function is followed by cystine accumulation throughout the body, especially the eyes and kidneys. Several preparations of cysteamine exist...
Approved
Investigational
Matched Synonyms: … beta-aminoethanethiol ... beta-Mercaptoethylamine …
Matched Description: … in cystinosin function is followed by cystine accumulation throughout the body, especially the eyes and ... preparations of cysteamine exist for the treatment of cystinosis manifestations, some in capsule form, and ... L15616] In particular, cystine deposits on the eye can cause significant discomfort throughout the day and
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids and Derivatives ... Sulfur Compounds …
Experimental
Investigational
Matched Synonyms: … 1-(2-deoxy-.beta.-d-ribofuranosyl)cytosine ... 4-amino-1-(2-deoxy-.beta.-d-erythro-pentofuranosyl)-2(1h)-pyrimidinone …
N4-Hydroxyctidine, or EIDD-1931, is a ribonucleoside analog which induces mutations in RNA virions.[A193008,A193011] N4-hydroxycytidine was first described in the literature in 1980 as a potent mutagen of bacteria and phage. It has shown antiviral activity against Venezuelan equine encephalitis virus, and the human coronavirus HCoV-NL63 in vitro. N4-hydroxycytodine has been...
Experimental
Matched Synonyms: … beta-D-N-4-Hydroxycytidine ... Beta-D-N4-hydroxycytidine …
Matched Description: … in mice and human airway epithelial cells. ... A193011] N4-hydroxycytidine was first described in the literature in 1980 as a potent mutagen of bacteria and ... [A193023] It has shown antiviral activity against Venezuelan equine encephalitis virus,[A193008] and
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Producing a broad-spectrum activity against several RNA and DNA viruses, Ribavirin is a synthetic guanosine nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. It is primarily indicated for use in treating hepatitis C and viral hemorrhagic fevers. HCV is a single-stranded RNA virus that is categorized...
Approved
Matched Synonyms: … 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide ... 1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide …
Matched Description: … The dual therapy was administered for 48 weeks in patients with genotype 1, 4, 5, and 6, and 24 weeks ... in patients with genotype 2 and 3 [A19626]. ... nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. …
Matched Mixtures name: … Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules) …
Matched Categories: … Nucleosides and Nucleotides ... Nucleic Acids, Nucleotides, and Nucleosides …
Investigational
Matched Synonyms: … L-asparagine, n-(1-.beta.-d-arabinofuranosyl-1,2-dihydro-2-oxo-4-pyrimidinyl)- ... N4-(1-.beta.-d-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin-4-yl)-l-asparagine …
Polaprezinc is a chelated form of zinc and L-carnosine. It is a zinc-related medicine approved for the first time in Japan, which has been clinically used to treat gastric ulcers [L1307, L1308]. It was determined that polaprezinc may be effective in pressure ulcer treatment . A study in 2013 showed...
Experimental
Matched Synonyms: … beta-Alanyl-L-histidinato zinc …
Matched Description: … Polaprezinc is a chelated form of zinc and L-carnosine. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.[L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. Sumatriptan was granted FDA approval on 28 December 1992.
Approved
Investigational
Matched Description: … Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches ... [L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available …
Matched Mixtures name: … Sumatriptan and Naproxen Sodium ... Sumatriptan Succinate and Naproxen Sodium ... Sumatriptan and Naproxen Sodium …
Matched Categories: … Sulfur Compounds ... Genito Urinary System and Sex Hormones ... sumatriptan and naproxen ... Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … SUMATRIPTAN BETA 50MG ... SUMATRIPTAN BETA 100MG …
Experimental
Matched Synonyms: … Ebert-Merz beta-acid …
Matched Categories: … Sulfur Acids ... Sulfur Compounds …
Propiolactone is a lactone compound with a four-membered ring. It is a colorless liquid with a pungent slightly sweet odor. Propiolactone is a disinfectant used for the sterilization of blood plasma, vaccines, tissue grafts, surgical instruments, and enzymes. It has been used against bacteria, fungi, and virus. It is currently...
Approved
Withdrawn
Matched Synonyms: … beta-Propiolactone …
Matched Description: … It has been used against bacteria, fungi, and virus. ... disinfectant used for the sterilization of blood plasma, vaccines, tissue grafts, surgical instruments, and
Isoquercitrin is under investigation in clinical trial NCT04622865 (Masitinib Combined With Isoquercetin and Best Supportive Care in Hospitalized Patients With Moderate and Severe COVID-19).
Investigational
Matched Synonyms: … Quercetin 3-(beta-D-glucofuranoside) …
Matched Description: … Best Supportive Care in Hospitalized Patients With Moderate and Severe COVID-19). ... Isoquercitrin is under investigation in clinical trial NCT04622865 (Masitinib Combined With Isoquercetin and
Experimental
Matched Synonyms: … L-beta-Phenyllactic acid ... alpha-hydroxy-beta-phenyl-propionic acid …
Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) that was first approved for use in the United States in 1993. It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures[A186277,A186143] - today it is also widely used to treat neuropathic...
Approved
Investigational
Matched Description: … It is structurally and functionally related to another GABA derivative, [pregabalin]. ... other anti-epileptics, such as a relatively benign adverse effect profile, wide therapeutic index, and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Gabapentin and Prodrugs …
Matched Products: … GABAPENTIN BETA 100MG ... GABAPENTIN BETA 300MG ... GABAPENTIN BETA 400MG …
Ambrisentan is an orally active selective type A endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension. It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ability and delay clinical worsening. In addition, it is approved in the...
Approved
Investigational
Matched Description: … Patients studied displayed symptoms and etiologies predominantly of WHO Functional Class II-III. ... ability and delay clinical worsening. ... It is approved in Europe, Canada and the United States for use as a single agent to improve exercise …
Matched Categories: … ambrisentan and tadalafil …
Matched Products: … AMBRISENTAN BETA 5 MG FTA ... AMBRISENTAN BETA 10 MG FTA …
Eplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative regulatory feedback of aldosterone on renin secretion. The resulting increased plasma renin activity and aldosterone circulating levels do not overcome the effects of...
Approved
Matched Description: … antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and ... The resulting increased plasma renin activity and aldosterone circulating levels do not overcome the ... mineralocorticoid receptors relative to its binding to recombinant human glucocorticoid, progesterone and
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … EPLERENON BETA 25 MG ... EPLERENON BETA 50 MG …
Experimental
Matched Name: … Beta-D-Glucopyranose Spirohydantoin …
Experimental
Matched Name: … 11-Deoxy-Beta-Rhodomycin …
Experimental
Matched Name: … beta-D-Galactopyranuronic acid …
Experimental
Matched Synonyms: … beta-1,4-galactotrioside …
Matched Name: … beta-(1->4)-galactotriose …
Experimental
Matched Name: … octyl beta-D-galactopyranoside …
Experimental
Matched Name: … ORTHONITROPHENYL-BETA-D-FUCOPYRANOSIDE …
Investigational
Matched Synonyms: … 6-amino-9-(2',3'-dideoxy-.beta.-d-glycero-pentofuranosyl)purine ... 9-(2,3-dideoxy-.beta.-d-glycero-pentofuranosyl)-9h-purin-6-amine …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Displaying drugs 801 - 825 of 1120 in total