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Displaying drugs 801 - 825 of 1045 in total

Axitinib

Axitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3). Through this mechanism of action, axitinib blocks angiogenesis, tumour growth and metastases. It is reported to exhibit potency that is 50-450 times higher than that of the first generation...
Approved
Investigational
Matched Description: … [L6676] Through this mechanism of action, axitinib blocks angiogenesis, tumour growth and metastases. ... [A179398] It is most commonly marketed under the name Inlyta® and is available in oral formulations. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Benzamides and benzamide derivatives …
Matched Products: … Inlyta Film-coated Tablets 1mg ... Inlyta Film-coated Tablets 5mg ... INLYTA 3 MG FİLM KAPLI TABLET, 28 ADET …

Paroxetine

Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others. It was approved by the FDA in the early 1990s and marketed by SmithKline...
Approved
Investigational
Matched Description: … stress disorder, and symptoms of menopause, among others. ... of serotonin reuptake and has little effect on other neurotransmitters. ... [T653] It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham. …
Matched Products: … PALUXON 20 MG FİLM TABLET, 14 ADET ... PALUXON 20 MG FİLM TABLET, 28 ADET ... PALUXON 40 MG FİLM TABLET, 14 ADET …

Tenofovir alafenamide

Tenofovir alafenamide is a novel tenofovir prodrug developed in order to improve renal safety when compared to the counterpart tenofovir disoproxil. Both of these prodrugs were first created to cover the polar phosphonic acid group on tenofovir by using a novel oxycarbonyloxymethyl linkers to improve the oral bioavailability and intestinal...
Approved
Matched Description: … group on tenofovir by using a novel oxycarbonyloxymethyl linkers to improve the oral bioavailability and ... alafenamide is indicated to treat chronic hepatitis B,[L6241] treat HIV-1,[L4388,L6277,L6280,L6283] and ... [L4388,L9010] Tenofovir alafenamide was developed by Gilead Sciences Inc and granted FDA approval …
Matched Mixtures name: … DESCOVY FILM COATED TABLET 200 MG/25 MG ... DESCOVY FILM COATED TABLET 200 MG/10 MG ... ODEFSEY FILM-COATED TABLET 200MG/25MG/25MG …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Tenofovir and prodrugs ... emtricitabine and tenofovir alafenamide ... emtricitabine, tenofovir alafenamide and rilpivirine ... emtricitabine, tenofovir alafenamide and bictegravir …
Matched Products: … VEMLIDY FILM COATED TABLET 25 MG ... VEMLİDY 25 MG FİLM KAPLI TABLET, 30 ADET ... VEMLİDY 25 MG FİLM KAPLI TABLET, 90 ADET …

Alpelisib

Alpelisib is a phosphatidylinositol 3-kinase (PI3K) inhibitor with potent antitumor activity. It works by selectively inhibiting class I PI3K p110α , which is the catalytic subunit of PI3K, a lipid kinase that plays a role in various biological processes, including proliferation, survival, differentiation, and metabolism. Alpelisib was designed to target...
Approved
Investigational
Matched Description: … children who require systemic therapy. ... Alpelisib is marketed under the trade name Piqray and is available as oral tablets. ... that plays a role in various biological processes, including proliferation, survival, differentiation, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Trezilent 50mg Film-Coated Tablets ... Trezilent 200mg Film-Coated Tablets ... Trezilent 150mg Film-Coated Tablets …

Ibrutinib

Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase. It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials. Ibrutinib was developed by Pharmacyclics Inc and was first approved by the FDA in...
Approved
Matched Description: … It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies ... [A32299] Ibrutinib was developed by Pharmacyclics Inc and was first approved by the FDA in November 2013 ... [L45894] Ibrutinib was approved by the EMA in October 2014 [L45884] and by Health Canada in November …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … IMBRUVICA FILM-COATED TABLETS 140MG ... IMBRUVICA FILM-COATED TABLETS 560MG ... IMBRUVICA FILM-COATED TABLETS 420MG …

Risperidone

Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder. It is one of the most widely used SGAs. Paliperidone, another commonly used SGA, is the primary active metabolite of risperidone (i.e. 9-hydroxyrisperidone). Schizophrenia and...
Approved
Investigational
Matched Description: … D2 and serotonergic 5-HT2A activity, resulting in overactivity of central mesolimbic pathways and mesocortical ... mental health conditions including schizophrenia and bipolar disorder. ... Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and …
Matched Products: … RISPERIDON - CT 0.5MG FILM ... RISPEFAR FILM-COATED TABLET 1MG ... RISPEFAR FILM-COATED TABLET 2MG …

Letermovir

Letermovir recieved approval from the FDA on November 8th, 2017 for use in prophylaxis of cytomegalovirus (CMV) infection in allogeneic hematopoietic stem cell transplant patients. It is the first of a new class of CMV anti-infectives called DNA terminase complex inhibitors. Letermovir has recieved both priority and orphan drug status...
Approved
Investigational
Matched Description: … [A31290] Letermovir has recieved both priority and orphan drug status from the FDA. …
Matched Products: … PREVYMIS 240MG FILM-COATED TABLET ... PREVYMIS 480MG FILM-COATED TABLET ... PREVYMIS FILM COATED TABLET 240MG …

Ribociclib

Ribociclib is a selective cyclin-dependent kinase inhibitor, a class of drugs that help slow the progression of cancer by inhibiting two proteins called cyclin-dependent kinase 4 and 6 (CDK4/6). These proteins, when over-activated, can enable cancer cells to grow and divide too quickly. Targeting CDK4/6 with enhanced precision may play...
Approved
Investigational
Matched Description: … that help slow the progression of cancer by inhibiting two proteins called cyclin-dependent kinase 4 and ... These proteins, when over-activated, can enable cancer cells to grow and divide too quickly. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … KISQALI FILM-COATED TABLET 200MG ... Kryxana 200mg Film-coated Tablets ... VALAMOR 200 MG FİLM KAPLI TABLET, 63 ADET …

Deferiprone

Deferiprone is an oral iron chelator used as a second line agent in thalassemia syndromes when iron overload from blood transfusions occurs. Thalassemias are a type of hereditary anaemia due a defect in the production of hemoglobin. As a result, erythropoiesis, the production of new red blood cells, is impaired....
Approved
Matched Products: … FERRIPROX FILM-COATED TABLET 500 mg ... Ferriprox 1000mg Film-Coated Tablet ... HİERO 500 MG FİLM KAPLI TABLET, 100 ADET …

Capmatinib

Capmatinib is a small molecule kinase inhibitor targeted against c-Met (a.k.a. hepatocyte growth factor receptor [HGFR]), a receptor tyrosine kinase that, in healthy humans, activates signaling cascades involved in organ regeneration and tissue repair. Aberrant c-Met activation - via mutations, amplification, and/or overexpression - is known to occur in many...
Approved
Investigational
Matched Description: … such as STAT3, PI3K/ATK, and RAS/MAPK. ... tyrosine kinase that, in healthy humans, activates signaling cascades involved in organ regeneration and ... [A199122] Aberrant c-Met activation - via mutations, amplification, and/or overexpression - is known …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … TABRECTA FILM-COATED TABLET 150mg ... Rahika 150mg Film-coated Tablet ... TABRECTA FILM-COATED TABLET 200mg …

Daclatasvir

Daclatasvir is a direct-acting antiviral agent against Hepatitis C Virus (HCV) used for the treatment of chronic HCV genotype 1 and 3 infection. It is marketed under the name DAKLINZA and is contained in daily oral tablets as the hydrochloride salt form . Hepatitis C is an infectious liver disease...
Approved
Investigational
Matched Description: … It is marketed under the name DAKLINZA and is contained in daily oral tablets as the hydrochloride salt ... Combination therapies that include daclatasir can be used for challenging-to-treat patients who have ... daclatasvir and [DB08934] therapy were 88% and 99%, respectively [FDA Label]. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... daclatasvir, asunaprevir and beclabuvir …
Matched Products: … DAKLINZA 30 MG FILM KAPLI TABLET ,FILM KAPLI TABLET, 28 ADET ... DAKLINZA 60 MG FILM KAPLI TABLET ,FILM KAPLI TABLET, 28 ADET ... Daclavir 60mg Film Coated Tablet …

Ornidazole

Ornidazole has been used in trials studying the prevention of Elective Colorectal Surgery.
Investigational
Matched Mixtures name: … ORNISASIN 500 MG/500 MG FILM TABLET, 10 ADET ... ORNISASIN 500 MG/500 MG FILM TABLET, 20 ADET ... ORCIPOL 500 MG/500 MG FILM TABLET, 10 ADET …
Matched Categories: … ofloxacin and ornidazole ... cefixime and ornidazole ... levofloxacin and ornidazole ... Genito Urinary System and Sex Hormones ... ciprofloxacin and ornidazole …
Matched Products: … BITAZOL 250 MG FILM TABLET, 20 ADET ... ORNITOP 250 MG FILM TABLET, 20 ADET ... ORNITOP 500 MG FILM TABLET, 10 ADET …

Bosutinib

Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine kinase inhibitor indicated for chronic myelogenous leukemia (CML), specifically Philadelphia chromosome-positive (Ph+) CML. Philadelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein.[A6902,A261796,A261801] The first BCR-ABL inhibitor,...
Approved
Matched Description: … Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine ... BCR-ABL inhibitors like bosutinib inhibit most resistance-conferring BCR-ABL mutations except V299L and ... obtained from the open-label, randomized, multicenter trial BFORE that showed a significant improvement in major …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … BOSULİF 500 MG FİLM KAPLI TABLET, 28 ADET ... BOSULİF 500 MG FİLM KAPLI TABLET, 30 ADET ... BOSULİF 100 MG FİLM KAPLI TABLET, 28 ADET …

Rilpivirine

Rilpivirine is non-nucleoside reverse transcriptase inhibitor (NNRTI) which is used for the treatment of HIV-1 infections in treatment-naive patients. It is a diarylpyrimidine derivative. The internal conformational flexibility of rilpivirine and the plasticity of it interacting binding site gives it a very high potency and reduces the chance of resistance...
Approved
Matched Description: … [A31331] Rilpivirine was developed by Tilbotec, Inc. and FDA approved on May 20, 2011. ... [A31329] The internal conformational flexibility of rilpivirine and the plasticity of it interacting ... binding site gives it a very high potency and reduces the chance of resistance compared to other NNRTI's …
Matched Mixtures name: … COMPLERA FILM-COATED TABLET 200MG/25MG/300MG ... ODEFSEY 200 MG/25 MG/25 MG FİLM KAPLI TABLET, 90 ADET ... ODEFSEY 200 MG/25 MG/25 MG FİLM KAPLI TABLET, 30 ADET …
Matched Categories: … dolutegravir and rilpivirine ... emtricitabine, tenofovir disoproxil and rilpivirine ... emtricitabine, tenofovir alafenamide and rilpivirine …
Matched Products: … Edurant 25mg film-coated tablet ... EDURANT FILM-COATED TABLET 25 MG ... EDURANT 25 MG FILM KAPLI TABLET, 30 ADET …

Methimazole

Methimazole is a thionamide antithyroid agent that inhibits the synthesis of thyroid hormones.[A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949 and is now commonly used in the management of hyperthyroidism, particularly in those for whom more aggressive options such as surgery or radioactive iodine therapy are inappropriate.[L8336,L8339]...
Approved
Matched Description: … [A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949[A184502] and is now ... [carbimazole], which is an antithyroid medication used in the United Kingdom and parts of the former ... thionamide used in North America, [propylthiouracil],[L8339] and is the active metabolite of the pro-drug …
Matched Categories: … Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … PERİZOL 20 MG FİLM TABLET, 100 ADET ... PERİZOL 20 MG FİLM TABLET, 30 ADET ... PERİZOL 20 MG FİLM TABLET, 50 ADET …

Lercanidipine

Lercanidipine is a calcium channel blocker of the dihydropyridine class. It is sold under various commercial names including Zanidip.
Approved
Investigational
Matched Mixtures name: … ZANITEK 10 MG/10MG FILM TABLET,90 ADET ... ZANITEK 10 MG/10MG FILM TABLET, 30 ADET ... ZANITEK 20 MG/10MG FILM TABLET, 30 ADET …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... valsartan and lercanidipine ... enalapril and lercanidipine ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers …
Matched Products: … ZANIDIP 10MG FILM COATED TABLETS ... Zanidip 20mg, film-coated tablet ... LERCADIP 10 MG FILM TABLET, 30 ADET …

Lipoic acid

A vitamin-like antioxidant.
Approved
Investigational
Nutraceutical
Matched Mixtures name: … PIONAL 15/500/300 MG FILM TABLET, 60 ADET ... PIONAL 15/500/300 MG FILM TABLET, 90 ADET ... PIONAL 15/850/300 MG FILM TABLET, 60 ADET …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Various Alimentary Tract and Metabolism Products …
Matched Products: … ALATAB 600 MG FİLM TABLET, 30 ADET ... ALFAZAN 600 MG FİLM TABLET, 30 ADET ... TIOPATI 600 MG FILM TABLET, 30 ADET …

Canagliflozin

Canagliflozin, also known as Invokana, is a sodium-glucose cotransporter 2 (SGLT2) inhibitor used in the management of type 2 diabetes mellitus along with lifestyle changes including diet and exercise [FDA label]. It was initially approved by the FDA in 2013 for the management of diabetes and later approved in 2018...
Approved
Matched Description: … inhibitor used in the management of type 2 diabetes mellitus along with lifestyle changes including diet and ... It was initially approved by the FDA in 2013 for the management of diabetes and later approved in 2018 …
Matched Mixtures name: … FILM-COATED TABLETS 50 MG / 1000 MG ... FILM-COATED TABLETS 50 MG / 500 MG ... FILM-COATED TABLETS 150 MG / 500 MG …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and canagliflozin …
Matched Products: … FILM-COATED TABLETS 100 MG ... FILM-COATED TABLETS 300 MG ... Invokana 300mg Film-Coated Tablets …

Gefitinib

Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa.
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Iressa 250mg Film-coated Tablet ... VEIASU FILM-COATED TABLETS 250 MG ... GEFTINAT FILM COATED TABLETS 250 MG …

Gabapentin

Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) that was first approved for use in the United States in 1993. It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures[A186277,A186143] - today it is also widely used to treat neuropathic...
Approved
Investigational
Matched Description: … It is structurally and functionally related to another GABA derivative, [pregabalin]. ... other anti-epileptics, such as a relatively benign adverse effect profile, wide therapeutic index, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Gabapentin and Prodrugs …
Matched Products: … GEMUDA 100 MG FILM TABLET , FILM TABLET, 20 ADET ... GEMUDA 300 MG FILM TABLET , FILM TABLET, 50 ADET ... GEMUDA 400 MG FILM TABLET , FILM TABLET, 50 ADET …

Lorlatinib

Lorlatinib is a third-generation ALK tyrosine kinase inhibitor (TKI) for patients with ALK-positive metastatic non-small cell lung cancer which was first approved by the US FDA in November of 2018. It was subsequently approved by the EMA in 2019 for the treatment of select patients with previously treated advanced ALK-positive...
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Lorviqua 100 mg Film-Coated Tablets ... LORVIQUA FILM-COATED TABLET 25MG ... LORVIQUA FILM-COATED TABLET 100MG …

Mycophenolate mofetil

Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified as a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH). This drug is an immunosuppressant combined with drugs such as Cyclosporine and corticosteroids to prevent organ rejection after hepatic, renal, and cardiac transplants. It is...
Approved
Investigational
Matched Description: … Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified ... to prevent organ rejection after hepatic, renal, and cardiac transplants. ... [A180805] This drug is an immunosuppressant combined with drugs such as [Cyclosporine] and corticosteroids …
Matched Categories: … Mycophenolic Acid and Prodrugs …
Matched Products: … MYFENAX FILM-COATED TABLETS 500MG ... TARBETAX 500 MG FILM TABLET, 150 ADET ... CELLCEPT (FILM-COATED TABLETS 500 MG) …

Nalmefene

Nalmefene, a 6-methylene analogue of naltrexone, is an opioid receptor antagonist. It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist at the kappa (κ)-opioid receptor. In Europe, nalmefene oral tablets are used to reduce alcohol consumption in adults with alcohol dependence. Nalmefene...
Approved
Investigational
Withdrawn
Matched Description: … [L40684] It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist …
Matched Products: … SELINCRO 18MG FILM KAPLI TABLET ,42 TABLET ... SELINCRO 18MG FILM KAPLI TABLET ,7 TABLET ... SELINCRO 18MG FILM KAPLI TABLET ,TABLET, 28 ADET …

Ponatinib

Ponatinib is a novel Bcr-Abl tyrosine kinase inhibitor that is especially effective against the T315I mutation for the treatment of chronic myeloid leukemia. FDA approved on December 14, 2012.
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … ICLUSIG FILM-COATED TABLET 45 MG ... ICLUSIG FILM-COATED TABLET 15 MG ... ICLUSIG 15 MG FILM-COATED TABLETS …

Calcium acetate

The chemical compound calcium acetate is the calcium salt of acetic acid. It has been commonly referred to as the acetate of lime. The anhydrous form is very hygroscopic, therefore the monohydrate is the common form.
Approved
Investigational
Matched Description: … The chemical compound calcium acetate is the calcium salt of acetic acid. …
Matched Mixtures name: … OSVAREN 435 MG/235 MG 180 FILM KAPLI TABLET …
Matched Categories: … Calcium Salts ... Alimentary Tract and Metabolism ... ascorbic acid (vit C) and calcium ... calcium acetate and magnesium carbonate ... Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Matched Products: … FOSFAT-EX 700 MG FILM TABLET,FILM TABLET, 100 ADET ... FIX-AT 475MG FILM KAPLI TABLET, 90 ADET ... FIX-AT 950 MG FILM KAPLI TABLET, 90 ADET …
Displaying drugs 801 - 825 of 1045 in total