Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Displaying drugs 801 - 825 of 1126 in total

Diamorphine

Diamorphine (heroin) is a narcotic analgesic that may be habit-forming. It is a controlled substance (opium derivative) listed in the U.S. Code of Federal Regulations, Title 21 Parts 329.1, 1308.11 (1987). Sale is forbidden in the United States by Federal statute. (Merck Index, 11th ed) Internationally, diamorphine is controlled under...
Approved
Illicit
Investigational
Matched Description: … As heroin, it is illegal to manufacture, possess, or sell in the United States and the UK. ... (Merck Index, 11th ed) Internationally, diamorphine is controlled under Schedules I and IV of the Single …
Matched Salts name: … Diamorphine hydrochloride …
Matched Products: … Diacetylmorphine Hydrochloride ... Diamorphine Hydrochloride Inj 30mg/ml BP ... Diamorphine Hydrochloride Inj 100mg/ml BP …

YT-001

Investigational
Matched Synonyms: … L-Threonine, N-(1-oxotetradecyl)-L-α-glutamyl-L-alanyl-L-valyl-L-seryl-L-leucyl-L-lysyl-L-prolyl- …

Lixisenatide

Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes mellitus (T2DM). It is sold by Sanofi-Aventis under the brand name Adlyxin in the US and Lyxumia in the EU. Adlyxin recieved FDA approval July 28, 2016.
Approved
Matched Synonyms: … des-38-proline-exendine-4 (Heloderma suspectum)-(1-39)-peptidylpenta-L-lysyl-L-lysinamide …
Matched Description: … It is sold by Sanofi-Aventis under the brand name Adlyxin in the US[L763] and Lyxumia in the EU. …
Matched Mixtures name: … LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL) ... LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL) …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin glargine and lixisenatide …

Itepekimab

Itepekimab is under investigation in clinical trial NCT03546907 (Proof-of-concept Study to Assess the Efficacy, Safety and Tolerability of SAR440340 (Anti-il-33 Mab) in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)).
Investigational
Matched Synonyms: … Immunoglobulin igg4 (230-proline), anti-(human interleukin 33) (human monoclonal regn3500 .gamma.4-chain …
Matched Description: … investigation in clinical trial NCT03546907 (Proof-of-concept Study to Assess the Efficacy, Safety and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Valopicitabine

The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus (HCV) activity. Upon administration, valopicitabine is converted into 2'-C-methylcytidine; upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus...
Experimental
Matched Synonyms: … 2'-C-methylcytidine 3'-O-L-valinyl ester …
Matched Description: … This blocks viral production of HCV RNA and thus viral replication. [from NCI] ... upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and ... The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

PR1 leukemia peptide vaccine

PR1 leukemia peptide vaccine is under investigation in clinical trial NCT00513578 (Vaccine Therapy and GM-CSF in Treating Patients With Low-Risk or Intermediate-Risk Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … L-VALINE, L-VALYL-L-LEUCYL-L-GLUTAMINYL-L-.ALPHA. …
Matched Description: … PR1 leukemia peptide vaccine is under investigation in clinical trial NCT00513578 (Vaccine Therapy and …

TERT-572

Investigational
Matched Synonyms: … L-arginyl-l-leucyl-l-phenylalanyl-l-phenylalanyl-l-tyrosyl-l-arginyl-l-lysyl-l-seryl-l-valine ... L-valine, l-arginyl-l-leucyl-l-phenylalanyl-l-phenylalanyl-l-tyrosyl-l-arginyl-l-lysyl-l-seryl- …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …

Venlafaxine

Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). Its active metabolite, desvenlafaxine, works by blocking the reuptake of serotonin and norepinephrine, which are key neurotransmitters in mood regulation. Venlafaxine is officially approved to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, and...
Approved
Matched Description: … Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). ... Its active metabolite, [desvenlafaxine], works by blocking the reuptake of serotonin and norepinephrine ... treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, and …
Matched Salts name: … Venlafaxine hydrochloride …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors …
Matched Products: … VALOSINE S.R. CAPSULES 75 MG ... Venlafaxine hydrochloride ... Venlafaxine Hydrochloride …

Aldesleukin

Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. This recombinant form differs from...
Approved
Matched Synonyms: … 125-L-serine-2-133-interleukin 2 (human reduced) …
Matched Description: … Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression ... codon for this amino acid was deleted during the genetic engineering procedure; c) the molecule has serine ... Aldesleukin is not glycosylated because it is derived from E. coli; b) the molecule has no N-terminal alanine …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …

Reltecimod

Reltecimod is under investigation in clinical trial NCT02469857 (Phase III Efficacy and Safety Study of AB103 in the Treatment of Patients With Necrotizing Soft Tissue Infections).
Investigational
Matched Synonyms: … D-alanyl-L-seryl-L-prolyl-L-methionyl-L-leucyl-L-valyl-L-alanyl-L-tyrosyl-L-aspartyl-D-alanine …
Matched Description: … Reltecimod is under investigation in clinical trial NCT02469857 (Phase III Efficacy and Safety Study …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Costimulatory and Inhibitory T-Cell Receptors …

Clomipramine

Clomipramine, the 3-chloro analog of imipramine, is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, clomipramine does not affect mood or arousal, but may cause sedation. In depressed individuals,...
Approved
Investigational
Vet approved
Matched Description: … TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... , are more potent inhibitors of serotonin reuptake than secondary amine TCAs, such as nortriptyline and …
Matched Salts name: … Clomipramine hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Clomipramine Hydrochloride ... clomiPRAMINE Hydrochloride ... Clomipramine hydrochloride …

Desmeninol

Experimental
Matched Synonyms: … Methionine hydroxy analog …
Matched Categories: … Amino Acids, Peptides, and Proteins …

gamma-Glutamyl[S-(2-iodobenzyl)cysteinyl]glycine

Experimental
Matched Name: … gamma-Glutamyl[S-(2-iodobenzyl)cysteinyl]glycine …

Phenoxybenzamine

An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Approved
Matched Description: … It has been used to treat hypertension and as a peripheral vasodilator. …
Matched Salts name: … Phenoxybenzamine hydrochloride …
Matched Products: … Phenoxybenzamine Hydrochloride ... Phenoxybenzamine hydrochloride …

MIV-711

Investigational
Matched Synonyms: … -4-yl]-4-methyl-1-oxopentan-2-yl]-4-[5-fluoro-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]benzamide hydrochloride …

Isoxsuprine

A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labor.
Approved
Withdrawn
Matched Description: … A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. ... It is used in the treatment of peripheral vascular disease and in premature labor. …
Matched Salts name: … Isoxsuprine hydrochloride …
Matched Products: … Isoxsuprine Hydrochloride ... ISOXSUPRINE HYDROCHLORIDE …

Nalpha-(2-Naphthylsulfonylglycyl)-3-Amidino-D,L-Phenylalanine-Isopropylester

Experimental
Matched Name: … Nalpha-(2-Naphthylsulfonylglycyl)-3-Amidino-D,L-Phenylalanine-Isopropylester …

Cycloserine

Antibiotic substance produced by Streptomyces garyphalus.
Approved
Matched Synonyms: … cyclo-D-Serine …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Cysteine

A thiol-containing non-essential amino acid that is oxidized to form cystine.
Approved
Nutraceutical
Matched Salts name: … Cysteine hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Cysteine Hydrochloride ... L-Cysteine Hydrochloride …

Ginisortamab

Ginisortamab is under investigation in clinical trial NCT04393298 (A Study to Assess the Safety, Pharmacokinetics and Anti Tumor Activity of UCB6114 Administered Intravenously to Participants With Advanced Solid Tumors).
Investigational
Matched Synonyms: … Immunoglobulin g4 (232-proline), anti-(human gremlin 1) (human monoclonal ucb6114 .gamma.4-chain), disulfide …
Matched Description: … is under investigation in clinical trial NCT04393298 (A Study to Assess the Safety, Pharmacokinetics and …

Epinastine

Epinastine is used for the prevention of itching associated with allergic conjunctivitis. It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and H2-receptors to...
Approved
Investigational
Matched Description: … binding to both the H1- and H2-receptors to stop itching and provide lasting protection, and 3. prevents ... stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine …
Matched Salts name: … Epinastine hydrochloride …
Matched Categories: … Decongestants and Antiallergics ... Histamine Agents ... Histamine Antagonists ... Histamine H1 Inhibitors ... Histamine H1 Antagonists …
Matched Products: … Epinastine Hydrochloride ... RELESTAT (EPINASTINE HYDROCHLORIDE OPHTHALMIC SOLUTION 0.5 MG/ML) ... RELESTAT (EPINASTINE HYDROCHLORIDE OPTHALMIC SOLUTION) 0.5mg/ml …

Sabatolimab

Sabatolimab is under investigation in clinical trial NCT03946670 (A Study of MBG453 in Combination With Hypomethylating Agents in Subjects With IPSS-R Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS).).
Investigational
Matched Synonyms: … Immunoglobulin g4 (226-proline,de-c-terminal-lysine), anti-(human hepatitis virus a cellular receptor …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

Butenafine

Butenafine hydrochloride is a synthetic benzylamine antifungal agent. Butenafine's mechanism of action is believed to involve the synthesis inhibition of sterols. In particular, butenafine acts to inhibit the activity of the squalene epoxidase enzyme that is essential in the formation of sterols necessary for fungal cell membranes.
Approved
Matched Description: … Butenafine hydrochloride is a synthetic benzylamine antifungal agent. …
Matched Salts name: … Butenafine hydrochloride …
Matched Products: … Butenafine Hydrochloride 1% ... Butenafine Hydrochloride ... Butenafine Hydrochloride Jock Itch …

Leupeptin

Investigational
Matched Synonyms: … Acetyl-leucyl-leucyl-argininal ... Acetyl-l-leucyl-l-leucyl-l-argininal …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Piperaquine

Piperaquine is an antimalarial agent first synthesized in the 1960's and used throughout China . Its use declined in the 1980's as piperaquine resistant strains of Plasmodium falciparum appeared and artemisinin derivatives became available. It has come back into use in combination with the artemisinin derivative DB11638 as part of...
Approved
Experimental
Investigational
Matched Synonyms: … 1,3-bis[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propane …
Matched Description: … Piperaquine is an antimalarial agent first synthesized in the 1960's and used throughout China [A31550 ... Its use declined in the 1980's as piperaquine resistant strains of *Plasmodium falciparum* appeared and …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... artenimol and piperaquine ... arterolane and piperaquine ... artemisinin and piperaquine …
Displaying drugs 801 - 825 of 1126 in total