Displaying drugs 8226 - 8250 of 9497 in total
Phenaridine
Phenaridine (2,5-Dimethylfentanyl) is a synthetic fentanyl derivative opioid. It was developed in 1972, and is used for surgical anasthesia in Russia. Phenaridine has similar effects to fentanyl. In rat studies, it was less potent than fentanyl. Side effects include itching, nausea and serious to life threatening respiratory depression. Fentanyl analogs...
Illicit
Matched Iupac: … N-[2,5-dimethyl-1-(2-phenylethyl)piperidin-4-yl]-N-phenylpropanamide …
Decoquinate
Decoquinate is used in veterinary to delay the growth and reproduction of coccidian parasites.
Experimental
Vet approved
Matched Iupac: … ethyl 6-(decyloxy)-7-ethoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate …
Psilocybin
Psilocybin has been investigated for the treatment of Anxiety and Stage IV Melanoma. In November, 2019, it was granted Breakthrough Therapy status by the FDA.
Investigational
Matched Iupac: … ({3-[2-(dimethylamino)ethyl]-1H-indol-4-yl}oxy)phosphonic acid …
ORG-25435
Org 25435 has been used in trials studying the treatment of Anaesthesia.
Investigational
Matched Iupac: … 2,6-dimethoxy-4-methylphenyl (2R)-2-[bis(2-methoxyethyl)amino]butanoate …
Oltipraz
Oltipraz has been used in trials studying the treatment and prevention of Lung Cancer, Liver Fibrosis, Liver Cirrhosis, and Non-alcoholic Fatty Liver Disease.
Investigational
Matched Iupac: … 4-methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione …
Sivelestat
Sivelestat has been used in trials studying the treatment of Acute Lung Injury and Respiratory Distress Syndrome, Adult.
Investigational
Matched Iupac: … 2-[(2-{4-[(2,2-dimethylpropanoyl)oxy]benzenesulfonamido}phenyl)formamido]acetic acid …
Tiropramide
Tiropramide is under investigation in clinical trial NCT01629212 (Comparison of the Efficacy and Safety of Tiropramide and Octylonium in the Treatment of Irritable Bowel Syndrome).
Investigational
Matched Iupac: … 3-{4-[2-(diethylamino)ethoxy]phenyl}-2-(phenylformamido)-N,N-dipropylpropanamide …
Flurbiprofen axetil
Flurbiprofen axetil is under investigation in clinical trial NCT02043366 (Effect of Butorphanol Combined With Flurbiprofen Axetil on Preventing Hyperalgesia Induced by Remifentanil in Patients).
Investigational
Matched Iupac: … 1-(acetyloxy)ethyl 2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoate …
Haletazole
Experimental
Matched Iupac: … {2-[4-(5-chloro-1,3-benzothiazol-2-yl)phenoxy]ethyl}diethylamine …
Matched Salts cas: … 10390-80-4 …
Matched Salts cas: … 10390-80-4 …
Gold sodium thiosulfate
Experimental
Matched Iupac: … trisodium 1,5-dioxa-2lambda6,3,6lambda6,7-tetrathia-4-auraspiro[3.3]heptane-2,2,6,6-tetrone …
Rovatirelin
Rovatirelin is under investigation in clinical trial NCT01384435 (A Phase II Double Blind Comparative Study of KPS-0373 in Patients With Spinocerebellar Degeneration (SCD)).
Investigational
Matched Iupac: … -1,3-oxazolidine-4-carboxamide ... (4S,5S)-5-methyl-N-[(2S)-1-[(2R)-2-methylpyrrolidin-1-yl]-1-oxo-3-(1,3-thiazol-4-yl)propan-2-yl]-2-oxo …
Glesatinib
Investigational
Matched Iupac: … )-1-[2-(4-fluorophenyl)acetyl]thiourea ... 3-(3-fluoro-4-{[2-(5-{[(2-methoxyethyl)amino]methyl}pyridin-2-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl …
Tezosentan
Tezosentan is an intravenous endothelin receptor A/B antagonist. Tezosentan was initially developed for vasodilation in patients with acute heart failure but studies have shown that it does not assist in the treatment of dyspnea or prevent cardiovascular events.
Investigational
Matched Iupac: … N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-1,2,3,4-tetrazol-5-yl)pyridin-4-yl]pyrimidin-4-yl …
TMC-649128
TMC-649128 is under investigation in clinical trial NCT01391117 (TMC649128HPC1002 - a Trial inGenotype 1 Hepatitis C Virus (HCV) - Infected Participants to Determine the Safety, Tolerability, Pharmacokinetics and Antiviral Activity of TMC649128, Alone and Combined With Pegylated Interferon + Ribavirin).
Investigational
Matched Iupac: … [(2R,3S,4S,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-2-azido-4-methyl-3-[(2-methylpropanoyl)oxy …
GLPG-0259
GLPG-0259 is under investigation in clinical trial NCT01024517 (GLPG0259 Solid Formulation Bioavailability and Food Effect).
Investigational
Matched Iupac: … 4-[8-({4-[(1S,4S)-5-(propan-2-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]phenyl}amino)-[1,2,4]triazolo[1,5 …
PF-06882961
PF-06882961 is under investigation in clinical trial NCT03985293 (A 16 Week Study to Evaluate the Efficacy and Safety of PF-06882961 in Adults With Type 2 Diabetes Mellitus).
Investigational
Matched Iupac: … 2-[(4-{6-[(4-cyano-2-fluorophenyl)methoxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-{[(2S)-oxetan-2-yl]methyl …
Deacetoxyvinzolidine
Experimental
Matched Iupac: … ,6',13'-tetraen-4'-yl]-17-ethyl-17-hydroxy-1,11-diazatetracyclo[13.3.1.0^{4,12}.0^{5,10}]nonadeca-4(12 ... methyl (13S,15R,17S)-13-[(1'R,2R,9'R,12'R,19'S)-4-(2-chloroethyl)-12'-ethyl-5'-methoxy-8'-methyl-3,5- ... -8',16'-diazaspiro[1,4-oxazolidine-2,10'-pentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadecane]-2',4' …
Acyline
Acyline has been investigated for the prevention and treatment of Hypogonadism and Contraception.
Investigational
Matched Iupac: … acetamidophenyl)propanamido]-3-(4-acetamidophenyl)propanamido]-4-methylpentanamide ... pyrrolidin-1-yl]-1-oxo-6-[(propan-2-yl)amino]hexan-2-yl]-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2R)-2-[(2R)-3-(4- ... acetamido-3-(naphthalen-2-yl)propanamido]propanamido]-3-(pyridin-3-yl)propanamido]-3-hydroxypropanamido]-3-(4- …
Succinyl-Coenzyme A
Experimental
Matched Iupac: … 4-[(2-{3-[(2R)-3-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl ... phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-2-hydroxy-3-methylbutanamido]propanamido}ethyl)sulfanyl]-4- …
Sulbutiamine
Sulbutiamine is a synthetic derivative of thiamine (vitamin B1) under the market name Arcalion that is composed of two modified thiamine molecules to form a dimer. It is highly lipophilic, allowing it to cross the blood-brain barrier more easily than other thiamine derivatives. Although its clinical efficacy is not yet...
Experimental
Matched Iupac: … (3E)-4-{N-[(4-amino-2-methylpyrimidin-5-yl)methyl]formamido}-3-{[(2E)-2-{N-[(4-amino-2-methylpyrimidin …
5-ALPHA-PREGNANE-3-BETA-OL-HEMISUCCINATE
Experimental
Matched Iupac: … -7-yl]oxy}-4-oxobutanoic acid ... 4-{[(1S,3aS,3bR,5aS,7S,9aS,9bS,11aS)-1-acetyl-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren …
Emicerfont
Emicerfont has been used in trials studying the diagnostic and treatment of Social Anxiety Disorder and Irritable Bowel Syndrome (IBS).
Investigational
Matched Iupac: … 1-{1-[1-(4-methoxy-2-methylphenyl)-6-methyl-1H,2H,3H-pyrrolo[2,3-b]pyridin-4-yl]-1H-pyrazol-3-yl}imidazolidin …
Fonadelpar
Fonadelpar is under investigation in clinical trial NCT03527212 (A Study to Assess the Safety and Effectiveness of SJP-0035 for the Treatment of Patients With Dry Eye Disease).
Investigational
Matched Iupac: … 2-[(5-methyl-3-{2-[4-(propan-2-yl)-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]ethyl}-1,2-benzoxazol …
Fepixnebart
Fepixnebart is under investigation in clinical trial NCT04456686 (Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Osteoarthritis).
Investigational
Displaying drugs 8226 - 8250 of 9497 in total