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Displaying drugs 8351 - 8375 of 9550 in total
Ciluprevir
The compound, named BILN 2061, is an orally active inhibitor of the HCV NS3 protease and the first member of this new drug class to be tested in humans.
Investigational
Matched Iupac: … -thiazol-4-yl}quinolin-4-yl)oxy]-2,15-dioxo-3,16-diazatricyclo[14.3.0.0^{4,6}]nonadec-7-ene-4-carboxylic ... (1S,4R,6S,7Z,14S,18R)-14-{[(cyclopentyloxy)carbonyl]amino}-18-[(7-methoxy-2-{2-[(propan-2-yl)amino]-1,3 …
Zoliflodacin
Zoliflodacin has been used in trials studying the basic science and treatment of Gonorrhoea.
Investigational
Matched Iupac: … (4'R,6'S,7'S)-17'-fluoro-4',6'-dimethyl-13'-[(4S)-4-methyl-2-oxo-1,3-oxazolidin-3-yl]-5',15'-dioxa-2' …
Acetyldihydrocodeine
Experimental
Illicit
Matched Iupac: … -7(18),8,10-trien-14-yl acetate ... (1S,5R,13R,14S,17R)-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca …
Glesatinib
Investigational
Matched Iupac: … 3-(3-fluoro-4-{[2-(5-{[(2-methoxyethyl)amino]methyl}pyridin-2-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl ... )-1-[2-(4-fluorophenyl)acetyl]thiourea …
Tezosentan
Tezosentan is an intravenous endothelin receptor A/B antagonist. Tezosentan was initially developed for vasodilation in patients with acute heart failure but studies have shown that it does not assist in the treatment of dyspnea or prevent cardiovascular events.
Investigational
Matched Iupac: … N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-1,2,3,4-tetrazol-5-yl)pyridin-4-yl]pyrimidin-4-yl ... ]-5-(propan-2-yl)pyridine-2-sulfonamide …
TMC-649128
TMC-649128 is under investigation in clinical trial NCT01391117 (TMC649128HPC1002 - a Trial inGenotype 1 Hepatitis C Virus (HCV) - Infected Participants to Determine the Safety, Tolerability, Pharmacokinetics and Antiviral Activity of TMC649128, Alone and Combined With Pegylated Interferon + Ribavirin).
Investigational
Matched Iupac: … [(2R,3S,4S,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-2-azido-4-methyl-3-[(2-methylpropanoyl)oxy …
GLPG-0259
GLPG-0259 is under investigation in clinical trial NCT01024517 (GLPG0259 Solid Formulation Bioavailability and Food Effect).
Investigational
Matched Iupac: … 4-[8-({4-[(1S,4S)-5-(propan-2-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]phenyl}amino)-[1,2,4]triazolo[1,5 ... -a]pyrazin-5-yl]furan-2-carboxamide …
PF-06882961
PF-06882961 is under investigation in clinical trial NCT03985293 (A 16 Week Study to Evaluate the Efficacy and Safety of PF-06882961 in Adults With Type 2 Diabetes Mellitus).
Investigational
Matched Iupac: … 2-[(4-{6-[(4-cyano-2-fluorophenyl)methoxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-{[(2S)-oxetan-2-yl]methyl …
Beta-hydroxyfentanyl
Experimental
Illicit
Matched Iupac: … N-[1-(2-hydroxy-2-phenylethyl)piperidin-4-yl]-N-phenylpropanamide …
Biopterin
A natural product that has been considered as a growth factor for some insects. [PubChem]
Experimental
Matched Iupac: … 2-amino-6-[(1S,2R)-1,2-dihydroxypropyl]-3,4-dihydropteridin-4-one …
Octylphenoxy polyethoxyethanol
Experimental
Matched Iupac: … 89-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78,81,84,87 …
Levopropoxyphene
Levopropoxyphene is a stereoisomer of propoxyphene in the form of 2S, 3R enantiomer. It was sold as an antitussive, but it was removed from the market in the 70s. Levopropoxyphene was developed by Lilly and FDA approved on March 21st, 1962. This drug presented different dosages and it was administered...
Withdrawn
Matched Iupac: … (2R,3S)-4-(dimethylamino)-3-methyl-1,2-diphenylbutan-2-yl propanoate …
CYCLOHEXYL-NORSTATINE
Experimental
Matched Iupac: … propan-2-yl (2R,3S)-3-amino-4-cyclohexyl-2-hydroxybutanoate …
Decoquinate
Decoquinate is used in veterinary to delay the growth and reproduction of coccidian parasites.
Experimental
Vet approved
Matched Iupac: … ethyl 6-(decyloxy)-7-ethoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate …
Psilocybin
Psilocybin has been investigated for the treatment of Anxiety and Stage IV Melanoma. In November, 2019, it was granted Breakthrough Therapy status by the FDA.
Investigational
Matched Iupac: … ({3-[2-(dimethylamino)ethyl]-1H-indol-4-yl}oxy)phosphonic acid …
ORG-25435
Org 25435 has been used in trials studying the treatment of Anaesthesia.
Investigational
Matched Iupac: … 2,6-dimethoxy-4-methylphenyl (2R)-2-[bis(2-methoxyethyl)amino]butanoate …
Oltipraz
Oltipraz has been used in trials studying the treatment and prevention of Lung Cancer, Liver Fibrosis, Liver Cirrhosis, and Non-alcoholic Fatty Liver Disease.
Investigational
Matched Iupac: … 4-methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione …
Sivelestat
Sivelestat has been used in trials studying the treatment of Acute Lung Injury and Respiratory Distress Syndrome, Adult.
Investigational
Matched Iupac: … 2-[(2-{4-[(2,2-dimethylpropanoyl)oxy]benzenesulfonamido}phenyl)formamido]acetic acid …
Tiropramide
Tiropramide is under investigation in clinical trial NCT01629212 (Comparison of the Efficacy and Safety of Tiropramide and Octylonium in the Treatment of Irritable Bowel Syndrome).
Investigational
Matched Iupac: … 3-{4-[2-(diethylamino)ethoxy]phenyl}-2-(phenylformamido)-N,N-dipropylpropanamide …
Flurbiprofen axetil
Flurbiprofen axetil is under investigation in clinical trial NCT02043366 (Effect of Butorphanol Combined With Flurbiprofen Axetil on Preventing Hyperalgesia Induced by Remifentanil in Patients).
Investigational
Matched Iupac: … 1-(acetyloxy)ethyl 2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoate …
Haletazole
Experimental
Matched Iupac: … {2-[4-(5-chloro-1,3-benzothiazol-2-yl)phenoxy]ethyl}diethylamine …
Matched Salts cas: … 10390-80-4 …
Matched Salts cas: … 10390-80-4 …
Gold sodium thiosulfate
Experimental
Matched Iupac: … trisodium 1,5-dioxa-2lambda6,3,6lambda6,7-tetrathia-4-auraspiro[3.3]heptane-2,2,6,6-tetrone …
Deacetoxyvinzolidine
Experimental
Matched Iupac: … methyl (13S,15R,17S)-13-[(1'R,2R,9'R,12'R,19'S)-4-(2-chloroethyl)-12'-ethyl-5'-methoxy-8'-methyl-3,5- ... ,6',13'-tetraen-4'-yl]-17-ethyl-17-hydroxy-1,11-diazatetracyclo[13.3.1.0^{4,12}.0^{5,10}]nonadeca-4(12 ... -8',16'-diazaspiro[1,4-oxazolidine-2,10'-pentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadecane]-2',4' …
Acyline
Acyline has been investigated for the prevention and treatment of Hypogonadism and Contraception.
Investigational
Matched Iupac: … acetamidophenyl)propanamido]-3-(4-acetamidophenyl)propanamido]-4-methylpentanamide ... pyrrolidin-1-yl]-1-oxo-6-[(propan-2-yl)amino]hexan-2-yl]-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2R)-2-[(2R)-3-(4- ... acetamido-3-(naphthalen-2-yl)propanamido]propanamido]-3-(pyridin-3-yl)propanamido]-3-hydroxypropanamido]-3-(4- …
C-peptide
C-peptide is under investigation in clinical trial NCT00278980 (Effect of C-peptide on Diabetic Peripheral Neuropathy).
Investigational
Matched Iupac: … ]propanamido]-4-carboxybutanamido]-3-carboxypropanamido]-4-methylpentanamido]-4-carbamoylbutanamido]- ... (4S)-4-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carboxybutanamido ... 3-methylbutanamido]acetamido}-4-carbamoylbutanamido]-3-methylbutanamido]-4-{[(1S)-1-[({[({2-[(2S)-2-[ ... ({[(1S)-1-[({[(1S)-1-{[(1S)-1-{[(2S)-4-carbamoyl-1-[(2S)-2-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S …
Displaying drugs 8351 - 8375 of 9550 in total