Displaying drugs 8451 - 8475 of 12915 in total
Uracil C-13
Uracil C-13 is under investigation in clinical trial NCT01677338 (Phase 2 Study to Evaluate the Preliminary Performance of the C13-URA Breath Test Kit in Dyspeptic Subjects).
Investigational
Prizloncabtagene autoleucel
C-CAR039 is an autologous Chimeric Antigen Receptors (CAR) T-cell therapy expressing CD19/CD20 bi-specific CAR.
Investigational
Matched Synonyms: … self-inactivating, non-replicating lentiviral vector, encoding a bispecific chimeric antigen receptor ... autologous T lymphocytes obtained from peripheral blood lymphocytes by leukapheresis, transduced with a …
Garadacimab
Garadacimab is under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy and Safety of CSL312 on Catheter-associated Blood Clot Formation in Subjects With Cancer Who Receive Chemotherapy Through a PICC Line).
Investigational
Matched Description: … Garadacimab is under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy ... on Catheter-associated Blood Clot Formation in Subjects With Cancer Who Receive Chemotherapy Through a …
HCV-086
HCV-086 is a small molecule antiviral designed to block an enzyme required for the replication of the hepatitis C virus.
Investigational
Matched Iupac: … 2-(4-fluorophenyl)-6-methanesulfonamido-N-methyl-5-(propan-2-yloxy)-1-benzofuran-3-carboxamide …
Matched Description: … HCV-086 is a small molecule antiviral designed to block an enzyme required for the replication of the …
Matched Description: … HCV-086 is a small molecule antiviral designed to block an enzyme required for the replication of the …
Renzapride
Renzapride is currently in Phase III clinical development in the United States for the treatment of constipation-predominant irritable bowel syndrome (IBS-C). It has been suggested that renzapride is effective in the treatment of irritable bowel syndrome with alternating stool pattern. It is being developed by Alizyme of the UK.
Investigational
Matched Iupac: … 4-amino-N-{1-azabicyclo[3.3.1]nonan-4-yl}-3-chloro-2-methoxybenzamide …
N-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}-5-methyl-D-tryptophan
Experimental
Matched Name: … N-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}-5-methyl-D-tryptophan …
Matched Iupac: … (2R)-2-[4-(but-2-yn-1-yloxy)benzenesulfonamido]-3-(5-methyl-1H-indol-3-yl)propanoic acid …
Matched Iupac: … (2R)-2-[4-(but-2-yn-1-yloxy)benzenesulfonamido]-3-(5-methyl-1H-indol-3-yl)propanoic acid …
S-(2-oxo)pentadecylcoa
Experimental
Matched Iupac: … ]oxy}methyl)oxolan-3-yl]oxy}phosphonic acid ... {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3S)-3-hydroxy-2,2-dimethyl ... -3-{[2-({2-[(2-oxopentadecyl)sulfanyl]ethyl}carbamoyl)ethyl]carbamoyl}propoxy]phosphoryl}oxy)phosphoryl …
Immucillin-G
Experimental
Matched Synonyms: … (1S)-1,4-dideoxy-1,4-imino-1-(9-deazaguanin-9-yl)-D-ribitol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
2-{[4-(2-Acetylamino-2-pentylcarbamoyl-ethyl)-naphthalen-1-YL]-oxalyl-amino}-benzoic acid
Experimental
Matched Name: … 2-{[4-(2-Acetylamino-2-pentylcarbamoyl-ethyl)-naphthalen-1-YL]-oxalyl-amino}-benzoic acid …
Matched Iupac: … 2-(1-carboxy-N-{4-[(2S)-2-acetamido-2-(pentylcarbamoyl)ethyl]naphthalen-1-yl}formamido)benzoic acid …
Matched Iupac: … 2-(1-carboxy-N-{4-[(2S)-2-acetamido-2-(pentylcarbamoyl)ethyl]naphthalen-1-yl}formamido)benzoic acid …
Trencam-3,2-Hopo
Experimental
GED-0507-34-Levo
GED-0507-34-Levo is under investigation in clinical trial NCT02808390 (Efficacy and Safety Study of Ged-0507-34-levo for Treatment of UC).
Investigational
Matched Iupac: … (2S)-3-(4-aminophenyl)-2-methoxypropanoic acid …
Tipapkinogene sovacivec
Investigational
Malacidin A
Malacidin A, along with DB14052, is a member of a class of chemicals made by bacteria found in soil that can kill Gram-positive bacteria . Malacidins are 10-member macrocycle lipopeptides discovered via gene sequencing and bioinformatic analysis. While structurally similar to other macrocycle drugs like DB00080 and DB06087, Malacidin A...
Experimental
Matched Name: … Malacidin A …
Matched Iupac: … (3S)-3-{[(4S,7R,10S,13S,16S,22R,25S,29R,30aS)-10-(4-aminobutyl)-13-[carboxy(hydroxy)methyl]-22-(1-carboxyethyl ... -triacontahydropyrrolo[2,1-c]1,4,7,10,13,16,19,22,25-nonaazacyclooctacosan-4-yl]carbamoyl}-2-methyl-3- …
Matched Description: … Malacidin A, along with [DB14052], is a member of a class of chemicals made by bacteria found in soil ... While structurally similar to other macrocycle drugs like [DB00080] and [DB06087], Malacidin A appears …
Matched Iupac: … (3S)-3-{[(4S,7R,10S,13S,16S,22R,25S,29R,30aS)-10-(4-aminobutyl)-13-[carboxy(hydroxy)methyl]-22-(1-carboxyethyl ... -triacontahydropyrrolo[2,1-c]1,4,7,10,13,16,19,22,25-nonaazacyclooctacosan-4-yl]carbamoyl}-2-methyl-3- …
Matched Description: … Malacidin A, along with [DB14052], is a member of a class of chemicals made by bacteria found in soil ... While structurally similar to other macrocycle drugs like [DB00080] and [DB06087], Malacidin A appears …
Malacidin B
Malacidin B, along with DB14051, is a member of a class of chemicals made by bacteria found in soil that can kill Gram-positive bacteria . Malacidins are 10-member macrocycle lipopeptides discovered via gene sequencing and bioinformatic analysis. While structurally similar to other macrocycle drugs like DB00080 and DB06087, Malacidin B...
Experimental
Matched Iupac: … (3S)-3-{[(4S,7R,10S,13S,16S,22R,25S,29R,30aS)-10-(4-aminobutyl)-13-[carboxy(hydroxy)methyl]-22-(1-carboxyethyl ... -triacontahydropyrrolo[2,1-c]1,4,7,10,13,16,19,22,25-nonaazacyclooctacosan-4-yl]carbamoyl}-2-methyl-3- …
Matched Description: … Malacidin B, along with [DB14051], is a member of a class of chemicals made by bacteria found in soil …
Matched Description: … Malacidin B, along with [DB14051], is a member of a class of chemicals made by bacteria found in soil …
LY-2183240
LY-2183240 is an inhibitor of endocannabinoid reuptake/breakdown.
Investigational
Matched Synonyms: … 5-(biphenyl-4-ylmethyl)-n,n-dimethyl-1h-tetrazole-1-carboxamide ... 1h-tetrazole-1-carboxamide, 5-((1,1'-biphenyl)-4-ylmethyl)-n,n-dimethyl- …
Matched Iupac: … 5-({[1,1'-biphenyl]-4-yl}methyl)-N,N-dimethyl-1H-1,2,3,4-tetrazole-1-carboxamide …
Matched Iupac: … 5-({[1,1'-biphenyl]-4-yl}methyl)-N,N-dimethyl-1H-1,2,3,4-tetrazole-1-carboxamide …
Toyocamycin
4-Amino-5-cyano-7-(D-ribofuranosyl)-7H- pyrrolo(2,3-d)pyrimidine. Antibiotic antimetabolite isolated from Streptomyces toyocaensis cultures. It is an analog of adenosine, blocks RNA synthesis and ribosome function, and is used mainly as a tool in biochemistry.
Experimental
Matched Description: … It is an analog of adenosine, blocks RNA synthesis and ribosome function, and is used mainly as a tool …
N-[(1R)-1-(4-Bromophenyl)ethyl]-5-fluoro-2-hydroxybenzamide
Experimental
Matched Name: … N-[(1R)-1-(4-Bromophenyl)ethyl]-5-fluoro-2-hydroxybenzamide …
Matched Iupac: … N-[(1R)-1-(4-bromophenyl)ethyl]-5-fluoro-2-hydroxybenzamide …
Matched Iupac: … N-[(1R)-1-(4-bromophenyl)ethyl]-5-fluoro-2-hydroxybenzamide …
2,2-Dimethylbutyrate
Investigational
ABBV-011
ABBV-011 is an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting seizure-related 6 homolog conjugated to N-acetyl-gamma-calicheamicin.
Investigational
Netakimab
Netakimab is under investigation in clinical trial NCT03447704 (International Multicenter Comparative Randomized Placebo-controlled Clinical Study of Efficacy and Safety of BCD-085 in Patients With Ankylosing Spondylitis).
Investigational
Pemlimogene merolisbac
Pemlimogene merolisbac is under investigation in clinical trial NCT03371381 (An Efficacy and Safety Study of JNJ-64041757, a Live Attenuated Listeria Monocytogenes Immunotherapy, in Combination With Nivolumab Versus Nivolumab Monotherapy in Participants With Advanced Adenocarcinoma of the Lung).
Investigational
Matched Synonyms: … protein comprising the n-terminal 100 amino acids of the lm acta protein (actan100), 5 tandem copies of a ... live-attenuated double-deleted (ladd) strain of listeria monocytogenes (lm .delta.acta/.delta.inlb) expressing a …
Matched Description: … is under investigation in clinical trial NCT03371381 (An Efficacy and Safety Study of JNJ-64041757, a …
Matched Description: … is under investigation in clinical trial NCT03371381 (An Efficacy and Safety Study of JNJ-64041757, a …
(S)-Rolipram
A phosphodiesterase inhibitor with antidepressant properties. [PubChem]
Experimental
Matched Iupac: … (4S)-4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one …
Matched Description: … A phosphodiesterase inhibitor with antidepressant properties. [PubChem] …
Matched Description: … A phosphodiesterase inhibitor with antidepressant properties. [PubChem] …
Displaying drugs 8451 - 8475 of 12915 in total