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Displaying drugs 826 - 850 of 1088 in total

Cefpodoxime

Cefpodoxime is an oral third generation cephalosporin antibiotic with effectiveness against most Gram positive and Gram negative bacteria. Commonly used to treat acute otitis media, pharyngitis, and sinusitis, cefpodoxime proxetil is a prodrug which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime.
Approved
Vet approved
Matched Description: … is an oral third generation cephalosporin antibiotic with effectiveness against most Gram positive and ... which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime. ... Commonly used to treat acute otitis media, pharyngitis, and sinusitis, cefpodoxime proxetil is a prodrug …
Matched Mixtures name: … TEXEF PLUS 100/62.5 MG FİLM KAPLI TABLET, 20 ADET ... TEXEF PLUS 200/125 MG FILM KAPLI TABLET, 20 ADET …
Matched Products: … DUCHESS 100 MG FILM TABLET, 20 ADET ... DOKSELIN 200 MG FILM TABLET, 14 ADET ... DUCHESS 200 MG FILM TABLET, 14 ADET …

Bosentan

Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.
Approved
Investigational
Matched Description: … blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … PROART FILM COATED TABLETS 125MG ... CLOKSAR 125 MG FILM TABLET, 56 TABLET ... DIAMOND 125 MG FILM TABLET, 112 ADET …

Zofenopril

Zofenopril is employed as both a cardioprotective and anti-hypertensive agent. It is an angiotensin-converting enzyme (ACE) inhibitor.
Approved
Matched Description: … Zofenopril is employed as both a cardioprotective and anti-hypertensive agent. …
Matched Mixtures name: … BIFRIL PLUS 30/12.5 MG FILM TABLET, 28 ADET ... BIFRIL PLUS 30/12.5 MG FILM TABLET, 84 ADET ... ZOPROTEC PLUS 30/12.5 MG FILM TABLET, 28 ADET …
Matched Categories: … ACE Inhibitors and Diuretics ... Amino Acids, Peptides, and Proteins ... zofenopril and diuretics ... zofenopril and nebivolol …
Matched Products: … BIFRIL 15 MG (FILM-COATED TABLETS) ... BIFRIL 30 MG (FILM-COATED TABLETS) ... BIFRIL 30 MG FILM TABLET, 14 ADET …

Sildenafil

In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The result of doing so allows cGMP present in both the penis and pulmonary vasculature to...
Approved
Investigational
Matched Description: … and the increased flow of blood into the spongy erectile tissue of the penis that consequently allows ... it to grow in size and become erect and rigid [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614 ... The result of doing so allows cGMP present in both the penis and pulmonary vasculature to elicit smooth …
Matched Mixtures name: … DAPOXIL 30/50 MG FILM KAPLI TABLET,18 FILM KAPLI TABLET ... DAPOKSEL 30 MG/50 MG FILM TABLET ,3 FILM TABLET ... DAPOKSEL 30 MG/50 MG FILM TABLET ,6 FILM TABLET …
Matched Products: … VULGAR 25 MG FILM TABLET, 4 FILM TABLET ... VULGAR 50 MG FILM TABLET, 4 FILM TABLET ... VULGAR 100 MG FILM TABLET, 4 FILM TABLET …

Sitagliptin

Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256]. The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon to improve control of blood sugar[FDA label,A2255]....
Approved
Investigational
Matched Description: … Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise ... The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon …
Matched Mixtures name: … Sitagliptin and metformin hydrochloride ... Sitagliptin and metformin hydrochloride ... Reddy-sitagliptin and Metformin Hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and sitagliptin ... sitagliptin and simvastatin ... sitagliptin and ertugliflozin ... pioglitazone and sitagliptin …
Matched Products: … PTİAGLİN 100 MG FİLM KAPLI TABLET ... İVOBRA 5 MG FİLM KAPLI TABLET, 56 ADET ... Sitavia Film Coated Tablet 100mg …

Memantine

Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's...
Approved
Investigational
Matched Description: … blocks the effects of glutamate, a neurotransmitter in the brain that leads to neuronal excitability and ... doubling every 20 years, the prevalence of Alzheimer's Disease is predicted to reach 66 million by 2030 and …
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Categories: … donepezil and memantine ... donepezil, memantine and Ginkgo folium …
Matched Products: … MENTAX 10 MG FILM TABLET,FILM TABLET, 100 ADET ... AXURA 5/10/15/20MG FILM ST ... ALMENTA 15MG FILM TABLET, 28 ADET …

Olaparib

Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and PARP2.[L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work by taking advantage of a defect in DNA repair in cancer cells with BRCA mutations and inducing cell death. Olaparib...
Approved
Matched Description: … Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and ... [L41100, L40908, L43792] It was first approved by the FDA and EU in December 2014,[A246020] and by Health ... [L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … LYNPARZA FILM-COATED TABLET 150MG ... LYNPARZA FILM-COATED TABLET 100MG ... Lynparza 150 mg Film-Coated Tablets …

Finerenone

Finerenone, or BAY 94-8862, is a mineralocorticoid receptor antagonist indicated to reduce the risk of sustained decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart attacks, and hospitalization due to heart failure in adults with chronic kidney disease associated with type II diabetes mellitus.[A236519,L34739] Patients with kidney...
Approved
Investigational
Matched Description: … [A236544] Spironolactone has low selectivity and affinity for the receptor; it dissociates quickly and ... [A236544] Eplerenone is more selective and has longer lasting effects. ... decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart attacks, and …
Matched Products: … KERENDIA FILM-COATED TABLET 10MG ... KERENDIA FILM-COATED TABLET 20MG ... KERENDİA 10 MG FİLM KAPLI TABLET, 98 ADET …

Prucalopride

Prucalopride is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and thus, it presents enterokinetic properties. The high selectivity of prucalopride allowed further development as it prevented the cardiac adverse reactions observed due to non-target effects of precedent therapies. Prucalopride was developed by Shire Development LLC...
Approved
Matched Description: … dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and ... A40250] in Canada on December 7, 2011 and by the FDA on December 17, 2018. ... [A40254] Prucalopride was developed by Shire Development LLC and approved for use in Europe in 2009,[ …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Resolor Film-coated Tablet 2 mg ... Resolor Film-coated Tablet 1 mg ... RESOLOR 1mg Film Coated Tablets …

Rivaroxaban

Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary. However there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15...
Approved
Matched Description: … Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. ... The 15 mg and 20 mg tablet should be taken with food. FDA approved on July 1, 2011. ... However there is no antidote available in the event of a major bleed. …
Matched Categories: … Blood and Blood Forming Organs ... rivaroxaban and acetylsalicylic acid …
Matched Products: … Xarelto 2.5mg Film-Coated Tablets ... Rivax 10mg Film Coated Tablets ... Rivax 20mg Film Coated Tablets …

Benidipine

Benidipine has the formula 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridine-dicarboxylic acid methyl 1-(phenylmethyl)-3-piperidinyl ester hydrochloride. It is a synthetic dihydropyridine derivative that has anti-hypertensive and anti-anginal actions. It was originated in Japan by Kyowa Hakko, it is submitted for FDA approval and it is currently available in some Asian countries like India and Japan.[L1385, L1386]
Experimental
Matched Description: … available in some Asian countries like India and Japan. ... It is a synthetic dihydropyridine derivative that has anti-hypertensive and anti-anginal actions. ... [A31948] It was originated in Japan by Kyowa Hakko, it is submitted for FDA approval and it is currently …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Products: … BENIPIN 4 MG FILM TABLET,TABLET, 30 ADET ... BENIPIN 8 MG FILM TABLET,TABLET, 30 ADET ... BENİTİDE 4 MG FİLM KAPLI TABLET, 30 ADET …

Abrocitinib

Abrocitinib is an oral small-molecule inhibitor of Janus kinase 1 (JAK1). Janus kinases are intracellular enzymes involved in transduction pathways that regulate hematopoiesis and immune cell function. The Janus kinase (JAK)–signal transducer and activator of transcription (STAT) signalling pathway plays a central role in the pathogenesis of a variety of...
Approved
Investigational
Matched Description: … Janus kinases are intracellular enzymes involved in transduction pathways that regulate hematopoiesis and ... [L39774] The Janus kinase (JAK)–signal transducer and activator of transcription (STAT) signalling pathway ... plays a central role in the pathogenesis of a variety of autoimmune and inflammatory diseases, including …
Matched Products: … Cibinqo 50mg Film-Coated Tablets ... Cibinqo 100mg Film-Coated Tablets ... Cibinqo 200mg Film-Coated Tablets …

Gefitinib

Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa.
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … VEIASU FILM-COATED TABLETS 250 MG ... Iressa 250mg Film-coated Tablet ... GEFTINAT FILM COATED TABLETS 250 MG …

Cefprozil

Cefprozil is a cephalosporin antibiotic that is commonly employed to treat a variety of bacterial infections, including those of the ear and skin, bronchitis, and others.
Approved
Matched Description: … skin, bronchitis, and others. ... antibiotic that is commonly employed to treat a variety of bacterial infections, including those of the ear and …
Matched Products: … PREFIX 250 MG FILM TABLET, 10 ADET ... PREFIX 250 MG FILM TABLET, 14 ADET ... PREFIX 250 MG FILM TABLET, 20 ADET …

Lornoxicam

Lornoxicam (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory and antipyretic properties. Lornoxicam differs from other oxicam compounds in its potent inhibition of prostaglandin biosynthesis, a property that explains the particularly pronounced efficacy of the drug. Lornoxicam is approved for use in Japan.
Approved
Investigational
Matched Description: … new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … XEFO 4 MG FILM KAPLI TABLET, 20 ADET ... XEFO RAPID 8 MG FILM KAPLI TABLET ... XEFO 8 MG FILM KAPLI TABLET, 20 ADET …

Ebastine

Ebastine is under investigation for the treatment of Irritable Bowel Syndrome (IBS). Ebastine has been investigated for the treatment of Urticaria.
Approved
Investigational
Matched Products: … EBAFIT 10 MG FILM KAPLI TABLET, 10 ADET ... KESTINE FILM-COATED TABLET 20MG ... EBAFIT 10 MG FILM KAPLI TABLET, 30 ADET …

Cefditoren

Cefditoren is an oral third-generation cephalosporin. It is commonly marketed under the trade name Spectracef by Cornerstone BioPharma.
Approved
Investigational
Matched Products: … CEFITEN 200 MG FILM TABLET, 10 ADET ... CEFITEN 400 MG FILM TABLET, 14 ADET ... CEFITEN 400 MG FILM TABLET, 20 ADET …

Axitinib

Axitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3). Through this mechanism of action, axitinib blocks angiogenesis, tumour growth and metastases. It is reported to exhibit potency that is 50-450 times higher than that of the first generation...
Approved
Investigational
Matched Description: … [L6676] Through this mechanism of action, axitinib blocks angiogenesis, tumour growth and metastases. ... [A179398] It is most commonly marketed under the name Inlyta® and is available in oral formulations. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Benzamides and benzamide derivatives …
Matched Products: … Inlyta Film-coated Tablets 1mg ... Inlyta Film-coated Tablets 5mg ... INLYTA 3 MG FİLM KAPLI TABLET, 28 ADET …

Donepezil

In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990. Donepezil, also known as Aricept, is a piperidine derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and in some...
Approved
Matched Description: … with [Memantine] in 2014 to manage moderate and severe forms of Alzheimer's dementia. ... derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and ... Donepezil was first approved by the FDA in 1996, and its extended-release form was approved in combination …
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Categories: … donepezil and memantine ... donepezil, memantine and Ginkgo folium …
Matched Products: … ANDEM 5 MG FILM TABLET, 14 ADET ... ANDEM 5 MG FILM TABLET, 28 ADET ... ANDEM 10 MG FILM TABLET, 14 ADET …

Lemborexant

Lemborexant is a novel dual orexin receptor antagonist used in the treatment of insomnia characterized by difficulties with sleep onset and/or sleep maintenance. Recent research in the field of sleep disorders has revealed that insomnia is likely driven not by the inability of the brain to "switch on" sleep-related circuits,...
Approved
Investigational
Matched Description: … receptors, lemborexant and other orexin antagonists (e.g. ... receptor antagonist used in the treatment of insomnia characterized by difficulties with sleep onset and ... [zopiclone], [zolpidem], benzodiazepines) focus on enhancing sleep drive via modulation of GABA and melatonin …
Matched Categories: … Hypnotics and Sedatives ... Sleep Initiation and Maintenance Disorders …
Matched Products: … DAYVIGO FILM-COATED TABLET 5MG ... DAYVIGO FILM-COATED TABLET 10MG ... Dayvigo 5mg Film coated tablet …

Abiraterone

Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis.[A3811, A260880, L40968] Abiraterone was first approved by the FDA and EMA on April, July, and September 2011, respectively. It is used to treat metastatic...
Approved
Matched Description: … ] and September 2011,[A260880] respectively. ... Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17 ... ), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... niraparib and abiraterone ... abiraterone and prednisolone ... Hormone Antagonists and Related Agents ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … ZYTIGA FILM-COATED TABLET 500MG ... ZYTIGA 500 MG (FILM-COATED TABLETS) ... ZYTIGA 500mg Film-Coated Tablet …

Roxadustat

Roxadustat is a first-in-class hypoxia-inducible factor prolyl hydroxylase inhibitor used to treat anemia associated with chronic kidney disease. It works by reducing the breakdown of the hypoxia-inducible factor (HIF), which is a transcription factor that stimulates red blood cell production in response to low oxygen levels. Roxadustat was first approved...
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … EVRENZO 20 MG FİLM KAPLI TABLET, 12 ADET ... EVRENZO 50 MG FİLM KAPLI TABLET, 12 ADET ... EVRENZO 70 MG FİLM KAPLI TABLET, 12 ADET …

Ribavirin

Producing a broad-spectrum activity against several RNA and DNA viruses, Ribavirin is a synthetic guanosine nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. It is primarily indicated for use in treating hepatitis C and viral hemorrhagic fevers. HCV is a single-stranded RNA virus that is categorized...
Approved
Matched Description: … The dual therapy was administered for 48 weeks in patients with genotype 1, 4, 5, and 6, and 24 weeks ... in patients with genotype 2 and 3 [A19626]. ... Producing a broad-spectrum activity against several RNA and DNA viruses, Ribavirin is a synthetic guanosine …
Matched Mixtures name: … Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules) …
Matched Categories: … Nucleosides and Nucleotides ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … Copegus film coated tablet 200mg ... VIRON 400 MG FİLM KAPLI TABLET, 56 ADET ... VİRANİS 200 MG FİLM TABLET, 70 ADET …

Dexketoprofen

Dexketoprofen is a non-steroidal anti-inflammatory drug. It is available in the various countries in Europe, Asia and Latin America. It has analgesic, antipyretic and anti-inflammatory properties .
Approved
Investigational
Matched Description: … It is available in the various countries in Europe, Asia and Latin America. ... It has analgesic, antipyretic and anti-inflammatory properties [L1298]. …
Matched Mixtures name: … INDEXPA SR 75/300MG FILM KAPLI TABLET, 10 SR FILM KAPLI TABLET ... INDEXPA SR 75/300MG FILM KAPLI TABLET, 20 SR FILM KAPLI TABLET ... SKUDEXA FILM-COATED TABLET 75 MG/25 MG …
Matched Categories: … Ketoprofen and isomer ... Antiinflammatory and Antirheumatic Products ... tramadol and dexketoprofen ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Products: … SERTOFEN 25 MG FILM TABLET ,FILM TABLET, 10 ADET ... SERTOFEN 25 MG FILM TABLET ,FILM TABLET, 20 ADET ... KETESSE 25MG FILM COATED TABLET …

Levetiracetam

Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders. It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs).[L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918]...
Approved
Matched Description: … It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated ... [L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918] and little-to-no ... choice over other AEDs, a class of drugs notorious for having generally narrow therapeutic indexes and …
Matched Products: … KEPPRA 500MG FILM COATED TABLET ... KEPPRA 1000MG FILM COATED TABLET ... Epivon film-coated tablets 250mg …
Displaying drugs 826 - 850 of 1088 in total