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Displaying drugs 8626 - 8650 of 11284 in total
Benzquinamide is a discontinued antiemetic compound with antihistaminic, mild anticholinergic, and sedative properties. The mechanism of action is not known, but presumably benzquinamide works via antagonism of muscarinic acetycholine receptors and histamine H1 receptors.
Withdrawn
Matched Iupac: … 3-(diethylcarbamoyl)-9,10-dimethoxy-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-yl acetate …
Experimental
Matched Name: … 4-[(Isopropylamino)Methyl]Phenylalanine …
Matched Iupac: … (2S)-2-amino-3-(4-{[(propan-2-yl)amino]methyl}phenyl)propanoic acid …
BMS-564929 is an investigational therapeutic agent built to be a selective androgen receptor modulator (SARM). So far, it has been developed by Bristol-Myers Squibb for the symptomatic treatment of andropause.
Experimental
Matched Iupac: … 4-[(7R,7aS)-7-hydroxy-1,3-dioxo-hexahydro-1H-pyrrolo[1,2-c]imidazol-2-yl]-2-chloro-3-methylbenzonitrile …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Name: … 4-(2,2,2-TRIFLUOROETHYL)-L-PHENYLALANINE …
Matched Iupac: … (2S)-2-amino-3-[4-(2,2,2-trifluoroethyl)phenyl]propanoic acid …
Ifetroban has been used in trials studying the treatment of Skin Diseases, Autoimmune Diseases, Pathologic Processes, Scleroderma, Limited, and Scleroderma, Diffuse, among others.
Investigational
Matched Iupac: … 3-(2-{[(1S,2R,3S,4R)-3-[4-(pentylcarbamoyl)-1,3-oxazol-2-yl]-7-oxabicyclo[2.2.1]heptan-2-yl]methyl}phenyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Glpg0492 is under investigation in clinical trial NCT01130818 (First-in-Human Single Ascending Dose of GLPG0492).
Investigational
Matched Iupac: … 4-[(4S)-4-(hydroxymethyl)-3-methyl-2,5-dioxo-4-phenylimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Iupac: … 3-chloro-4-(3-chloro-2-nitrophenyl)-1H-pyrrole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Name: … (2R,4S)-2-[(R)-BENZYLCARBAMOYL-PHENYLACETYL-METHYL]-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID …
Matched Iupac: … (2R,4S)-2-[(R)-(benzylcarbamoyl)(2-phenylacetamido)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic …
Ronacaleret is a calcium-sensing receptor antagonist.
Investigational
Matched Iupac: … 3-{3-[(2R)-3-{[1-(2,3-dihydro-1H-inden-2-yl)-2-methylpropan-2-yl]amino}-2-hydroxypropoxy]-4,5-difluorophenyl …
Experimental
Matched Synonyms: … 2-(4-morpholinoanilino)-6-cyclohexylaminopurine …
Matched Iupac: … N6-cyclohexyl-N2-[4-(morpholin-4-yl)phenyl]-9H-purine-2,6-diamine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Islatravir is under investigation in clinical trial NCT04233216 (Doravirine/islatravir (DOR/ISL) in Heavily Treatment-experienced (HTE) Participants for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-019)).
Investigational
Matched Synonyms: … 4'-ethynyl-2-fluoro-2'-deoxyadenosine …
Matched Iupac: … (2R,3S,5R)-5-(6-amino-2-fluoro-9H-purin-9-yl)-2-ethynyl-2-(hydroxymethyl)oxolan-3-ol …
Matched Description: … (HIV-1) Infection (MK-8591A-019)). ... (DOR/ISL) in Heavily Treatment-experienced (HTE) Participants for Human Immunodeficiency Virus Type 1
Clonixin is a non-steroidal anti-inflammatory drug.
Experimental
Matched Iupac: … 2-[(3-chloro-2-methylphenyl)amino]pyridine-3-carboxylic acid …
Matched Salts cas: … 55837-30-4
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Name: … N-(4-phenoxyphenyl)-2-[(pyridin-4-ylmethyl)amino]nicotinamide …
Matched Iupac: … N-(4-phenoxyphenyl)-2-{[(pyridin-4-yl)methyl]amino}pyridine-3-carboxamide …
Experimental
Matched Name: … N-(TRANS-4'-NITRO-4-STILBENYL)-N-METHYL-5-AMINO-PENTANOIC ACID …
Matched Iupac: … 5-[methyl({4-[(1E)-2-(4-nitrophenyl)ethenyl]phenyl})amino]pentanoic acid …
Pateclizumab is under investigation in clinical trial NCT01225393 (A Study to Evaluate the Efficacy and Safety of MLTA3698A in Combination With a Disease-Modifying Anti-Rheumatic Drug (DMARD) Compared With Adalimumab in Combination With a DMARD in Patients With Active Rheumatoid Arthritis).
Investigational
Agatolimod is under investigation in clinical trial NCT00471471 (Vaccine Therapy in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery).
Investigational
Experimental
Lorukafusp alfa is under investigation in clinical trial NCT01334515 (Biological Therapy, Sargramostim, and Isotretinoin in Treating Patients With Relapsed or Refractory Neuroblastoma).
Investigational
Hydroxyproline is a neutral heterocyclic protein amino acid. It is found in collagen and as such it is common in many gelatin products. Hydroxyproline is mostly used as a diagnostic marker of bone turnover and liver fibrosis. Therapeutically, hydroxyproline is being studied as an an experimental medicine but is approved...
Experimental
Matched Synonyms: … trans-4-Hydroxy-L-proline …
Matched Iupac: … (2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid …
Matched Mixtures name: … Ouhi Cell Power No 1 Essence ... Ouhi Cell Power No 1 Eye ... Gongjinhyang Mi Luxury Foundation 1
Experimental
Labetuzumab is a humanized monoclonal antibody to carcinoembryonic antigen that inhibits tumor growth. It is used in radioimmunotherapy.
Investigational
alpha-Hydroxylinoleic acid is under investigation in clinical trial NCT04431258 (ABTL0812 in Combination With FOLFIRINOX for First-line Treatment of Metastatic Pancreatic Study).
Investigational
L-deprenyl-D2 C-11 is under investigation in clinical trial NCT01701089 (A Study of RO4602522 in Patients With Alzheimer Disease and in Healthy Volunteers).
Investigational
Matched Iupac: … (11C)methyl[(2R)-1-phenylpropan-2-yl][(1,1-2H2)prop-2-yn-1-yl]amine …
TH0318 is a stabilized analogue of human GLP-1 (glucagon-like peptide-1) under investigation for the treatment of type 2 diabetes.
Investigational
Matched Synonyms: … ThGLP-1
Matched Description: … TH0318 is a stabilized analogue of human GLP-1 (glucagon-like peptide-1) under investigation for the …
The bafilomycins refer to a category of toxic macrolide antibiotics that are derivatives of Streptomyces griseus. These compounds all appear in the same fermentation and have similar biological activity. Bafilomycins are specific inhibitors of vacuolar-type H+-ATPase. (V-ATPase). The most commonly utilized bafilomycin is bafilomycin A1. This is a useful tool...
Experimental
Matched Iupac: … )oxan-2-yl]-3-hydroxypentan-2-yl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-1-oxacyclohexadeca-3,5,11,13 ... (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-16-[(2S,3R,4S)-4-[(2R,4R,5S,6R)-2,4-dihydroxy-5-methyl-6-(propan-2-yl …
Displaying drugs 8626 - 8650 of 11284 in total