Displaying drugs 851 - 875 of 923 in total
Isoliquiritigenin
Isoliquiritigenin is a precursor to several flavonones in many plants.
Experimental
Matched Synonyms: … (E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propene-1-one …
MALP-2
Investigational
Matched Synonyms: … L-lysine, s-((2r)-2,3-bis((1-oxohexadecyl)oxy)propyl)-l-cysteinylglycyl-l-asparaginyl-l-asparaginyl-l …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Edetic acid
A chelating agent (chelating agents) that sequesters a variety of polyvalent cations. It is used in pharmaceutical manufacturing and as a food additive.
Approved
Vet approved
Matched Synonyms: … N,N'-1,2-Ethane diylbis-(N-(carboxymethyl)glycine) …
Matched Description: … It is used in pharmaceutical manufacturing and as a food additive. …
Matched Categories: … Diet, Food, and Nutrition …
Matched Description: … It is used in pharmaceutical manufacturing and as a food additive. …
Matched Categories: … Diet, Food, and Nutrition …
Dexrazoxane
An antimitotic agent with immunosuppressive properties. Dexrazoxane, the (+)-enantiomorph of razoxane, provides cardioprotection against anthracycline toxicity. It appears to inhibit formation of a toxic iron-anthracycline complex. [PubChem]
The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the prevention or reduction in the incidence and...
Approved
Withdrawn
Matched Synonyms: … (+)-1,2-Bis(3,5-dioxo-1-piperazinyl)propane …
Matched Description: … [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the ... prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy. …
Matched Description: … [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the ... prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy. …
3-(4-hydroxy-3-imino-6-oxo-cyclohexa-1,4-dienyl)-alanine
Experimental
Matched Name: … 3-(4-hydroxy-3-imino-6-oxo-cyclohexa-1,4-dienyl)-alanine …
Ceritinib
Ceritinib is used for the treatment of adults with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) following failure (secondary to resistance or intolerance) of prior crizotinib therapy. About 4% of patients with NSCLC have a chromosomal rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like...
Approved
Matched Synonyms: … -{2-[(5-chloro-2-{[2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propane …
Matched Iupac: … 5-chloro-N2-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N4-[2-(propane-2-sulfonyl)phenyl]pyrimidine …
Matched Description: … rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like 4) and ... lymphoma kinase), which results in constitutive kinase activity that contributes to carcinogenesis and ... autophosphorylation of ALK, ALK-mediated phosphorylation of the downstream signaling protein STAT3, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Tyrosine Kinase Inhibitors ... ROS1 tyrosine kinase inhibitors ... Receptor Protein-Tyrosine Kinases, antagonists & inhibitors …
Matched Iupac: … 5-chloro-N2-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N4-[2-(propane-2-sulfonyl)phenyl]pyrimidine …
Matched Description: … rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like 4) and ... lymphoma kinase), which results in constitutive kinase activity that contributes to carcinogenesis and ... autophosphorylation of ALK, ALK-mediated phosphorylation of the downstream signaling protein STAT3, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Tyrosine Kinase Inhibitors ... ROS1 tyrosine kinase inhibitors ... Receptor Protein-Tyrosine Kinases, antagonists & inhibitors …
Valproic acid
Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. In 1963, a serendipitous discovery was made by George Carraz during his investigations into...
Approved
Investigational
Matched Description: … Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in ... [A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for ... [L6190]
Since then, it has been investigated for neuroprotective, anti-manic, and anti-migraine effects …
Matched Products: … VALKENE ... VALOIN INJECTION …
Matched Products: … VALKENE ... VALOIN INJECTION …
2,2-bis(4-hydroxy-3-tert-butylphenyl)propane
TBD has been used in trials studying the treatment of Adenocarcinoma.
Investigational
Matched Name: … 2,2-bis(4-hydroxy-3-tert-butylphenyl)propane …
3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol
Experimental
Matched Name: … 3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol …
Caspofungin
Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc. It is typically administered intravenously. It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal...
Approved
Matched Synonyms: … hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans-3-hydroxy-L-proline …
Matched Description: … It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan ... Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan ... Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug …
Matched Categories: … Amino Acids, Peptides, and Proteins …
N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)Isopipecolinic Acid Methyl Ester
Experimental
Matched Name: … N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)Isopipecolinic Acid Methyl Ester …
Celecoxib
Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in...
Approved
Investigational
Matched International brands: … Valdyne …
Matched Description: … [A181544] It is used to manage symptoms of various types of arthritis pain and in familial adenomatous ... [A181532] It is marketed by Pfizer under the brand name Celebrex, and was initially granted FDA approval ... selective COX-2 inhibitors (especially celecoxib), have been evaluated as potential cancer chemopreventive and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antineoplastic and Immunomodulating Agents ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... tramadol and celecoxib ... amlodipine and celecoxib …
Matched Description: … [A181544] It is used to manage symptoms of various types of arthritis pain and in familial adenomatous ... [A181532] It is marketed by Pfizer under the brand name Celebrex, and was initially granted FDA approval ... selective COX-2 inhibitors (especially celecoxib), have been evaluated as potential cancer chemopreventive and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antineoplastic and Immunomodulating Agents ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... tramadol and celecoxib ... amlodipine and celecoxib …
3-[N-[benzyloxycarbonyl]-phenylalaninyl-amino]-5-phenyl-pentane-1-sulfonylmethylbenzene
Experimental
Matched Name: … 3-[N-[benzyloxycarbonyl]-phenylalaninyl-amino]-5-phenyl-pentane-1-sulfonylmethylbenzene …
N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ALANINE
Experimental
Matched Name: … N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ALANINE …
(3R)-4-{[(3,4-dihydroxyphenyl)acetyl]oxy}-N-(2-formylindolizin-3-yl)-3-sulfino-D-valine
Experimental
Matched Name: … (3R)-4-{[(3,4-dihydroxyphenyl)acetyl]oxy}-N-(2-formylindolizin-3-yl)-3-sulfino-D-valine …
1-Hydroxy-2-S-glutathionyl-3-para-nitrophenoxy-propane
Experimental
Matched Name: … 1-Hydroxy-2-S-glutathionyl-3-para-nitrophenoxy-propane …
N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine
Experimental
Matched Name: … N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine …
Nerinetide
Na 1 is under investigation in clinical trial NCT00728182 (Evaluating Neuroprotection in Aneurysm Coiling Therapy).
Investigational
Matched Synonyms: … -ASPARTYL-L-VALINE ... L-VALINE, L-TYROSYLGLYCYL-L-ARGINYL-L-LYSYL-L-LYSYL-L-ARGINYL-L-ARGINYL-L-GLUTAMINYL-L-ARGINYL-L-ARGINYL-L-ARGINYL-L-LYSYL-L-LEUCYL-L-SERYL-L-SERYL-L-ISOLEUCYL-L …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
N-({(2S,3S)-3-[(BENZYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINE
Experimental
Matched Name: … N-({(2S,3S)-3-[(BENZYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINE …
Prenylamine
Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.
Approved
Withdrawn
Matched Synonyms: … 1-Phenyl-2-(1',1'-diphenylpropyl-3'-amino)propane …
Matched Description: … Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Description: … Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Theophylline
A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly...
Approved
Matched Description: … methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and ... Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated ... mainly for asthma, bronchospasm, and COPD. …
Matched Mixtures name: … Theophylline 4mg and 5% Dextrose Inj ... Theophylline 1.6mg and 5% Dextrose Inj ... Theophylline 0.8mg and 5% Dextrose Inj …
Matched Salts name: … Theophylline sodium glycinate …
Matched Categories: … Xanthines and Adrenergics ... theophylline and adrenergics …
Matched Products: … Theophylline in Dextrose …
Matched Mixtures name: … Theophylline 4mg and 5% Dextrose Inj ... Theophylline 1.6mg and 5% Dextrose Inj ... Theophylline 0.8mg and 5% Dextrose Inj …
Matched Salts name: … Theophylline sodium glycinate …
Matched Categories: … Xanthines and Adrenergics ... theophylline and adrenergics …
Matched Products: … Theophylline in Dextrose …
ABBV-CLS-7262
Investigational
Matched Synonyms: … fluorophenoxy)acetamido]bicyclo[2.2.2]octan-2- yl}oxy)methyl hydrogen phosphate - 2-amino-2- (hydroxymethyl)propane …
Matched Iupac: … sodium 2-amino-2-(hydroxymethyl)propane-1,3-diol {[(2S)-1,4-bis[2-(4-chloro-3-fluorophenoxy)acetamido …
Matched Iupac: … sodium 2-amino-2-(hydroxymethyl)propane-1,3-diol {[(2S)-1,4-bis[2-(4-chloro-3-fluorophenoxy)acetamido …
N-[3-[(1-Aminoethyl)(Hydroxy)Phosphoryl]-2-(1,1'-Biphenyl-4-Ylmethyl)Propanoyl]Alanine
Experimental
Matched Name: … N-[3-[(1-Aminoethyl)(Hydroxy)Phosphoryl]-2-(1,1'-Biphenyl-4-Ylmethyl)Propanoyl]Alanine …
N,N-[2,5-O-dibenzyl-glucaryl]-DI-[valinyl-aminomethanyl-pyridine]
Experimental
Matched Name: … N,N-[2,5-O-dibenzyl-glucaryl]-DI-[valinyl-aminomethanyl-pyridine] …
N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)-4-Acetyl-Piperazine
Experimental
Matched Name: … N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)-4-Acetyl-Piperazine …
Displaying drugs 851 - 875 of 923 in total