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Displaying drugs 851 - 875 of 5394 in total
Dasabuvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Matched Synonyms: … Sodium 3-(3-tert-butyl-4-methoxy-5-{6­ [(methylsulfonyl)amino]naphthalene-2-yl}phenyl)-2,6-dioxo-3,6 ... N-{6-[3-tert-butyl-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl]naphthalen-2-yl}methanesulfonamide …
Matched Iupac: … N-{6-[3-tert-butyl-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-2-methoxyphenyl]naphthalen-2-yl}methanesulfonamide …
Matched Description: … in combination with [DB09296], [DB09297], and [DB00503] for genotype 1b and with [DB00811] for genotype ... Dasabuvir is a non-nucleoside NS5B inhibitor which binds to the palm domain of NS5B and induces a conformational ... Dasabuvir is available as a fixed dose combination product with [DB09296], [DB09297], and [DB00503] ( …
Matched Salts cas: … 1456607-55-8 …
Matched Salts name: … Dasabuvir sodium ... Dasabuvir sodium monohydrate …
Matched Categories: … dasabuvir, ombitasvir, paritaprevir and ritonavir …
Matched Products: … EXVIERA 250 MG FILM KAPLI TABLET,56 TABLET …
Naratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. It is typically used for the treatment of migraine headaches.
Approved
Investigational
Matched Synonyms: … N-methyl-2-(3-(1-methylpiperiden-4-yl)indole-5-yl)ethanesulfonamide ... N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]-ethanesulfonamide …
Matched Iupac: … N-methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethane-1-sulfonamide …
Matched Description: … Naratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. …
Matched Salts name: … Naratriptan hydrochloride
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist ... Monoamine Oxidase A Substrates ... Serotonin 5-HT1 Receptor Agonists ... Selective Serotonin 5-HT1 Receptor Agonists …
Matched Products: … Naratriptan Hydrochloride ... Apo-naratriptan ... NARATRIPTAN AL 2.5MG …
AMPA is a specific agonist for the AMPA receptor.
Experimental
Matched Synonyms: … (S)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
Matched Iupac: … (2S)-2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl)propanoic acid
Matched Description: … AMPA is a specific agonist for the AMPA receptor. …
Experimental
Matched Synonyms: … [(5S,7R,8S,9R)-8,9-dihydroxy-2,4-dioxo-6-oxa-1,3-diazaspiro[4.4]non-7-yl]methyl dihydrogen phosphate
Matched Name: … Hydantocidin-5'-phosphate
Matched Iupac: … {[(5S,7R,8S,9R)-2,4,8,9-tetrahydroxy-6-oxa-1,3-diazaspiro[4.4]nona-1,3-dien-7-yl]methoxy}phosphonic acid
Experimental
Matched Name: … Ribulose-5-Phosphate
Matched Iupac: … {[(2R,3S)-2,3,5-trihydroxy-4-oxopentyl]oxy}phosphonic acid
Experimental
Matched Synonyms: … alpha-Ketomalonic acid ... Oxomalonic acid ... Ketomalonic acid
Matched Name: … Mesoxalic acid
Matched Iupac: … 2-oxopropanedioic acid
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids
Experimental
Matched Name: … Calcium fluoride
Matched Categories: … Fluorides ... Fluorine Compounds …
Experimental
Matched Synonyms: … 2'-guanylic acid ... Guanosine 2'-phosphate
Matched Iupac: … }phosphonic acid ... {[(2R,3R,4R,5R)-2-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Hydronidone has antifibrotic activity.
Investigational
Matched Synonyms: … N-(4-Hydroxyphenyl)-5-methyl-2-pyridone
Matched Iupac: … 1-(4-hydroxyphenyl)-5-methyl-1,2-dihydropyridin-2-one …
Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation.[A4979,T28] Exhibiting tissue-specific effects distinct from estradiol, raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM....
Approved
Investigational
Matched Description: … effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation ... and it does not cause endometrial proliferation. ... However, it has a negligible effect on altering the development and progression of breast cancer itself …
Matched Salts name: … Raloxifene Hydrochloride
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Raloxifene Hydrochloride ... Raloxifene hydrochloride ... Apo-raloxifene …
Experimental
Matched Synonyms: … Phosphate-32 ... Phosphate-32P …
Matched Name: … Phosphate ion P-32 …
Matched Iupac: … (32P)phosphate
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear,...
Approved
Investigational
Matched Description: … It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, ... mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and ... An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological …
Matched Salts name: … Papaverine hydrochloride
Matched Categories: … Alimentary Tract and Metabolism ... Papaverine and Derivatives ... Genito Urinary System and Sex Hormones …
Matched Products: … Papaverine Hydrochloride ... PAPAVERINE HYDROCHLORIDE ... Papaverine Hydrochloride Injection USP …
Aminoglycosides, many of which are derived directly from Streptomyces spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is notable for its use in treating chronic Pseudomonas aeruginosa infections in cystic fibrosis patients, as P. aeruginosa is notoriously inherently resistant to...
Approved
Investigational
Matched Synonyms: … O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribohexopyranosyl …
Matched Iupac: … (2S,3R,4S,5S,6R)-4-amino-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5
Matched Description: … such as β-lactams and cephalosporins. ... bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms ... in a variety of forms for administration by inhalation, injection, and external application to the eye …
Matched Salts cas: … 95188-93-5
Matched Mixtures name: … Tobramycin and Dexamethasone ... Tobramycin and Dexamethasone ... Tobramycin and Dexamethasone …
Matched Salts name: … Tobramycin hydrochloride
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index ... Drugs that are Mainly Renally Excreted …
Matched Products: … Tobramycin in Sodium Chloride ... Aj-tobramycin ... Apo-tobramycin …
Mycophenolic acid is a potent immunosuppressant agent that inhibits de novo purine biosynthesis. It was derived from Penicillium stoloniferum, and has also shown antibacterial, antifungal and antiviral properties. . Mycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacrolimus)...
Approved
Investigational
Matched Synonyms: … (e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid ... Acido micofenolico ... Mycophenolic acid
Matched Name: … Mycophenolic acid
Matched Iupac: … (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid
Matched Description: … [A249180] However, mycophenolic acid treatment is more expensive and requires therapeutic drug monitoring ... and antiviral properties. ... to optimize efficacy and minimize toxicity. …
Matched Salts name: … Mycophenolate sodium
Matched Categories: … Mycophenolic Acid and Prodrugs ... Antineoplastic and Immunomodulating Agents ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids
Matched Products: … Apo-mycophenolic Acid ... MYCOPHENOLATMOFET AL 250MG ... MYCOPHENOLATMOFET AL 500MG …
Pentetic acid, also known as diethylenetriaminepentaacetic acid (DTPA), is a synthetic polyamino carboxylic acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable DTPA-metal ion complexes. DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment...
Approved
Matched Synonyms: … DTP-A ... Pentetic acid ... Diethylene triamine pentaacetic acid
Matched Name: … Pentetic acid
Matched Iupac: … 2-[bis({2-[bis(carboxymethyl)amino]ethyl})amino]acetic acid
Matched Description: … acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable DTPA-metal ... DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment ... [L2242] DPTA was developed by the pharmaceutical company CIS US and FDA approved on April 14, 2004. …
Matched Salts cas: … 11082-38-5
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Drugs that are Mainly Renally Excreted ... Compounds used in a research, industrial, or household setting …
Matched Products: … Pentetic Acid ... MON.DTPA.KIT 7.8 MG IV ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 5 ADET ... TECHNESCAN DTPA 20.8 MG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ, 5 ADET …
Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins and polypeptides. It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. Like most proteolytic enzymes, chymotrypsin is activated from its inactive zymogen precursor, chymotrypsinogen, in presence...
Approved
Vet approved
Matched Synonyms: … Chymotrypsin A ... alpha-Chymotrypsin …
Matched Description: … and polypeptides. ... It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. ... Chymotrypsin contains both the catalytic triad and oxyanion hole, and the tertiary structure of chymotrypsin …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs …
Experimental
Matched Synonyms: … 3'-Azido-3'-deoxythymidine 5'-phosphate ... Zdv 5'-monophosphate ... Zidovudine 5'-monophosphate …
Matched Iupac: … acid ... {[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}phosphonic …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Name: … Alpha-D-Galactose-1-Phosphate
Matched Iupac: … {[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phosphonic acid
The use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets from the market on August 5, 1982.
Approved
Withdrawn
Matched Synonyms: … 2-(4-Chlorophenyl)-alpha-methyl-5-benzoxazoleacetic acid ... (1)-2-(4-Chlorophenyl)benzoxazole-5-propionic acid ... 2-(4-chlorophenyl)-α-methyl-5-benzoxazoleacetic acid
Matched Iupac: … 2-[2-(4-chlorophenyl)-1,3-benzoxazol-5-yl]propanoic acid
Matched Description: … The use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic ... The holder of the approved application voluntarily withdrew Oraflex tablets from the market on August 5, …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids
Aphidicolin is an antimitotic and antiviral metabolite of the mould Cephalosporium aphidicola. It inhibits DNA polymerase alpha and blocks DNA replication.[A259157, A259162]
Investigational
Matched Synonyms: … .,5.alpha.,17.alpha ... 8,11a-methano-11ah-cyclohepta(a)naphthalene-4,9-dimethanol, tetradecahydro-3,9-dihydroxy-4,11b-dimethyl ... 9,15-cyclo-c,18-dinor-14,15-secoandrostane-4,17-dimethanol, 3,17-dihydroxy-4-methyl-, (3.alpha.,4.alpha
Matched Iupac: … (1S,2S,5R,6R,7R,10S,12R,13R)-6,13-bis(hydroxymethyl)-2,6-dimethyltetracyclo[10.3.1.0^{1,10}.0^{2,7}]hexadecane …
Matched Description: … It inhibits DNA polymerase alpha and blocks DNA replication.[A259157, A259162] ... Aphidicolin is an antimitotic and antiviral metabolite of the mould _Cephalosporium aphidicola_. …
alpha-Hydroxylinoleic acid is under investigation in clinical trial NCT04431258 (ABTL0812 in Combination With FOLFIRINOX for First-line Treatment of Metastatic Pancreatic Study).
Investigational
Matched Synonyms: … .ALPHA.-HYDROXYLINOLEIC ACID ... (9Z,12Z)-2-HYDROXY-9,12-OCTADECADIENOIC ACID ... 9,12-OCTADECADIENOIC ACID, 2-HYDROXY-, (9Z,12Z)- …
Matched Name: … alpha-Hydroxylinoleic acid
Matched Iupac: … (9Z,12Z)-2-hydroxyoctadeca-9,12-dienoic acid
Matched Description: … alpha-Hydroxylinoleic acid is under investigation in clinical trial NCT04431258 (ABTL0812 in Combination …
Matched Salts name: … ABTL-0812 Sodium
Matched Categories: … Fatty Acids ... Fatty Acids, Omega-6 ... Fatty Acids, Essential ... Fatty Acids, Unsaturated …
A nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides. In animals, UDP glucuronic acid is used for formation of many glucosiduronides with various aglycones. [PubChem]
Experimental
Matched Synonyms: … Uridine-5'-diphosphate-glucuronic acid ... UDP-alpha-D-glucuronate ... UDP-Glucuronic Acid
Matched Name: … UDP-alpha-D-glucuronic acid
Matched Iupac: … -2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-3,4,5-trihydroxyoxane-2-carboxylic acid ... (2S,3S,4S,5R,6R)-6-({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan …
Matched Description: … A nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis ... It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides. ... In animals, UDP glucuronic acid is used for formation of many glucosiduronides with various aglycones …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Micafungin is an antifungal drug. It belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall.
Approved
Investigational
Matched Iupac: … hexaazatricyclo[22.3.0.0^{9,13}]heptacosan-6-yl]-1,2-dihydroxyethyl]-2-hydroxyphenyl}oxidanesulfonic acid ... {5-[(1S,2S)-2-[(3S,6S,9S,11R,15S,18S,20R,21R,24S,25S,26S)-3-[(1R)-2-carbamoyl-1-hydroxyethyl]-11,20,21,25 ... -tetrahydroxy-15-[(1R)-1-hydroxyethyl]-26-methyl-2,5,8,14,17,23-hexaoxo-18-(4-{5-[4-(pentyloxy)phenyl …
Matched Description: … It belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting ... Micafungin is an antifungal drug. ... the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall. …
Matched Salts name: … Micafungin sodium
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Micafungin in Sodium Chloride ... Micafungin Sodium for Injection ... MYCAMINE FOR INJECTION 50 MG/VIAL …
Colesevelam is a bile acid sequestrant. Colesevelam is used with exercise and diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in the blood. It works by binding bile acids in the intestine. Bile acids are made when cholesterol is broken...
Approved
Matched Description: … Colesevelam is used with exercise and diet changes (restriction of cholesterol and fat intake) to reduce ... the amount of cholesterol and certain fatty substances in the blood. ... Colesevelam is a bile acid sequestrant. …
Matched Salts name: … Colesevelam hydrochloride
Matched Categories: … Bile Acid Sequestrants ... Bile-acid Binding Activity …
Matched Products: … Apo-colesevelam ... Colesevelam Hydrochloride ... Colesevelam hydrochloride
Ioxitalamate is an ionic iodinated contrast medium. It is a first-generation contrast media formed by an ionic monomer with a high osmolarity of 1500-1800 mOsm/kg. Ioxitalamic acid in the salt forms of sodium and meglumine was developed by Liebel-Flarshem Canada Inc and approved by Health Canada in 1995. Until the...
Approved
Matched Synonyms: … Ioxitalamic acid ... Acide ioxitalamique ... Acido ioxitalamico …
Matched Name: … Ioxitalamic acid
Matched Iupac: … 3-acetamido-5-[(2-hydroxyethyl)carbamoyl]-2,4,6-triiodobenzoic acid
Matched Description: … [A33006] Ioxitalamic acid in the salt forms of sodium and meglumine was developed by Liebel-Flarshem ... Canada Inc and approved by Health Canada in 1995. ... [A27209] It is a first-generation contrast media formed by an ionic monomer with a high osmolarity of …
Matched Salts name: … Sodium ioxitalamate …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Acids, Carbocyclic ... Carboxylic Acids ... ioxitalamic acid ... Triiodobenzoic Acids
Matched Products: … TELEBRIX 35 FLAKON, 50 ML …
Displaying drugs 851 - 875 of 5394 in total