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Displaying drugs 851 - 875 of 4274 in total
Recombinant human heparan-N-sulfatase (rhHNS) is under investigation for the treatment mucopolysaccharidosis type IIIA.
Investigational
Matched Synonyms: … Recombinant human heparan-N-sulfatase …
Matched Name: … Heparan-N-sulfatase (human, recombinant) …
Matched Description: … Recombinant human heparan-N-sulfatase (rhHNS) is under investigation for the treatment mucopolysaccharidosis …
AMT-101 is a recombinant human interleukin-10 fusion protein.
Investigational
Matched Synonyms: … Recombinant human interleukin-10 fusion protein …
Matched Description: … AMT-101 is a recombinant human interleukin-10 fusion protein. …
Perampanel is a noncompetitive AMPA glutamate receptor antagonist. It is marketed under the name Fycompa™ and is indicated as an adjunct in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures. The FDA label includes an important black-boxed warning...
Approved
Matched Description: … It is marketed under the name Fycompa™ and is indicated as an adjunct in patients over 12 years old for ... The FDA label includes an important black-boxed warning of serious or life-threatening behavioral and
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2B6 Inducers ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP3A Inducers ... Cytochrome P-450 CYP3A4 Inducers …
Matched Products: … FYCOMPA (4 MG) ... FYCOMPA® 4 MG ... Fypalan 4 mg-Filmtabletten …
Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.
Approved
Investigational
Matched Description: … Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is ... used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis. …
Matched Salts cas: … 19767-45-4
Matched Mixtures name: … IFEX and MESNEX ... IFEX and MESNEX ... IFEX and MESNEX …
Matched Categories: … Cough and Cold Preparations …
Matched Products: … UROMITEXAN 400 MG/4ML AMPOLLAS ... UROPROT® 400 MG/4 ML SOLUCION INYECTABLE ... UROMITEXAN 400 MG/4 ML ENJEKSİYONLUK ÇÖZELTİ, 15 ADET …
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human receptor tyrosine kinase ror-1) (human-mus musculus monoclonal uc-961 ... .gamma.1-chain), disulfide with human-mus musculus monoclonal uc-961 .kappa. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Lenvatinib is a receptor tyrosine kinase (RTK) inhibitor that inhibits the kinase activities of vascular endothelial growth factor (VEGF) receptors VEGFR1 (FLT1), VEGFR2 (KDR), and VEGFR3 (FLT4). Lenvatinib also inhibits other RTKs that have been implicated in pathogenic angiogenesis, tumor growth, and cancer progression in addition to their normal cellular...
Approved
Investigational
Matched Synonyms: … 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide …
Matched Iupac: … 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide …
Matched Description: … 4; the platelet derived growth factor receptor alpha (PDGFRα), KIT, and RET. ... differentiation, and in pathogenic angiogenesis, lymphogenesis, tumour growth and cancer progression ... kinase activities of vascular endothelial growth factor (VEGF) receptors VEGFR1 (FLT1), VEGFR2 (KDR), and
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Inhibitors ... Cytochrome P-450 CYP2B6 Inhibitors ... Cytochrome P-450 CYP3A Inducers …
Matched Products: … เล็นวิมา (4 มิลลิกรัม) ... LENVIMA HARD CAPSULE 4MG ... Lenvima 4 mg Hard Capsules …
Investigational
Matched Synonyms: … ), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL .KAPPA. ... chain), disulfide with human-mouse monoclonal κ-chain, dimer ... HEAVY CHAIN), DISULFIDE WITH HUMAN MOUSE MONOCLONAL HU96 110 .KAPPA. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Dulaglutide, marketed by Eli Lilly as Trulicity, is a once-weekly subcutaneous glucagon-like peptide-1 (GLP-1) receptor agonist designed using recombinant DNA technology; it has been approved as an adjunct therapy to diet and exercise in the management of 2 diabetes (T2DM). Dulaglutide was initially approved by the FDA in 2014, and...
Approved
Investigational
Matched Description: … agonist designed using recombinant DNA technology; it has been approved as an adjunct therapy to diet and ... [A236070] Dulaglutide was initially approved by the FDA in 2014, and in February 2020 was approved for ... use in patients with T2DM and multiple cardiovascular risk factors for the prevention of cardiovascular …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … TRULİCİTY 1.5 MG/0.5 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 4 ADET ... TRULİCİTY 0.75 MG/0.5 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 4 ADET …
Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Investigational
Matched Description: … 36% for genotype 1 and 59% for genotypes 2-6 after 48 weeks of treatment. ... Peginterferon alfa-2a is derived from the alfa-2a moeity of recombinant human interferon and acts by ... (AASLD) and the Infectious Diseases Society of America (IDSA) no longer recommend Peginterferon alfa …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins ... Cytochrome P-450 CYP1A2 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors …
Matched Products: … PEGASYS 135 MCG/0.5 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ŞIRINGA, 4 ADET ... PEGASYS 180 MCG/0.5 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ŞIRINGA, 4 ADET …
Talditercept alfa is under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy).
Investigational
Matched Synonyms: … protein with adnectin, anti-(human growth differentiation factor 8) (human clone bms-986089 fibronectin ... Bivalent Anti-Human Myostatin Adnectin-Igg1 ... Bms-986089 (fully human anti-myostatin adnectin) …
Matched Description: … under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and
Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. In 1963, a serendipitous discovery was made by George Carraz during his investigations into...
Approved
Investigational
Matched Synonyms: … 4-heptanecarboxylic acid …
Matched Description: … Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in ... [A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for ... It is currently a compound of interest in the field of oncology for its anti-proliferative effects and
Matched Salts cas: … 62959-43-7 …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Inhibitors ... Cytochrome P-450 CYP2A6 Substrates ... Cytochrome P-450 CYP2B6 Substrates ... Cytochrome P-450 CYP3A Inhibitors …
Matched Products: … EPİLEPKİN 400 MG/4 ML I.V. ... SODIUM VALPROATE AGUETTANT 400 MG/4 ML ... DEPAKİN 400 MG/4 ML IV ENJEKSİYONLUK ÇÖZELTİ İÇİN LİYOFLİZE TOZ VE ÇÖZÜCÜ, 4 ADET …
Endostar is under investigation for the treatment of Nasopharyngeal Carcinoma. Endostar has been investigated for the treatment of Non-small Cell Lung Cancer.
Investigational
Matched Synonyms: … Recombinant human endostatin protein ... N-TERMINAL-MGGSHHHHH-ENDOSTATIN (HUMAN RECOMBINANT) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. This recombinant form differs from...
Approved
Matched Synonyms: … Recombinant human interleukin-2 ... Recombinant interleukin-2 human ... 125-L-serine-2-133-interleukin 2 (human reduced) …
Matched Description: … Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression ... clone encodes a modified human interleukin-2. ... recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins ... Cytochrome P-450 CYP2E1 Inhibitors ... Cytochrome P-450 CYP3A Inhibitors …
Dorzolamide is a non-bacteriostatic sulfonamide derivative and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular hypertension. It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. Unlike oral CA inhibitors, dorzolamide...
Approved
Matched Synonyms: … (4S,trans)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide ... 4S,6S-dorzolamide ... (4S,6S)-4-ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic …
Matched Iupac: … (2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H-1lambda6-thieno[2,3-b]thiopyran-6-sulfonamide …
Matched Description: … Dorzolamide is a non-bacteriostatic sulfonamide derivative [A1304] and topical carbonic anhydrase (CA ... ) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular ... [L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure …
Matched Mixtures name: … Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide HCl and Timolol Maleate ... Dorzolamide Hydrochloride and Timolol Maleate …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates …
Clesrovimab is under investigation in clinical trial NCT04938830 (Clesrovimab (MK-1654) in Infants and Children at Increased Risk for Severe Respiratory Syncytial Virus (RSV) Disease (MK-1654-007)).
Investigational
Matched Synonyms: … f protein) (human monoclonal rb1 .gamma.1-chain), disulfide with human monoclonal rb1 .kappa. ... Immunoglobulin g1 (262-tyrosine,264-threonine,266-glutamic acid), anti-(human respiratory syncytial virus …
Matched Description: … Clesrovimab is under investigation in clinical trial NCT04938830 (Clesrovimab (MK-1654) in Infants and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination With Capsid Inhibitor Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection).
Investigational
Matched Synonyms: … Immunoglobulin g1 (434-leucine,440-serine), anti-(human immunodeficiency virus 1 envelope protein gp120env ... ) (human monoclonal 8c11-62a12 .gamma.1-chain), disulfide with human monoclonal 8c11-62a12 .kappa. …
Matched Description: … Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination …
A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.
Approved
Investigational
Matched Description: … A muscarinic antagonist that has effects in both the central and peripheral nervous systems. ... It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. ... It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine …
Matched Salts cas: … 7085-45-2 …
Matched Categories: … Cytochrome P-450 CYP2D6 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP2D6 Inhibitors (strength unknown) …
Matched Products: … AKINETON 4MG ... AKINETON 4MG RETARD ... AKINETON RETARD 4MG
Domiphen bromide is a quaternary ammonium compound that is predominantly employed as a topically administered antiseptic agent.
Approved
Experimental
Matched Mixtures name: … Mouthwash and Gargle ... Lander Orl Hygienic Mwh and Gargle …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … Ora-septic Cerises Loz 1.5mg …
Salbutamol (Albuterol [USAN]) is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Salbutamol is formulated as a...
Approved
Vet approved
Matched Iupac: … 4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol …
Matched Description: … USAN]) is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and ... Salbutamol is formulated as a racemic mixture of the R- and S-isomers. ... The R-isomer has 150 times greater affinity for the beta2-receptor than the S-isomer and the S-isomer …
Matched Mixtures name: … Ipratropium Bromide and Albuterol Sulfate ... Ipratropium Bromide and Albuterol Sulfate ... Ipratropium Bromide and Albuterol Sulfate …
Matched Categories: … salbutamol and budesonide ... salbutamol and beclometasone ... salbutamol and sodium cromoglicate ... salbutamol and ipratropium bromide ... Cytochrome P-450 CYP3A Inhibitors …
Matched Products: … Salbu-4 - Tab 4mg ... LASAL 4 ... AZMACON 4
Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.[FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus.[A181802,T116] Ketoconazole was first approved in an oral formulation...
Approved
Investigational
Matched Iupac: … 1-[4-(4-{[2-(2,4-dichlorophenyl)-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin …
Matched Description: … Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal ... [clotrimazole], due to its broad spectrum and good absorption. ... synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and
Matched Mixtures name: … SPORUM-D ... Ketoconazole 2% / Niacinamide 4% …
Matched Categories: … Sex Hormones and Insulins ... Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics ... Metabolic Side Effects of Drugs and Substances ... Cytochrome P-450 Substrates …
Matched Products: … SPOREX ... SPORUM® CASP 2% CHAMPU ... KETORAL % 2 KREM, 40 G …
VIS-410 is under investigation in clinical trial NCT03040141 (Study of Efficacy and Safety of IV VIS410 Plus Oseltamivir Versus Oseltamivir in Hospitalized Adults With Influenza A).
Investigational
Matched Synonyms: … WITH HUMAN MONOCLONAL VIS410 .KAPPA. ... IMMUNOGLOBULIN G1, ANTI-(INFLUENZA HEMAGGLUTININ) (HUMAN MONOCLONAL VIS410 .GAMMA.1-CHAIN), DISULFIDE …
Matched Name: … VIS-410
Matched Description: … VIS-410 is under investigation in clinical trial NCT03040141 (Study of Efficacy and Safety of IV VIS410 …
Molsidomine is an orally active, long-acting vasodilator, which belongs to the class of medications known as syndnones. Interestingly, it is being studied as being a preventive measure in cerebral infarction .
Approved
Investigational
Matched Iupac: … 5-[(ethoxycarbonyl)azanidyl]-3-(morpholin-4-yl)-1,2,3lambda5-oxadiazol-3-ylium …
Matched Products: … CORVATON FORTE 4MG ... MOLSIDOMIN 4 HEUMANN ... Molsidolat 4 mg Tabletten …
Investigational
Matched Synonyms: … Proteinase inhibitor m/nei (synthetic human) ... Recombinant human neutrophil inhibitor (hne) ... Human recombinant neutrophil elastase inhibitor, homologue of the second kunitz domain of inter-alpha-trypsin …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Warfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration. Although originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the most frequently prescribed oral anticoagulant in North America. Warfarin has several properties that should be noted when used medicinally,...
Approved
Matched Synonyms: … 4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin …
Matched Iupac: … 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one …
Matched Description: … , and drug interactions have also been documented with warfarin use. ... during pregnancy which can result in fetal bleeding, spontaneous abortion, preterm birth, stillbirth, and ... Additional adverse effects such as necrosis, purple toe syndrome, osteoporosis, valve and artery calcification …
Matched Categories: … Blood and Blood Forming Organs ... Warfarin and isomers ... 4-Hydroxycoumarins ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates …
Matched Products: … เบฟาริน 4 ... มาฟอแรน 4 มก. ... Coumadin Tab 4mg
Domvanalimab is under investigation in clinical trial NCT05502237 (Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1 (236-alanine,237-alanine,de-c-terminal-lysine), anti-(human receptor tigit)(human-mus ... musculus monoclonal ab154 .gamma.1-chain), disulfide with human-mus musculus monoclonal ab154 .kappa …
Matched Description: … Domvanalimab is under investigation in clinical trial NCT05502237 (Zimberelimab and Domvanalimab in Combination …
Displaying drugs 851 - 875 of 4274 in total