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Displaying drugs 8951 - 8975 of 9542 in total
Verpasep caltespen is a recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from Mycobacterium bovis, and the human papilloma viral (HPV) protein E7. Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be used to design vaccines against a...
Investigational
Becatecarin is a derivative of rebeccamycin.
Investigational
Matched Synonyms: … 6-(2-(DIETHYLAMINO)ETHYL)-REBECCAMYCIN …
Matched Iupac: … -2-yl]-3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa-1(16),2(10),4,6,8,11 ... 5,21-dichloro-13-[2-(diethylamino)ethyl]-3-[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Betameprodine is an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I of illegal substances. The stereoisomer alphameprodine is similarly classified, and was more widely used (both are referred to as Meprodine). Betameprodine is a structural analogue of meperidine. It exerts physiological effects characteristic of opioids,...
Experimental
Illicit
Matched Synonyms: … beta-1-Methyl-3-ethyl-4-phenyl-4-propionoxy-piperidin ... beta-3-Ethyl-1-methyl-4-phenyl-4-propionoxypiperidine …
Matched Iupac: … (3R,4R)-3-ethyl-1-methyl-4-phenylpiperidin-4-yl propanoate …
Investigational
Matched Synonyms: … -methyl-4-phenyl-1-piperidineethanol ... 1-piperidineethanol, 4-hydroxy-.alpha.-(4-hydroxyphenyl)-.beta.-methyl-4-phenyl-, (s-(r*,r*))- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Name: … D-naphthyl-1-acetamido boronic acid alanine …
Matched Iupac: … [(2S)-2-amino-2-carboxyethoxy][(1S)-1-acetamido-2-(naphthalen-1-yl)ethyl]dihydroxyboranuide …
Experimental
Matched Name: … L-naphthyl-1-acetamido boronic acid alanine …
Matched Iupac: … [(2S)-2-amino-2-carboxyethoxy][(1R)-1-acetamido-2-(naphthalen-1-yl)ethyl]dihydroxyboranuide …
Experimental
Matched Iupac: … (2S)-2-[({[(2R,3S,4S,5S)-5-{[(2R,3R,4R)-5-{4-[(6R,6aS,7S)-3-amino-6,7-dimethyl-1-oxo-1H,2H,5H,6H,6aH, ... 7H,8H,9H-imidazo[1,5-f]pteridin-8-yl]phenyl}-2,3,4-trihydroxypentyl]oxy}-3,4-dihydroxyoxolan-2-yl]methoxy …
Entinostat is under investigation for the treatment and other of Volunteers, Breast Cancer, Human Volunteers, and Normal Volunteers. Entinostat has been investigated for the treatment of Non-Small Lung Cancer, Epigenetic Therapy.
Investigational
Matched Synonyms: … N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide ... N-[[4-[(2-aminoanilino)-oxomethyl]phenyl]methyl]carbamic acid 3-pyridinylmethyl ester …
Matched Iupac: … (pyridin-3-yl)methyl N-({4-[(2-aminophenyl)carbamoyl]phenyl}methyl)carbamate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Girentuximab is a monoclonal chimeric (mouse/human) antibody directed against carbonic anhydrase IX, an antigen expressed in 95% of clear cell renal cell carcinomas (RCC).
Investigational
Experimental
Matched Synonyms: … Chloride(1-) …
XEN-D0501 is a tetrahydronaphthyl urea-based selective TRPV1 antagonist being investigated for the treatment of erythromelalgia.
Investigational
HH-009 is a recombinant human IgG4 monoclonal antibody against FGF19 being studied for the treatment of hepatocellular carcinoma.
Investigational
The Coronavirus-Like Particle COVID-19 Vaccine is in development and testing through Meidcago in Quebec City, Canada. The vaccine was developed by creating SARS-Cov-2 virus-like particles (CoVLPs), which mimic the structure of the virus without carrying the genetic components required for infection. VLPs are thought to have multiple mechanisms involving the...
Investigational
Matched Description: … The vaccine was developed by creating SARS-Cov-2 virus-like particles (CoVLPs), which mimic the structure ... A Phase 1 clinical trial was launched in July 2020 evaluating the safety, tolerability, and immunogenicity …
Vet approved
Matched Iupac: … -2-yl]-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.5⁷.3⁵]pentadec-13-en-9-yl]-3-hydroxy-4-methyl ... -5-oxooctan-2-yl]-5-methyloxan-2-yl]butanoic acid ... (2R)-2-[(2R,5S,6R)-6-[(2S,3S,4S,6R)-6-[(2S,5S,7R,9S,10S,12R,15R)-2-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyloxan …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ala-geninthiocin is a novel thiopeptide antibacterial compound derived from marine Streptomyces species. It has exhibited potent in vitro activity against gram-positive bacteria including Staphylococcus aureus, Bacillus subtilis, Mycobacterium smegmatis, and Micrococcus luteus.
Experimental
Matched Iupac: … N-[(1S)-1-carbamoylethyl]-2-{[(14S,17Z,27S)-17-ethylidene-14-[(1S)-1-hydroxyethyl]-27-(2-hydroxypropan ... -2-yl)-33-methyl-24,30,37,40-tetramethylidene-12,15,22,25,28,35,38-heptaoxo-19,32,42-trioxa-9-thia-3,13,16,23,26,29,36,39,44,45,46,47 ... -dodecaazahexacyclo[39.2.1.1^{8,11}.1^{18,21}.1^{31,34}.0^{2,7}]heptatetraconta-1(43),2,4,6,8(47),10,18 ... (46),20,31(45),33,41(44)-undecaen-4-yl]formamido}prop-2-enamide …
Experimental
Matched Name: … 6-CARBAMIMIDOYL-4-(3-HYDROXY-2-METHYL-BENZOYLAMINO)-NAPHTHALENE-2-CARBOXYLIC ACID METHYL ESTER …
Matched Iupac: … methyl 6-carbamimidoyl-4-(3-hydroxy-2-methylbenzamido)naphthalene-2-carboxylate …
Experimental
Matched Synonyms: … 2-acetamidopropionic acid ... (S)-2-(acetylamino)propanoic acid …
Matched Iupac: … (2S)-2-acetamidopropanoic acid …
Tomaralimab is under investigation in clinical trial NCT01794663 (Placebo-Controlled Study to Evaluate the Safety and Efficacy of OPN-305 in Preventing Delayed Renal Graft Function).
Investigational
Matched Synonyms: … Humanized IGG4 monoclonal antibody against toll-like receptor 2 for prevention of ischemia/reperfusion …
Investigational
DHEA sulfate is the major steroid of the fetal adrenal. DHEA-S is the principal adrenal androgen and is secreted together with cortisol under the control of ACTH and prolactin. DHEA-S is elevated with hyperprolactinemia.
Investigational
Matched Iupac: … [(3aS,3bR,7S,9aR,9bS,11aS)-9a,11a-dimethyl-1-oxo-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta …
Matched Salts cas: … 1099-87-2
Experimental
Matched Synonyms: … 1-O-Methyl-beta-D-glucopyranoside …
Matched Iupac: … (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-methoxyoxane-3,4,5-triol …
Experimental
Matched Synonyms: … alpha-L-1-Methyl-fucose …
Matched Iupac: … (2R,3S,4R,5S,6S)-2-methoxy-6-methyloxane-3,4,5-triol …
Reloxaliase is a crystalline formulation of oxalate decarboxylase derived from Bacillus Subtilis. Reloxaliase is under investigation in clinical trial NCT03456830 (Evaluate ALLN-177 in Patients With Enteric Hyperoxaluria).
Investigational
Displaying drugs 8951 - 8975 of 9542 in total