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Displaying drugs 8951 - 8975 of 11986 in total

Paclitaxel trevatide

Three paclitaxel molecules linked by a cleavable succinyl ester linkage to a brain peptide vector, Angiopep-2, conjugate named ANG1005.
Investigational

Japanese encephalitis vaccine (live, attenuated)

Experimental

ABO-202

Investigational

Indium In-111 satumomab pendetide

Tumor associated glycoprotein (TAG) 72 (B72.3) monoclonal antibody conjugated with Indium 111 for radioimaging colon tumors. Satumomab Pendetide (trade name: OncoScint®) is no longer commercially available.
Experimental
Withdrawn

Ginkgo biloba leaf oil

Ginkgo biloba leaf oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental

Milataxel

Milataxel has been used in trials studying the treatment of Mesothelioma.
Investigational
Matched Iupac: … (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-(acetyloxy)-15-{[(2R,3R)-3-{[(tert-butoxy)carbonyl]amino}-3-(furan- …

Paclitaxel ceribate

Investigational
Matched Iupac: … (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-9-{[(2,3-dihydroxypropoxy)carbonyl]oxy}-1-hydroxy ... -15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo …

Elacytarabine

Elacytarabine is a fatty acid derivative of cytarabine, an approved cytotoxic cancer drug. Cytarabine has limitations such as minimal uptake in solid tumours and is only used to treat leukaemia. Elacytarabine is designed to overcome this limitation and has shown considerable uptake in solid tumour cells. Elacytarabine is a patented...
Investigational
Matched Iupac: … [(2R,3S,4S,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl (9E)-octadec …

KP-1461

KP-1461 is a potent, non-chain-terminating, mutagenic deoxyribonucleoside analogue. Designated a DNA covert nucleoside, the drug consists of a modified base that incorporates randomly into HIV and pairs with multiple bases.
Investigational
Matched Iupac: … heptyl N-{5-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-oxo-1,4,5,6-tetrahydro-1,3,5-triazin …

Netivudine

Netivudine has been used in trials studying the treatment of Chickenpox and HIV Infections.
Investigational
Matched Iupac: … 1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(prop-1-yn-1-yl)-1,2,3,4-tetrahydropyrimidine …

Acebilustat

Acebilustat is under investigation in clinical trial NCT01748838 (Phase 1 Study Assessing the Safety and Tolerability of CTX-4430).
Investigational
Matched Iupac: … 4-{[(1S,4S)-5-({4-[4-(1,3-oxazol-2-yl)phenoxy]phenyl}methyl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]methyl …

Hydrolyzed soy protein

Experimental

Incadronic acid

Incadronate, or YM-175, is a nitrogen containing bisphosphonate. Along with being investigated to treat hypercalcemia of malignancy, it has also been investigated in the treatment of myeloma, leukemia, and other cancers.[A14426,A14431,A14427,A202769] Incadronic acid was first described in the literature in 1991.
Experimental
Matched Salts cas: … 138330-18-4 …

Eritoran

Eritoran is a structural analogue of the lipid A portion of lipopolysaccharide (LPS). It is being developed by Eisai Research Institute of Boston for the treatment of severe sepsis.
Investigational
Matched Iupac: … {[(2R,3R,4R,5S,6R)-4-(decyloxy)-5-hydroxy-6-({[(2R,3R,4R,5S,6R)-4-{[(3R)-3-methoxydecyl]oxy}-6-(methoxymethyl ... )-3-[(11Z)-octadec-11-enamido]-5-(phosphonooxy)oxan-2-yl]oxy}methyl)-3-(3-oxotetradecanamido)oxan-2-yl …
Matched Categories: … Toll-Like Receptor 4, antagonists & inhibitors …

N-{2-[(4'-CYANO-1,1'-BIPHENYL-4-YL)OXY]ETHYL}-N'-HYDROXY-N-METHYLUREA

Experimental
Matched Name: … N-{2-[(4'-CYANO-1,1'-BIPHENYL-4-YL)OXY]ETHYL}-N'-HYDROXY-N-METHYLUREA …
Matched Iupac: … 1-[2-({4'-cyano-[1,1'-biphenyl]-4-yl}oxy)ethyl]-3-hydroxy-1-methylurea …

Laquinimod

Laquinimod is an immunomodulator developed by Active Biotech and produced by Teva Pharmaceutical Industries. It is currently under development in phase III trials for treatment of multiple sclerosis as an oral therapy, like fingolimod. It has been shown to reduce disease activity on magnetic resonance imaging and to be well...
Investigational
Matched Iupac: … 5-chloro-N-ethyl-4-hydroxy-1-methyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide …

Barusiban

Barusiban has been used in trials studying the treatment of Infertility and In Vitro Fertilisation (IVF) Treatment.
Investigational
Matched Iupac: … -4-carboxamide ... (4S,7S,10S,13S,16R)-N-[(2S)-5-amino-1-hydroxypentan-2-yl]-10-[(2R)-butan-2-yl]-13-[(2S)-butan-2-yl]-7 ... -(carbamoylmethyl)-16-[(1H-indol-3-yl)methyl]-N-methyl-6,9,12,15,18-pentaoxo-1-thia-5,8,11,14,17-pentaazacycloicosane …

Reloxaliase

Reloxaliase is a crystalline formulation of oxalate decarboxylase derived from Bacillus Subtilis. Reloxaliase is under investigation in clinical trial NCT03456830 (Evaluate ALLN-177 in Patients With Enteric Hyperoxaluria).
Investigational

4-guanidinobenzoic acid

Experimental
Matched Synonyms: … 4-Guanidino-benzoic acid …
Matched Name: … 4-guanidinobenzoic acid …
Matched Iupac: … 4-carbamimidamidobenzoic acid …

4-Hydroxybutan-1-Aminium

Experimental
Matched Name: … 4-Hydroxybutan-1-Aminium …
Matched Iupac: … 4-hydroxybutan-1-aminium …

Glucosamine 4-Phosphate

Experimental
Matched Name: … Glucosamine 4-Phosphate …
Matched Iupac: … {[(2R,3S,4R,5R,6R)-5-amino-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}phosphonic acid …

4-(1H-IMIDAZOL-1-YL)PHENOL

Experimental
Matched Name: … 4-(1H-IMIDAZOL-1-YL)PHENOL …
Matched Iupac: … 4-(1H-imidazol-1-yl)phenol …

Biphenylalanine

Experimental
Matched Iupac: … (2S)-2-amino-3-{[1,1'-biphenyl]-4-yl}propanoic acid …

Vofopitant

Vofopitant has been used in trials studying the treatment of PTSD, Primary Insomnia, and Sleep Initiation and Maintenance Disorders.
Investigational
Matched Iupac: … ,3S)-N-({2-methoxy-5-[5-(trifluoromethyl)-1H-1,2,3,4-tetrazol-1-yl]phenyl}methyl)-2-phenylpiperidin-3- …

Zidebactam

Zidebactam is under investigation in clinical trial NCT02674347 (MAD Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Intravenous Zidebactam in Healthy Adults).
Investigational
Matched Iupac: … [(1R,2S,5R)-7-oxo-2-({[(3R)-piperidin-3-yl]formohydrazido}carbonyl)-1,6-diazabicyclo[3.2.1]octan-6-yl …
Displaying drugs 8951 - 8975 of 11986 in total