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Displaying drugs 876 - 900 of 1438 in total

C-peptide

C-peptide is under investigation in clinical trial NCT00278980 (Effect of C-peptide on Diabetic Peripheral Neuropathy).
Investigational
Matched Synonyms: … Human c-peptide ... Human proinsulin c-peptide ... Proinsulin c-peptide (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Zolmitriptan

Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor agonists used to treat acute migraine.[A462, L12978] Sumatriptan was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. This led to the development of second-generation triptans, including almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, and zolmitriptan. Triptans...
Approved
Investigational
Matched Description: … It is currently available in both tablet and nasal spray forms.[L12978] ... A462, L12978] [Sumatriptan] was the first triptan to be developed, but had poor oral bioavailability and ... [A193791] Triptans can be administered alone or in combination with an NSAID like [naproxen], and represent …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist ... Serotonin Agents ... Serotonin Modulators ... Selective Serotonin Agonists ... Serotonin Receptor Agonists …
Matched Products: … ZOLMITRIPTAN 1A PHAR 5MG ... ZOLMITRIPTAN 1A PHAR 2.5MG ... Zolmitriptan 1A Pharma 2,5 mg - Filmtabletten …

Mebendazole

A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Approved
Vet approved
Matched Description: … A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Matched Products: … GAMAX TABLETAS ... GAMAX SUSPENSIÓN …

Clervonafusp alfa

Investigational
Matched Synonyms: … Immunoglobulin g1, (humanized monoclonal 3e10 .gamma.1-chain fab fragment) fusion protein with 67-952 ... -glucosidase (human recombinant), disulfide with humanized monoclonal 3e10 .kappa.-chain ... cell-penetrating humanized fab fragment targeting the equilibrative nucleoside transporter 2 (ent2), fused with a human …

Nitroarginine

An inhibitor of nitric oxide synthetase which has been shown to prevent glutamate toxicity. Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced alterations in brain energy and ammonia metabolites. (Neurochem Res 1995:200(4):451-6)
Experimental
Investigational
Matched Synonyms: … N(gamma)-nitro-L-arginine …
Matched Description: … alterations in brain energy and ammonia metabolites. ... Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Lovastatin

Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite derived synthetically from a fermentation product of Aspergillus terreus. Originally named Mevinolin, lovastatin belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid...
Approved
Investigational
Matched Description: … Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite ... belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and ... of metabolic reactions involved in the production of several compounds involved in lipid metabolism and …
Matched Categories: … lovastatin and nicotinic acid …
Matched Products: … LOVASTATIN 1A PHARMA 10MG ... LOVASTATIN 1A PHARMA 20MG ... LOVASTATIN 1A PHARMA 40MG …

Propiverine

Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB) . Overactive bladder (OAB) is a chronic condition of the lower urinary tract characterized by urinary urgency, increased frequency of urination, and nocturia (frequent waking during the...
Approved
Investigational
Matched Description: … OAB has a negative impact on quality of life and may lead to leakage and inconvenient urinary accidents ... prevalence in men and women. ... condition of the lower urinary tract characterized by urinary urgency, increased frequency of urination, and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … PROPIVERIN 1A PHARMA 5MG ... PROPIVERIN 1A PHARMA 15MG …

Evening primrose oil

Evening primrose oil comes from the extraction from Oenothera biennis seeds and it is commonly used as an alternative source for omega-6 essential fatty acids. In its composition it presents some fatty acids such as DB00132 and DB13854. Evening primrose oil has been filled for the FDA by Humanetics Corporation...
Investigational
Nutraceutical
Matched Description: … Evening primrose oil comes from the extraction from _Oenothera biennis_ seeds and it is commonly used ... In its composition it presents some fatty acids such as [DB00132] and [DB13854]. …
Matched Mixtures name: … Gamma Oil ... OGAMIX(Evening primrose oil 500 mg, Lecithin oil 500 mg, Fish oil 125 mgand Vitamin E 10 mg Soft Gelatin …
Matched Products: … Vitalita Evening Primrose Oil 1000mg Softgel …

Lisinopril

Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.[L8384,L8387,L8390] Lisinopril and captopril are the only ACEIs that are not prodrugs. It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system.[A184781,A184808,A184817] ACEIs are commonly used as a...
Approved
Investigational
Matched Description: … Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and ... [L8384,L8387,L8390] Lisinopril and [captopril] are the only ACEIs that are not prodrugs. …
Matched Mixtures name: … LISINOPRIL 1A PLUS 10/12.5 ... LISINOPRIL 1A PLUS 10/12.5 ... LISINOPRIL 1A PLUS 20/12.5 …
Matched Categories: … ACE Inhibitors and Diuretics ... ACE Inhibitors and Calcium Channel Blockers ... Amino Acids, Peptides, and Proteins ... lisinopril and diuretics ... lisinopril and amlodipine …
Matched Products: … LISINOPRIL 5 1A PHARMA ... LISINOPRIL 10 1A PHARMA ... LISINOPRIL 20 1A PHARMA …

Mapatumumab

Mapatumumab is under investigation in clinical trial NCT00094848 (Study of TRM-1 (TRAIL-R1 Monoclonal Antibody) in Subjects With Relapsed or Refractory Non-hodgkin's Lymphoma (NHL)).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human trail-r1) (human monoclonal trm-1 heavy chain), disulfide with human monoclonal ... Immunoglobulin g1, anti-(human cytokine receptor dr4 (death receceptor 4)) (human monoclonal trm-1 heavy ... Immunoglobulin g1, anti-(human cytokine receptor dr4 (death receceptor 4)) (human monoclonal trm-1 heavy …
Matched Categories: … Amino Acids, Peptides, and Proteins …

RHCC10

RHCC10 is a recombinant human Clara cell protein.
Investigational
Matched Synonyms: … Recombinant human club cell protein ... Recombinant human Clara cell 10 kDa protein …
Matched Description: … RHCC10 is a recombinant human Clara cell protein. …

Endostatin

Investigational
Matched Synonyms: … Recombinant human endostatin …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …

Remestemcel-L

Remestemcel-L is a third-party, off-the-shelf suspension of ex-vivo cultured adult human mesenchymal stem cells intended for intravenous infusion. The mesenchymal stem cells are derived from the bone marrow of unrelated and human leukocyte antigen (HLA)–unmatched healthy adult donors and have the ability to differentiate into different tissue cells. It was...
Approved
Investigational
Matched Synonyms: … Adult human mesenchymal stem cells ... Allogeneic human mesenchymal stem cell …
Matched Description: … The mesenchymal stem cells are derived from the bone marrow of unrelated and human leukocyte antigen ... Human mesenchymal stem cells (hMSCs) serve to down-regulate inflammatory responses and produce anti-inflammatory ... cytokines and growth factors to promote tissue repair [A31818]. …

Mangostin

Mangostin is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … 7-o-methyl-.gamma.-mangostin …

Ramipril

Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII)....
Approved
Matched Description: … It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. ... ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... Ramipril may be used in the treatment of hypertension, congestive heart failure, nephropathy, and to …
Matched Mixtures name: … RAMIPRIL 1A PH PLU2.5/12.5 ... RAMIPRIL 1A PH PLU2.5/12.5 ... RAMIPRIL 1A PH PLU2.5/12.5 …
Matched Categories: … ACE Inhibitors and Diuretics ... ACE Inhibitors and Calcium Channel Blockers ... ramipril and felodipine ... ramipril and amlodipine ... ramipril and bisoprolol …
Matched Products: … RAMIPRIL 1A PHARMA 5 MG ... RAMIPRIL 1A PHARMA 10 MG ... RAMIPRIL 1A PHARMA 2.5 MG …

Flecainide

Flecainide is a Class I anti-arrhythmic agent like encainide and propafenone. Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics. It is used to prevent supraventricular and ventricular arrhythmias, as well as paroxysmal atrial fibrillation and flutter.[L8878,L5056] Flecainide was granted FDA...
Approved
Withdrawn
Matched Description: … fibrillation and flutter. ... Flecainide is a Class I anti-arrhythmic agent like [encainide] and [propafenone]. ... [A186880] Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate …
Matched Products: … FLECAINID 1A PHARMA 50MG ... FLECAINID 1A PHARMA 100MG …

Candesartan

Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is available as a prodrug in the form of candesartan cilexetil.
Experimental
Matched Mixtures name: … EUROPRES - D 16 MG / 12.5 MG TABLETA. …
Matched Categories: … candesartan and diuretics ... Angiotensin II receptor blockers (ARBs) and diuretics ... candesartan and amlodipine ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... atorvastatin, amlodipine and candesartan …
Matched Products: … CANDESARTAN 1A PHARMA 4MG ... CANDESARTAN 1A PHARMA 8MG ... CANDESARTAN 1A PHARMA 16MG …

Hydrochloric acid

Experimental
Matched Synonyms: … Chlorure d'hydrogène …
Matched Iupac: … hydrogen chloride …
Matched Categories: … Chlorine Compounds ... Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …

Elotuzumab

Elotuzumab is a humanized IgG1 (Immunoglobulin G) monoclonal antibody indicated in combination with lenalidomide and dexamethasone for the treatment of patients with multiple myeloma who have received one to three prior therapies. Elotuzumab targets SLAMF7, also known as Signaling Lymphocytic Activation Molecule Family member 7, a cell surface glycoprotein. Elotuzumab...
Approved
Matched Synonyms: … Immunoglobulin G1, anti-(human protein CS1) (human-mouse HuLuc63 heavy chain), disulfide with human-mouse …
Matched Description: … Food and Drug Administration. ... IgG1 heavy and kappa light chain frameworks. ... a humanized IgG1 (Immunoglobulin G) monoclonal antibody indicated in combination with lenalidomide and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

Dabigatran etexilate

Dabigatran etexilate is an oral prodrug that is hydrolyzed to the competitive and reversible direct thrombin inhibitor dabigatran.[A177463, A6970, L34675, L34680] Dabigatran etexilate may be used to decrease the risk of venous thromboembolic events in patients in whom anticoagulation therapy is indicated. In contrast to warfarin, because its anticoagulant effects...
Approved
Matched Description: … Dabigatran etexilate is an oral prodrug that is hydrolyzed to the competitive and reversible direct thrombin …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … Dabigatranetexilat 1A Pharma 75 mg - Hartkapseln ... Dabigatranetexilat 1A Pharma 110 mg - Hartkapseln ... Dabigatranetexilat 1A Pharma 150 mg - Hartkapseln …

Human Menstrual Blood-derived Stem Cells

Stem cells are self-renewing and proliferate without differentiation, with the two major groups being embryonic stem cells (ESCs) and adult stem cells (ASC). Differentiation occurs under different conditions into different cell types. ESCs are from the inner cell mass of blastocysts while ASCs are deposited into adult tissues with restricted...
Investigational
Matched Name: … Human Menstrual Blood-derived Stem Cells …
Matched Description: … embryonic stem cells (ESCs) and adult stem cells (ASC). ... Stem cells are self-renewing and proliferate without differentiation, with the two major groups being ... These cells possess a high rate of proliferation and multi-lineage differentiation potency. …

Human Recombinant Bone Morphogenetic Protein 4

Investigational
Matched Synonyms: … RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN 4 …
Matched Name: … Human Recombinant Bone Morphogenetic Protein 4 …

Human Embryonic Stem Cell-derived Astrocytes

Investigational
Matched Name: … Human Embryonic Stem Cell-derived Astrocytes …

Recombinant human palmitoyl protein thioesterase-1

Investigational
Matched Name: … Recombinant human palmitoyl protein thioesterase-1 …

Pravastatin

Pravastatin is the 6-alpha-hydroxy acid form of mevastatin. Pravastatin was firstly approved in 1991 becoming the second available statin in the United States. It was the first statin administered as the active form and not as a prodrug. This drug was developed by Sankyo Co. Ltd.; however, the first approved...
Approved
Matched Description: … It was the first statin administered as the active form and not as a prodrug. ... Ltd.; however, the first approved pravastatin product was developed by Bristol Myers Squibb and FDA approved ... The manufacturing process is followed by the hydrolysis of the lactone group and the biological hydroxylation …
Matched Categories: … pravastatin and ezetimibe ... pravastatin and fenofibrate ... pravastatin and acetylsalicylic acid ... pravastatin, ezetimibe and fenofibrate …
Matched Products: … PRAVASTATIN 1A PHARMA 10MG ... PRAVASTATIN 1A PHARMA 20MG ... PRAVASTATIN 1A PHARMA 30MG …
Displaying drugs 876 - 900 of 1438 in total