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Displaying drugs 876 - 900 of 2133 in total
Bemcentinib has been investigated for the treatment of Non-Small Cell Lung Cancer.
Investigational
Matched Synonyms: … (S)-1-(6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N3-(7-(pyrrolidin-1-yl)- 6,7,8,9-tetrahydro …
Investigational
Matched Synonyms: … L-ergothioneine ... L-(+)-ergothioneine ... L(+)-ergothioneine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Molybdenum cofactor deficiency (MoCD) is an exceptionally rare autosomal recessive disorder resulting in a deficiency of three molybdenum-dependent enzymes: sulfite oxidase (SOX), xanthine dehydrogenase, and aldehyde oxidase. Signs and symptoms begin shortly after birth and are caused by a build-up of toxic sulfites resulting from a lack of SOX activity.[A230088,L32163]...
Approved
Matched Synonyms: … C(PMP) …
Matched Iupac: … (4aR,5aR,11aR,12aS)-8-amino-2,12,12-trihydroxy-4,4a,5a,6,7,10,11,11a,12,12a-decahydro-2H-1,3,5-trioxa …
Matched Description: … resulting from a lack of SOX activity. ... recessive disorder resulting in a deficiency of three molybdenum-dependent enzymes: sulfite oxidase (SOX ... [A230088] Signs and symptoms begin shortly after birth and are caused by a build-up of toxic sulfites …
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …
Alanyl Glutamine is under investigation in clinical trial NCT00338221 (Clinical Trial of Alanyl-Glutamine or Glycine in Children With Persistent Diarrhea or Malnutrition).
Investigational
Matched Synonyms: … L-Alanyl-L-glutamine ... N(2)-L-Alanyl-L-glutamine …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Blood Substitutes and Perfusion Solutions …
A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin.
Experimental
Matched Synonyms: … (R)-3-(p-Hydroxyphenyl)alanine ... (R)-2-Amino-3-(p-hydroxyphenyl)propionic acid …
Matched Description: … It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin. …
Gimatecan is an orally available 7-t-butoxyiminomethyl-substituted lipophilic camptothecin derivative.
Investigational
Matched Synonyms: … -3,14-dioxo-, 11-[O-(1,1-dimethylethyl)oxime], (4S)- ... (4S)-11-[(E)-(tert-butoxyimino)methyl]-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline ... -ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1-H-pyrano[3',4':6,7]-indolizino-[1,2-b]-quinoline-11
L-Baclofen has been used in trials studying the treatment of Trigeminal Neuralgia.
Investigational
Matched Synonyms: … (S)-Baclofen …
Matched Name: … L-Baclofen …
Matched Description: … L-Baclofen has been used in trials studying the treatment of Trigeminal Neuralgia. …
Sunobinop is under investigation in clinical trial NCT04035200 (Safety, Tolerability and Efficacy Study of V117957 in Subjects With Insomnia Associated With Alcohol Cessation).
Investigational
Matched Synonyms: … 4-((1r,1'r,3r,3'r,5s,5's)-9'-aza(3,9'- bi(bicyclo(3.3.1)nonan))-3'-yl)-3-oxo-3,4- dihydroquinoxaline- …
Matched Description: … Sunobinop is under investigation in clinical trial NCT04035200 (Safety, Tolerability and Efficacy Study …
Pipotiazine has actions similar to those of other phenothiazines. Among the different phenothiazine derivatives, it appears to be less sedating and to have a weak propensity for causing hypotension or potentiating the effects of CNS depressants and anesthetics. However, it produces a high incidence of extra pyramidal reactions. It is...
Approved
Investigational
Matched Description: … for causing hypotension or potentiating the effects of CNS depressants and anesthetics. ... Among the different phenothiazine derivatives, it appears to be less sedating and to have a weak propensity ... Symptoms of overdose include severe extrapyramidal manifestations, hypotension, lethargy and sedation …
Matched Products: … Piportil L4 ... PIPORTIL® L4 INYECTABLE 1ML ... PIPORTIL ® L-4SOLUCION INYECTABLE AL 2.5% (100 MG). …
Investigational
Matched Synonyms: … r-metHuGDNF …
Adherex's biotechnology compound, ADH-1, targets N-cadherin, a protein present on certain tumor cells and established tumor blood vessels. ADH-1 is currently in clinical development in a combination program with a range of chemotherapeutic agents to investigate the synergistic effects noted in our preclinical models. At the end of 2006, the...
Investigational
Matched Synonyms: … Cys-His-Ala-Val-Cys ... l-cysteinamide, n-acetyl-l-cysteinyl-l-histidyl-l-alanyl-l-valyl-, cyclic (1-5)-disulfide …
Matched Description: … and organisms. ... well-defined shape and become loosely adherent, flattened and migratory. ... Adherex's biotechnology compound, ADH-1, targets N-cadherin, a protein present on certain tumor cells and
Experimental
Matched Name: … (R)-tacrine(10)-hupyridone …
A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012.
Approved
Matched Description: … prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and
Matched Mixtures name: … TAPCOM-S OPHTHALMIC SOLUTION ... TAPCOM-S ophthalmic solution 15 micrograms/ml + 5 mg/ml, solution in single-dose container …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … TAFLOTAN-S OPHTHALMIC SOLUTION 0.0015% ... TAFLOTAN-S ophthalmic solution 0.0015% (single-dose container) …
Experimental
Matched Synonyms: … Protease-S ... Seaprose-S
Investigational
Matched Synonyms: … -2,1-ethanediyl))tris(5b,6,7,12b,13,14-hexahydro-6-hydroxy-13-methyl-, (5br,5'br,5''br,6s,6's,6''s,12bs ... (1,3)benzodioxolo(5,6-c)-1,3-dioxolo(4,5-i)phenanthridinium, 13,13',13''-(phosphinothioylidynetris(imino …
Approved
Vet approved
Matched Iupac: … ,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl propanoate ... (1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1-[2-(acetyloxy)acetyl]-10-hydroxy-5,9a,11a-trimethyl-7-oxo-1H,2H,3H …
Matched Products: … ECTOPIX S %0.1 ÇÖZELTİ, 20ML ... ADVANTAN S % 0.1 COZELTI, 50 ML ... ADVANTAN S % 0.1 COZELTI, 20 ML …
Levodopa is a prodrug of dopamine that is administered to patients with Parkinson's due to its ability to cross the blood-brain barrier[Label]. Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally administered with a dopa decarboxylase inhibitor like carbidopa to prevent...
Approved
Matched Synonyms: … L-DOPA ... 3-Hydroxy-L-tyrosine ... Dihydroxy-L-phenylalanine …
Matched Description: … Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally ... Once past the blood-brain barrier, levodopa is metabolized to dopamine and supplements the low endogenous ... The first developed drug product that was approved by the FDA was a levodopa and carbidopa combined product …
Matched Mixtures name: … LEVO/CA/EN 100/25/200 STD ... LEVO/CA/ENT100/25/200 STD ... LEVO/CA/ENT100/25/200 STD
Matched Categories: … Amino Acids, Peptides, and Proteins ... Dopa and Dopa Derivatives ... levodopa and decarboxylase inhibitor ... levodopa, decarboxylase inhibitor and COMT inhibitor …
Theanine, a precursor of ethylamine, is found in green tea. It is under investigation in clinical trial NCT00291070 (Effects of L-Theanine in Boys With ADHD).
Investigational
Matched Synonyms: … L-theanine ... N-ethyl-L-glutamine ... N5-ethyl-L-glutamine …
Matched Description: … It is under investigation in clinical trial NCT00291070 (Effects of L-Theanine in Boys With ADHD). …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Seproxetine is also known as (S)-norfluoxetine. It is a selective serotonin reuptake inhibitor (SSRI). It is an active metabolite of fluoxetine. Seproxetine was being investigated by Eli Lilly as an antidepressant but development was never completed and the drug was never marketed.
Investigational
Matched Synonyms: … (S)-norfluoxetine …
Matched Description: … Seproxetine was being investigated by Eli Lilly as an antidepressant but development was never completed and ... Seproxetine is also known as (S)-norfluoxetine. …
PCS-499 is under investigation in clinical trial NCT01487109 (A Phase 2 Study to Evaluate the Safety and Efficacy of CTP-499 in Type 2 Diabetic Nephropathy Patients).
Investigational
Matched Synonyms: … Deuterated S-lisofylline …
Matched Description: … PCS-499 is under investigation in clinical trial NCT01487109 (A Phase 2 Study to Evaluate the Safety and ... Efficacy of CTP-499 in Type 2 Diabetic Nephropathy Patients). …
5-Hydroxytryptophan (5-HTP), also known as oxitriptan (INN), is a naturally occurring amino acid and metabolic intermediate in the synthesis of serotonin and melatonin. 5-HTP is sold over-the-counter in the United Kingdom, United States and Canada as a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, and...
Approved
Investigational
Nutraceutical
Matched Synonyms: … L-5-HTP ... 5-hydroxy-L-tryptophan ... L-5 Hydroxytrytophan …
Matched Description: … suppressant, and sleep aid, and is also marketed in many European countries for the indication of major ... 5-Hydroxytryptophan (5-HTP), also known as oxitriptan (INN), is a naturally occurring amino acid and ... metabolic intermediate in the synthesis of serotonin and melatonin. 5-HTP is sold over-the-counter in …
Matched Categories: … Amino Acids, Peptides, and Proteins …
DS-1211 is a potent and selective novel small molecule tissue-nonspecific alkaline phosphatase (TNAP) inhibitor.
Investigational
Matched Synonyms: … Ac-D-Leu-OH ... ACETYLLEUCINE, (R)- ... N-Acetyl-R-leucine …
Matched Description: … DS-1211 is a potent and selective novel small molecule tissue-nonspecific alkaline phosphatase (TNAP) …
Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland.
Experimental
Investigational
Matched Synonyms: … 7β-acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-one …
Matched Description: … Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. ... Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant ... activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland …
Imiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist. Imiquimod is commonly used topically to treat warts on the skin of the genital and anal areas. Imiquimod does not cure warts, and new warts may appear during treatment. Imiquimod does not fight the viruses that...
Approved
Investigational
Matched International brands: … Li Di ... Tian Rui
Matched Synonyms: … 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine ... 4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline …
Matched Iupac: … 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine …
Matched Description: … Miquimod is also used to treat a skin condition of the face and scalp called actinic keratoses and certain ... Imiquimod does not cure warts, and new warts may appear during treatment. ... Imiquimod is commonly used topically to treat warts on the skin of the genital and anal areas. …
Matched Categories: … Skin and Mucous Membrane Agents …
Matched Products: … Truemed Group LLC
Levobetaxolol is a beta-blocker used to lower the pressure in the eye to treat conditions such as glaucoma. It was marketed as a 0.5% ophthalmic solution of levobetaxolol hydrochloride under the trade name Betaxon but has been discontinued.
Approved
Investigational
Matched Synonyms: … (S)-betaxolol …
Displaying drugs 876 - 900 of 2133 in total