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Displaying drugs 876 - 900 of 1152 in total
Investigational
Matched Synonyms: … β) (human-Mus musculus monoclonal PF-06823859 γ1-chain), disulfide with human-Mus musculus monoclonal ... Immunoglobulin G1 [236-alanine,237-alanine,239-alanine,de-C-terminal-lysine], anti-(human interferon ... humanized monoclonal antibody (immunoglobulin gamma-1 with kappa light chains, IgG1kappa) directed against human
Efruxifermin is under investigation in clinical trial NCT06215716 (A Study Evaluating Efruxifermin in Subjects With Non-cirrhotic Nonalcoholic Steatohepatitis (Nash)/metabolic Dysfunction-associated Steatohepatitis (MASH) and Fibrosis).
Investigational
Matched Synonyms: … factor 21 (98-arginine,171-glycine,180-glutamic acid) (human mutant clone amg876) ... Immunoglobulin g (synthetic human constant domain fc fragment) fusion protein with fibroblast growth ... Immunoglobulin g1 (human .gamma.1-chain c-region c-terminal fragment) fusion protein with peptide linker …
Matched Description: … Non-cirrhotic Nonalcoholic Steatohepatitis (Nash)/metabolic Dysfunction-associated Steatohepatitis (MASH) and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).[label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation...
Approved
Vet approved
Matched Description: … Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation ... PGs contribute to inflammation and pain signalling. ... Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID). …
Matched Mixtures name: … Dfs 1.5%/ms 25%/menth 6%/cap 0.025% Pak ... DFS 75mg DR/MS 25%/MENTH 6%/CAP 0.025% PAK ... Calcipotriene 0.005% / Diclofenac Sodium 3% / Hyaluronic Acid Sodium Salt 2% / Niacinamide 2% …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... diclofenac and antiinfectives ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Up and Up Arthritis Pain Reliever ... Diclofenac Sodium 3% / Hyaluronic Acid Sodium Salt 2% / Niacinamide 4% ... FLECTOR TISSUGEL %1 FLASTER, 2 ADET …
Investigational
Matched Synonyms: … Human recombinant histidyl-t-RNA synthetase (residues 2-506) …
Investigational
Matched Synonyms: … Adeno-associated viral vector serotype 8 containing the human glucose-6-phosphatase gene ... Recombinant adeno-associated virus serotype 8 vector encoding human glucose-6-phosphatase-alpha ... Recombinant adeno-associated virus serotype 8 vector encoding human glucose-6-phosphatase-alpha (G6Pase …
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(HUMAN B7 HOMOLOG 3 PROTEIN) (HUMAN-MUS MUSCULUS MONOCLONAL MABX-9001A .GAMMA ... .1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL MABX-9001A .KAPPA. …
Insulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A2358, A2359, A2360, A44] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta...
Approved
Matched Synonyms: … Insulin,detemir,human
Matched Description: … tissues such as the liver, fat cells, and skeletal muscle. ... typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human ... along with slow systemic absorption from the injection site prolongs distribution of the hormone into tissues
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer.
Investigational
Withdrawn
Matched Synonyms: … Human monoclonal antibody targeting CC-chemokine ligand 2 (CNTO 888) …
Matched Description: … Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Synthetic Signal Peptide Of Human Mucin-1 (Amino Acids 1-21) …
HMI-102 is an investigational gene therapy designed to encode the phenylalanine-4-hydroxylase (PAH) gene, mutated in people with phenylketonuria.
Investigational
Matched Synonyms: … Recombinant adeno-associated viral vector serotype HSC expressing human phenylalanine hydroxylase …
Investigational
Matched Synonyms: … Expanded human allogeneic neural retinal progenitor cells extracted from neural retina …
Matched Name: … Expanded human allogeneic neural retinal progenitor cells extracted from neural retina …
Pemtumomab is a murine monoclonal antibody radiolabeled with Yttrium-90. It targets the mucin 1 (MUC1) protein.
Investigational
Matched Synonyms: … Murine MAb to polymorphic epithelial mucin, human milk fat globule 1 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
BGT-DTDS is an investigational gene therapy comprising an adeno-associated viral vector type 2 (AAV2) encoding the human SLC6A3 gene. It is under investigation for the treatment of dopamine transporter deficiency syndrome (DTDS).
Investigational
Matched Synonyms: … Adeno-associated viral vector serotype 2 containing the human SLC6A3 gene …
Matched Description: … investigational gene therapy comprising an adeno-associated viral vector type 2 (AAV2) encoding the human
Amatuximab has been used in trials studying the treatment and basic science of Mesothelioma, Ovarian Cancer, Ovarian Neoplasms, Pancreatic Cancer, and Mesothelioma, Malignant, among others.
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(mesothelin) (human-mouse monoclonal MORAb-009 heavy chain), disulfide with human-mouse …
Matched Description: … Cancer, Ovarian Neoplasms, Pancreatic Cancer, and Mesothelioma, Malignant, among others. ... Amatuximab has been used in trials studying the treatment and basic science of Mesothelioma, Ovarian …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Dapiclermin is a recombinant ciliary neurotrophic factor.
Investigational
Matched Synonyms: … 2-185-ciliary neurotrophic factor (17 -alanine,63-arginine) (human isoform axokine) ... 2-185-(17-alanine,63-agrinine)ciliary neurotrophic factor-(2,185)-peptide (human isoform axokine) …
Matched Categories: … Nerve Tissue Proteins ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(CYTOMEGALOVIRUS) (HUMAN MONOCLONAL EV2-7 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … with human-mus musculus monoclonal c4g7 .kappa. ... Immunoglobulin g1, anti-(ebolavirus glycoprotein) (human-mus musculus monoclonal c4g7 heavy chain), disulfide …
AAV9/MFSD8 is a gene therapy developed by Neurogene Inc. It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8. It was investigated for the treatment of neuronal ceroid lipofuscinosis type 7.
Investigational
Matched Synonyms: … MFSD8 gene for expression of active human major facilitator superfamily domain containing 8 ... An adeno-associated virus serotype 9 (AAV9) vector with engineered transgene encoding the human CLN7/ …
Matched Description: … CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8. ... It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human
Sotatercept is an activin signalling inhibitor. It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial hypertension...
Approved
Investigational
Matched Synonyms: … (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN ... (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN ... IMMUNOGLOBULIN G1 (SYNTHETIC HUMAN HEAVY CHAIN FC FRAGMENT), DIMER …
Matched Description: … [L50361] Sotatercept works to resolve the imbalance in activin–growth differentiation factor and BMP ... receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. ... It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ripertamab is under investigation in clinical trial NCT02772822 (A Study Comparing the Efficiency and Safety of S-chop(cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated Cd20(cluster of Differentiation Antigen 20)-positive DLBCL Patients).
Investigational
Matched Synonyms: … Immunoglobulin igg1, anti-(human cd20 antigen) (human-mus musculus monoclonal disulfide sct400 .gamma ... .1-chain), disulfide with human-mus musculus monoclonal sct400 .kappa. …
Matched Description: … Ripertamab is under investigation in clinical trial NCT02772822 (A Study Comparing the Efficiency and ... Safety of S-chop(cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated …
Investigational
Matched Synonyms: … Immunoglobulin g4 (224-proline,233-alanine,234-alanine), anti-(human dickkopf-1) (human-mus musculus ... monoclonal dkn-01 .gamma.4-chain), disulfide with human-mus musculus monoclonal dkn-01 .kappa. …
Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Europe in April 2003, teriparatide makes the first approved drug in...
Approved
Investigational
Matched Synonyms: … Teriparatide recombinant human
Matched Description: … Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. ... [A251395] It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. ... [A251395] First approved in the United States in November 2002 and in Europe in April 2003,[A251400] …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Calcium-Regulating Hormones and Agents ... Parathyroid Hormones and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Mirococept (APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and I/RI. It is a truncated form of the human Complement Receptor 1 (CR1) linked to a unique Prodaptin™ construct that regulates the over-production of complement at the cell surface, which occurs in inflammation. It consists...
Investigational
Matched Synonyms: … myristoylated recombinant SCR1-3 of human complement reseptor type I …
Matched Description: … APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and ... in recombinant bacteria and modified with a membrane-targeting amphiphilic peptide based on the naturally ... It is a truncated form of the human Complement Receptor 1 (CR1) linked to a unique Prodaptin™ construct …
Eptacog alfa pegol (activated) has been used in trials studying the prevention and treatment of Haemophilia A, Haemophilia B, Congenital Bleeding Disorder, Haemophilia B With Inhibitors, and Haemophilia A With Inhibitors.
Investigational
Matched Synonyms: … Activated Recombinant Human Factor VII, Long Acting …
Matched Description: … Eptacog alfa pegol (activated) has been used in trials studying the prevention and treatment of Haemophilia ... A, Haemophilia B, Congenital Bleeding Disorder, Haemophilia B With Inhibitors, and Haemophilia A With …
Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy to treat alpha-mannosidosis. Alpha-mannosidosis is a rare autosomal recessive lysosomal storage disorder. Patients with alpha-mannosidosis have a genetic mutation that causes a deficiency in the lysosomal enzyme alpha-mannosidase, which is an enzyme responsible for breaking down complex...
Approved
Investigational
Matched Synonyms: … Recombinant Human Alpha Mannosidase …
Matched Description: … impairment, intellectual disability, and respiratory dysfunction. ... to progressive neuromuscular and skeletal deterioration, such as skeletal abnormalities, motor function ... The resulting accumulation of sugars in the body leads to an array of clinical manifestations leading …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Recombinant Human Lysosomal alpha-Mannosidase …
Displaying drugs 876 - 900 of 1152 in total