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Displaying drugs 9176 - 9200 of 9442 in total
Halometasone
Experimental
Matched Iupac: … -trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one ... (1R,2S,8S,10S,11S,13R,14R,15S,17S)-4-chloro-1,8-difluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15 …
Deleobuvir
Deleobuvir is under investigation in clinical trial NCT01983566 (Effect of Food and Increased Gastric pH Value on Bioavailability of a Single Dose of BI 207127 in Healthy Caucasian and Japanese Subjects).
Investigational
Matched Iupac: … (2E)-3-(2-{1-[2-(5-bromopyrimidin-2-yl)-3-cyclopentyl-1-methyl-1H-indole-6-amido]cyclobutyl}-1-methyl ... -1H-1,3-benzodiazol-6-yl)prop-2-enoic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Lapaquistat
Lapaquistat is under investigation in clinical trial NCT00256178 (Efficacy of Lapaquistat Acetate and Simvastatin in Subjects With Primary Dyslipidemia.).
Investigational
Matched Iupac: … 2-(1-{2-[(3R,5S)-7-chloro-5-(2,3-dimethoxyphenyl)-1-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-1,2,3,5-tetrahydro …
Zotatifin
Zotatifin is under investigation in clinical trial NCT04092673 (Study of Eft226 in Subjects With Selected Advanced Solid Tumor Malignancies).
Investigational
Matched Iupac: … 4-[(2S,3R,4S,5S,6R)-4-[(dimethylamino)methyl]-2,3-dihydroxy-10,12-dimethoxy-5-phenyl-7-oxa-11-azatricyclo …
Co(III)-(Deuteroporphyrin IX)
Experimental
Matched Iupac: … lambda7-cobalt(7+) 5-(2-carboxyethyl)-9-(2-carboxylatoethyl)-4,10,15,20-tetramethyl-21,22,23,24-tetraazapentacyclo …
Phosphomethylphosphonic acid guanylate ester
Experimental
Matched Iupac: … ({[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy …
Sufugolix
Investigational
Matched Iupac: … 1-[4-(5-{[benzyl(methyl)amino]methyl}-1-[(2,6-difluorophenyl)methyl]-2,4-dioxo-3-phenyl-1H,2H,3H,4H-thieno …
Cefroxadine
Cefroxadine is an orally available cephalosporin antibiotic. As part of its drug class, it shares structural properties to cefalexin as well as its activity spectrum. It was used in Italy but has since been withdrawn.
Withdrawn
Matched Iupac: … (6R,7R)-7-[(2R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetamido]-3-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0 ... ]oct-2-ene-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
BMS-986142
BMS-986142 is under investigation in clinical trial NCT02880670 (Pharmacokinetics and Metabolism Study of Radiolabeled BMS-986142 in Healthy Male Subjects).
Investigational
Matched Iupac: … (2S)-6-fluoro-5-[3-(8-fluoro-1-methyl-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)-2-methylphenyl]-2- ... (2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide …
Rovatirelin
Rovatirelin is under investigation in clinical trial NCT01384435 (A Phase II Double Blind Comparative Study of KPS-0373 in Patients With Spinocerebellar Degeneration (SCD)).
Investigational
Matched Iupac: … (4S,5S)-5-methyl-N-[(2S)-1-[(2R)-2-methylpyrrolidin-1-yl]-1-oxo-3-(1,3-thiazol-4-yl)propan-2-yl]-2-oxo …
Pexiganan
Pexiganan is under investigation in clinical trial NCT01594762 (Pexiganan Versus Placebo Control for the Treatment of Mild Infections of Diabetic Foot Ulcers).
Investigational
Matched Iupac: … (2S)-6-amino-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-5-amino-1-{[(1S,2S)-1-{[(1S)-1-{[(1S)-5-amino-1-{[(1S ... )-5-amino-1-carbamoylpentyl]carbamoyl}pentyl]carbamoyl}-3-methylbutyl]carbamoyl}-2-methylbutyl]carbamoyl ... -2-[(2S)-6-amino-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-{2-[(2S,3S ... }pentyl]carbamoyl}-2-methylpropyl]carbamoyl}-2-phenylethyl]carbamoyl}ethyl]-2-{2-[(2S)-2-[(2S)-6-amino ... )-2-(2-aminoacetamido)-3-methylpentanamido]acetamido}hexanamido]-3-phenylpropanamido]-4-methylpentanamido …
GP-100 antigen
GP-100 antigen is under investigation in clinical trial NCT00006385 (Vaccine Therapy With or Without Biological Therapy in Treating Patients With Metastatic Melanoma).
Investigational
Olenasufligene relduparvovec
Olenasufligene relduparvovec is under investigation in clinical trial NCT03612869 (Study of aavrh10-h.sgsh Gene Therapy in Patients With Mucopolysaccharidosis Type IIIA (MPS IIIA)). It is an adeno-associated virus (AAV) vector that delivers a functional copy of the human SGSH gene.
Investigational
Matched Synonyms: … Dna (recombinant adeno-associated virus 2 vector lys-saf302 human n-sulfoglucosamine sulfohydrolase cdna-specifying …
L-Acetylleucine
Investigational
Matched Synonyms: … (s)-2-acetamido-4-methylpentanoic acid …
Matched Iupac: … (2S)-2-acetamido-4-methylpentanoic acid …
Matched Iupac: … (2S)-2-acetamido-4-methylpentanoic acid …
Serplulimab
Investigational
Bepranemab
Bepranemab is a recombinant humanized Igg4P monoclonal antibody directed against human Tau.
Investigational
Lactobacillus brevis
Investigational
AVR-RD-05
AVR-RD-05 is a gene therapy comprising genetically modified autologous stem cells transduced ex vivo with a lentiviral vector encoding the human iduronate-2-sulfatase (IDS) enzyme. It is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII).
Investigational
Matched Synonyms: … genetically modified autologous cell therapy intended for the stable provision of functional human iduronate-2- …
Matched Description: … modified autologous stem cells transduced _ex vivo_ with a lentiviral vector encoding the human iduronate-2- …
Matched Description: … modified autologous stem cells transduced _ex vivo_ with a lentiviral vector encoding the human iduronate-2- …
Frexalimab
Frexalimab is under investigation in clinical trial NCT06141486 (Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis).
Investigational
[2,4,6-Triisopropyl-Phenylsulfonyl-L-[3-Amidino-Phenylalanine]]-Piperazine-N'-Beta-Alanine
Experimental
Matched Iupac: … 3-[(2S)-3-[4-(3-aminopropanoyl)piperazin-1-yl]-3-oxo-2-[2,4,6-tris(propan-2-yl)benzenesulfonamido]propyl …
3-({4-[(1E)-3-morpholin-4-yl-3-oxoprop-1-en-1-yl]-2,3-bis(trifluoromethyl)phenyl}sulfanyl)aniline
Experimental
Matched Iupac: … (2E)-3-{4-[(3-aminophenyl)sulfanyl]-2,3-bis(trifluoromethyl)phenyl}-1-(morpholin-4-yl)prop-2-en-1-one …
N-({(3R,4R)-4-[(benzyloxy)methyl]pyrrolidin-3-yl}methyl)-N-(2-methylpropyl)benzenesulfonamide
Experimental
Matched Name: … N-({(3R,4R)-4-[(benzyloxy)methyl]pyrrolidin-3-yl}methyl)-N-(2-methylpropyl)benzenesulfonamide …
Matched Iupac: … N-{[(3R,4R)-4-[(benzyloxy)methyl]pyrrolidin-3-yl]methyl}-N-(2-methylpropyl)benzenesulfonamide …
Matched Iupac: … N-{[(3R,4R)-4-[(benzyloxy)methyl]pyrrolidin-3-yl]methyl}-N-(2-methylpropyl)benzenesulfonamide …
Vixarelimab
Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and Tolerability of KPL-716 in Reducing Pruritus in Prurigo Nodularis).
Investigational
Zimberelimab
Investigational
Displaying drugs 9176 - 9200 of 9442 in total