Displaying drugs 901 - 925 of 1388 in total
Maplirpacept
Maplirpacept is a recombinant fusion protein consisting of the CD47-binding domain of human signal regulatory protein alpha (SIRPa) linked to the IgG4 Fc region of human IgG.
Investigational
Matched Synonyms: … 1-118-Signal regulatory protein α (human) fusion protein with immunoglobulin G4 [128-proline] (human ... SIRPA-IGG4-FC FUSION PROTEIN TTI-622 …
Matched Description: … protein alpha (SIRPa) linked to the IgG4 Fc region of human IgG. ... Maplirpacept is a recombinant fusion protein consisting of the CD47-binding domain of human signal regulatory …
Matched Description: … protein alpha (SIRPa) linked to the IgG4 Fc region of human IgG. ... Maplirpacept is a recombinant fusion protein consisting of the CD47-binding domain of human signal regulatory …
Losartan
Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension. Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. When patients with ACE inhibitor associated coughs are switched to ARBs like losartan, they have an incidence of cough similar to placebo...
Approved
Matched Description: … available as losartan potassium oral tablets as well as a combination tablet of losartan potassium and ... [L7423,L7426] Patients taking losartan should have their renal function and potassium levels monitored …
Matched Mixtures name: … Losartan Potassium and Hydrochlorothiazide ... Losartan Potassium and Hydrochlorothiazide ... Losartan Potassium and Hydrochlorothiazide …
Matched Categories: … Angiotensin II receptor blockers (ARBs) and diuretics ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... losartan and diuretics ... losartan and amlodipine …
Matched Products: … COLIBS ... COZAAR PROTECT 50MG ... LORZAAR PROTECT 50MG …
Matched Mixtures name: … Losartan Potassium and Hydrochlorothiazide ... Losartan Potassium and Hydrochlorothiazide ... Losartan Potassium and Hydrochlorothiazide …
Matched Categories: … Angiotensin II receptor blockers (ARBs) and diuretics ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... losartan and diuretics ... losartan and amlodipine …
Matched Products: … COLIBS ... COZAAR PROTECT 50MG ... LORZAAR PROTECT 50MG …
Efavaleukin alfa
Efavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin G Fc domain by way of a G4S linker. It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With Steroid Refractory Chronic Graft Versus Host Disease).
Investigational
Matched Synonyms: … Fc il-2 mutein fusion protein (amg-592) ... protein with interleukin 2 (synthetic human mutein), dimer ... Immunoglobulin g1 (fc domain-containing fragment) fusion protein with peptide (synthetic linker) fusion …
Matched Description: … It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With ... Efavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin …
Matched Description: … It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With ... Efavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin …
Xylitol
Xylitol is a naturally occurring five-carbon sugar alcohol found in most plant material, including many fruits and vegetables. Xylitol-rich plant materials include birch and beechwood . It is widely used as a sugar substitute and in "sugar-free" food products. The effects of xylitol on dental caries have been widely studied,...
Experimental
Investigational
Matched Description: … a naturally occurring five-carbon sugar alcohol found in most plant material, including many fruits and ... gums and other oral care products to prevent tooth decay and dry mouth. ... Xylitol-rich plant materials include birch and beechwood [A22081]. …
Matched Categories: … Diet, Food, and Nutrition …
Matched Products: … Claon (toothpaste) …
Matched Categories: … Diet, Food, and Nutrition …
Matched Products: … Claon (toothpaste) …
AF-710B
Investigational
Matched Synonyms: … 1-(2,8-dimethyl-1-thia-3,8-diazaspiro(4.5)dec-3-yl)-3-(1h-indol-3-yl)propan-1-one ... 1-(2,8-Dimethyl-1-Thia-3,8-Diazaspiro[4.5]Dec-3-yl)-3-(1H-Indol-3-yl)Propan-1-one ... 1-propanone, 1-(2,8-dimethyl-1-thia-3,8-diazaspiro(4.5)dec-3-yl)-3-(1h-indol-3-yl)- …
Matched Iupac: … 1-{2,8-dimethyl-1-thia-3,8-diazaspiro[4.5]decan-3-yl}-3-(1H-indol-3-yl)propan-1-one …
Matched Iupac: … 1-{2,8-dimethyl-1-thia-3,8-diazaspiro[4.5]decan-3-yl}-3-(1H-indol-3-yl)propan-1-one …
JNJ-1802
Investigational
Matched Synonyms: … (4-chloro-2-methoxyphenyl)-2-((3-methoxy-5-(methylsulfonyl)phenyl)amino)-1-(5-(trifluoromethoxy)-1h-indol ... (4-chloro-2-methoxyphenyl)-2-((3-methoxy-5-(methylsulfonyl)phenyl)amino)-1-(5-(trifluoromethoxy)-1h-indol ... (4-chloro-2-methoxyphenyl)-2-((3-methoxy-5-(methylsulfonyl)phenyl)amino)-1-(5-(trifluoromethoxy)-1h-indol …
Matched Iupac: … -(4-chloro-2-methoxyphenyl)-2-[(3-methanesulfonyl-5-methoxyphenyl)amino]-1-[5-(trifluoromethoxy)-1H-indol …
Matched Iupac: … -(4-chloro-2-methoxyphenyl)-2-[(3-methanesulfonyl-5-methoxyphenyl)amino]-1-[5-(trifluoromethoxy)-1H-indol …
Anisindione
Anisindione is a synthetic anticoagulant and an indanedione derivative. Its anticoagulant action is mediated through the inhibition of the vitamin K-mediated gamma-carboxylation of precursor proteins that are critical in forming the formation of active procoagulation factors II, VII, IX, and X, as well as the anticoagulant proteins C and S,...
Approved
Matched Synonyms: … 2-(p-Methoxyphenyl)indane-1,3-dione ... 2-(4-Methoxyphenyl)-1H-indene-1,3(2H)-dione …
Matched Iupac: … 2-(4-methoxyphenyl)-2,3-dihydro-1H-indene-1,3-dione …
Matched Description: … as the anticoagulant proteins C and S, in the liver. ... Anisindione is a synthetic anticoagulant and an indanedione derivative. ... that are critical in forming the formation of active procoagulation factors II, VII, IX, and X, as well …
Matched Iupac: … 2-(4-methoxyphenyl)-2,3-dihydro-1H-indene-1,3-dione …
Matched Description: … as the anticoagulant proteins C and S, in the liver. ... Anisindione is a synthetic anticoagulant and an indanedione derivative. ... that are critical in forming the formation of active procoagulation factors II, VII, IX, and X, as well …
Saw palmetto
Saw palmetto is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Investigational
Matched Categories: … Herbs and Natural Products …
Matched Products: … PROSTESS UNO …
Matched Products: … PROSTESS UNO …
Carya tomentosa pollen
Carya tomentosa pollen is the pollen of the Carya tomentosa plant. Carya tomentosa pollen is mainly used in allergenic testing.
Approved
Matched Synonyms: … Carya alba pollen …
Corynebacterium diphtheriae CRM197 protein
Approved
Matched Synonyms: … Diphtheria CRM197 protein ... Corynebacterium diphtheriae CRM-197 protein …
Matched Name: … Corynebacterium diphtheriae CRM197 protein …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins …
Matched Name: … Corynebacterium diphtheriae CRM197 protein …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins …
CRS-207
Investigational
Matched Synonyms: … Live-attenuated Listeria monocytogenes actA/inlB/human mesothelin (hMeso) Strain hMeso38 …
Ilomastat
Ilomastat is a broad-spectrum matrix metalloproteinase inhibitor.
Experimental
Matched Synonyms: … (R)-N(SUP 1)-HYDROXY-N-((S)-2-INDOL-3-YL-1-(METHYLCARBAMOYL)ETHYL)-2-ISOBUTYLSUCCINAMIDE ... (S-(R*,S*))-N(SUP 4)-HYDROXY-N(SUP 1)-(1H-INDOL-3-YLMETHYL)-2-(METHYLAMINO)-2-OXOETHYL)-2-(2-METHYLOPROPYL …
Matched Iupac: … (2R)-N'-hydroxy-N-[(1S)-2-(1H-indol-3-yl)-1-(methylcarbamoyl)ethyl]-2-(2-methylpropyl)butanediamide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Protease Inhibitors …
Matched Iupac: … (2R)-N'-hydroxy-N-[(1S)-2-(1H-indol-3-yl)-1-(methylcarbamoyl)ethyl]-2-(2-methylpropyl)butanediamide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Protease Inhibitors …
SEphB4-HSA
SEphB4-HSA is under investigation in clinical trial NCT02495896 (Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors).
Investigational
Matched Synonyms: … RECOMBINANT EPHB4-HSA FUSION PROTEIN …
Matched Description: … SEphB4-HSA is under investigation in clinical trial NCT02495896 (Recombinant EphB4-HSA Fusion Protein …
Matched Description: … SEphB4-HSA is under investigation in clinical trial NCT02495896 (Recombinant EphB4-HSA Fusion Protein …
Axalimogene filolisbac
Axalimogene filolisbac is under investigation in clinical trial NCT02853604 (Study of ADXS11-001 in Subjects With High Risk Locally Advanced Cervical Cancer).
Investigational
Matched Synonyms: … Live, attenuated listeria monocytogenes bacteria, expressing human papilloma virus type 16-e7 tumor antigen …
Cemsidomide
Investigational
Matched Synonyms: … (3s)-3-(6-((4-(morpholin-4-ylmethyl)phenyl)methyl)-2-oxobenzo(cd)indol-1-yl)piperidine-2,6-dione ... 2,6-piperidinedione, 3-(6-((4-(4-morpholinylmethyl)phenyl)methyl)-2-oxobenz(cd)indol-1(2h)-yl)-, (3s) …
Influenza B virus Yamagata lineage haemagglutinin, recombinant
Approved
Matched Synonyms: … Recombinant haemagglutinin protein-strain B (Yamagata) …
Ontorpacept
Investigational
Matched Synonyms: … 1-118-signal regulatory protein .alpha. ... (human) fusion protein with immunoglobulin g1 (human fc fragment), dimer …
Serotonin
For temporary relief of nervousness, anxiety, mood swings, joint pains, weakness, drowsiness, itching and lethargy. Not evaluated by the FDA, homeopathic product.
Investigational
Nutraceutical
Matched Synonyms: … 3-(2-Aminoethyl)-1H-indol-5-ol …
Matched Iupac: … 3-(2-aminoethyl)-1H-indol-5-ol …
Matched Description: … For temporary relief of nervousness, anxiety, mood swings, joint pains, weakness, drowsiness, itching and …
Matched Categories: … Indoles …
Matched Iupac: … 3-(2-aminoethyl)-1H-indol-5-ol …
Matched Description: … For temporary relief of nervousness, anxiety, mood swings, joint pains, weakness, drowsiness, itching and …
Matched Categories: … Indoles …
Iptacopan
Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor B. Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and subsequently C5 convertase. This is...
Approved
Investigational
Matched Synonyms: … 4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl) benzoic acid ... BENZOIC ACID, 4-((2S,4S)-4-ETHOXY-1-((5-METHOXY-7-METHYL-1H-INDOL-4-YL)METHYL)-2-PIPERIDINYL)- …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid …
Matched Description: … that normally anchor 2 membrane proteins, CD55 and CD59, that protect blood cells against the alternative ... C3 convertase and subsequently C5 convertase. ... benefit of targeting factor B, which only affect the alternative complement pathway, leaving the classic and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid …
Matched Description: … that normally anchor 2 membrane proteins, CD55 and CD59, that protect blood cells against the alternative ... C3 convertase and subsequently C5 convertase. ... benefit of targeting factor B, which only affect the alternative complement pathway, leaving the classic and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
BMS-986251
BMS-986251 is under investigation in clinical trial NCT03329885 (A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Participants and Patients With Average to Very Serious Psoriasis).
Investigational
Matched Synonyms: … (3AR,9BR)-9B-((4-FLUOROPHENYL)SULFONYL)-7-(PERFLUOROPROPAN-2-YL)-2,3,3A,4,5,9B-HEXAHYDRO-1H-BENZO(E)INDOLE …
Matched Description: … NCT03329885 (A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Participants and …
Matched Description: … NCT03329885 (A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Participants and …
ATM-3507
Investigational
Matched Synonyms: … (3-((2,3-dimethyl-1-(3-(4-methylpiperazin-1-yl)propyl)-1h-indol-5-yl)oxy)phenyl)(4-(4-fluorophenethyl ... Methanone, (3-((2,3-dimethyl-1-(3-(4-methyl-1-piperazinyl)propyl)-1h-indol-5-yl)oxy)phenyl)(4-(2-(4-fluorophenyl …
Matched Iupac: … fluorophenyl)ethyl]piperazine-1-carbonyl}phenoxy)-2,3-dimethyl-1-[3-(4-methylpiperazin-1-yl)propyl]-1H-indole …
Matched Iupac: … fluorophenyl)ethyl]piperazine-1-carbonyl}phenoxy)-2,3-dimethyl-1-[3-(4-methylpiperazin-1-yl)propyl]-1H-indole …
indane-5-sulfonamide
Experimental
Matched Name: … indane-5-sulfonamide …
Matched Iupac: … 2,3-dihydro-1H-indene-5-sulfonamide …
Matched Iupac: … 2,3-dihydro-1H-indene-5-sulfonamide …
EDI-200
EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the human receptor binding domain of ectodysplasin-A1.
Investigational
Matched Synonyms: … FC:EDA-A1 FUSION PROTEIN ... HUMAN IMMUNOGLOBULIN G1 CONSTANT REGION - HUMAN ECTODYSPLASIN-A1 RECEPTOR-BINDING DOMAIN FUSION PROTEIN …
Matched Description: … EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins ... Blood Proteins ... Membrane Proteins …
Matched Description: … EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins ... Blood Proteins ... Membrane Proteins …
Zanthoxylum clava-herculis whole
Zanthoxylum clava-herculis whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Zanthoxylum Clava-herculis …
Matched Name: … Zanthoxylum clava-herculis whole …
Matched Description: … Zanthoxylum clava-herculis whole is a plant/plant extract used in some OTC (over-the-counter) products …
Matched Name: … Zanthoxylum clava-herculis whole …
Matched Description: … Zanthoxylum clava-herculis whole is a plant/plant extract used in some OTC (over-the-counter) products …
Alpha-1-proteinase inhibitor
Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.
Approved
Matched Synonyms: … .-1 protease inhibitor ... Protease inhibitor wap4 ... Alpha-1 protease inhibitor …
Matched Description: … inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes ... Proteins ... Blood Proteins …
Matched Description: … inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes ... Proteins ... Blood Proteins …
Displaying drugs 901 - 925 of 1388 in total