Displaying drugs 926 - 950 of 2911 in total
Diethyl phosphonate
Experimental
Matched Synonyms: … Diethyl acid phosphite ... Phosphonic acid diethyl ester ... Phosphorous acid, diethyl ester …
L-2,4-diaminobutyric acid
Experimental
Matched Synonyms: … (S)-2,4-Diaminobutanoic acid ... L-diaminobutyric acid ... L-2,4-diaminobutanoic acid …
Matched Name: … L-2,4-diaminobutyric acid …
Matched Iupac: … (2S)-2,4-diaminobutanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids …
Matched Name: … L-2,4-diaminobutyric acid …
Matched Iupac: … (2S)-2,4-diaminobutanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids …
Amiloride
A pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with...
Approved
Matched Description: … Negative potential reduces secretion of potassium and hydrogen ions. ... negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and ... (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705) …
Matched Mixtures name: … Amiloride Hydrochloride and Hydrochlorothiazide ... Amiloride Hydrochloride and Hydrochlorothiazide ... Amiloride Hydrochloride and Hydrochlorothiazide …
Matched Salts name: … Amiloride hydrochloride ... Amiloride hydrochloride dihydrate …
Matched Categories: … Acid Sensing Ion Channel Blockers …
Matched Products: … Amiloride Hydrochloride ... Amiloride Hydrocloride ... Amiloride Hydrochloride Tablets, USP …
Matched Mixtures name: … Amiloride Hydrochloride and Hydrochlorothiazide ... Amiloride Hydrochloride and Hydrochlorothiazide ... Amiloride Hydrochloride and Hydrochlorothiazide …
Matched Salts name: … Amiloride hydrochloride ... Amiloride hydrochloride dihydrate …
Matched Categories: … Acid Sensing Ion Channel Blockers …
Matched Products: … Amiloride Hydrochloride ... Amiloride Hydrocloride ... Amiloride Hydrochloride Tablets, USP …
Bupivacaine
Bupivacaine is a widely used local anesthetic agent.
Approved
Investigational
Matched Mixtures name: … Bupivacaine Hydrochloride and Epinephrine ... Bupivacaine Hydrochloride and Epinephrine ... Bupivacaine Hydrochloride and Epinephrine …
Matched Salts name: … Bupivacaine hydrochloride ... Bupivacaine hydrochloride anhydrous …
Matched Categories: … bupivacaine and meloxicam …
Matched Products: … BUVICAINE %0.5 ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON,1 ADET ... MARCAINE % 0.5 ENJEKSİYONLUK SOLÜSYON İÇEREN FLAKON, 20 ML ... BUVASIN 5 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET …
Matched Salts name: … Bupivacaine hydrochloride ... Bupivacaine hydrochloride anhydrous …
Matched Categories: … bupivacaine and meloxicam …
Matched Products: … BUVICAINE %0.5 ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON,1 ADET ... MARCAINE % 0.5 ENJEKSİYONLUK SOLÜSYON İÇEREN FLAKON, 20 ML ... BUVASIN 5 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET …
Ferrous cation
Experimental
Matched Products: … FERRO GLUCONATO EG ... FERRO GLUCONATO KALISKIN ... FERRO GLUCONATO SO.SE.PHARM …
6-hydroxynorleucine
Experimental
Matched Synonyms: … 2-Amino-6-hydroxycaproic acid ... alpha-Amino-epsilon-hydroxycaproic acid …
Matched Iupac: … (2S)-2-amino-6-hydroxyhexanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Matched Iupac: … (2S)-2-amino-6-hydroxyhexanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Eprodisate
Eprodisate slows the decline of renal function in AA amyloidosis.
Investigational
Matched Synonyms: … 1,3-propanedisulfonic acid ... Propane-1,3-disulfonic acid …
Matched Iupac: … propane-1,3-disulfonic acid …
Matched Categories: … Acids ... Sulfur Acids ... Acids, Noncarboxylic …
Matched Iupac: … propane-1,3-disulfonic acid …
Matched Categories: … Acids ... Sulfur Acids ... Acids, Noncarboxylic …
Monoctanoin
Monoctanoin is used to dissolve cholesterol gallstones.
Experimental
Matched Synonyms: … Caprylic acid α-monoglyceride ... Octanoic acid 1-monoglyceride …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids …
Ornithine
Produced during the urea cycle, ornithine is an amino acid produced from the splitting off of urea from arginine. L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine.
Approved
Nutraceutical
Matched Synonyms: … (S)-2,5-Diaminopentanoic acid ... (S)-2,5-diaminovaleric acid ... (S)-α,δ-diaminovaleric acid …
Matched Iupac: … (2S)-2,5-diaminopentanoic acid …
Matched Description: … Produced during the urea cycle, ornithine is an amino acid produced from the splitting off of urea from ... L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine …
Matched Mixtures name: … PRIMENE 10% AMINO ACID INTRAVENOUS INFUSION …
Matched Salts name: … Ornithine hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Amino Acids ... Amino Acids, Basic …
Matched Iupac: … (2S)-2,5-diaminopentanoic acid …
Matched Description: … Produced during the urea cycle, ornithine is an amino acid produced from the splitting off of urea from ... L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine …
Matched Mixtures name: … PRIMENE 10% AMINO ACID INTRAVENOUS INFUSION …
Matched Salts name: … Ornithine hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Amino Acids ... Amino Acids, Basic …
Probenecid
The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
Approved
Investigational
Matched Synonyms: … Probenecid acid ... 4-((Dipropylamino)sulfonyl)benzoic acid ... p-(Dipropylsulfamoyl)benzoic acid …
Matched Iupac: … 4-(dipropylsulfamoyl)benzoic acid …
Matched Description: … It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. ... Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal …
Matched Mixtures name: … Pro Biosan Kit ... Probenecid and Colchicine ... Probenecid and Colchicine …
Matched Categories: … Preparations Increasing Uric Acid Excretion ... colchicine and probenecid ... Genito Urinary System and Sex Hormones ... Preparations With No Effect on Uric Acid Metabolism ... Gynecological Antiinfectives and Antiseptics …
Matched Iupac: … 4-(dipropylsulfamoyl)benzoic acid …
Matched Description: … It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. ... Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal …
Matched Mixtures name: … Pro Biosan Kit ... Probenecid and Colchicine ... Probenecid and Colchicine …
Matched Categories: … Preparations Increasing Uric Acid Excretion ... colchicine and probenecid ... Genito Urinary System and Sex Hormones ... Preparations With No Effect on Uric Acid Metabolism ... Gynecological Antiinfectives and Antiseptics …
Dimethyl fumarate
Dimethyl fumarate is an agent indicated for the treatment of relapsing forms of multiple sclerosis.[A253942,L43752] The mechanism of action of dimethyl fumarate in multiple sclerosis is not well understood. It is thought to involve dimethyl fumarate degradation to its active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor...
Approved
Investigational
Matched Synonyms: … (E)-But-2-enedioic acid dimethyl ester ... Fumaric acid, dimethyl ester ... trans-Butenedioic acid dimethyl ester …
Matched Description: … agent for multiple sclerosis approved by the FDA, following [fingolimod] and [teriflunomide]. ... [L43752] Dimethyl fumarate is marketed under the brand name Tecfidera, and it was the third oral disease-modifying …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Products: … DIMETILFUMARATO BIOCON …
Matched Description: … agent for multiple sclerosis approved by the FDA, following [fingolimod] and [teriflunomide]. ... [L43752] Dimethyl fumarate is marketed under the brand name Tecfidera, and it was the third oral disease-modifying …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Products: … DIMETILFUMARATO BIOCON …
Methyl nonanoate
Experimental
Matched Synonyms: … Methyl ester nonanoic acid ... Pelargonic acid methyl ester …
Lonidamine
Lonidamine (LND) is a drug that interferes with energy metabolism of cancer cells, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK). In such way LND could impair energy-requiring processes, as recovery from potentially lethal damage, induced by radiation treatment and by some cytotoxic drugs.
Investigational
Matched Synonyms: … diclondazolic acid ... 1-(2,4-dichlorbenzyl)-indazole-3-carboxylic acid …
Matched Iupac: … 1-[(2,4-dichlorophenyl)methyl]-1H-indazole-3-carboxylic acid …
Matched Description: … energy-requiring processes, as recovery from potentially lethal damage, induced by radiation treatment and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 1-[(2,4-dichlorophenyl)methyl]-1H-indazole-3-carboxylic acid …
Matched Description: … energy-requiring processes, as recovery from potentially lethal damage, induced by radiation treatment and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Aconiazide
Investigational
Matched Synonyms: … Isonicotinic acid (2-(carboxymethoxy)benzylidene)hydrazide ... Isonicotinic acid (o-(carboxymethoxy)benzylidene)hydrazide …
Matched Iupac: … 2-{2-[(E)-{[(pyridin-4-yl)formamido]imino}methyl]phenoxy}acetic acid …
Matched Categories: … Acids, Heterocyclic ... Isonicotinic Acids …
Matched Iupac: … 2-{2-[(E)-{[(pyridin-4-yl)formamido]imino}methyl]phenoxy}acetic acid …
Matched Categories: … Acids, Heterocyclic ... Isonicotinic Acids …
D-Erythro-2,3-diaminobutyric acid
Experimental
Matched Synonyms: … (2R,3R)-2,3-Diaminobutanoic acid …
Matched Name: … D-Erythro-2,3-diaminobutyric acid …
Matched Iupac: … (2R,3R)-2,3-diaminobutanoic acid …
Matched Name: … D-Erythro-2,3-diaminobutyric acid …
Matched Iupac: … (2R,3R)-2,3-diaminobutanoic acid …
Ceftiofur
Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary medicine. It is marketed by pharmaceutical company Zoetis as Excenel, and is the active ingredient in that company's Specramast LC (lactating cow formula) product. It is resistant to hydrolysis by beta-lactamase, and has activity...
Vet approved
Matched Synonyms: … Ceftiofur crystalline free acid …
Matched Iupac: … acetamido]-3-[(furan-2-carbonylsulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … It is resistant to hydrolysis by beta-lactamase, and has activity against both Gram-positive and Gram-negative ... Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary ... It is marketed by pharmaceutical company Zoetis as Excenel, and is the active ingredient in that company's …
Matched Salts name: … Ceftiofur hydrochloride …
Matched Categories: … Thiazines …
Matched Iupac: … acetamido]-3-[(furan-2-carbonylsulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … It is resistant to hydrolysis by beta-lactamase, and has activity against both Gram-positive and Gram-negative ... Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary ... It is marketed by pharmaceutical company Zoetis as Excenel, and is the active ingredient in that company's …
Matched Salts name: … Ceftiofur hydrochloride …
Matched Categories: … Thiazines …
Phenibut
Experimental
Matched Synonyms: … 4-amino-3-phenylbutyric acid …
Matched Iupac: … 4-amino-3-phenylbutanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hypnotics and Sedatives ... Psychostimulants, Agents Used for ADHD and Nootropics ... Amino Acids ... Acids, Acyclic …
Matched Iupac: … 4-amino-3-phenylbutanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hypnotics and Sedatives ... Psychostimulants, Agents Used for ADHD and Nootropics ... Amino Acids ... Acids, Acyclic …
Agatolimod
Agatolimod is under investigation in clinical trial NCT00471471 (Vaccine Therapy in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery).
Investigational
Matched Synonyms: … PF-3512676 free acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Florilglutamic acid F-18
Florilglutamic acid F-18 is under investigation in clinical trial NCT02370563 (PET Imaging of Intracranial Cancers With 18F-FSPG).
Investigational
Matched Synonyms: … [F18] Florilglutamic Acid …
Matched Name: … Florilglutamic acid F-18 …
Matched Iupac: … (2S,4S)-2-amino-4-[3-(¹⁸F)fluoropropyl]pentanedioic acid …
Matched Description: … Florilglutamic acid F-18 is under investigation in clinical trial NCT02370563 (PET Imaging of Intracranial …
Matched Name: … Florilglutamic acid F-18 …
Matched Iupac: … (2S,4S)-2-amino-4-[3-(¹⁸F)fluoropropyl]pentanedioic acid …
Matched Description: … Florilglutamic acid F-18 is under investigation in clinical trial NCT02370563 (PET Imaging of Intracranial …
Foslinanib
Foslinanib is under investigation in clinical trial NCT03600233 (Study of CVM-1118 for Patients With Advanced Neuroendocrine Tumors).
Investigational
Matched Synonyms: … Trx-818 free acid …
Matched Iupac: … {[2-(3-fluorophenyl)-6-methoxy-4-oxo-1,4-dihydroquinolin-5-yl]oxy}phosphonic acid …
Matched Iupac: … {[2-(3-fluorophenyl)-6-methoxy-4-oxo-1,4-dihydroquinolin-5-yl]oxy}phosphonic acid …
Imidazole-4-carboxylic acid
Imidazole-4-carboxylic acid is under investigation in clinical trial NCT00583895 (Safety and Efficacy Study of Imcooh Cream in Patients Suffering From Moderate Atopic Dermatitis).
Investigational
Matched Synonyms: … 4-Imidazolecarboxylic acid …
Matched Name: … Imidazole-4-carboxylic acid …
Matched Iupac: … 1H-imidazole-4-carboxylic acid …
Matched Description: … Imidazole-4-carboxylic acid is under investigation in clinical trial NCT00583895 (Safety and Efficacy …
Matched Name: … Imidazole-4-carboxylic acid …
Matched Iupac: … 1H-imidazole-4-carboxylic acid …
Matched Description: … Imidazole-4-carboxylic acid is under investigation in clinical trial NCT00583895 (Safety and Efficacy …
Nedosiran
Nedosiran is an RNA interference targeting hepatic lactate dehydrogenase, the enzyme responsible for the conversion of glyoxylate to oxalate. Oxalate, particularly calcium oxalate, precipitation is the main cause of kidney stones formation; therefore, blocking the production of oxalate can help alleviate renal symptoms. Nedosiran was approved by the FDA on...
Approved
Investigational
Matched Synonyms: … DCR-PHXC free acid …
Matched Description: … older and adults with primary hyperoxaluria type 1 (PH1) and relatively preserved kidney function. ... sup>, 2023, under the brand name RIVFLOZA to lower urinary oxalate levels in children 9 years of age and ... This approval is based on the favorable results from the pivotal phase 2 PHYOXTM2 and interim …
Matched Description: … older and adults with primary hyperoxaluria type 1 (PH1) and relatively preserved kidney function. ... sup>, 2023, under the brand name RIVFLOZA to lower urinary oxalate levels in children 9 years of age and ... This approval is based on the favorable results from the pivotal phase 2 PHYOXTM2 and interim …
Flurbiprofen
Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Synonyms: … (±)-2-fluoro-α-methyl-4-biphenylacetic acid ... 3-fluoro-4-phenylhydratropic acid ... 2-(2-fluorobiphenyl-4-yl)propanoic acid …
Matched Iupac: … 2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoic acid …
Matched Description: … Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic ... and analgesic activity. ... Flurbiprofen is structurally and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Acids, Acyclic ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain ... Carboxylic Acids …
Matched Products: … Strepsils MaxPro Honey and Lemon lozenges 8.75mg …
Matched Iupac: … 2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoic acid …
Matched Description: … Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic ... and analgesic activity. ... Flurbiprofen is structurally and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Acids, Acyclic ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain ... Carboxylic Acids …
Matched Products: … Strepsils MaxPro Honey and Lemon lozenges 8.75mg …
Trimethobenzamide
Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric...
Approved
Investigational
Matched Description: … Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. …
Matched Salts name: … Trimethobenzamide hydrochloride …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Products: … Trimethobenzamide Hydrochloride ... Trimethobenzamide hydrochloride ... Trimethobenzamide Hydorchloride …
Matched Salts name: … Trimethobenzamide hydrochloride …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Products: … Trimethobenzamide Hydrochloride ... Trimethobenzamide hydrochloride ... Trimethobenzamide Hydorchloride …
TPMPA
TPMPA ((1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid) is a selective antagonist of GABAC receptors (also known as GABA-ρ or GABAA-ρ receptors). GABAC receptors are found primarily in the retina, although they may be present in other tissues, including the hippocampus, spinal cord, superior colliculus, pituitary and the gut.[A245308,A245313] TPMPA is used as a pharmacological...
Experimental
Matched Synonyms: … (1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid ... P-Methyl-P-(1,2,3,6-tetrahydro-4-pyridinyl)phosphinic acid ... Phosphinic acid, P-methyl-P-(1,2,3,6-tetrahydro-4-pyridinyl)- …
Matched Iupac: … methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid …
Matched Description: … be present in other tissues, including the hippocampus, spinal cord, superior colliculus, pituitary and ... TPMPA ((1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid) is a selective antagonist of GABA …
Matched Iupac: … methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid …
Matched Description: … be present in other tissues, including the hippocampus, spinal cord, superior colliculus, pituitary and ... TPMPA ((1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid) is a selective antagonist of GABA …
Displaying drugs 926 - 950 of 2911 in total