Displaying drugs 9476 - 9500 of 14740 in total
Phenserine
Phenserine is under development by Axonyx, a US biopharmaceutical company that focuses on treatments for dementia. Phenserine is a next generation acetylcholinesterase (AChE) inhibitor indicated for the treatment of AD. Unlike currently marketed AChE inhibitors, it has a dual mechanism of action that also includes anti-amyloid activity, which may confer...
Investigational
Zidovudine monophosphate
Experimental
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Farletuzumab
Farletuzumab (MORAb-003) is a fully humanized monoclonal antibody against the folate receptor alpha, for the potential treatment of epithelial ovarian cancer.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Calcitonin gene-related peptide
A 37-amino acid peptide derived from the calcitonin gene. It occurs as a result of alternative processing of mRNA from the calcitonin gene. The neuropeptide is widely distributed in the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes...
Investigational
Matched Description: … The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes ... The neuropeptide is widely distributed in the brain, gut, perivascular nerves, and other tissue. ... profile that could make it an ideal anti-asthmatic drug candidate with bronchodilatory, bronchoprotecting and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Zalutumumab
Zalutumumab is a fully human IgG1 monoclonal antibody designed to bind with selectivity to the epidermal growth factor receptor (EGFR). Zalutumumab has been investigated for the treatment of Squamous Cell Cancer and Head and Neck Cancer.
Investigational
Matched Description: … Zalutumumab has been investigated for the treatment of Squamous Cell Cancer and Head and Neck Cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Abicipar Pegol
Abicipar Pegol has been used in trials studying the treatment of Macular Edema and Macular Degeneration.
Investigational
Matched Description: … Abicipar Pegol has been used in trials studying the treatment of Macular Edema and Macular Degeneration …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Imgatuzumab
Imgatuzumab is under investigation in clinical trial NCT01326000 (A Study of RO5083945 in Combination With FOLFIRI Versus FOLFIRI Plus Cetuximab or FOLFIRI Alone as Second Line Treatment in Patients With Metastatic Colorectal Cancer).
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Albuvirtide
Albuvirtide is under investigation in clinical trial NCT03719664 (Albuvirtide and 3BNC117 as Long-Acting Maintenance Therapy in Virologically Suppressed Subjects).
Investigational
Matched Description: … Albuvirtide is under investigation in clinical trial NCT03719664 (Albuvirtide and 3BNC117 as Long-Acting …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tallimustine
Tallimustine, a benzoyl mustard derivative of distamycin A, is an alkylating agent that binds to the minor groove of DNA.[A182036,A182039] It's association with severe myelotoxicity lead to the end of its development in favour of α-halogenoacrylamide derivatives such as brostallicin, which have a favourable cytotoxicity/myelotoxicity ratio.[A182039,A182045] Newer generations of DNA...
Experimental
Matched Categories: … Amino Acids, Peptides, and Proteins …
24-Homo-1,25-dihydroxyvitamin D3
24-Homo-1,25-dihydroxyvitamin D3 is a novel vitamin D analogue.
Experimental
Matched Categories: … Vitamin D and Analogues …
Orelabrutinib
Orelabrutinib is under investigation in clinical trial NCT04305197 (A Study of ICP-022 in Patients With Systemic Lupus Erythematosus (SLE)).
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Oregovomab
Oregovomab is a murine monoclonal antibody that attaches to the tumor-associated antigen CA125.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
LX1031
LX1031 is an orally-dosed drug candidate for irritable bowel syndrome and other gastrointestinal disorders. LX1031 was generated by Lexicon medicinal chemists, and its target was internally identified as a key control point for the regulation of peripheral serotonin levels. LX1031 is designed to act locally in the gastrointestinal tract by...
Investigational
Matched Description: … LX1031 is an orally-dosed drug candidate for irritable bowel syndrome and other gastrointestinal disorders ... LX1031 was generated by Lexicon medicinal chemists, and its target was internally identified as a key …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
AZD-8848
AZD-8848 is under investigation in clinical trial NCT01818869 (To Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Doses AZD8848 in Healthy Subjects).
Investigational
Matched Description: … under investigation in clinical trial NCT01818869 (To Assess the Safety, Tolerability, Pharmacokinetics and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Gimsilumab
Gimsilumab is under investigation in clinical trial NCT01357759 (Safety and Tolerability of MORAb-022 in Healthy and Rheumatoid Arthritis Subjects).
Investigational
Matched Description: … in Healthy and Rheumatoid Arthritis Subjects). ... Gimsilumab is under investigation in clinical trial NCT01357759 (Safety and Tolerability of MORAb-022 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Avdoralimab
Avdoralimab is under investigation in clinical trial NCT04333914 (Prospective Study in Patients With Advanced or Metastatic Cancer and Sars-cov-2 Infection).
Investigational
Matched Description: … investigation in clinical trial NCT04333914 (Prospective Study in Patients With Advanced or Metastatic Cancer and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
5,6-dihydro-5-azacytidine
Investigational
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Sonelokimab
Sonelokimab is under investigation in clinical trial NCT06411379 (Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa).
Investigational
Matched Description: … Sonelokimab is under investigation in clinical trial NCT06411379 (Study to Evaluate the Efficacy and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Genipin
Genipin is under investigation in clinical trial NCT05755750 (Intratendinous Genipin Injection in Horses With Tendon Injuries).
Investigational
Matched Categories: … Cholagogues and Choleretics …
Displaying drugs 9476 - 9500 of 14740 in total