Sulfathiourea
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Sulfathiourea
- DrugBank Accession Number
- DB13699
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 231.29
Monoisotopic: 231.01361889 - Chemical Formula
- C7H9N3O2S2
- Synonyms
- 1-sulfanilyl-2-thiourea
- 4-amino-N-(aminothioxomethyl)benzenesulfonamide
- p-aminobenzenesulfonylthiourea
- p-aminophenylsulfonylthiourea
- Sulfathiocarbamide
- Sulfathiourea
- Sulfathiourée
- Sulfatiourea
- Sulphathiourea
- External IDs
- R.P. 2255
- RP 2255
- RP-2255
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAcarbose The therapeutic efficacy of Acarbose can be increased when used in combination with Sulfathiourea. Acetohexamide The therapeutic efficacy of Acetohexamide can be increased when used in combination with Sulfathiourea. Albiglutide The therapeutic efficacy of Albiglutide can be increased when used in combination with Sulfathiourea. Alogliptin The therapeutic efficacy of Alogliptin can be increased when used in combination with Sulfathiourea. Benzylpenicillin Sulfathiourea may decrease the excretion rate of Benzylpenicillin which could result in a higher serum level. - Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- International/Other Brands
- Badional / Fontamide
Categories
- ATC Codes
- J01EB08 — Sulfathiourea
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as aminobenzenesulfonamides. These are organic compounds containing a benzenesulfonamide moiety with an amine group attached to the benzene ring.
- Kingdom
- Organic compounds
- Super Class
- Benzenoids
- Class
- Benzene and substituted derivatives
- Sub Class
- Benzenesulfonamides
- Direct Parent
- Aminobenzenesulfonamides
- Alternative Parents
- Benzenesulfonyl compounds / Aniline and substituted anilines / Organosulfonic acids and derivatives / Aminosulfonyl compounds / Primary amines / Organopnictogen compounds / Organic oxides / Hydrocarbon derivatives
- Substituents
- Amine / Aminobenzenesulfonamide / Aminosulfonyl compound / Aniline or substituted anilines / Aromatic homomonocyclic compound / Benzenesulfonyl group / Hydrocarbon derivative / Organic nitrogen compound / Organic oxide / Organic oxygen compound
- Molecular Framework
- Aromatic homomonocyclic compounds
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- MXF9G4I1V5
- CAS number
- 515-49-1
- InChI Key
- UEMLYRZWLVXWRU-UHFFFAOYSA-N
- InChI
- InChI=1S/C7H9N3O2S2/c8-5-1-3-6(4-2-5)14(11,12)10-7(9)13/h1-4H,8H2,(H3,9,10,13)
- IUPAC Name
- (4-aminobenzenesulfonyl)thiourea
- SMILES
- NC(=S)NS(=O)(=O)C1=CC=C(N)C=C1
References
- General References
- Not Available
- External Links
- KEGG Drug
- D07239
- ChemSpider
- 2272143
- ChEBI
- 131723
- ChEMBL
- CHEMBL2107489
- ZINC
- ZINC000003873929
- Wikipedia
- Sulfathiourea
Clinical Trials
- Clinical Trials
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Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.344 mg/mL ALOGPS logP 0.2 ALOGPS logP 0.3 Chemaxon logS -2.8 ALOGPS pKa (Strongest Acidic) 6.13 Chemaxon pKa (Strongest Basic) 2.25 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 98.21 Å2 Chemaxon Rotatable Bond Count 1 Chemaxon Refractivity 59.15 m3·mol-1 Chemaxon Polarizability 21.75 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS splash10-0a4i-0900000000-b0627634b9551aeeaf59 Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS splash10-0002-0900000000-03ee00922cf89336c556 Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS splash10-0a4l-5900000000-4198eb5f7d5ae1d228e7 Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS splash10-00di-0900000000-51b6115c658c4cf6db05 Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS splash10-014l-9000000000-afa6c7e944fef397b7eb Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS splash10-054o-9210000000-a958da0de8d8d79ff9d2 Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 154.9317577 predictedDarkChem Lite v0.1.0 [M-H]- 148.21706 predictedDeepCCS 1.0 (2019) [M+H]+ 156.1382577 predictedDarkChem Lite v0.1.0 [M+H]+ 150.61263 predictedDeepCCS 1.0 (2019) [M+Na]+ 155.5075577 predictedDarkChem Lite v0.1.0 [M+Na]+ 156.6124 predictedDeepCCS 1.0 (2019)
Drug created at June 23, 2017 20:46 / Updated at February 21, 2021 18:54