This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Sulfathiourea
- DrugBank Accession Number
- DB13699
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Sulfathiourea (DB13699)
- Weight
- Average: 231.29
Monoisotopic: 231.01361889 - Chemical Formula
- C7H9N3O2S2
- Synonyms
- 1-sulfanilyl-2-thiourea
- 4-amino-N-(aminothioxomethyl)benzenesulfonamide
- p-aminobenzenesulfonylthiourea
- p-aminophenylsulfonylthiourea
- Sulfathiocarbamide
- Sulfathiourea
- Sulfathiourée
- Sulfatiourea
- Sulphathiourea
- External IDs
- R.P. 2255
- RP 2255
- RP-2255
Pharmacology
- Indication
Not Available
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Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAcarbose The therapeutic efficacy of Acarbose can be increased when used in combination with Sulfathiourea. Acetohexamide The therapeutic efficacy of Acetohexamide can be increased when used in combination with Sulfathiourea. Albiglutide The therapeutic efficacy of Albiglutide can be increased when used in combination with Sulfathiourea. Alogliptin The therapeutic efficacy of Alogliptin can be increased when used in combination with Sulfathiourea. Benzylpenicillin Sulfathiourea may decrease the excretion rate of Benzylpenicillin which could result in a higher serum level. Bromocriptine The therapeutic efficacy of Bromocriptine can be increased when used in combination with Sulfathiourea. Canagliflozin The therapeutic efficacy of Canagliflozin can be increased when used in combination with Sulfathiourea. Chloroprocaine The therapeutic efficacy of Sulfathiourea can be decreased when used in combination with Chloroprocaine. Chlorpropamide The therapeutic efficacy of Chlorpropamide can be increased when used in combination with Sulfathiourea. Cholestyramine Cholestyramine can cause a decrease in the absorption of Sulfathiourea resulting in a reduced serum concentration and potentially a decrease in efficacy. 
Identify potential medication risksEasily compare up to 40 drugs with our drug interaction checker.Get severity rating, description, and management advice.Learn more - Food Interactions
- Not Available
Products
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- Badional / Fontamide
Categories
- ATC Codes
- J01EB08 — Sulfathiourea
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as aminobenzenesulfonamides. These are organic compounds containing a benzenesulfonamide moiety with an amine group attached to the benzene ring.
- Kingdom
- Organic compounds
- Super Class
- Benzenoids
- Class
- Benzene and substituted derivatives
- Sub Class
- Benzenesulfonamides
- Direct Parent
- Aminobenzenesulfonamides
- Alternative Parents
- Benzenesulfonyl compounds / Aniline and substituted anilines / Organosulfonic acids and derivatives / Aminosulfonyl compounds / Primary amines / Organopnictogen compounds / Organic oxides / Hydrocarbon derivatives
- Substituents
- Amine / Aminobenzenesulfonamide / Aminosulfonyl compound / Aniline or substituted anilines / Aromatic homomonocyclic compound / Benzenesulfonyl group / Hydrocarbon derivative / Organic nitrogen compound / Organic oxide / Organic oxygen compound
- Molecular Framework
- Aromatic homomonocyclic compounds
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- MXF9G4I1V5
- CAS number
- 515-49-1
- InChI Key
- UEMLYRZWLVXWRU-UHFFFAOYSA-N
- InChI
- InChI=1S/C7H9N3O2S2/c8-5-1-3-6(4-2-5)14(11,12)10-7(9)13/h1-4H,8H2,(H3,9,10,13)
- IUPAC Name
- (4-aminobenzenesulfonyl)thiourea
- SMILES
- NC(=S)NS(=O)(=O)C1=CC=C(N)C=C1
References
- General References
- Not Available
- External Links
- KEGG Drug
- D07239
- ChemSpider
- 2272143
- ChEBI
- 131723
- ChEMBL
- CHEMBL2107489
- ZINC
- ZINC000003873929
- Wikipedia
- Sulfathiourea
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.344 mg/mL ALOGPS logP 0.2 ALOGPS logP 0.3 Chemaxon logS -2.8 ALOGPS pKa (Strongest Acidic) 6.13 Chemaxon pKa (Strongest Basic) 2.25 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 98.21 Å2 Chemaxon Rotatable Bond Count 1 Chemaxon Refractivity 59.15 m3·mol-1 Chemaxon Polarizability 21.75 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS Not Available
Drug created at June 23, 2017 20:46 / Updated at February 21, 2021 18:54