Displaying drugs 9601 - 9625 of 10248 in total
BNT162b1 SARS-CoV-2 Vaccine
BNT162b1 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162b1 is a nucleoside modified mRNA (modRNA) vaccine encoding the receptor-binding domain (RBD) of the SARS-CoV-2 spike (S) protein together with a "foldon" trimerization domain derived from T4 fibritin...
Investigational
Matched Name: … BNT162b1 SARS-CoV-2 Vaccine …
Matched Description: … nucleoside modified mRNA (modRNA) vaccine encoding the receptor-binding domain (RBD) of the SARS-CoV-2 ... [L15007, L15012] Early results from a phase 1/2 study in 45 healthy adult volunteers demonstrated RBD-binding …
Matched Description: … nucleoside modified mRNA (modRNA) vaccine encoding the receptor-binding domain (RBD) of the SARS-CoV-2 ... [L15007, L15012] Early results from a phase 1/2 study in 45 healthy adult volunteers demonstrated RBD-binding …
Ethoxzolamide
Ethoxzolamide is a sulfonamide used as diuretic and in glaucoma. It inhibits carbonic anhydrase activity in proximal renal tubules to decrease reabsorption of water, sodium, potassium, bicarbonate. Its pharmacological activity thus confers the risk for hypokalemia.
Withdrawn
Matched Synonyms: … 6-Ethoxy-1,3-benzothiazole-2-sulfonamide …
Matched Iupac: … 6-ethoxy-1,3-benzothiazole-2-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 6-ethoxy-1,3-benzothiazole-2-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Efzofitimod
Efzofitimod (ATYR1923) is a fusion protein comprised of the immuno-modulatory domain of histidyl tRNA synthetase fused to the FC region of a human antibody. It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response in inflammatory disease states.
Investigational
Matched Synonyms: … Human IgG1Fc- iMod domain (amino acids 2-60) of human HARS fusion protein …
Matched Description: … It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response …
Matched Description: … It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response …
ATYR-1940
Investigational
Matched Synonyms: … Human recombinant histidyl-t-RNA synthetase (residues 2-506) …
9-Methyl Uric Acid
Experimental
9-(2-Deoxy-Beta-D-Ribofuranosyl)-6-Methylpurine
Experimental
Matched Name: … 9-(2-Deoxy-Beta-D-Ribofuranosyl)-6-Methylpurine …
Matched Iupac: … (2R,3S,5R)-2-(hydroxymethyl)-5-(6-methyl-9H-purin-9-yl)oxolan-3-ol …
Matched Iupac: … (2R,3S,5R)-2-(hydroxymethyl)-5-(6-methyl-9H-purin-9-yl)oxolan-3-ol …
Minodronic acid
Investigational
Matched Iupac: … (1-hydroxy-2-{imidazo[1,2-a]pyridin-3-yl}-1-phosphonoethyl)phosphonic acid …
Uprosertib
Uprosertib has been used in trials studying the treatment of Cancer, Melanoma, Solid Tumours, Cervical Cancer, and HER2/Neu Negative, among others.
Investigational
Matched Iupac: … N-[(2S)-1-amino-3-(3,4-difluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)furan ... -2-carboxamide …
Matched Salts cas: … 1047635-80-2 …
Matched Salts cas: … 1047635-80-2 …
Ibodutant
Ibodutant has been used in trials studying the treatment of Irritable Bowel Syndrome and Irritable Bowel Syndrome With Diarrhea.
Investigational
Matched Iupac: … 6-methyl-N-(1-{[(1R)-1-[({1-[(oxan-4-yl)methyl]piperidin-4-yl}methyl)carbamoyl]-2-phenylethyl]carbamoyl ... }cyclopentyl)-1-benzothiophene-2-carboxamide …
Matched Categories: … Receptors, Neurokinin-2, antagonists & inhibitors …
Matched Categories: … Receptors, Neurokinin-2, antagonists & inhibitors …
Sulprostone
Sulprostone has been used in trials studying Abortion, Induced.
Investigational
Matched Iupac: … (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxybut-1-en-1-yl]-5-oxocyclopentyl]-N-methanesulfonylhept …
Dorzagliatin
Dorzagliatin is under investigation in clinical trial NCT03173391 (Long-term Efficacy and Safety of HMS5552 in T2DM).
Investigational
Matched Iupac: … (2S)-2-[4-(2-chlorophenoxy)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl]-N-{1-[(2R)-2,3-dihydroxypropyl]-1H-pyrazol ... -3-yl}-4-methylpentanamide …
Curcuma xanthorrhiza oil
Curcuma xanthorrhiza oil is extracted from Curcuma xanthorrhiza Roxb., a member of the ginger family (Zingiberaceae) that is widely distributed in the region of Southeastern Asia . Curcuma xanthorrhiza is also known as Javanese Turmeric or Temoe Lawak . For centuries, Curcuma xanthorrhiza oil has been used as a traditional...
Nutraceutical
Matched Description: … _Curcuma xanthorrhiza_ oil is comprised of 1-2% of curcumin and 3-12% volatile oil, which mainly contains …
Gantenerumab
Alzheimer's disease (AD) is the most common cause of dementia in elderly patients, with classical histopathological hallmarks including extracellular amyloid-beta (Aβ) plaques and intraneuronal neurofibrillary tangles (NFTs). As the classical view of AD pathology posits that Aβ accumulation triggers tau hyperphosphorylation and aggregation to form NFTs and cause neurodegeneration, large...
Investigational
Belzupacap Sarotalocan
Investigational
1h-Benoximidazole-2-Carboxylic Acid
Experimental
Matched Name: … 1h-Benoximidazole-2-Carboxylic Acid …
Matched Iupac: … 1H-1,3-benzodiazole-2-carboxylic acid …
Matched Iupac: … 1H-1,3-benzodiazole-2-carboxylic acid …
Guanosine-2',3'-cyclophosphorothioate
Experimental
Matched Name: … Guanosine-2',3'-cyclophosphorothioate …
Matched Iupac: … 1,3,2]dioxaphosphol-4-yl]-2-amino-6,9-dihydro-3H-purin-6-one ... 9-[(2S,3aR,4R,6R,6aR)-2-hydroxy-6-(hydroxymethyl)-2-sulfanylidene-tetrahydro-2H-2lambda5-furo[3,4-d][ …
Matched Iupac: … 1,3,2]dioxaphosphol-4-yl]-2-amino-6,9-dihydro-3H-purin-6-one ... 9-[(2S,3aR,4R,6R,6aR)-2-hydroxy-6-(hydroxymethyl)-2-sulfanylidene-tetrahydro-2H-2lambda5-furo[3,4-d][ …
Evorpacept
evorpacept is under investigation in clinical trial NCT04755244 (A Study of Evorpacept (ALX148) With Venetoclax and Azacitidine for Acute Myeloid Leukemia (ASPEN-05)).
Investigational
Pantothenyl-Aminoethanol-Acetate Pivalic Acid
Experimental
Matched Iupac: … (3R)-3-[(2-{[2-(acetyloxy)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropyl 2,2-dimethylpropanoate …
MK-7145
MK-7145 has been used in trials studying the treatment of Hypertension and Renal Insufficiency.
Investigational
Matched Iupac: … 5-[(1R)-1-hydroxy-2-{4-[(2R)-2-hydroxy-2-(4-methyl-1-oxo-1,3-dihydro-2-benzofuran-5-yl)ethyl]piperazin ... -1-yl}ethyl]-4-methyl-1,3-dihydro-2-benzofuran-1-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
PSI-352938
PSI-352938 has been used in trials studying the treatment of Hepatitis C and Hepatitis C, Chronic.
Investigational
Matched Iupac: … (2S,4aR,6R,7R,7aR)-6-(2-amino-6-ethoxy-9H-purin-9-yl)-7-fluoro-7-methyl-2-(propan-2-yloxy)-hexahydro- ... 2lambda5-furo[3,2-d][1,3,2]dioxaphosphinin-2-one …
[(1S)-4-(1-Aminobutylideneamino)-1-carboxybutyl]azanium
Experimental
Matched Name: … [(1S)-4-(1-Aminobutylideneamino)-1-carboxybutyl]azanium …
Matched Iupac: … (1S)-4-[(E)-(1-aminobutylidene)amino]-1-carboxybutan-1-aminium …
Matched Iupac: … (1S)-4-[(E)-(1-aminobutylidene)amino]-1-carboxybutan-1-aminium …
4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME
Experimental
Matched Name: … 4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME …
Matched Iupac: … (E)-[(4-hydroxyphenyl)methylidene]amino cyclohexanecarboxylate …
Matched Iupac: … (E)-[(4-hydroxyphenyl)methylidene]amino cyclohexanecarboxylate …
8-Benzo[1,3]Dioxol-,5-Ylmethyl-9-Butyl-2-Fluoro-9h-Purin-6-Ylamine
Experimental
Matched Name: … 8-Benzo[1,3]Dioxol-,5-Ylmethyl-9-Butyl-2-Fluoro-9h-Purin-6-Ylamine …
Matched Iupac: … 8-[(2H-1,3-benzodioxol-5-yl)methyl]-9-butyl-2-fluoro-9H-purin-6-amine …
Matched Iupac: … 8-[(2H-1,3-benzodioxol-5-yl)methyl]-9-butyl-2-fluoro-9H-purin-6-amine …
Displaying drugs 9601 - 9625 of 10248 in total