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Displaying drugs 9651 - 9675 of 10915 in total

3-(Mercaptomethylene)Pyridine

Experimental
Matched Name: … 3-(Mercaptomethylene)Pyridine …
Matched Iupac: … (pyridin-3-yl)methanethiol …

Tanespimycin

Tanespimycin, manufactured by Conforma Therapeutics is under development as a small molecule inhibitor of heat shock protein 90 (HSP90). It is developed for the treatment of several types of cancer, solid tumors or chronic myelogenous leukemia.
Investigational
Matched Iupac: … en-1-yl)amino]-2-azabicyclo[16.3.1]docosa-1(21),2,4,6,10,18-hexaen-9-yl]oxy}methanimidic acid ... ,9S,10E,12S,13R,14S,16R)-3,13-dihydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-20,22-dioxo-19-[(prop-2- …

cis-Vaccenic acid

Experimental

beta-Alanine

beta-Alanine is an amino acid formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. A rare genetic disorder, hyper-beta-alaninemia, has been reported.
Experimental
Matched Synonyms: … 3-aminopropanoic acid ... 3-aminopropionic acid …
Matched Iupac: … 3-aminopropanoic acid …

(4R)-limonene

Limonene is common in cosmetic products. As the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a flavoring to mask the bitter taste of alkaloids, and as a fragrant in perfumery.
Investigational
Matched Synonyms: … (4R)-1-methyl-4-isopropenylcyclohex-1-ene ... (R)-4-isopropenyl-1-methyl-1-cyclohexene ... (R)-1-methyl-4-(1-methylethenyl)cyclohexene …
Matched Iupac: … (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene …

Nz-(1-Carboxyethyl)-Lysine

Experimental
Matched Name: … Nz-(1-Carboxyethyl)-Lysine …
Matched Iupac: … (2S)-2-amino-6-{[(1R)-1-carboxyethyl]amino}hexanoic acid …

12-Bromododecanoic Acid

Experimental

4-Hydroxybutan-1-Aminium

Experimental
Matched Name: … 4-Hydroxybutan-1-Aminium …
Matched Iupac: … 4-hydroxybutan-1-aminium …

Human interferon omega-1

Human interferon omega 1 (IFN-omega 1 = IFN-alpha II1) is a recently discovered protein structurally related to IFN-alpha and -beta. It occurs naturally in the human body and is currently being manufactured by Intarcia through genetic engineering. There are multiple routes for administration of omega interferon: injection, an implantable subcutaneous...
Investigational
Matched Synonyms: … Interferon omega-1 ... Human interferon omega 1 …
Matched Name: … Human interferon omega-1 …
Matched Description: … Human interferon omega 1 (IFN-omega 1 = IFN-alpha II1) is a recently discovered protein structurally ... The biological activities of IFN-omega 1 and its physiological role are not known to date. …

Florilglutamic acid F-18

Florilglutamic acid F-18 is under investigation in clinical trial NCT02370563 (PET Imaging of Intracranial Cancers With 18F-FSPG).
Investigational
Matched Iupac: … (2S,4S)-2-amino-4-[3-(¹⁸F)fluoropropyl]pentanedioic acid …

18-methoxycoronaridine

18-methoxycoronaridine is under investigation in clinical trial NCT03084952 (Phase 2 Trial to Evaluate 18-Methoxycoronaridine Efficacy, Safety and Tolerability in Cutaneous Leishmaniasis Patients).
Investigational
Matched Iupac: … -2(10),4(9),5,7-tetraene-1-carboxylate ... methyl (1S,15R,17R,18S)-17-(2-methoxyethyl)-3,13-diazapentacyclo[13.3.1.0^{2,10}.0^{4,9}.0^{13,18}]nonadeca …
Matched Description: … 18-methoxycoronaridine is under investigation in clinical trial NCT03084952 (Phase 2 Trial to Evaluate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Apamistamab iodine I-131

Investigational

Neflamapimod

Neflamapimod has been used in trials studying the treatment of Alzheimer's Disease and Mild Cognitive Impairment.
Investigational
Matched Iupac: … 5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)sulfanyl]-6H-pyrimido[1,6-b]pyridazin-6-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

19-Nor-4-androstenedione

Experimental
Illicit

Peginterferon alfacon-1

PEGylation is a technology for the chemical attachment of polyethylene glycol (PEG) polymer chains to a broad range of drug substances such as peptides and proteins including antibody fragments; small molecules, and other drugs. [Infergen] is a bio-engineered type I interferon alpha that is FDA-approved for the treatment of patients...
Investigational
Matched Synonyms: … PEG INF alfacon-1 ... PEG-interferon alfacon-1 ... Pegylated interferon alfacon-1 …
Matched Name: … Peginterferon alfacon-1 …

10-hydroxycamptothecin

10-hydroxycamptothecin is under investigation in clinical trial NCT00956787 (Study of AR-67 (DB-67) in Myelodysplastic Syndrome (MDS)).
Investigational
Matched Iupac: … 21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione ... 19S)-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1( …

Talditercept alfa

Talditercept alfa is under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy).
Investigational

Idroxioleic acid

Investigational
Matched Synonyms: … 2-hydroxyoleic acid ... (z)-2-hydroxyoctadec-9-enoic acid ... Cis-2-hydroxy-9-octadecenoic acid …
Matched Iupac: … (9Z)-2-hydroxyoctadec-9-enoic acid …

Fibrin

Experimental

Kabiramide C

Experimental
Matched Iupac: … {6,9}]hentriaconta-1(28),2(31),4,6(30),8,24,26(29)-heptaen-18-one ... yl]-10,22-dimethoxy-11,14,21-trimethyl-3,7,19,27-tetraoxa-29,30,31-triazatetracyclo[24.2.1.1^{2,5}.1^ ... 2S,3S,7R,8R,9R,10E)-11-[(hydroxymethyl)(methyl)amino]-2,8-dimethoxy-3,7,9-trimethyl-6-oxoundec-10-en-1- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Temafloxacin

Temafloxacin is an antibiotic agent belonging to the fluoroquinolone drug class. It was first approved for use in the U.S. market in 1992, but was withdrawn shortly due to the reports of serious adverse reactions, such as allergic reactions and hemolyric anemia, resulting in three deaths.
Withdrawn
Matched Iupac: … 1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Fleroxacin

Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase. Fleroxacin is not an inhibitor of CYP1A2.
Experimental
Matched Iupac: … 6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Difloxacin

Difloxacin is a synthetic fluoroquinolone used in veterinary. As an antibacterial, it presents a broad bactericidal spectrum and its effects are dependent on its concentration. However, it presents a reduced efficacy when compared to other fluoroquinolone antibacterials.
Vet approved
Matched Iupac: … 6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Salts cas: … 91296-86-5 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

AZD-8055

AZD8055 has been used in trials studying the treatment of Cancer, Lymphomas, Solid Tumors, MALIGNANT GLIOMA, and brainstem glioma, among others.
Investigational
Matched Iupac: … (5-{2,4-bis[(3S)-3-methylmorpholin-4-yl]pyrido[2,3-d]pyrimidin-7-yl}-2-methoxyphenyl)methanol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Branebrutinib

Branebrutinib is under investigation in clinical trial NCT02705989 (Safety, Tolerability and Relative Bioavailability Study of BMS-986195 in Healthy Subjects).
Investigational
Matched Iupac: … 4-[(3S)-3-(but-2-ynamido)piperidin-1-yl]-5-fluoro-2,3-dimethyl-1H-indole-7-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Displaying drugs 9651 - 9675 of 10915 in total