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Displaying drugs 951 - 975 of 1533 in total

Cefaloridine

Cephaloridine or cefaloridine is a first generation semisynthetic cephalosporin. It is derived from cephalosporin C and is a zwitterion at physiological pH.
Experimental
Withdrawn
Matched Synonyms: … (6R,7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)- 7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1- azabicyclo[4.2.0 …
Matched Iupac: … 1-{[(6R,7R)-2-carboxylato-7-{[1-hydroxy-2-(thiophen-2-yl)ethylidene]amino}-8-oxo-5-thia-1-azabicyclo[ …

Morin

Experimental

3-Bromo-7-Nitroindazole

Experimental
Matched Name: … 3-Bromo-7-Nitroindazole …
Matched Iupac: … 3-bromo-7-nitro-1H-indazole …

Chrysin

Experimental

Oxypurinol

Oxypurinol, an inhibitor of xanthine oxidase, is a metabolite of allopurinol.
Investigational

SXR-1096

Investigational
Matched Synonyms: … 4h-3,1-benzoxazin-4-one, 6-ethoxy-7-methoxy-2-(2-(methylthio)phenyl)- ... 6-ethoxy-7-methoxy-2-(2-methylsulfanylphenyl)-3,1-bensoxazin-4-one …
Matched Iupac: … 6-ethoxy-7-methoxy-2-[2-(methylsulfanyl)phenyl]-4H-3,1-benzoxazin-4-one …

PA3-17

PA3-17 is CD7-directed chimeric antigen receptor (CAR) T-cell therapy.
Investigational

(3R,4S,5S,7R,9E,11R,12R)-12-ETHYL-4-HYDROXY-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE

Experimental

7-Hydroxystaurosporine

Experimental
Investigational
Matched Name: … 7-Hydroxystaurosporine …

(3S,5R,7R,8S,9S,10R)-7-(hydroxymethyl)-3-(2-naphthyl)-1,6-dioxa-2-azaspiro[4.5]decane-8,9,10-triol

Experimental
Matched Name: … (3S,5R,7R,8S,9S,10R)-7-(hydroxymethyl)-3-(2-naphthyl)-1,6-dioxa-2-azaspiro[4.5]decane-8,9,10-triol …
Matched Iupac: … (3S,5R,7R,8S,9S,10R)-7-(hydroxymethyl)-3-(naphthalen-2-yl)-1,6-dioxa-2-azaspiro[4.5]decane-8,9,10-triol …

Tubercidin

An antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic acids.
Experimental
Matched Synonyms: … 7-deazaadenosine …
Matched Iupac: … (2R,3R,4S,5R)-2-{4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-5-(hydroxymethyl)oxolane-3,4-diol …

Nisevokitug

Nisevokitug is a monoclonal antibody targeted against transforming growth factor beta (TGFβ) under investigation in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and Efficacy of Novel Ruxolitinib Combinations in Myelofibrosis Patients).
Investigational

Borneol

Experimental

3-(4-(1,5-Naphthyridine)imidazole(1,2-a) pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine)))

Investigational
Matched Synonyms: … 1,5-naphthyridine, 4-(7-(4-(4-methyl-1-piperazinyl)phenyl)imidazo(1,2-a)pyridin-3-yl)- ... 3-(4-(1,5-napthrydine)imidazole(1,2-a)pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine))) …
Matched Name: … 3-(4-(1,5-Naphthyridine)imidazole(1,2-a) pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine))) …
Matched Iupac: … 4-{7-[4-(4-methylpiperazin-1-yl)phenyl]imidazo[1,2-a]pyridin-3-yl}-1,5-naphthyridine …

Lomvastomig

Lomvastomig is under investigation in clinical trial NCT04785820 (A Study of Lomvastomig (RO7121661) and Tobemstomig (RO7247669) Compared With Nivolumab in Participants With Advanced or Metastatic Squamous Cell Carcinoma of the Esophagus).
Investigational

TPI-287

Investigational

7,8-Diamino-Nonanoic Acid

Experimental

DSP-5336

DSP-5336 is a menin inhibitor.
Investigational
Matched Synonyms: … BENZAMIDE, 5-FLUORO-2-((4-(7-(((1S,3S,4R)-5-METHYLENE-2-AZABICYCLO(2.2.2)OCT-3-YL)CARBONYL)-2,7-DIAZASPIRO …
Matched Iupac: … 5-fluoro-2-[(4-{7-[(1S,3S,4R)-5-methylidene-2-azabicyclo[2.2.2]octane-3-carbonyl]-2,7-diazaspiro[3.5] …

7-Methyl-7,8-dihydroguanosine 5'-(tetrahydrogen triphosphate)

Experimental
Matched Name: … 7-Methyl-7,8-dihydroguanosine 5'-(tetrahydrogen triphosphate) …
Matched Iupac: … ({[({[(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-6,7,8,9-tetrahydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2 …

Colforsin

Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland.
Experimental
Investigational

KH064

Experimental
Matched Synonyms: … 5-(4-Benzyloxyphenyl)-4S-(7-phenylheptanoylamino)pentanoic acid ... (S)-5-(4-Benzyloxy-phenyl)-4-(7-phenyl-heptanoylamino)-pentanoic acid …
Matched Iupac: … (4S)-5-[4-(benzyloxy)phenyl]-4-(7-phenylheptanamido)pentanoic acid …

Dazostinag

Dazostinag is under investigation in clinical trial NCT04420884 (A Study of Dazostinag as Single Agent and Dazostinag in Combination With Pembrolizumab in Adults With Advanced or Metastatic Solid Tumors).
Investigational
Matched Synonyms: … -7-fluoro-, cyclic (2′→5′)-nucleotide ... 7-Deazainosine, [P(R)]-2′-deoxy-2′-fluoro-5′-O-[(R)-hydroxymercaptophosphinyl]-P-thioadenylyl-(3′→5′) …

Dabocemagene autoficel

Dabocemagene autoficel is an ex vivo, autologous cell-based gene therapy. It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen. Developed by Castle Creek Biosciences Inc., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa.
Investigational

(5S,7R,8S,9S,10R)-3-Amino-8,9,10-trihydroxy-7-(hydroxymethyl)-6-oxa-1,3-diazaspiro[4.5]decane-2,4-dione

Experimental
Matched Name: … (5S,7R,8S,9S,10R)-3-Amino-8,9,10-trihydroxy-7-(hydroxymethyl)-6-oxa-1,3-diazaspiro[4.5]decane-2,4-dione …
Matched Iupac: … (5S,7R,8S,9S,10R)-3-amino-8,9,10-trihydroxy-7-(hydroxymethyl)-6-oxa-1,3-diazaspiro[4.5]decane-2,4-dione …

(3S,5R,7R,8S,9S,10R)-7-(hydroxymethyl)-3-(4-methylphenyl)-1,6-dioxa-2-azaspiro[4.5]decane-8,9,10-triol

Experimental
Matched Name: … (3S,5R,7R,8S,9S,10R)-7-(hydroxymethyl)-3-(4-methylphenyl)-1,6-dioxa-2-azaspiro[4.5]decane-8,9,10-triol …
Matched Iupac: … (3S,5R,7R,8S,9S,10R)-7-(hydroxymethyl)-3-(4-methylphenyl)-1,6-dioxa-2-azaspiro[4.5]decane-8,9,10-triol …
Displaying drugs 951 - 975 of 1533 in total