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Displaying drugs 951 - 975 of 3518 in total
Investigational
Matched Synonyms: … L-ISOLEUCINE, N2-(2-METHYL-1-OXOPROPYL)-L-GLUTAMINYL-L-THREONYL-L-LEUCYL-(.ALPHA.S,3S,6R)-3-AMINO-6-HYDROXY ... (S)-2-ISOBUTYRYLAMINO-PENTANEDIOIC ACID 5-AMIDE 1-{[(2S,5S,8S,11R,12S,15S,18S,21R)-2,8-BIS-((S)-SEC-BUTYL ... -.ALPHA.-((1S)-1-METHYLPROPYL)-2-OXO-1-PIPERIDINEACETYL-N-METHYL-L-TYROSYL-, (6->2)-LACTONE …
Matched Name: … LM-030 …
Phytic acid is under investigation in clinical trial NCT01000233 (Value of Oral Phytate (InsP6) in the Prevention of Progression of the Cardiovascular Calcifications).
Investigational
Matched Synonyms: … Acido fitico ... Fytic acid ... Acide fytique …
Matched Name: … Phytic acid
Matched Iupac: … {[(1s,2R,3R,4r,5S,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl]oxy}phosphonic acid
Matched Description: … Phytic acid is under investigation in clinical trial NCT01000233 (Value of Oral Phytate (InsP6) in the …
Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis.[A3811, A260880, L40968] Abiraterone was first approved by the FDA and EMA on April, July, and September 2011, respectively. It is used to treat metastatic...
Approved
Matched Description: … hydrolysis by esterases, abiraterone acetate was developed as an orally bioavailable prodrug with enhanced ... Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17 ... ] and September 2011,[A260880] respectively. …
Matched Salts name: … Abiraterone acetate
Matched Categories: … Antineoplastic and Immunomodulating Agents ... niraparib and abiraterone ... abiraterone and prednisolone ... Hormone Antagonists and Related Agents ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Abiraterone Acetate ... Abiraterone acetate ... Abiratred Abiraterone Acetate Tablets 250mg …
Experimental
Matched Name: … Furoyl-Leucine
Matched Iupac: … (2S)-2-[(furan-2-yl)formamido]-4-methylpentanoic acid
Approved
Experimental
Investigational
Matched Name: … D-Methionine
Matched Iupac: … (2R)-2-amino-4-(methylsulfanyl)butanoic acid
Matched Mixtures name: … NUTRINEAL PD]4 Peritoneal Dialysis Solution with 1.1% Amino Acids
Experimental
Matched Name: … Imino-Tryptophan
Matched Iupac: … 2-imino-3-(1H-indol-3-yl)propanoic acid
Investigational
Matched Synonyms: … (1r)-1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid ... Pyrano(3,4-b)indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-, (1r)- ... Pyrano(3,4-b)indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-, (r)- …
Experimental
Matched Name: … N-alpha-Acetyl-3,5-diiodotyrosyl-D-threonine
Matched Iupac: … (2R,3R)-2-[(2S)-2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanamido]-3-hydroxybutanoic acid
Experimental
Matched Name: … S-2-(Boronoethyl)-L-Cysteine
Produced during the urea cycle, ornithine is an amino acid produced from the splitting off of urea from arginine. L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine.
Approved
Nutraceutical
Matched Synonyms: … L-Ornithine ... (S)-2,5-Diaminopentanoic acid ... (S)-2,5-diaminovaleric acid
Matched Iupac: … (2S)-2,5-diaminopentanoic acid
Matched Description: … L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine ... Produced during the urea cycle, ornithine is an amino acid produced from the splitting off of urea from ... arginine. …
Matched Mixtures name: … GNC PP L-Arginine L-Ornithine Tablet ... PRIMENE 10% AMINO ACID INTRAVENOUS INFUSION ... Primene 10%-liq IV …
Matched Salts name: … Ornithine hydrochloride
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Amino Acids ... Amino Acids, Basic …
Matched Products: … L-ORNITHINE L-ASPARTATE ... L-ORNITHIN-L-ASPARTATE ... L - ORNITHINE - L - ASPARTATE …
Investigational
Matched Synonyms: … Immunoglobulin g4 (224-proline,233-alanine,234-alanine), anti-(human dickkopf-1) (human-mus musculus …
Fosfomycin was discovered in 1969 by scientists at the Spanish Penicillin and Antibiotics Company and is produced by Streptomyces fradiae.[A229338,A230348] It may also be produced synthetically and is commercially available as the disodium salt for intravenous administration and as the calcium or trometamol salt for oral administration. In terms of...
Approved
Matched Synonyms: … L-cis-1,2-epoxypropylphosphonic acid ... (1R,2S)-epoxypropylphosphonic acid ... (-)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid
Matched Iupac: … [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid
Matched Description: … [A230348] Due to its ease of administration as a single 3-gram oral dose and desirable safety profile ... Fosfomycin was discovered in 1969 by scientists at the Spanish Penicillin and Antibiotics Company and ... group and an epoxide ring. …
Stanolone acetate is a synthetic androgen and anabolic steroid and a dihydrotestosterone ester that was never marketed.
Experimental
Matched Synonyms: … Androstanolone acetate ... Dihydrotestosterone acetate
Matched Name: … Stanolone acetate
Matched Iupac: … (1S,3aS,3bR,5aS,9aS,9bS,11aS)-9a,11a-dimethyl-7-oxo-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl acetate
Matched Description: … Stanolone acetate is a synthetic androgen and anabolic steroid and a dihydrotestosterone ester that was …
Matched Categories: … Testosterone and derivatives …
Experimental
Matched Name: … 2-Hydroxy-Tryptophan
Matched Iupac: … (2S)-2-amino-3-(2-hydroxy-1H-indol-3-yl)propanoic acid
Experimental
Matched Name: … Magnesium aspartate hydrochloride
Matched Iupac: … magnesium(2+) (2S)-2-aminobutanedioate hydrochloride
Matched Salts name: … Magnesium aspartate hydrochloride trihydrate …
Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear factor kappa-B ligand (RANKL), suppresses bone resorption via inhibiting RANK-mediated activation of osteoclasts. It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss. Chemically, it consists of 2 heavy...
Approved
Matched Description: … 215 amino acids and each heavy chain consisting of 448 amino acids with 4 intramolecular disulfides. ... It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss ... [A263071] Chemically, it consists of 2 heavy and 2 light chains, with each light chain consisting of …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … Prolia ... PROLIA ... PROLIA® …
Pegargiminase is an anticancer agent.
Investigational
Matched Synonyms: … Arginine deiminase pegylated ... Pegylated arginine deiminase …
Matched Categories: … Enzymes and Coenzymes …
Experimental
Matched Name: … N-PYRIDOXYL-D-GLUTAMIC ACID-5'-MONOPHOSPHATE …
Matched Iupac: … (2R)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanedioic acid
Zeluvalimab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (Mcrpc)).
Investigational
Matched Synonyms: … Immunoglobulin g1 (295-cysteine,300-glycine,305-cysteine), anti-(human programmed cell death 1) (human …
Matched Description: … Zeluvalimab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for …
The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus (HCV) activity. Upon administration, valopicitabine is converted into 2'-C-methylcytidine; upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus...
Experimental
Matched Synonyms: … 2'-C-methylcytidine 3'-O-L-valinyl ester …
Matched Description: … This blocks viral production of HCV RNA and thus viral replication. [from NCI] ... upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and ... The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Investigational
Matched Synonyms: … L-prolinamide, 4-chloro-n-(4-mercapto-1-oxobutyl)-l-phenylalanyl-3-(2-thienyl)-l-alanyl-l-valyl-l-asparaginyl-l-cysteinyl-n …
Cadisegliatin is under investigation in clinical trial NCT06334133 (Cadisegliatin as Adjunctive Therapy in Type 1 Diabetes).
Investigational
Matched Synonyms: … 2-((2-(3-cyclohexyl-3-((1r,4r)-4-propoxycyclohexyl)ureido)thiazol-5-yl)thio)acetic acid ... [(2-{[cyclohexyl(trans-4-propoxycyclohexyl)carbamoyl]amino}-1,3-thiazol-5-yl)sulfanyl]acetic acid ... Acetic acid, 2-[[2-[[[cyclohexyl(trans-4-propoxycyclohexyl)amino]carbonyl]amino]-5-thiazolyl]thio]- …
Investigational
Matched Synonyms: … Tolmetin glycine amide …
Matched Iupac: … 2-{2-[1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetamido}acetic acid
Fosclevudine alafenamide is under investigation in clinical trial NCT05238844 (A Study of Safety and Efficacy of ATI-2173 and Vebicorvir in Combination With Tenofovir Disoproxil Fumarate in Subjects With Chronic Hepatitis B Virus Infection).
Investigational
Matched Synonyms: … L-alanine, n-((s)-hydroxyphenoxyphosphinyl)-, 1-methylethyl ester, 5'-ester with 1-(2-deoxy-2-fluoro- ... -l-arabinofuranosyl)-5-methyl-2,4(1h,3h)-pyrimidinedione …
Matched Description: … Fosclevudine alafenamide is under investigation in clinical trial NCT05238844 (A Study of Safety and ... Efficacy of ATI-2173 and Vebicorvir in Combination With Tenofovir Disoproxil Fumarate in Subjects With …
A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)
Approved
Illicit
Matched Salts name: … Diethylpropion hydrochloride
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Diethylpropion Hydrochloride ... Diethylpropion Hydrochloride ER ... Diethylpropion HydrochlorideER ER …
Displaying drugs 951 - 975 of 3518 in total