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Displaying drugs 951 - 975 of 1574 in total
PRTX-100 is a highly-purified form of Staphylococcal Protein A that binds directly to monocytes and a subset of B-cells that are involved in the development and progression of various autoimmune diseases. These binding interactions enable the compound to modulate the function of these cells and restore the balance of the...
Investigational
Matched Synonyms: … Staphylococcus aureus protein A
Matched Description: … subset of B-cells that are involved in the development and progression of various autoimmune diseases ... PRTX-100 is a highly-purified form of Staphylococcal Protein A that binds directly to monocytes and a ... These binding interactions enable the compound to modulate the function of these cells and restore the …
Tylosin is a bacteriostatic macrolide antibiotic and feed additive used in veterinary medicine. It has a broad spectrum of activity against Gram-positive organisms and a limited range of Gram-negative organisms. Tylosin is produced as a fermentation product of Streptomyces fradiae.
Vet approved
Matched Synonyms: … Tylosin A
Matched Description: … Tylosin is a bacteriostatic macrolide antibiotic and feed additive used in veterinary medicine. ... It has a broad spectrum of activity against Gram-positive organisms and a limited range of Gram-negative ... Tylosin is produced as a fermentation product of Streptomyces fradiae. …
Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Investigational
Matched Description: … osteoperosis and Paget's disease[FDA Label][A959,A203111]. ... Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of …
Matched Categories: … Calcium-Regulating Hormones and Agents ... risedronic acid and colecalciferol ... risedronic acid and calcium, sequential ... Drugs Affecting Bone Structure and Mineralization ... risedronic acid, calcium and colecalciferol, sequential …
Matched Products: … ACTONEL ONCE-A-WEEK ... ACTONEL ONCE A WEEK ... ACTONEL ONCE-A-MONTH …
Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … 1 and Type 2 Diabetes. ... into internal organs and tissues such as the liver, fat cells, and skeletal muscle. ... Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type
Matched Mixtures name: … Soliqua SoloStar 100units/mL+33mcg/mL solution for injection in a pre-filled pen ... SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 50MCG/ML ... SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 33MCG/ML …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin glargine and lixisenatide ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … BASALOG 100 IU/mL, SOLUTION FOR INJECTION IN A VIAL ... LANTUS 100 Units/ml Solution for injection in a vial ... LANTUS SOLOSTAR 100IU/ML SOLUTION FOR INJECTION IN A PRE-FILLED PEN …
Coagulation Factor XIII A-Subunit (Recombinant), also known as catridecacog, is a recombinant form of the Factor XIII-A2 homodimer composed of two factor XIII (FXIII) A-subunits [FDA Label]. For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key coagulation factor is essential...
Approved
Matched Synonyms: … Factor XIII A-Subunit (Recombinant) ... Coagulation Factor XIII A-Subunit (recombinant) ... Blood Coagulation Factor XIII (Synthetic Human A-Chain Precursor) …
Matched Description: … product Tretten, and in the EU as NovoThirteen. ... Within the body, FXIII circulates as a heterotetramer composed of 2 catalytic A-subunits and 2 non-catalytic ... As a result, the active transglutaminase from subunit A cross-links fibrin and other proteins resulting …
Matched Categories: … Blood and Blood Forming Organs …
Insulin glulisine is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … Type 1 and Type 2 Diabetes. ... into internal organs and tissues such as the liver, fat cells, and skeletal muscle. ... Insulin is an important treatment in the management of Type 1 Diabetes (T1D) which is caused by an autoimmune …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Insulins and Analogues for Injection, Fast-Acting ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Apidra SoloStar 100 Units/ml Solution for injection in a pre-filled pen ... APIDRA SOLOSTAR 100 UNITS/ML, SOLUTION FOR INJECTION IN A PRE-FILLED PEN …
A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
Approved
Matched Description: … , bladder, and kidneys. ... It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges ... It may cause a superinfection with gram-positive organisms. …
Matched Categories: … Drugs that are Mainly Renally Excreted …
Matched Products: … AZBIOS® 1G POLVO PARA RECONSTITUIR A SOLUCION INYECTABLE ... AZTREONAM 1G POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.
Approved
Matched Synonyms: … 10,11-dihydro-5-(γ-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene ... 10,11-dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-Δ5,γ-propylamine ... 5-(γ-dimethylaminopropylidene)-5H-dibenzo[a,d][1,4]cycloheptadiene …
Matched Description: … Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ... ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961 ... [A259342] Amitriptyline has been investigated in the treatment of pain-related conditions, attributed …
Matched Mixtures name: … Perphenazine and Amitriptyline Hydrochloride ... Perphenazine and Amitriptyline Hydrochloride ... Chlordiazepoxide and Amitriptyline Hydrochloride …
Matched Categories: … amitriptyline and psycholeptics ... Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Drugs that are Mainly Renally Excreted ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index …
Matched Products: … Apo-amitriptyline ... Ag-amitriptyline ... APO-AMITRIPTYLINE 25MG TABLET …
Experimental
Matched Synonyms: … Medimin A ... Methoxy PEG-12 all-trans-retinamide …
Investigational
Matched Synonyms: … VITAMIN A ACETATE C20-D3 …
Protriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, protriptyline does not affect mood or arousal, but may cause sedation. In depressed individuals, protriptyline exerts a positive...
Approved
Matched Synonyms: … 5-(3-methylaminopropyl)-5H-dibenzo[a,d]cycloheptene ... 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine ... N-methyl-5H-dibenzo[a,d]cycloheptene-5-propanamine …
Matched Description: … TCAs also block histamine H<sub>1sub> receptors, alpha<sub>1sub>-adrenergic receptors and muscarinic ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... In addition, TCAs down-regulate cerebral cortical β-adrenergic receptors and sensitize post-synaptic …
Nadofaragene firadenovec (nadofaragene firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFNα2b). It was approved by the FDA on December 2022 for the treatment of high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without...
Approved
Investigational
Matched Synonyms: … Replication-deficient adenovirus type 5 (ad5) vector encoding the human interferon alpha 2 (ifna2, interferon …
Matched Description: … [L44381,L44431] BCG-unresponsive NMIBC has a high recurrence and is notably difficult to treat. ... across the urothelium and promotes the transduction of IFNα2b. ... serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFNα2b). …
Matched Categories: … Cellular and Gene Therapy ... Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents …
Experimental
Matched Name: … Octanoyl-Coenzyme A
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides ... Thioesters of coenzyme A
Experimental
Matched Name: … Dephospho Coenzyme A
Experimental
Matched Name: … Sinapoyl coenzyme A
Experimental
Matched Name: … Succinyl-Coenzyme A
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides ... Thioesters of coenzyme A
Experimental
Matched Name: … Nitromethyldethia coenzyme A
BW-A 58C, also known as 2-(4-tert-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone, is an experimental naphthoquinone antimalarial drug which undergoes extensive alkyl hydroxylation to a single t-butylhydroxy metabolite in man in vivo and also in human liver microsomes, where this is catalysed primarily by a 54 kDa CYP2C9 form of cytochrome P450, P450hB20-27.
Experimental
Matched Name: … BW-A 58C …
Matched Description: … in man in vivo and also in human liver microsomes, where this is catalysed primarily by a 54 kDa CYP2C9 ... BW-A 58C, also known as 2-(4-tert-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone, is an experimental naphthoquinone ... antimalarial drug which undergoes extensive alkyl hydroxylation to a single t-butylhydroxy metabolite …
Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of ABT-981 in Patients With Knee Osteoarthritis).
Investigational
Matched Synonyms: … (synthetic human a-1234138 heavy chain), disulfide with synthetic human a-1234138 light chain, dimer …
Matched Description: … , and Pharmacodynamic Effects of ABT-981 in Patients With Knee Osteoarthritis). ... Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Name: … Methacrylyl-Coenzyme A
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Name: … Feruloyl Coenzyme A
Coenzyme A persulfide is a possible in vivo inhibitor of mammalian short chain acyl-CoA dehydrogenase.
Experimental
Matched Name: … Coenzyme A persulfide …
Matched Description: … Coenzyme A persulfide is a possible in vivo inhibitor of mammalian short chain acyl-CoA dehydrogenase …
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides …
Salvianolic acid A is under investigation in clinical trial NCT03908242 (Phase I Study of Continuous Administration of Salvianolic Acid A Tablet).
Investigational
Matched Name: … Salvianolic acid A
Matched Description: … Administration of Salvianolic Acid A Tablet). ... Salvianolic acid A is under investigation in clinical trial NCT03908242 (Phase I Study of Continuous …
Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that promotes T-cell development, contributing to the immune response. Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better bioavailability. This drug is currently being investigated in the areas...
Investigational
Matched Synonyms: … Recombinant human interleukin-7 fused to a hybrid crystallizable fragment region of a human antibody ... Recombinant human interleukin-7 fused to a hybrid crystallizable fragment region of a human antibody …
Matched Description: … Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better ... This drug is currently being investigated in the areas of oncology, immunology, and infectious disease ... Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Approved
Experimental
Matched Mixtures name: … AXE BRAND HEAT OIL …
Matched Products: … Nwk A-FV …
Displaying drugs 951 - 975 of 1574 in total