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Displaying drugs 976 - 1000 of 1077 in total

6-BROMO-13-THIA-2,4,8,12,19-PENTAAZATRICYCLO[12.3.1.1~3,7~]NONADECA-1(18),3(19),4,6,14,16-HEXAENE 13,13-DIOXIDE

Experimental
Matched Name: … BROMO-13-THIA-2,4,8,12,19-PENTAAZATRICYCLO[12.3.1.1~3,7~]NONADECA-1(18),3(19),4,6,14,16-HEXAENE 13,13-DIOXIDE …

(3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium

Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias. [PubChem]
Experimental
Matched Name: … (3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium …
Matched Iupac: … [(2R)-3-carboxy-2-hydroxypropyl]trimethylazanium …
Matched Description: … Constituent of striated muscle and liver. ... It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias …

4-Carboxy-5-(1-Pentyl)Hexylsulfanyl-1,2,3-Triazole

Experimental
Matched Name: … 4-Carboxy-5-(1-Pentyl)Hexylsulfanyl-1,2,3-Triazole …

3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPIONIC

Experimental
Matched Name: … 3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPIONIC …

Citalopram

Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs.[A261316,A14720] Citalopram enhances serotonergic transmission through the...
Approved
Matched Description: … It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing ... and virtually no affinity for muscarinic, histaminergic, or GABAergic receptors. ... A14720] Citalopram enhances serotonergic transmission through the inhibition of serotonin reuptake, and …
Matched Products: … Septa-citalopram …

Telmisartan

Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to...
Approved
Investigational
Matched Mixtures name: … Telmisartan and Hydrochlorothiazide ... Telmisartan and Hydrochlorothiazide ... Telmisartan and Hydrochlorothiazide …
Matched Salts name: … Telmisartan sodium …
Matched Categories: … telmisartan and amlodipine ... telmisartan and diuretics ... rosuvastatin and telmisartan ... Angiotensin II receptor blockers (ARBs) and diuretics ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers …
Matched Products: … Septa-telmisartan …

Citric acid

A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … 3-carboxy-3-hydroxypentane-1,5-dioic acid …
Matched Mixtures name: … Heparin Sodium In 0.9% Sodium Chloride Injection ... Potassium Citrate, Sodium Citrate, and Citric Acid ... Care One Original Antacid and Pain Relief …
Matched Categories: … Alimentary Tract and Metabolism …

Haloperidol

Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide. While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain, it exerts its antipsychotic effect through its strong antagonism of the dopamine receptor (mainly D2), particularly within...
Approved
Matched Description: … Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently ... through its strong antagonism of the dopamine receptor (mainly D2), particularly within the mesolimbic and ... [F4645] It is also used off-label for the management of chorea associated with Huntington's disease and …
Matched Products: … ALOPERIDOLO CARLO ERBA …

5-(1-Carboxy-1-Phosphonooxy-Ethoxyl)-Shikimate-3-Phosphate

Experimental
Matched Name: … 5-(1-Carboxy-1-Phosphonooxy-Ethoxyl)-Shikimate-3-Phosphate …
Matched Iupac: … (3R,4S,5R)-5-[(1S)-1-carboxy-1-(phosphonooxy)ethoxy]-4-hydroxy-3-(phosphonooxy)cyclohex-1-ene-1-carboxylic …

Allopurinol

Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints . This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals . Allopurinol is a xanthine oxidase enzyme inhibitor that...
Approved
Matched Description: … This disease has been well-documented in historical medical records and appears in the biographies of ... enzyme inhibitor that is considered to be one of the most effective drugs used to decrease urate levels and ... It was initially approved by the FDA in 1966 [L5674] and is now formulated by several manufacturers [ …
Matched Salts name: … Allopurinol sodium …
Matched Products: … Allopurinol sodium …

Anti-CD7 CAR T-cell therapy

Investigational
Matched Synonyms: … A chimeric antigen receptor (CAR) immunotherapy directed against the target protein CD7 …
Matched Name: … Anti-CD7 CAR T-cell therapy …

CTX130

CTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen.
Investigational
Matched Synonyms: … Allogeneic CRISPR/Cas9-mediated genetically modified CAR T cells targeting CD70 antigen …
Matched Description: … CTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen …

(3S)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide

Experimental
Matched Name: … cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide …

{4-[(CARBOXYMETHOXY)CARBONYL]-3,3-DIOXIDO-1-OXONAPHTHO[1,2-D]ISOTHIAZOL-2(1H)-YL}ACETIC ACID

Experimental
Matched Name: … {4-[(CARBOXYMETHOXY)CARBONYL]-3,3-DIOXIDO-1-OXONAPHTHO[1,2-D]ISOTHIAZOL-2(1H)-YL}ACETIC ACID …

Rubella virus vaccine

Rubella virus vaccine is a live attenuated virus vaccine for active immunization against rubella (German measles) that is subcutaneously administered. It is prepared from RA 27/3 strain of live attenuated rubella virus. Rubella is a common childhood disease, caused by rubella virus (togavirus).
Approved
Investigational
Matched Synonyms: … Rubivirus rubella virus Wistar RA 27/3 whole …
Matched Mixtures name: … MEASLES AND RUBELLA VIRUS VACCINE LIVE ... SII Measles and Rubella Virus Vaccine live.Attenuated(Freeze-Dried) 10 doses ... SII Measles and Rubella Virus Vaccine live.Attenuated(Freeze-Dried) 1 dose …
Matched Categories: … measles, combinations with mumps and rubella, live attenuated ... measles, combinations with mumps, rubella and varicella, live attenuated …

N-(1-carboxy-3-phenylpropyl)phenylalanyl-alpha-asparagine

Experimental
Matched Name: … N-(1-carboxy-3-phenylpropyl)phenylalanyl-alpha-asparagine …
Matched Categories: … Amino Acids, Peptides, and Proteins …

B7-H3-specific chimeric antigen receptor T cells

Investigational
Matched Synonyms: … Autologous chimeric antigen receptor (CAR) T cells targeting B7-H3 ... chimeric antigen receptor (CAR) modified recombinant T cells targeting B7-H3 ... allogeneic T cells genetically modified to express anti-B7-H3 chimeric antigen receptor (CAR) …

PBCAR269A

Investigational
Matched Synonyms: … Allogeneic gene edited BCMA-directed CAR T cells …

Chamomile

Chamomile is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Investigational
Matched Synonyms: … Chamomilla Vulgaris Flower …
Matched Mixtures name: … Skin Care …

OriCar-017

Investigational
Matched Synonyms: … GPRC5D-CAR-T ... chimeric antigen receptor (CAR)-T cell therapy targeting G protein-coupled receptor class-C group-5 member-D …

Dorzolamide

Dorzolamide is a non-bacteriostatic sulfonamide derivative and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular hypertension. It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. Unlike oral CA inhibitors, dorzolamide...
Approved
Matched Synonyms: … (4S,trans)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide …
Matched Description: … Dorzolamide is a non-bacteriostatic sulfonamide derivative [A1304] and topical carbonic anhydrase (CA ... ) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular ... [L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure …
Matched Mixtures name: … Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide HCl and Timolol Maleate ... Dorzolamide Hydrochloride and Timolol Maleate …
Matched Categories: … Sulfur Compounds ... Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Dutasteride

Dutasteride is an oral synthetic 4-azasteroid commonly marketed under the trade name Avodart. It is a novel dual 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and irreversible manner. Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary hormonal...
Approved
Investigational
Matched Synonyms: … α,α,α,α',α',α'-hexafluoro-3-oxo-4-aza-5α-androst-1-ene-17β-carboxy-2',5'-xylidide …
Matched Description: … 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and ... hormonal mediator that plays a role in the development and enlargement of the prostate gland. ... [A1909] Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary …
Matched Mixtures name: … Dutasteride and tamsulosin hydrochloride ... Dutasteride and Tamsulosin Hydrochloride ... Dutasteride and tamsulosin hydrochloride …
Matched Categories: … tamsulosin and dutasteride ... Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists …

CAR BCMA-CS1

CAR BCMA-CS1 is a lentiviral transfected chimeric antigen receptor (CAR) T-cell therapy modified to target B-cell maturation antigen and CS1.
Investigational
Matched Name: … CAR BCMA-CS1 …
Matched Description: … B-cell maturation antigen and CS1. ... CAR BCMA-CS1 is a lentiviral transfected chimeric antigen receptor (CAR) T-cell therapy modified to target …

Idecabtagene vicleucel

Multiple myeloma is a cancer where plasma cells rapidly divide out of control. These cancerous cells generally express the B-cell maturation antigen, while it is rarely expressed on non-cancerous cells. Multiple myeloma is typically treated with an immunomodulatory agent like lenalidomide, a proteasome inhibitor like bortezomib, or an anti-CD38 monoclonal...
Approved
Matched Synonyms: … Anti-BCMA CAR T cell …
Matched Description: … therapy like [axicabtagene ciloleucel] and [brexucabtagene autoleucel]. ... [A232558,A232563,L32858] These therapies involve extracting and genetically manipulating T-cells from ... vicleucel includes an anti-B-cell maturation antigen scFv-targeting domain, CD3ζ T-cell activation domain, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents ... Receptors, Cytoplasmic and Nuclear …

Al-6619, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Hydroxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide]

Experimental
Matched Name: … Al-6619, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Hydroxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide …
Displaying drugs 976 - 1000 of 1077 in total