Displaying drugs 976 - 1000 of 1080 in total
Letrozole
Letrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990.[A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like exemestane and anastrozole, meaning it does not significantly affect cortisol, aldosterone, and thyroxine. Letrozole was granted FDA approval on 25 July 1997.
Approved
Investigational
Matched Description: … ], meaning it does not significantly affect cortisol, aldosterone, and thyroxine. ... [A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … LETROZOL AMAROX 2.5MG FTA …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … LETROZOL AMAROX 2.5MG FTA …
SARS-CoV-2 virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer (B.1.351-B.1.1.7 strains)
Bimervax is an adjuvanted non-mRNA COVID-19 vaccine utilizing a SARS-CoV-2 recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer. It is intended to elicit protection against Omicron XBB.1.5, one of the dominant circulating SARS-CoV-2 subvariants in 2023. It is produced using recombinant DNA technology in CHO cell lines and...
Approved
Matched Synonyms: … SARS-CoV-2 virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer – B.1.351 …
Matched Name: … SARS-CoV-2 virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer (B.1.351 …
Matched Description: … [A262551] It is produced using recombinant DNA technology in CHO cell lines and is marketed by Hipra ... Bimervax is an adjuvanted non-mRNA COVID-19 vaccine utilizing a SARS-CoV-2 recombinant spike (S) protein …
Matched Name: … SARS-CoV-2 virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer (B.1.351 …
Matched Description: … [A262551] It is produced using recombinant DNA technology in CHO cell lines and is marketed by Hipra ... Bimervax is an adjuvanted non-mRNA COVID-19 vaccine utilizing a SARS-CoV-2 recombinant spike (S) protein …
Mecasermin rinfabate
Mecasermin rinfabate is approved for severe primary insulin-like growth factor (IGF) deficiency or in patients with GH gene deletion who have developed antibodies to growth hormone (GH) . Mecasermin rinfabate is similar to DB01277 in that both drugs contain recombinant DNA origin insulin-like growth factor 1 (IGF-1). Mecasermin rinfabate however,...
Approved
Matched Synonyms: … Recombinant human insulin-like growth factor-I/insulin-like growth factor binding protein-3 …
Matched Description: … The binding of IGF-1 to IGFBP-3 is said to extend the half life and reduce the clearance of IGF-1 in ... patients with growth hormone resistant syndromes and low levels of IGFBP-3 though this may represent ... Mecasermin rinfabate however, is already bound to recombinant DNA origin insulin-like growth factor binding protein …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Anterior Pituitary Lobe Hormones and Analogues ... Somatropin and Somatropin Agonists ... Sex Hormones and Insulins …
Matched Description: … The binding of IGF-1 to IGFBP-3 is said to extend the half life and reduce the clearance of IGF-1 in ... patients with growth hormone resistant syndromes and low levels of IGFBP-3 though this may represent ... Mecasermin rinfabate however, is already bound to recombinant DNA origin insulin-like growth factor binding protein …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Anterior Pituitary Lobe Hormones and Analogues ... Somatropin and Somatropin Agonists ... Sex Hormones and Insulins …
Simethicone
Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination. It has a favourable safety profile as it is not systemically absorbed. Simethicone has been in use since the 1940s but was granted FDA approval in 1952.
Approved
Matched Description: … [A228308]
Simethicone has been in use since the 1940s[A228303] but was granted FDA approval in 1952 …
Matched Mixtures name: … Gelusil Antacid and Anti-gas ... PROMAG FRUITY (RASA ANGGUR) …
Matched Products: … VELGASTIN BLAEHUNGEN SUS …
Matched Mixtures name: … Gelusil Antacid and Anti-gas ... PROMAG FRUITY (RASA ANGGUR) …
Matched Products: … VELGASTIN BLAEHUNGEN SUS …
Bersanlimab
Bersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule 1 (ICAM-1).
Investigational
Matched Synonyms: … Immunoglobulin g1-lambda, anti-(homo sapiens icam1(intercellular adhesion molecule 1, icam-1, cd54)), …
Loncastuximab tesirine
Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients who have undergone prior systemic therapies with limited success. Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases and improve survival. On April 23 2021, the Food and Drug Administration granted accelerated...
Approved
Investigational
Matched Synonyms: … Humanized monoclonal immunoglobulin G1 antibody directed against human CD19 conjugated to SG3199 through A protease …
Matched Description: … and improve survival. ... Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients ... [A234439] Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Proteins ... Blood Proteins …
Matched Description: … and improve survival. ... Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients ... [A234439] Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Proteins ... Blood Proteins …
Torapsel
Torapsel has been used in trials studying the prevention of Ischemia Reperfusion Injury.
Investigational
Matched Synonyms: … 42-89-GLYCOPROTEIN (HUMAN CLONE PMT21:PL85 P-SELECTIN GLYCOPROTEIN LIGAND-1) FUSION PROTEIN WITH IMMUNOGLOBULIN …
Matched Description: … Torapsel has been used in trials studying the prevention of Ischemia Reperfusion Injury. …
Matched Description: … Torapsel has been used in trials studying the prevention of Ischemia Reperfusion Injury. …
Zafiride
Zafiride is a human tumor necrosis factor coupled to the C terminus of CNGRCG peptide.
Investigational
Matched Synonyms: … Tumour-homing-peptide-tumour-necrosis-factor-alpha-fusion-protein …
Elotuzumab
Elotuzumab is a humanized IgG1 (Immunoglobulin G) monoclonal antibody indicated in combination with lenalidomide and dexamethasone for the treatment of patients with multiple myeloma who have received one to three prior therapies. Elotuzumab targets SLAMF7, also known as Signaling Lymphocytic Activation Molecule Family member 7, a cell surface glycoprotein. Elotuzumab...
Approved
Matched Synonyms: … Immunoglobulin G1, anti-(human protein CS1) (human-mouse HuLuc63 heavy chain), disulfide with human-mouse …
Matched Description: … a humanized IgG1 (Immunoglobulin G) monoclonal antibody indicated in combination with lenalidomide and ... Food and Drug Administration. ... complementary determining regions (CDR) of the mouse antibody, MuLuc63, grafted onto human IgG1 heavy and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Proteins ... Blood Proteins …
Matched Description: … a humanized IgG1 (Immunoglobulin G) monoclonal antibody indicated in combination with lenalidomide and ... Food and Drug Administration. ... complementary determining regions (CDR) of the mouse antibody, MuLuc63, grafted onto human IgG1 heavy and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Proteins ... Blood Proteins …
Nebivolol
Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than atenolol, propranolol, or pindolol. Nebivolol and other beta...
Approved
Investigational
Matched Description: … Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other ... [A182579] Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure ... [A182579] Nebivolol and other beta blockers are generally not first line therapies as many patients are …
Matched Categories: … Beta Blocking Agents and Thiazides ... Beta blocking agents and calcium channel blockers ... valsartan and nebivolol ... nebivolol and amlodipine ... nebivolol and thiazides …
Matched Products: … NEBIVOLOLO AMAROX …
Matched Categories: … Beta Blocking Agents and Thiazides ... Beta blocking agents and calcium channel blockers ... valsartan and nebivolol ... nebivolol and amlodipine ... nebivolol and thiazides …
Matched Products: … NEBIVOLOLO AMAROX …
Tilavonemab
Investigational
Matched Synonyms: … Immunoglobulin g4, anti-(human tau protein) (human-mus musculus monoclonal pr-1649264 .gamma.4-chain) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
EDIT-101
EDIT-101 is a recombinant adeno-associated virus pseudotyped with serotype 5 viral capsid encoding CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats associated protein 9) gene editing constructs.
Investigational
Matched Synonyms: … viral capsid encoding CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats associated protein …
Matched Description: … viral capsid encoding CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats associated protein …
Matched Description: … viral capsid encoding CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats associated protein …
Ozanezumab
Ozanezumab has been used in trials studying the treatment of Multiple Sclerosis, Amyotrophic Lateral Sclerosis, and Multiple Sclerosis, Relapsing-Remitting.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(PROTEIN NOGO-A) (HUMAN-MUS MUSCULUS MONOCLONAL HEAVY CHAIN), DISULFIDE WITH …
Matched Description: … Sclerosis, and Multiple Sclerosis, Relapsing-Remitting. ... Ozanezumab has been used in trials studying the treatment of Multiple Sclerosis, Amyotrophic Lateral …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Matched Description: … Sclerosis, and Multiple Sclerosis, Relapsing-Remitting. ... Ozanezumab has been used in trials studying the treatment of Multiple Sclerosis, Amyotrophic Lateral …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
NBL-015
Investigational
Matched Synonyms: … Fully human monoclonal IgG1 antibody against the type 2 isoform of human Claudin 18 protein (Claudin …
Influenza A virus A/Slovenia/2903/2015 (H1N1) live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Slovenia/2903/2015 (H1N1) live (attenuated) antigen …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …
Influenza A virus A/Hawaii/66/2019 (H1N1) live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Hawaii/66/2019 (H1N1) live (attenuated) antigen …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …
Influenza A virus A/South Australia/55/2014 live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/South Australia/55/2014 live (attenuated) antigen …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …
Influenza A virus A/Norway/16606/2021 (H3N2) live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A virus A/Norway/16606/2021 (H3N2) live (attenuated) antigen …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …
Matched Categories: … Live Attenuated Influenza A Virus Vaccine …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …
Matched Categories: … Live Attenuated Influenza A Virus Vaccine …
Influenza B virus B/Washington/02/2019 live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza B virus B/Washington/02/2019 live (attenuated) antigen …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …
Influenza A virus A/Switzerland/9715293/2013 (H3N2) live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Switzerland/9715293/2013 (H3N2) live (attenuated) antigen …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …
Influenza A virus A/Kansas/14/2017 (H3N2) live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Kansas/14/2017 (H3N2) live (attenuated) antigen …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …
INVAC-1
INVAC-1 is under investigation in clinical trial NCT03265717 (DNA Plasmid Encoding a Modified Human Telomerase Reverse Transcriptase (Htert), Invac-1 in Chronic Lymphocytic Leukemia).
Investigational
Matched Synonyms: … plasmid vaccine construct encoding ubiquitin-human telomerase reverse transcriptase (htert) fusion protein …
Bepranemab
Bepranemab is a recombinant humanized Igg4P monoclonal antibody directed against human Tau.
Investigational
Matched Synonyms: … Immunoglobulin g4 (226-proline), anti-(human tau protein) (human-rattus norvegicus monoclonal ucb0107 …
Fazirsiran
Investigational
Matched Synonyms: … Double stranded oligomer ADS-001 RNA interference-based liver targeted therapeutic …
Neisseria meningitidis serogroup B recombinant LP2086 B01 protein variant antigen
Neisseria meningitidis serogroup b recombinant lp2086 b01 protein variant antigen is a sterile vaccine for intramuscular injection indicated for the active immunization to prevent invasive disease caused by Neisseria meningitidis serogroup B. It is contained in the suspension of Trumenba, which is a vaccine is composed of two recombinant lipidated...
Approved
Matched Name: … Neisseria meningitidis serogroup B recombinant LP2086 B01 protein variant antigen …
Matched Description: … (A05 and B01, respectively). ... (fHBP) variants from N. meningitidis serogroup B, one from fHBP subfamily A and one from subfamily B ... Neisseria meningitidis serogroup b recombinant lp2086 b01 protein variant antigen is a sterile vaccine …
Matched Description: … (A05 and B01, respectively). ... (fHBP) variants from N. meningitidis serogroup B, one from fHBP subfamily A and one from subfamily B ... Neisseria meningitidis serogroup b recombinant lp2086 b01 protein variant antigen is a sterile vaccine …
Displaying drugs 976 - 1000 of 1080 in total