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Displaying drugs 976 - 1000 of 1327 in total

Ticagrelor

Ticagrelor, or AZD6140, was first described in the literature in 2003.[A204170,A2903] Ticagrelor is an ADP derivative developed for its P2Y12 receptor antagonism. Unlike clopidogrel, ticagrelor is not a prodrug. It is marketed by Astra Zeneca as Brilinta in the US and Brilique or Possia in the EU, . Ticagrelor was...
Approved
Matched Description: … [A2903] It is marketed by Astra Zeneca as Brilinta in the US[L14201] and Brilique or Possia in the EU …
Matched Categories: … Blood and Blood Forming Organs ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … BRILINTA 90MG FILM-COATED TABLET ... ABRİLOR 60 MG FİLM KAPLI TABLET, 56 ADET ... ALMINDA (FILM-COATED TABLETS 90 MG) …

Idebenone

Idebenone is a synthetic analogue of ubiquinone (also known as Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC). It has been proposed that by interacting with the ETC, idebenone increases ATP production required for mitochondrial function, reduces free radicals, inhibits lipid peroxidation, and...
Approved
Investigational
Matched Description: … Idebenone is a synthetic analogue of ubiquinone (also known as Coenzyme Q10), a vital cell antioxidant and ... consequently protects the lipid membrane and mitochondria from oxidative damage [A19768]. ... production required for mitochondrial function, reduces free radicals, inhibits lipid peroxidation, and …
Matched Mixtures name: … BERMAXIN 90/10/5 MG FILM TABLET ,FILM TABLET, 28 ADET ... BERMAXIN 90/10/5 MG FILM TABLET ,FILM TABLET, 84 ADET ... EVERON 90/5 MG FILM KAPLI TABLET ,50 TABLET …
Matched Categories: … Enzymes and Coenzymes ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … IDEBEX 45 MG FILM KAPLI TABLET ,90 FILM KAPLI TABLET ... IDEBEX 90 MG FILM KAPLI TABLET ,90 FILM KAPLI TABLET ... IDEBEX 45 MG FILM KAPLI TABLET ,FILM KAPLI TABLET, 30 ADET …

Dapoxetine

Dapoxetine is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation. In a phase II proof-of-concept study conducted by PPD, dapoxetine demonstrated a statistically significant increase in ejaculatory latency when compared to placebo. Alza submitted a NDA to the FDA for dapoxetine for the treatment of premature ejaculation...
Investigational
Matched Mixtures name: … DAPOXIL 30/50 MG FILM KAPLI TABLET,18 FILM KAPLI TABLET ... DAPOKSEL 30 MG/50 MG FILM TABLET ,3 FILM TABLET ... DAPOKSEL 30 MG/50 MG FILM TABLET ,6 FILM TABLET …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … DAPIGRA 30 MG FILM TABLET ,3 FILM TABLET ... DAPIGRA 30 MG FILM TABLET ,6 FILM TABLET ... DAPIGRA 60 MG FILM TABLET ,3 FILM TABLET …

Erdafitinib

In early April of 2019, the US FDA approved Janssen Pharmaceutical Companies' brand name Balversa (erdafitinib) as the first-ever fibroblast growth factor receptor (FGFR) kinase inhibitor indicated for patients with locally advanced or metastatic urothelial carcinoma, with susceptible FGFR3 or FGFR2 genetic alterations, that has progressed during or following platinum-containing...
Approved
Investigational
Matched Description: … for patients with metastatic bladder cancer, which demonstrates the development of more personalized and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … BALVERSA FILM-COATED TABLETS 3MG ... BALVERSA FILM-COATED TABLETS 5MG ... BALVERSA FILM-COATED TABLETS 4MG …

Brivaracetam

Brivaracetam is a racetam derivative of levetiracetam used in the treatment of partial-onset seizures. Brivaracetam binds SV2A with 20 times higher affinity than levetiracetam . It is available under the brand name Briviact made by UCB. Briviact received FDA approval on February 19, 2016 .
Approved
Investigational
Matched Products: … BRIVIACT 10 MG FILM KAPLI TABLET ,14 FILM KAPLI TABLET ... BRIVIACT 10 MG FILM KAPLI TABLET ,168 FILM KAPLI TABLET ... BRIVIACT 10 MG FILM KAPLI TABLET ,56 FILM KAPLI TABLET …

Macitentan

Macitentan is a dual endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH). It was first approved by the FDA in 2013. Macitentan differs from its predecessor bosentan in part due to its lower risk of hepatotoxicity. A combination product (Opsynvi) comprising macitentan and tadalafil was approved...
Approved
Matched Description: … A combination product (Opsynvi) comprising macitentan and [tadalafil] was approved in Canada in October ... [L39105] It was subsequently approved by the FDA in March 2024.[L50622] …
Matched Categories: … macitentan and tadalafil …
Matched Products: … OPSUMIT FILM-COATED TABLET 10MG ... Opsumit 10mg Film-Coated Tablets ... Opsumit ® 10mg Film-Coated Tablets …

Selexipag

Selexipag was approved by the United States FDA on December 22, 2015 for the treatment of pulmonary arterial hypertension (PAH) to delay disease progression and reduce risk of hospitalization. PAH is a relatively rare disease with usually a poor prognosis requiring more treatment options to prolong long-term outcomes. Marketed by...
Approved
Matched Description: … December 22, 2015 for the treatment of pulmonary arterial hypertension (PAH) to delay disease progression and ... Marketed by Actelion Pharmaceuticals under brand name Uptravi, selexipag and its active metabolite, ACT ... act as agonists of the prostacyclin receptor to increase vasodilation in the pulmonary circulation and …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … UPTRAVI FILM-COATED TABLET 200MCG ... UPTRAVI FILM-COATED TABLETS 400MCG ... UPTRAVI FILM-COATED TABLETS 600MCG …

Maraviroc

Maraviroc (brand-named Selzentry, or Celsentri outside the U.S.) is a chemokine receptor antagonist drug developed by the drug company Pfizer that is designed to act against HIV by interfering with the interaction between HIV and CCR5. It was originally labelled as UK-427857 during development but was assigned the Maraviroc name...
Approved
Investigational
Matched Description: … company Pfizer that is designed to act against HIV by interfering with the interaction between HIV and …
Matched Products: … Celsentri Film-Coated Tablet 300mg ... Celsentri Film-Coated Tablet 150mg ... CELSENTRI 150 MG FILM KAPLI TABLET ,180 ADET …

Etodolac

Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.
Approved
Investigational
Vet approved
Matched Description: … It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis. ... Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic …
Matched Mixtures name: … ETOTİO 400MG/8MG FİLM KAPLI TABLET, FİLM TABLET, 14 ADET ... ETOTIO 400 MG/8 MG FILM TABLET, 20 ADET ... ETOFAM 400MG/20MG FİLM KAPLI TABLET, 20 ADET …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … BARCA 500 MG FILM TABLET, 14 ADET ... CIRRINAL 200 MG FILM TABLET, 20 ADET ... EDOLAR 600 MG FILM TABLET, 10 ADET …

Erlotinib

Erlotinib is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase that is used in the treatment of non-small cell lung cancer, pancreatic cancer and several other types of cancer. It is typically marketed under the trade name Tarceva. Erlotinib binds to the epidermal growth factor receptor (EGFR)...
Approved
Investigational
Matched Description: … EGFR) tyrosine kinase that is used in the treatment of non-small cell lung cancer, pancreatic cancer and ... , which is a mutant form of tyrosine kinase JAK2 found in most patients with polycythemia vera (PV) and ... This finding introduces the potential use of erlotinib in the treatment of JAK2V617F-positive PV and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … TARCEVA FILM-COATED TABLET 25 MG ... TARCEVA FILM-COATED TABLET 100 MG ... TARCEVA FILM-COATED TABLET 150 MG …

Edoxaban

Edoxaban is a member of the Novel Oral Anti-Coagulants (NOACs) class of drugs, and is a rapidly acting, oral, selective factor Xa inhibitor. By inhibiting factor Xa, a key protein in the coagulation cascade, edoxaban prevents the stepwise amplification of protein factors needed to form blood clots. It is indicated...
Approved
Matched Description: … INR testing, and numerous drug-drug and drug-food interactions. ... atrial fibrillation (NVAF) and for the treatment of deep vein thrombosis (DVT) and pulmonary embolism ... Edoxaban is a member of the Novel Oral Anti-Coagulants (NOACs) class of drugs, and is a rapidly acting …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … LIXIANA FILM-COATED TABLET 30 MG ... LIXIANA FILM-COATED TABLET 60 MG ... LIXIANA FILM-COATED TABLET 15 MG …

Favipiravir

Discovered by Toyama Chemical Co., Ltd. in Japan, favipiravir is a modified pyrazine analog that was initially approved for therapeutic use in resistant cases of influenza.[A191688,A191721] The antiviral targets RNA-dependent RNA polymerase (RdRp) enzymes, which are necessary for the transcription and replication of viral genomes.[A191688,A191772,A191775] Not only does favipiravir inhibit...
Approved
Investigational
Matched Description: … antiviral targets RNA-dependent RNA polymerase (RdRp) enzymes, which are necessary for the transcription and ... [A191688,A191772,A191775] Not only does favipiravir inhibit replication of influenza A and B, but ... the drug has shown promise in the treatment of avian influenza, and may be an alternative option for …
Matched Products: … AVIGAN Film-Coated Tablets 200mg (Favipiravir) ... KOVİPİR 200 MG FİLM KAPLI TABLET, 40 ADET ... FAVİRA 200 MG FİLM KAPLI TABLET, 40 ADET …

Escitalopram

Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic citalopram. It is used to restore serotonergic function in the treatment of depression and anxiety.[L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and is responsible for the vast majority of citalopram’s clinical activity, with...
Approved
Matched Description: … Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic [citalopram ... [A185420] It is used to restore serotonergic function in the treatment of depression and anxiety. ... L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and …
Matched Products: … Mar-escitalopram ... ANZYL 10 MG FILM TABLET ,56 FILM TABLET ... ANZYL 20 MG FILM TABLET ,56 FILM TABLET …

Eltrombopag

Eltrombopag is used to treat low blood platelet counts in adults with chronic immune (idiopathic) thrombocytopenia (ITP), when certain other medicines, or surgery to remove the spleen, have not worked well enough. ITP is a condition that may cause unusual bruising or bleeding due to an abnormally low number of...
Approved
Matched Description: … thrombocytopenia (low blood platelet counts) in patients with chronic hepatitis C to allow them to initiate and …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … REVOLADE FILM-COATED TABLET 25MG ... REVOLADE FILM-COATED TABLET 50MG ... REVOLADE 12.5 MG FİLM TABLET, 14 ADET …

Gemifloxacin

Gemifloxacin is a quinolone antibacterial agent with a broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. It is available in oral formulations. Gemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase IV, which are...
Approved
Investigational
Matched Description: … broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and ... Gemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase …
Matched Products: … Factive film-coated tablet 320 mg ... ONFACT 320 MG FİLM TABLET, 5 ADET ... ONFACT 320 MG FİLM TABLET, 7 ADET …

2-Methyl-2-propanyl [(1S)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl]carbamate

Experimental
Matched Name: … 2-Methyl-2-propanyl [(1S)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl]carbamate …

Trametinib

Trametinib is an orally bioavailable mitogen-activated extracellular signal-regulated kinase 1 (MEK1) and MEK2 inhibitor.[A258298,A258293] It was first approved by the FDA in May 2013 for the treatment of melanoma. It was later approved by Health Canada on July 18, 2013 and by the European Commission on June 30, 2014. Trametinib...
Approved
Matched Description: … Trametinib is an orally bioavailable mitogen-activated extracellular signal-regulated kinase 1 (MEK1) and ... [A258298] It was later approved by Health Canada on July 18, 2013 [L45588] and by the European Commission ... currently approved to treat a variety of cancers with BRAF mutations, such as non-small cell lung cancer and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … MEKINIST FILM-COATED TABLETS 2MG ... Meqsel 2mg Film-Coated Tablet ... MEKINIST FILM-COATED TABLETS 0.5MG …

Tenofovir disoproxil

Tenofovir disoproxil fumarate (a prodrug of tenofovir), marketed by Gilead Sciences under the trade name Viread, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase inhibitors (nRTIs). This drug is prescribed in combination with other drugs for the management of HIV infection as well as for...
Approved
Investigational
Matched Mixtures name: … LAMIHOPE-T (LAMIVUDINE 300MG AND TENOFOVIR DISOPROXIL FUMARATE 300MG FILM-COATED TABLETS) ... FORSTAVIR-LE ( Efavirenz 600 mg, Lamivudine 300 mg and Tenofovir Disoproxil Fumarate 300 mg ) Film-coated ... TRUVADA 200 MG/245 MG FILM TABLET, 30 ADET …
Matched Categories: … Tenofovir and prodrugs ... lamivudine and tenofovir disoproxil ... tenofovir disoproxil and emtricitabine ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors ... lamivudine, tenofovir disoproxil and dolutegravir …
Matched Products: … TENVIR FILM-COATED TABLET ... VIRSOEM 245 MG FILM TABLET,30 ADET ... VIRSOEM 245 MG FILM TABLET, 90 ADET …

Al-6619, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Hydroxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide]

Experimental
Matched Name: … Al-6619, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Hydroxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide …

Al-6629, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Methoxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide]

Experimental
Matched Name: … Al-6629, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Methoxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide …

(3R)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide

Experimental
Matched Name: … 3R)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide …

Vortioxetine

Vortioxetine is an antidepressant medication indicated for the treatment of major depressive disorder (MDD). It is classified as a serotonin modulator and stimulator (SMS) as it has a multimodal mechanism of action towards the serotonin neurotransmitter system whereby it simultaneously modulates one or more serotonin receptors and inhibits the reuptake...
Approved
Investigational
Matched Description: … an antagonist of the 5-HT3, 5-HT1D, and 5-HT7 receptors. ... It is classified as a serotonin modulator and stimulator (SMS) as it has a multimodal mechanism of action ... serotonin neurotransmitter system whereby it simultaneously modulates one or more serotonin receptors and …
Matched Products: … Brintellix 5mg film-coated tablets ... Brintellix 15mg Film-coated Tablets ... Brintellix 20mg Film-coated Tablets …

Tofacitinib

Tofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function. It is approved by the FDA for treatment of moderate to severe rheumatoid arthritis that responds inadequately to methotrexate or in those who are intolerant to methotrexate....
Approved
Investigational
Matched Description: … treatment of moderate to severe rheumatoid arthritis that responds inadequately to methotrexate or in those who ... Known adverse effects include nausea and headache as well as more serious immunologic and hematological ... kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Xeljanz Film-Coated Tablets 5mg ... Tozib 5mg Film Coated Tablets ... JANTY 5 MG FİLM KAPLI TABLET, 56 ADET …

Spiramycin

Spiramycin is a primarily bacteriostatic macrolide antimicrobial agent with activity against Gram-positive cocci and rods, Gram-negative cocci and also Legionellae, mycoplasmas, chlamydiae, some types of spirochetes, Toxoplasma gondii and Cryptosporidium. Spiramycin is a 16-membered ring macrolide discovered in 1952 as a product of Streptomyces ambofaciens that has been available in...
Approved
Matched Description: … Toxoplasma gondii and Cryptosporidium. ... a primarily bacteriostatic macrolide antimicrobial agent with activity against Gram-positive cocci and ... Resistant organisms include Enterobacteria, pseudomonads, and moulds. …
Matched Mixtures name: … METİRASİN 1,5 MIU/250 MG FILM TABLET, 10 ADET ... METİRASİN 1,5 MIU/250 MG FILM TABLET, 14 ADET …
Matched Categories: … spiramycin and metronidazole ... Macrolides, Lincosamides and Streptogramins …
Matched Products: … FİLM KAPLI TABLET , 10 ADET ... FİLM KAPLI TABLET , 14 ADET ... SPRAMAX 1,5 MIU FİLM KAPLI TABLET, 10 ADET …

Baricitinib

Baricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. Overactive JAKs have been implicated in autoimmune disorders, such as rheumatoid arthritis. By inhibiting the actions of JAK1 and JAK2, baricitinib attenuates JAK-mediated inflammation and immune responses. Baricitinib was...
Approved
Investigational
Matched Description: … By inhibiting the actions of JAK1 and JAK2, baricitinib attenuates JAK-mediated inflammation and immune ... European Commission (EC) in February 2017 for the treatment of rheumatoid arthritis in adults [A248395] and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … UNAMİTY 4 MG FİLM KAPLI TABLET, 7 ADET ... OLUMIANT FILM-COATED TABLET 2MG ... OLUMIANT FILM-COATED TABLET 4MG …
Displaying drugs 976 - 1000 of 1327 in total