Displaying drugs 976 - 1000 of 2178 in total
TBI-223
TBI-223 is under investigation in clinical trial NCT06192160 (Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis).
Investigational
Matched Synonyms: … )-, METHYL ESTER ... CARBAMIC ACID, N-(((5S)-3-(3-FLUORO-4-(2-OXA-6-AZASPIRO(3.3)HEPT-6-YL)PHENYL)-2-OXO-5-OXAZOLIDINYL)METHYL …
Mycophenolate mofetil
Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified as a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH). This drug is an immunosuppressant combined with drugs such as Cyclosporine and corticosteroids to prevent organ rejection after hepatic, renal, and cardiac transplants. It is...
Approved
Investigational
Matched Synonyms: … 2-morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate …
Matched Iupac: … 2-(morpholin-4-yl)ethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex …
Matched Description: … [A180826] The new semi-synthetic 2-morpholinoethyl ester of MPA was synthesized to avoid the gastrointestinal ... to prevent organ rejection after hepatic, renal, and cardiac transplants. ... Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified …
Matched Categories: … Mycophenolic Acid and Prodrugs …
Matched Iupac: … 2-(morpholin-4-yl)ethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex …
Matched Description: … [A180826] The new semi-synthetic 2-morpholinoethyl ester of MPA was synthesized to avoid the gastrointestinal ... to prevent organ rejection after hepatic, renal, and cardiac transplants. ... Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified …
Matched Categories: … Mycophenolic Acid and Prodrugs …
Hypromellose
Hypromellose, or hydroxypropyl methylcellulose (HPMC) , is a semisynthetic, inert, and viscoelastic polymer that forms a colloid solution when dissolved in water. It acts as a thickening agent, coating polymer, bioadhesive, solubility enhancer in solid dispersions, and binder in the process of granulation and in modified release formulations . It...
Approved
Matched Synonyms: … Cellulose hydroxypropyl methyl ether ... Cellulose, 2-hydroxypropyl methyl ether …
Matched Description: … Hypromellose, or hydroxypropyl methylcellulose (HPMC) [L1812], is a semisynthetic, inert, and viscoelastic ... binder in the process of granulation and in modified release formulations [A24840]. ... acts as a thickening agent, coating polymer, bioadhesive, solubility enhancer in solid dispersions, and …
Matched Mixtures name: … Rohto Sun and Sport …
Matched Description: … Hypromellose, or hydroxypropyl methylcellulose (HPMC) [L1812], is a semisynthetic, inert, and viscoelastic ... binder in the process of granulation and in modified release formulations [A24840]. ... acts as a thickening agent, coating polymer, bioadhesive, solubility enhancer in solid dispersions, and …
Matched Mixtures name: … Rohto Sun and Sport …
Benoxaprofen
The use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets from the market on August 5, 1982.
Approved
Withdrawn
Matched Synonyms: … 2-(4-chlorophenyl)-α-methyl-5-benzoxazoleacetic acid ... 2-(p-chlorophenyl)-α-methyl-5-benzoxazoleacetic acid ... 2-(4-Chlorophenyl)-alpha-methyl-5-benzoxazoleacetic acid …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Lymecycline
Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and other susceptible bacterial infections.[L13880,L13883] It has been proven a cost-effective alternative to treatment with minocycline with comparable safety and efficacy. Lymecycline was initially discovered in 1961. It is marketed by Galderma and used in the UK...
Approved
Investigational
Matched Synonyms: … 2-naphthacenecarboxamido)methyl)lysine ... N2-(((+)-5-Amino-5-carboxypentylamino)methyl)tetracycline ... carboxypentylaminomethyl)-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl …
Matched Iupac: … ,5,5a,6,11,12a-octahydrotetracen-2-yl]formamido}methyl)amino]-2-aminohexanoic acid ... (2S)-6-[({[(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a …
Matched Description: … Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and ... has been proven a cost-effective alternative to treatment with [minocycline] with comparable safety and ... It is marketed by Galderma and used in the UK as well as New Zealand in addition to other countries. …
Matched Iupac: … ,5,5a,6,11,12a-octahydrotetracen-2-yl]formamido}methyl)amino]-2-aminohexanoic acid ... (2S)-6-[({[(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a …
Matched Description: … Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and ... has been proven a cost-effective alternative to treatment with [minocycline] with comparable safety and ... It is marketed by Galderma and used in the UK as well as New Zealand in addition to other countries. …
Rifapentine
Rifapentine is an antibiotic drug used in the treatment of tuberculosis. It inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme.
Approved
Investigational
Matched Synonyms: … 3-(((4-Cyclopentyl-1-piperazinyl)imino)methyl)rifamycin …
Matched Iupac: … (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-26-[(E)-[(4-cyclopentylpiperazin-1-yl)imino]methyl]-2,15,17,27,29 …
Matched Iupac: … (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-26-[(E)-[(4-cyclopentylpiperazin-1-yl)imino]methyl]-2,15,17,27,29 …
Hispidulin
Hispidulin (4',5,7-trihydroxy-6-methoxyflavone) is a potent benzodiazepine (BZD) receptor ligand with positive allosteric properties .
Experimental
Matched Synonyms: … Scutellarein 6-methyl ether …
Benzoctamine
Benzoctamine is a drug with two main uses. It can be used as a sedative which does not depress the respiratory system, but rather stimulates it. It can also be used as an anxiolytic with the same efficacy as chlordiazepoxide for treating anxiety neurosis.
Experimental
Matched Synonyms: … N-Methyl-9,10-ethanoanthracene-9(10H)-methanamine …
Matched Iupac: … methyl({tetracyclo[6.6.2.0²,⁷.0⁹,¹⁴]hexadeca-2,4,6,9,11,13-hexaen-1-yl}methyl)amine …
Matched Iupac: … methyl({tetracyclo[6.6.2.0²,⁷.0⁹,¹⁴]hexadeca-2,4,6,9,11,13-hexaen-1-yl}methyl)amine …
Viloxazine
Viloxazine is a selective norepinephrine reuptake inhibitor. For decades, an immediate-release formulation of viloxazine has been used in Europe as an antidepressant. It was first approved in the UK in 1974; however, the immediate-release formulation was discontinued due to business reasons unrelated to drug safety and efficacy. In the US,...
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-((2-Ethoxyphenoxy)methyl)morpholine …
Matched Iupac: … 2-[(2-ethoxyphenoxy)methyl]morpholine …
Matched Description: … the immediate-release formulation was discontinued due to business reasons unrelated to drug safety and ... designation in 1984 under the brand name CATATROL: while this product was intended to treat cataplexy and …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Monoamine Oxidase Inhibitors ... Monoamine Oxidase A Inhibitors ... Monoamine Oxidase B Inhibitors …
Matched Iupac: … 2-[(2-ethoxyphenoxy)methyl]morpholine …
Matched Description: … the immediate-release formulation was discontinued due to business reasons unrelated to drug safety and ... designation in 1984 under the brand name CATATROL: while this product was intended to treat cataplexy and …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Monoamine Oxidase Inhibitors ... Monoamine Oxidase A Inhibitors ... Monoamine Oxidase B Inhibitors …
Emetonium iodide
Experimental
Matched Synonyms: … Ethylbenzhydramine methyl iodide …
Matched Categories: … Alimentary Tract and Metabolism ... Synthetic Anticholinergics, Quaternary Ammonium Compounds …
Matched Categories: … Alimentary Tract and Metabolism ... Synthetic Anticholinergics, Quaternary Ammonium Compounds …
N-Methyl-Pyridoxal-5'-Phosphate
Experimental
Matched Name: … N-Methyl-Pyridoxal-5'-Phosphate …
Matched Iupac: … 4-formyl-3-hydroxy-1,2-dimethyl-5-[(phosphonooxy)methyl]pyridin-1-ium …
Matched Iupac: … 4-formyl-3-hydroxy-1,2-dimethyl-5-[(phosphonooxy)methyl]pyridin-1-ium …
5'-S-methyl-5'-thioadenosine
Experimental
Matched Synonyms: … S-Methyl-5'-thioadenosine ... 9-(5-S-methyl-5-thio-β-D-ribofuranosyl)-9H-purin-6-amine …
Matched Name: … 5'-S-methyl-5'-thioadenosine …
Matched Iupac: … (2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-[(methylsulfanyl)methyl]oxolane-3,4-diol …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Nucleic Acids, Nucleotides, and Nucleosides ... Nucleic Acid Synthesis Inhibitors …
Matched Name: … 5'-S-methyl-5'-thioadenosine …
Matched Iupac: … (2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-[(methylsulfanyl)methyl]oxolane-3,4-diol …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Nucleic Acids, Nucleotides, and Nucleosides ... Nucleic Acid Synthesis Inhibitors …
3,5,6,8-Tetramethyl-N-Methyl Phenanthrolinium
Experimental
Matched Name: … 3,5,6,8-Tetramethyl-N-Methyl Phenanthrolinium …
[[N-(Benzyloxycarbonyl)Amino]Methyl]Phosphate
Experimental
Matched Name: … [[N-(Benzyloxycarbonyl)Amino]Methyl]Phosphate …
Matched Iupac: … ({[(benzyloxy)carbonyl]amino}methyl)phosphonic acid …
Matched Iupac: … ({[(benzyloxy)carbonyl]amino}methyl)phosphonic acid …
4-Methyl-5-Hydroxyethylthiazole Phosphate
Experimental
Matched Name: … 4-Methyl-5-Hydroxyethylthiazole Phosphate …
Matched Iupac: … [2-(4-methyl-1,3-thiazol-5-yl)ethoxy]phosphonic acid …
Matched Iupac: … [2-(4-methyl-1,3-thiazol-5-yl)ethoxy]phosphonic acid …
3,4-Dihydro-5-Methyl-Isoquinolinone
Experimental
Matched Name: … 3,4-Dihydro-5-Methyl-Isoquinolinone …
Matched Iupac: … 5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one …
Matched Iupac: … 5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one …
N-Methyl-N-(Methylbenzyl)Formamide
Experimental
Matched Name: … N-Methyl-N-(Methylbenzyl)Formamide …
Matched Iupac: … N-methyl-N-[(1S)-1-phenylethyl]formamide …
Matched Iupac: … N-methyl-N-[(1S)-1-phenylethyl]formamide …
S-METHYL-4,5,6,7-TETRABROMO-BENZIMIDAZOLE
Experimental
Matched Name: … S-METHYL-4,5,6,7-TETRABROMO-BENZIMIDAZOLE …
Masitinib
Masitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in dogs. It has been available in Europe since 2009, under the brand name Masivet. In the USA it is distributed under the name Kinavet and has been available for veterinaries since 2011.
Investigational
Vet approved
Matched Synonyms: … 4-((4-METHYLPIPERAZIN-1-YL)METHYL)-N-(4-METHYL-3-((4-PYRIDIN-3-YL-1,3-THIAZOL-2-YL)AMINO)PHENYL)BENZAMIDE …
Matched Iupac: … N-(4-methyl-3-{[4-(pyridin-3-yl)-1,3-thiazol-2-yl]amino}phenyl)-4-[(4-methylpiperazin-1-yl)methyl]benzamide …
Matched Description: … In the USA it is distributed under the name Kinavet and has been available for veterinaries since 2011 …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … N-(4-methyl-3-{[4-(pyridin-3-yl)-1,3-thiazol-2-yl]amino}phenyl)-4-[(4-methylpiperazin-1-yl)methyl]benzamide …
Matched Description: … In the USA it is distributed under the name Kinavet and has been available for veterinaries since 2011 …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Tenofovir amibufenamide
Investigational
Matched Synonyms: … Alanine, n-((s)-(((1r)-2-(6-amino-9h-purin-9-yl)-1-methylethoxy)methyl)phenoxyphosphinyl)-2-methyl-, …
Permethrin
A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid.
Approved
Investigational
Matched Synonyms: … (3-Phenoxyphenyl)methyl (±)-cis,trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate ... 3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropane carboxylic acid, (3-phenoxyphenyl) methyl ester …
Matched Iupac: … (3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate …
Matched Description: … A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. …
Matched Categories: … Synthetic Compounds ... Antiparasitic Products, Insecticides and Repellents ... Scabicides and Pediculicides ... Scabicides, Insecticides and Repellents …
Matched Iupac: … (3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate …
Matched Description: … A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. …
Matched Categories: … Synthetic Compounds ... Antiparasitic Products, Insecticides and Repellents ... Scabicides and Pediculicides ... Scabicides, Insecticides and Repellents …
ABT-737
An inhibitor of members of the Bcl‑2 family of apoptosis regulators.
Investigational
Matched Synonyms: … -1-((phenylthio)methyl)propyl)amino)-3-nitrophenyl)sulfonyl)- ... Benzamide, 4-(4-((4'-chloro(1,1'-biphenyl)-2-yl)methyl)-1-piperazinyl)-n-((4-(((1r)-3-(dimethylamino) …
Matched Iupac: … 4-[4-({4'-chloro-[1,1'-biphenyl]-2-yl}methyl)piperazin-1-yl]-N-(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl …
Matched Iupac: … 4-[4-({4'-chloro-[1,1'-biphenyl]-2-yl}methyl)piperazin-1-yl]-N-(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl …
Displaying drugs 976 - 1000 of 2178 in total