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Displaying drugs 10001 - 10025 of 12080 in total

GDC-0810

ARN-810 has been used in trials studying the basic science and treatment of Breast Cancer.
Investigational
Matched Iupac: … (2E)-3-{4-[(1E)-2-(2-chloro-4-fluorophenyl)-1-(1H-indazol-5-yl)but-1-en-1-yl]phenyl}prop-2-enoic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Tetrahydrouridine

Tetrahydrouridine has been used in trials studying the treatment of Neoplasms, Lung Neoplasms, Breast Neoplasms, Sickle Cell Disease, and Head and Neck Cancer, among others.
Investigational
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Toreforant

Toreforant has been used in trials studying the treatment of Asthma, Psoriasis, Hepatic Impairment, and Rheumatoid Arthritis.
Investigational
Matched Iupac: … 5-(4,6-dimethyl-1H-1,3-benzodiazol-2-yl)-4-methyl-N-[3-(1-methylpiperidin-4-yl)propyl]pyrimidin-2-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

DA-6886

DA-6886 has been used in trials studying the treatment of Irritable Bowel Syndrome.
Investigational
Matched Iupac: … 4-amino-5-chloro-2-methoxy-N-({1-[3-(1H-1,2,3-triazol-1-yl)propyl]piperidin-4-yl}methyl)benzamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Lavoltidine

Lavoltidine has been used in trials studying the diagnostic of Reflux, Gastroesophageal and Gastroesophageal Reflux Disease.
Investigational
Matched Iupac: … {1-methyl-5-[(3-{3-[(piperidin-1-yl)methyl]phenoxy}propyl)amino]-1H-1,2,4-triazol-3-yl}methanol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Meladrazine

Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Benproperine

Experimental
Matched Iupac: … 1-[1-(2-benzylphenoxy)propan-2-yl]piperidine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Oxypertine

Experimental
Matched Iupac: … 5,6-dimethoxy-2-methyl-3-[2-(4-phenylpiperazin-1-yl)ethyl]-1H-indole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Sitravatinib

Sitravatinib is under investigation in clinical trial NCT03680521 (Neoadjuvant Sitravatinib in Combination With Nivolumab in Patients With Clear Cell Renal Cell Carcinoma).
Investigational
Matched Iupac: … N'1-(3-fluoro-4-{[2-(5-{[(2-methoxyethyl)amino]methyl}pyridin-2-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl ... )-N1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Dorzagliatin

Dorzagliatin is under investigation in clinical trial NCT03173391 (Long-term Efficacy and Safety of HMS5552 in T2DM).
Investigational
Matched Iupac: … (2S)-2-[4-(2-chlorophenoxy)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl]-N-{1-[(2R)-2,3-dihydroxypropyl]-1H-pyrazol ... -3-yl}-4-methylpentanamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Nanatinostat

Nanatinostat is under investigation in clinical trial NCT00697879 (Safety Study of the Histone Deacetylase Inhibitor, CHR-3996, in Patients With Advanced Solid Tumours).
Investigational
Matched Iupac: … ,5S,6R)-6-{[(6-fluoroquinolin-2-yl)methyl]amino}-3-azabicyclo[3.1.0]hexan-3-yl]-N-hydroxypyrimidine-5- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

AZD-7648

Investigational
Matched Iupac: … 7-methyl-2-({7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl}amino)-9-(oxan-4-yl)-8,9-dihydro-7H-purin-8- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Vitexin

Investigational
Matched Iupac: … -4-one ... 5,7-dihydroxy-2-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-4H-chromen …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Tasosartan

Tasosartan is a long-acting angiotensin II (AngII) receptor blocker. Its long duration of action has been attributed to its active metabolite enoltasosartan. It is used to treat patients with essential hypertension.
Experimental
Matched Iupac: … 2,4-dimethyl-8-{[2'-(2H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-5H,6H,7H,8H-pyrido[2,3-d] …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Pipamperone

Pipamperone is a typical antipsychotic of the butyrophenone family used in the treatment of schizophrenia. It was developed by Janssen Pharmaceutica in 1961 and started its first round of clinical trials in 1963 [L1514, L1518]. In an effort to improve haloperidol's pharmacological effects, Janssen discovered that pipamperone, an agent whose...
Investigational
Matched Iupac: … 1'-[4-(4-fluorophenyl)-4-oxobutyl]-[1,4'-bipiperidine]-4'-carboxamide …

Icaridin

Icaridin, also known as Picaridin or hydroxy-ethyl isobutyl piperidine carboxylate, is a cyclic amine and a member of the piperidine chemical family. Piperidines are structural components of piperine, which is a plant extract from the genus _Piper _, or pepper. Icaridin has been commonly used as a topically-applied insect repellent...
Experimental
Matched Iupac: … butan-2-yl 2-(2-hydroxyethyl)piperidine-1-carboxylate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Interferon Kappa

Interferon kappa is a subclass of type I interferon mediating host defence which consists of 207 amino acids and has 30% homology with others of the same class as it consists of a series of cysteine and a 27-amino acid signal peptide conserved in type I interferons. This gene encoding...
Investigational

Sulforaphane

Sulforaphane is under investigation for the treatment of Autism Spectrum Disorder. It is a naturally occurring isothiocyanate found in high concentration in a variety of broccoli.
Investigational
Matched Synonyms: … 4-methylsulfinylbutyl isothiocyanate …
Matched Iupac: … 1-isothiocyanato-4-[(R)-methanesulfinyl]butane …

Acetyl simvastatin

Experimental
Matched Synonyms: … 4'-acetylsimvastatin …
Matched Iupac: … -1-yl 2,2-dimethylbutanoate ... (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-(acetyloxy)-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen …

Olokizumab

Interleukin-6 (IL-6) is an important cytokine with roles in immune cell proliferation/differentiation, energy and bone metabolism, and the acute phase response of the innate immune system. IL-6 pathway dysregulation is associated with chronic inflammation and lymphoproliferation, including in autoimmune conditions such as rheumatoid arthritis, Castleman disease, and cytokine release syndrome....
Investigational

(2S)-2-{3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]-4-methoxybenzyl}butanoic acid

Experimental
Matched Name: … (2S)-2-{3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]-4-methoxybenzyl}butanoic acid …
Matched Iupac: … (2S)-2-{[3-({[2-fluoro-4-(trifluoromethyl)phenyl]formamido}methyl)-4-methoxyphenyl]methyl}butanoic acid …

Viagenpumatucel-L

Viagenpumatucel-L is under investigation in clinical trial NCT02117024 (A Phase 2 Study of Viagenpumatucel-l (HS-110) in Patients With Non-small Cell Lung Cancer).
Investigational

NFS-02

NFS-02 is a recombinant adeno-associated virus serotype 2 containing human mitochondrial ND1 codon optimized gene (rAAV2-ND1).
Investigational

Timbetasin

Timbetasin is under investigation in clinical trial NCT05555589 (Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2).
Investigational
Matched Synonyms: … 3,11,25,31,38-pentakis(de-n6-acetyl)-1,22,30,33-tetrakis(de-o3-phosphono)thymosin .beta.4(human) ... Thymosin .beta.(4), 3,11,25,31,38-pentakis(de-n6-acetyl)-1,22,30,33-tetrakis(de-o3-phosphono)- …

Chlorphentermine

A sympathomimetic agent that was formerly used as an anorectic. It has properties similar to those of dextroamphetamine. It has been implicated in lipid storage disorders and pulmonary hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1223)
Illicit
Withdrawn
Matched Synonyms: … 4-Chloro-a,a-dimethylphenethylamine ... 4-Chloro-a,a-dimethylbenzeneethanamine …
Matched Iupac: … 1-(4-chlorophenyl)-2-methylpropan-2-amine …
Matched Salts cas: … 151-06-4 …
Displaying drugs 10001 - 10025 of 12080 in total