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Displaying drugs 10051 - 10075 of 11959 in total
Vistusertib
Vistusertib is under investigation for the treatment of Advanced Gastric Adenocarcinoma.
Investigational
Matched Iupac: … 3-{2,4-bis[(3S)-3-methylmorpholin-4-yl]pyrido[2,3-d]pyrimidin-7-yl}-N-methylbenzamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Sorivudine
Sorivudine has been used in trials studying the treatment of Chickenpox and HIV Infections.
Investigational
Matched Iupac: … 5-[(E)-2-bromoethenyl]-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Atevirdine
Atevirdine has been used in trials studying the treatment of HIV Infections.
Investigational
Matched Iupac: … N-ethyl-2-[4-(5-methoxy-1H-indole-2-carbonyl)piperazin-1-yl]pyridin-3-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Verucerfont
Verucerfont has been used in trials studying the treatment of Congenital Adrenal Hyperplasia.
Investigational
Matched Iupac: … 3-(4-methoxy-2-methylphenyl)-2,5-dimethyl-N-[(1S)-1-(3-methyl-1,2,4-oxadiazol-5-yl)propyl]pyrazolo[1,5 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ondelopran
Ondelopran has been used in trials studying the treatment of Alcohol Dependence.
Investigational
Matched Iupac: … 6-[2-fluoro-4-({[2-(oxan-4-yl)ethyl]amino}methyl)phenoxy]pyridine-3-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Fazadinium bromide
Experimental
Matched Iupac: … 3-methyl-1-[(E)-2-{3-methyl-2-phenyl-1H-4lambda5-imidazo[1,2-a]pyridin-4-ylium-1-yl}diazen-1-yl]-2-phenyl ... -1H-4lambda5-imidazo[1,2-a]pyridin-4-ylium dibromide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
BMS-986141
BMS-986141 is under investigation in clinical trial NCT02985632 (A Study to Evaluate the Pharmacokinetics of BMS-986141 in Participants With Hepatic Impairment Compared to Healthy Participants).
Investigational
Matched Iupac: … 4-(4-{[(6-methoxy-2-{2-methoxyimidazo[2,1-b][1,3,4]thiadiazol-6-yl}-1-benzofuran-4-yl)oxy]methyl}-1,3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ziresovir
Ziresovir is under investigation in clinical trial NCT03699202 (Anti-RSV Study in Chinese Patients (ASCENT)).
Investigational
Matched Iupac: … 4-(4-{[(3-aminooxetan-3-yl)methyl]amino}-6-methylquinazolin-2-yl)-2,3,4,5-tetrahydro-1lambda6,4-benzothiazepine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Tetroxoprim
Experimental
Matched Iupac: … 5-{[3,5-dimethoxy-4-(2-methoxyethoxy)phenyl]methyl}pyrimidine-2,4-diamine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Inodiftagene vixteplasmid
Inodiftagene vixteplasmid is a plasmid DNA vector encoding the diphtheria toxin A (dT-a) gene under transcriptional regulation of the promoter region of the human H19 gene (an imprinted maternally expressed non-protein coding gene).
Investigational
Doramapimod
Doramapimod is a P38 MAP kinase inhibitor.
Investigational
Matched Iupac: … 3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-1-{4-[2-(morpholin-4-yl)ethoxy]naphthalen-1-yl}urea …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Cetilistat
Cetilistat is a novel inhibitor of pancreatic lipase being developed by Alizyme for the treatment of obesity and associated co-morbidities, including type 2 diabetes.
Investigational
Matched Iupac: … 2-(hexadecyloxy)-6-methyl-4H-3,1-benzoxazin-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Danusertib
Danusertib has been used in trials studying the treatment of Leukemia.
Investigational
Matched Iupac: … N-{5-[(2R)-2-methoxy-2-phenylacetyl]-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-3-yl}-4-(4-methylpiperazin-1-yl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Fiacitabine
Fiacitabine has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections.
Investigational
Matched Iupac: … 4-amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2-dihydropyrimidin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Pridinol
Experimental
Matched Iupac: … 1,1-diphenyl-3-(piperidin-1-yl)propan-1-ol …
Matched Salts cas: … 6856-31-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Salts cas: … 6856-31-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Bemegride
Bemegride is a CNS stimulant that is used to induce convulsions in experimental animals. It has also been used as a respiratory stimulant and in the treatment of barbiturate overdose.
Experimental
Matched Iupac: … 4-ethyl-4-methylpiperidine-2,6-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Firsocostat
Firsocostat is under investigation in clinical trial NCT02781584 (Safety, Tolerability, and Efficacy of Selonsertib, Firsocostat, and Cilofexor in Adults With Nonalcoholic Steatohepatitis (NASH)).
Investigational
Matched Iupac: … 2-{1-[(2R)-2-(2-methoxyphenyl)-2-(oxan-4-yloxy)ethyl]-5-methyl-6-(1,3-oxazol-2-yl)-2,4-dioxo-1H,2H,3H …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Recombinant Bacterial ACE2 Receptors-like Enzyme
B38-CAP is structured as a carboxypeptidase and derived from Paenibacillus sp. The molecule, an Angiotensin Converting Enzyme 2 (ACE2)-like enzyme, shares structural similarities to the mammalian ACE2. B38-CAP is an ACE2-like enzyme which decreases angiotensin II levels. It is being investigated for treating hypertension, myocardial fibrosis, and cardiac dysfunction.
Investigational
UDP-alpha-D-glucuronic acid
A nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides. In animals, UDP glucuronic acid is used for formation of many glucosiduronides with various aglycones. [PubChem]
Experimental
Matched Synonyms: … Uridine-5'-diphosphate-glucuronic acid …
Matched Iupac: … (2S,3S,4S,5R,6R)-6-({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … (2S,3S,4S,5R,6R)-6-({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ticalopride
Investigational
Matched Iupac: … 4-amino-5-chloro-2-methoxy-N-[(3S,4R)-3-methoxypiperidin-4-yl]benzamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Eltoprazine
Eltoprazine has been used in trials studying the treatment of Schizophrenia and Cognitive Impairment.
Investigational
Matched Iupac: … 1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Furazidin
Experimental
Matched Iupac: … 1-[(E)-[(2E)-3-(5-nitrofuran-2-yl)prop-2-en-1-ylidene]amino]imidazolidine-2,4-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 10051 - 10075 of 11959 in total