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Displaying drugs 10101 - 10125 of 11673 in total

Rhenium Re-186 sulfide

Experimental

Fluoroacetic acid F-18

Fluoroacetic acid F-18 is under investigation in clinical trial NCT01320787 (18-F-Fluoroacetate as PET Imaging Agent).
Investigational
Matched Iupac: … 2-(¹⁸F)fluoroacetic acid …

Prolactin G129R

Investigational

Threonine-Aspartic Ester

Experimental
Matched Iupac: … (2S,3R)-2-amino-3-[(1R,3S)-3-amino-3-carboxy-1-hydroxypropoxy]butanoic acid …

Edivoxetine

Edivoxetine is a drug which acts as a selective norepinephrine reuptake inhibitor and is currently under development by Eli Lilly for attention-deficit hyperactivity disorder (ADHD) and as an antidepressant treatment. Edivoxetine failed to be approved for major depressive disorder after phase III clinical trials in 2012.
Investigational
Matched Iupac: … (1R)-2-(5-fluoro-2-methoxyphenyl)-1-[(2S)-morpholin-2-yl]-1-(oxan-4-yl)ethan-1-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Matrix-M

Matrix-M is a saponin-based adjuvant made of nanometer particles, cholesterol, and phospholipid that is developed by Novavax. This compound is administered alongside vaccines to enhance biological functions: creating robust and long-lasting immune responses that may allow for dose-sparing of vaccines.
Investigational

Edodekin alfa

Edodekin alfa is under investigation in clinical trial NCT01468896 (Cetuximab and Recombinant Interleukin-12 in Treating Patients With Squamous Cell Carcinoma of the Head and Neck That Is Recurrent, Metastatic, or Cannot Be Removed by Surgery).
Investigational

Dapaconazole

Dapaconazole has been used in trials studying the treatment of Tinea Pedis.
Investigational
Matched Iupac: … 1-[2-(2,4-dichlorophenyl)-2-{[4-(trifluoromethyl)phenyl]methoxy}ethyl]-1H-imidazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Letrazuril

Letrazuril has been used in trials studying the treatment of HIV Infections and Cryptosporidiosis.
Investigational
Matched Iupac: … 2-[2,6-dichloro-4-(3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazin-2-yl)phenyl]-2-(4-fluorophenyl)acetonitrile …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Phenoperidine

Experimental
Matched Iupac: … ethyl 1-(3-hydroxy-3-phenylpropyl)-4-phenylpiperidine-4-carboxylate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Neflamapimod

Neflamapimod has been used in trials studying the treatment of Alzheimer's Disease and Mild Cognitive Impairment.
Investigational
Matched Iupac: … 5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)sulfanyl]-6H-pyrimido[1,6-b]pyridazin-6-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Sebacic acid

Experimental

Cycloleucine

Cycloleucine is non-metabolisable amino acid formed by cyclization of leucine. It is also a specific and reversible inhibitor of nucleic acid methylation and widely used in biochemical experiments.
Experimental
Matched Synonyms: … 1-amino-1-cyclopentanecarboxylic acid ... 1-aminocyclopentane-1-carboxylic acid ... 1-aminocyclopentanecarboxylic acid …
Matched Iupac: … 1-aminocyclopentane-1-carboxylic acid …

Forodesine

Forodesine is a highly potent, orally active, rationally designed PNP inhibitor that has shown activity in preclinical studies with malignant cells and clinical utility against T-cell acute lymphoblastic leukemia and cutaneous T-cell lymphoma. Additional preliminary findings support its use for the management of some B-cell malignancies.
Investigational
Matched Synonyms: … 1,4-Dideoxy-4-aza-1-(S)-(9-deazahypoxanthin-9-yl)-D-ribitol …
Matched Iupac: … 7-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl]-3H,4H,5H-pyrrolo[3,2-d]pyrimidin-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

Colforsin

Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland.
Experimental
Investigational
Matched Iupac: … (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-dodecahydro ... -1H-naphtho[2,1-b]pyran-5-yl acetate …

Fosfructose

Experimental
Matched Iupac: … {[(3S,4R,5R)-3,4,5-trihydroxy-2-oxo-6-(phosphonooxy)hexyl]oxy}phosphonic acid …
Matched Salts cas: … 81028-91-3 …

Dipicolinic acid

Experimental
Matched Salts cas: … 4220-17-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Prizloncabtagene autoleucel

C-CAR039 is an autologous Chimeric Antigen Receptors (CAR) T-cell therapy expressing CD19/CD20 bi-specific CAR.
Investigational

Recombinant human palmitoyl-protein thioesterase-1

Investigational
Matched Synonyms: … Recombinant human palmitoyl-protein thioeserase-1 ... RECOMBINANT HUMAN PALMITOYL-PROTEIN THIOESERASE-1 (RHPPT1) …
Matched Name: … Recombinant human palmitoyl-protein thioesterase-1 …

UB-612

The UB-612 COVID-19 vaccine was developed by United Biomedical Inc Asia in Taipei as the first COVID-19 “multi-tope” protein-peptide vaccine made up of eight rationally designed components . The vaccine incorporates a strong S1-RBD component linked to a single chain fragment region (sFC) of a human IgG1, which facilitates cell...
Investigational
Matched Description: … rats, toxicity studies have so far shown favourable safety for this vaccine[L30653, L30658], Phase 1 …

Chymostatin

Experimental
Matched Iupac: … (2S)-2-({[(S)-(2-imino-1,3-diazinan-4-yl)({[(1S)-3-methyl-1-{[(2S)-1-oxo-3-phenylpropan-2-yl]carbamoyl ... }butyl]carbamoyl})methyl]carbamoyl}amino)-3-phenylpropanoic acid …

(6E,11E)-HEPTADECA-6,11-DIENE-9,9-DIYLBIS(PHOSPHONIC ACID)

Experimental

(2,2-DIPHOSPHONOETHYL)(DODECYL)DIMETHYLPHOSPHONIUM

Experimental
Matched Iupac: … [2-(dodecyldimethylphosphaniumyl)-1-phosphonoethyl]phosphonic acid …

Eucalyptol

Eucalyptol is naturally produced cyclic ether and monoterpenoid. Eucalyptol is an ingredient in many brands of mouthwash and cough suppressant. It controls airway mucus hypersecretion and asthma via anti-inflammatory cytokine inhibition. Eucalyptol is an effective treatment for nonpurulent rhinosinusitis. Eucalyptol reduces inflammation and pain when applied topically. It kills leukaemia...
Experimental
Nutraceutical
Matched Iupac: … (1s,4s)-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane …

Denenicokin

Denenicokin is under investigation in clinical trial NCT01152788 (Phase II Study of Interleukin-21 (rIL-21) vs Dacarbazine (DTIC) in Patients With Metastatic or Recurrent Melanoma).
Investigational
Displaying drugs 10101 - 10125 of 11673 in total