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Displaying drugs 1001 - 1025 of 1410 in total
Investigational
Matched Synonyms: … -l-fuc-(1->2))-d-gal …
Azacitidine is a pyrimidine nucleoside analogue with anti-neoplastic activity. It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.[A1406,A1413,A1415] Two main mechanisms of action have been proposed for azacitidine. One of them is the induction of cytotoxicity. As an analogue of cytidine, it...
Approved
Investigational
Matched Description: … As an analogue of cytidine, it is able to incorporate into RNA and DNA, disrupting RNA metabolism and ... inhibiting protein and DNA synthesis. ... [A1407] Due to its anti-neoplastic activity and its ability to inhibit methylation in replicating DNA …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … XPREZA 100 INJECTION 100 MG/VIAL ... ARGAXIT®100 MG ... NEXTIDINA® 100 MG …
A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders.
Approved
Matched Description: … A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary ... Danazol has been used in the treatment of endometriosis and some benign breast disorders. …
Matched Categories: … Antigonadotropins and Similar Agents ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … DANASIN 100 MG KAPSUL, 100 ADET ... วาบอน-100 ... อนาจิล (100 มก.) …
Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis.[A3811, A260880, L40968] Abiraterone was first approved by the FDA and EMA on April, July, and September 2011, respectively. It is used to treat metastatic...
Approved
Matched Description: … ] and September 2011,[A260880] respectively. ... Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17 ... ), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... niraparib and abiraterone ... abiraterone and prednisolone ... Hormone Antagonists and Related Agents ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … TEROPROS FILM COATED TABLET 1000MG ... Abirateron Sandoz 1000 mg – Filmtabletten ... Abirateron 1A Pharma 1000 mg – Filmtabletten …
Investigational
Matched Synonyms: … 6-oxo-5,5a,6,8,8a,9-hexahydro-2h-furo(3',4':6,7)naphtho(2,3-d)(1,3)dioxol-5-yl)-2,6-dimethoxyphenyl carbonate
Matched Iupac: … .0^{11,15}]hexadeca-1(9),2,7-trien-10-yl]-2,6-dimethoxyphenyl (2,2-dimethyl-1,3-dioxolan-4-yl)methyl carbonate
Zonisamide is a sulfonamide anticonvulsant used as an adjunctive therapy in adults with partial-onset seizures.[L42530,L42535] Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels, leading to a reduction of T-type calcium channel currents or by binding allosterically to GABA receptors. This latter action may inhibit the uptake of...
Approved
Investigational
Matched Description: … The US and Europe approved it in 2000 and 2005, respectively.[A1379,A1383] …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Products: … ZALIPIN 100 MG KAPSÜL ,100 KAPSÜL ... EPİZONYA 100 MG KAPSÜL, 100 ADET ... EXCEGRAN 100 MG KAPSUL, 100 ADET …
Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins. It is further classified as a second-generation progestin, along with levonorgestrel and its derivatives, and is the active form of several other progestins including norethynodrel and lynestrenol. Norethisterone mimics the actions of endogenous...
Approved
Matched Description: … derivatives, and is the active form of several other progestins including [norethynodrel] and [lynestrenol ... [A10367] It is further classified as a second-generation progestin, along with [levonorgestrel] and its ... endometriosis, and was not marketed for use as an oral contraceptive until 1962. …
Matched Mixtures name: … Norethindrone and Ethinyl Estradiol and Ferrous Fumarate ... Norethindrone and Ethinyl Estradiol and Ferrous Fumarate ... Norethindrone and Ethinyl Estradiol, and Ferrous Fumarate …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Combination Contraceptives (with Estrogen and derivatives) ... Sex Hormones and Insulins ... norethisterone and estrogen ... norethisterone and estrogen …
Matched Products: … PRIMOLUT-N 5 MG TABLET, 1000 ADET …
A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome. Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994,...
Approved
Matched Description: … for the suppression of vocal and motor tics in patients with Tourette syndrome. ... A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol …
Matched Products: … NOROFREN 2 MG TABLET, 1000 ADET …
Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults.[A188309,L10544,L43478] Since 2012, the extended-release formulation has been approved in combination with phentermine for chronic weight management therapy...
Approved
Matched Description: … Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. ... topiramate from other antiepileptic drugs are a monosaccharide chemical structure containing a sulfamate, and
Matched Categories: … Alimentary Tract and Metabolism ... phentermine and topiramate …
Matched Products: … Qudexy XR ... Trokendi XR ... EXPLIGA XR
A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
Approved
Matched Description: … that can be used for the relief of most types of moderate to severe pain, including postoperative pain and ... lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and
Matched Mixtures name: … Meperidine Hcl and Promethazine Hcl ... Meperidine Hydrochloride and Promethazine Hydrochloride …
Matched Categories: … pethidine and antispasmodics …
Matched Products: … Demerol 100 mg/ml ... DEMOTHINE INJECTION 100MG/2ML ... Demerol 10%-liq Im Sc 100mg/ml …
Posaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
Approved
Investigational
Vet approved
Matched Description: … Posaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and
Matched Categories: … Triazole and tetrazole derivatives ... Metabolic Side Effects of Drugs and Substances ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … NOXAFIL TABLET 100MG ... Ossmiq 100 mg - magensaftresistente Tabletten ... Noxafil 100mg Modified Release Tablet …
Experimental
Matched Mixtures name: … HERREX® FOL 1000 TABLETAS RECUBIERTAS ... FERLOS 100 MG/0.35 MG TABLET, 30 ADET ... SANTAFER FORT 100MG/0,35 MG FILM KAPLI TABLET, 30 ADET …
Matched Products: … DUNOXSOL 100 ... MALTOFER FILM-COATED TABLETS 100MG ... SANTAFER 100MG/2ML AMPUL, 5 ADET …
Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies [A19667, A19668, A19670]. Aceclofenac potently inhibits the...
Approved
Investigational
Matched Description: … Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and ... analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. ... synthesis of prostaglandins, which are inflammatory mediators that cause pain, swelling, inflammation, and
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … AINEDIX AC® 100 MG ... AIRTAL FILM COATED TABLETS 100mg ... Airtal 100mg Film-coated Tablet …
Racecadotril has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and Acute Gastroenteritis.
Investigational
Matched Description: … Racecadotril has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Products: … easystop 100 mg Hartkapseln ... Hidrasec 100 mg Hartkapseln ... HIDRASEC CAPSULAS 100 MG …
Pinaverium is a spasmolytic agent used for functional gastrointestinal disorders. It is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel function. It is shown to relieve GI spasm and pain, transit disturbances and other symptoms related to motility disorders and may be considered...
Approved
Matched Description: … It is shown to relieve GI spasm and pain, transit disturbances and other symptoms related to motility ... disorders [A19697] and may be considered as effective first-lline therapy for patients with irritable ... Pinaverium bromide is the common ingredient in formulations, mostly as oral tablets. …
Matched Mixtures name: … BROMUX D® 100/300 MG CÁPSULA. …
Matched Salts name: … Pinaverium bromide
Matched Categories: … Alimentary Tract and Metabolism ... Calcium-Regulating Hormones and Agents …
Matched Products: … PYNAZER® 100 MG ... BROMUX 100MG TABLETAS. ... DICETEL® TABLETAS 100 MG …
Sapropterin (tetrahydrobiopterin or BH4) is a cofactor in the synthesis of nitric oxide. It is also essential in the conversion of phenylalanine to tyrosine by the enzyme phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and conversion of tryptophan to 5-hydroxytryptophan via tryptophan hydroxylase.
Approved
Investigational
Matched Description: … phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Various Alimentary Tract and Metabolism Products …
Matched Products: … KUVAN® 100 MG ... KUVAN 100 MG ÇÖZÜNEBİLİR TABLET, 120 ADET ... KUVAN 100 MG ÇÖZÜNEBİLİR TABLET, 240 ADET …
Cefdinir, also known as Omnicef, is a semi-synthetic, broad-spectrum antibiotic belonging to the third generation of the cephalosporin class. It has been proven to be effective for the treatment of common bacterial infections in the ear, sinus, throat, lungs, and skin. Cefdinir was approved by the FDA in 1997 to...
Approved
Matched International brands: … Xi Fu Ni …
Matched Description: … to be effective for the treatment of common bacterial infections in the ear, sinus, throat, lungs, and ... Cefdinir was approved by the FDA in 1997 to treat a variety of mild to moderate infections and was initially …
Matched Mixtures name: … TAMCEF PLUS 125 MG + 62,5 MG / 5 ML ORAL SUSPANSIYON HAZIRLAMAK ICIN KURU TOZ, 100 ML …
Matched Products: … แซมเนียร์ 100 มก. ชนิดแคปซูล ... CLASEM 125 MG/5ML ORAL SUSPANSIYON ICIN TOZ, 100 ML ... CLASEM 250 MG/5ML ORAL SUSPANSIYON ICIN TOZ, 100 ML …
Tiapride is a selective D2 and D3 dopamine receptor blocker in the brain.
Investigational
Matched Description: … Tiapride is a selective D2 and D3 dopamine receptor blocker in the brain. …
Matched Categories: … Benzamides and benzamide derivatives …
Matched Products: … TIAPRID HEXAL 100MG ... TIAPRID STADA 100MG ... TIAPRID 100 1A PHARMA …
Dasatinib is an orally available multikinase inhibitor indicated for the treatment of Philadelphia chromosome (Ph)-positive leukemias.[A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region (BCR) gene transcribe the chimeric protein...
Approved
Investigational
Matched Description: … pathogenesis of CML and 15-30% of ALL cases. ... A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and ... acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region (BCR …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … LITEDA 100 MG ... REMBRE 100 MG ... Pharma 100 mg-Filmtabletten …
Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's...
Approved
Investigational
Matched Description: … blocks the effects of glutamate, a neurotransmitter in the brain that leads to neuronal excitability and ... doubling every 20 years, the prevalence of Alzheimer's Disease is predicted to reach 66 million by 2030 and
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Categories: … donepezil and memantine ... donepezil, memantine and Ginkgo folium …
Matched Products: … Namenda XR ... MEXIA XR 14 MG UZATILMIŞ SALINIMLI MIKROPELLET KAPSÜL ,28 UZATILMIŞ SALINIMLI MIKROPELLET KAPSÜL ... MEXIA XR 28 MG UZATILMIŞ SALINIMLI MIKROPELLET KAPSÜL ,28 UZATILMIŞ SALINIMLI MIKROPELLET KAPSÜL …
Miglustat, commonly marketed under the trade name Zavesca, is a drug used to treat Gaucher disease. It inhibits the enzyme glucosylceramide synthase, an essential enzyme for the synthesis of most glycosphingolipids. It is only used for patients who cannot be treated with enzyme replacement therapy with imiglucerase. Miglustat is now...
Approved
Matched Description: … patients in the European Union, Brazil, and South Korea. ... Miglustat is now the first and only approved therapy for patients with Niemann-Pick disease type C (NP-C ... It has recently been approved for treatment of progressive neurological symptoms in adult and pediatric …
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …
Matched Products: … ZAVESCA® 100 MG ... Miglustat G.L. 100 mg-Hartkapseln ... ZAVESCA 100 MG KAPSUL, 84 ADET …
IMOGAM Rabies Pasteurized is indicated for post-exposure prophylaxis in persons suspected of exposure to rabies, who have not previously received a complete immunization regimen with a cell culture produced rabies vaccine. Persons previously vaccinated with other types of rabies vaccines in whom adequate antibody levels have not been demonstrated should...
Approved
Matched Description: … adequate antibody levels have not been demonstrated should receive full post-exposure prophylaxis with RIG and ... Recommendations for passive and/or active immunization after exposure to an animal suspected of having ... Advisory Committee on Immunization (NACI), the Advisory Committee on Immunization Practices (ACIP), and
Matched Products: … EQUIRAB 1000 IU/5ML IM/SC ÇÖZELTI IÇEREN FLAKON, 1 ADET …
Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of antidepressants. It is used in adults and has been shown to be comparable in efficacy to other drugs such as tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine receptor inhibitor (SNRIs) in the...
Approved
Investigational
Matched Description: … Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors ... [A181180] It is used in adults and has been shown to be comparable in efficacy to other drugs such as ... tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine …
Matched Categories: … Serotonin antagonist and reuptake inhibitors (SARIs) …
Matched Products: … DESYREL XL 150 MG UZATILMIŞ SALIMLI FİLM TABLET , 10 TABLET ... DESYREL XL 150 MG UZATILMIŞ SALIMLI FİLM TABLET , 14 TABLET ... DESYREL XL 150 MG UZATILMIŞ SALIMLI FİLM TABLET , 20 TABLET …
Udenafil is a new phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED). It has been approved in South Korea and will be marketed under the brand name Zydena. It is not yet approved for use in the U.S., E.U., or Canada.
Approved
Investigational
Matched Description: … It has been approved in South Korea and will be marketed under the brand name Zydena. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … ZYDENA 100 MG ... ZYDENA 100 TABLET ... ZYDENA 100 MG FILM TABLET, 2 ADET …
Bendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL). Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules. Through this function as an alkylating agent, bendamustine...
Approved
Investigational
Matched Description: … a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and ... Through this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks ... It is active against both active and quiescent cells, although the exact mechanism of action is unknown …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … BENTERO 100 ... RAMIZA 100 ... XEBINA®100MG
Displaying drugs 1001 - 1025 of 1410 in total