Displaying drugs 10376 - 10400 of 12422 in total
Cyclomethicone 5
Cyclomethicone 5 is member of cyclomethicone, which are a group of liquid methyl siloxanes that have low viscosity and high volatility. Cyclomethicones are cyclic in structure with a monomer backbone of one silicon and two oxygen atoms bonded together. Cyclomethicone 5 is used in cosmetic and personal products as a...
Experimental
Matched Description: … Cyclomethicone 5 is member of cyclomethicone, which are a group of liquid methyl siloxanes that have ... Cyclomethicones are cyclic in structure with a monomer backbone of one silicon and two oxygen atoms bonded …
CNS-5161
CNS 5161 is a blocker of the NMDA ion channel and has completed Phase IIa proof of concept clinical trials as a novel compound for the treatment of neuropathic pain.
Investigational
Matched Description: … CNS 5161 is a blocker of the NMDA ion channel and has completed Phase IIa proof of concept clinical trials ... as a novel compound for the treatment of neuropathic pain. …
Oportuzumab monatox
VB4-845 is studied in the treatment of certain types of head and neck cancer. VB4-845 is made by linking a monoclonal antibody fragment to a toxic protein that may kill cancer cells. VB4-845 is a fusion protein containing humanized scFv specific for the epithelial cell adhesion molecule, Ep-CAM, a tumor...
Investigational
Matched Description: … VB4-845 is studied in the treatment of certain types of head and neck cancer. ... epithelial origin and a truncated portion of Pseudomonas exotoxin A. ... cell adhesion molecule, Ep-CAM, a tumor cell-associated target highly expressed on carcinoma cells of …
Human Menstrual Blood-derived Stem Cells
Stem cells are self-renewing and proliferate without differentiation, with the two major groups being embryonic stem cells (ESCs) and adult stem cells (ASC). Differentiation occurs under different conditions into different cell types. ESCs are from the inner cell mass of blastocysts while ASCs are deposited into adult tissues with restricted...
Investigational
Matched Description: … differentiation potency but also a lack of tumorigenicity. ... ethical issues that may come from obtaining stem cells of the embryonic kind. ... These cells possess a high rate of proliferation and multi-lineage differentiation potency. …
Besifovir dipivoxil
Besifovir dipivoxil is a small-molecule orally available inhibitor of the HBV polymerase. The HBV polymerase is the enzyme that catalyzes the production of new RNA from the existing strand of RNA. Besifovir dipivoxil is believed to inhibit viral proliferation by interrupting the replicating machinery of the virus.
Investigational
Matched Description: … The HBV polymerase is the enzyme that catalyzes the production of new RNA from the existing strand of ... Besifovir dipivoxil is a small-molecule orally available inhibitor of the HBV polymerase. ... Besifovir dipivoxil is believed to inhibit viral proliferation by interrupting the replicating machinery of …
Nebicapone
Nebicapone is under investigation in clinical trial NCT03097211 (Effect of BIA 6-512 at Steady-state on the Levodopa Pharmacokinetics With a Single-dose of Levodopa/Benserazide 200/50 mg or With a Single-dose of Levodopa/Benserazide 200/50 mg Plus a Single-dose of Nebicapone 150 mg).
Investigational
Matched Description: … of Levodopa/Benserazide 200/50 mg Plus a Single-dose of Nebicapone 150 mg). ... Nebicapone is under investigation in clinical trial NCT03097211 (Effect of BIA 6-512 at Steady-state ... on the Levodopa Pharmacokinetics With a Single-dose of Levodopa/Benserazide 200/50 mg or With a Single-dose …
BTA798
BTA798 is an antiviral for the treatment of HRV, the common cold virus, known to cause significant clinical complications in sufferers of Asthma and Chronic Obstructive Pulmonary Disease.
Investigational
Matched Description: … complications in sufferers of Asthma and Chronic Obstructive Pulmonary Disease. ... BTA798 is an antiviral for the treatment of HRV, the common cold virus, known to cause significant clinical …
WL-1002
WL-1002 is developed by Winston Laboratories which is a topical cream formulation of 075% zucapaicin (also known as civamide), for the treatment of pain due to osteoarthritis.
Investigational
Matched Description: … (also known as civamide), for the treatment of pain due to osteoarthritis. ... WL-1002 is developed by Winston Laboratories which is a topical cream formulation of 075% zucapaicin …
Contulakin-G
Contulakin-G is a broad spectrum non-opioid analgesic. It is the synthetic form of a natural peptide extracted from the venom of the Conus Geographus sea snail.
Investigational
Matched Description: … It is the synthetic form of a natural peptide extracted from the venom of the Conus Geographus sea snail …
PF-232798
PF-232798 is under investigation in clinical trial NCT01140425 (Study To Evaluate The Effect Of A Multiple Oral Dose Of PF-00232798 On QT Intervals In Healthy Subjects).
Investigational
Matched Description: … Oral Dose Of PF-00232798 On QT Intervals In Healthy Subjects). ... PF-232798 is under investigation in clinical trial NCT01140425 (Study To Evaluate The Effect Of A Multiple …
Adagloxad simolenin
Adagloxad simolenin is under investigation in clinical trial NCT03562637 (Study of Adagloxad Simolenin (OBI-822)/OBI-821 in the Adjuvant Treatment of Patients With Globo H Positive TNBC).
Investigational
Matched Description: … (OBI-822)/OBI-821 in the Adjuvant Treatment of Patients With Globo H Positive TNBC). ... Adagloxad simolenin is under investigation in clinical trial NCT03562637 (Study of Adagloxad Simolenin …
Dapansutrile
Dapansutrile is under investigation in clinical trial NCT01768975 (Phase 2 Efficacy Trial of OLT1177 Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee).
Investigational
Matched Description: … Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee). ... Dapansutrile is under investigation in clinical trial NCT01768975 (Phase 2 Efficacy Trial of OLT1177 …
Nadecnemab
Nadecnemab is under investigation in clinical trial NCT03956550 (A Study to Examine the Efficacy and Safety of REGN5069 in Patients With Pain Due to Osteoarthritis of the Knee).
Investigational
Matched Description: … REGN5069 in Patients With Pain Due to Osteoarthritis of the Knee). ... Nadecnemab is under investigation in clinical trial NCT03956550 (A Study to Examine the Efficacy and Safety of …
BEA-17
BEA-17 is a small molecule targeted degrader of the epigenetic enzyme LSD1 and its co-factor CoREST. It is under investigation for the treatment of glioblastoma.
Investigational
Matched Description: … [L48330] It is under investigation for the treatment of glioblastoma. ... BEA-17 is a small molecule targeted degrader of the epigenetic enzyme LSD1 and its co-factor CoREST. …
Sulforaphane
Sulforaphane is under investigation for the treatment of Autism Spectrum Disorder. It is a naturally occurring isothiocyanate found in high concentration in a variety of broccoli.
Investigational
Matched Description: … Sulforaphane is under investigation for the treatment of Autism Spectrum Disorder. ... It is a naturally occurring isothiocyanate found in high concentration in a variety of broccoli. …
GS-9191
GS-9191 is under investigation in clinical trial NCT00499967 (Safety and Effectiveness Study of an Experimental Topical Ointment (GS-9191) for the Treatment of Genital Warts).
Investigational
Matched Description: … Topical Ointment (GS-9191) for the Treatment of Genital Warts). ... GS-9191 is under investigation in clinical trial NCT00499967 (Safety and Effectiveness Study of an Experimental …
Ecraprost
Ecraprost is under investigation in clinical trial NCT00059657 (Efficacy/safety of Ecraprost in Lipid Emulsion for Treatment of Critical Leg Ischemia Due to Peripheral Arterial Disease).
Investigational
Matched Description: … Emulsion for Treatment of Critical Leg Ischemia Due to Peripheral Arterial Disease). ... Ecraprost is under investigation in clinical trial NCT00059657 (Efficacy/safety of Ecraprost in Lipid …
XMT-2056
XMT-2056 is a HER2-targeted antibody-drug conjugate (ADC) consisting of a HER2-targeted antibody conjugated with a stimulator of interferon genes (STING) agonist payload.
Investigational
Matched Description: … with a stimulator of interferon genes (STING) agonist payload. ... XMT-2056 is a HER2-targeted antibody-drug conjugate (ADC) consisting of a HER2-targeted antibody conjugated …
CCX915
CCX915 is developed by ChemoCentryx which targets the chemokine receptor CCR2 and is in phase 1 of clinical trial for the treatment of Multiple Sclerosis and Neurologic Disorders. The CCR2 receptor is thought to be of central importance to inflammatory diseases, such as multiple sclerosis (MS), Type II diabetes and...
Investigational
Matched Description: … trial for the treatment of Multiple Sclerosis and Neurologic Disorders. ... CCX915 is developed by ChemoCentryx which targets the chemokine receptor CCR2 and is in phase 1 of clinical ... The CCR2 receptor is thought to be of central importance to inflammatory diseases, such as multiple sclerosis …
ZEN-012
ZEN-012 is a novel small molecule and the first anti-cancer drug in development involving two mechanisms of action: tubulin and topoisomerase II inhibition. ZEN-012 also expresses additional modes of action such as pro-apoptotic and anti-angiogenic properties. It is developed for the treatment of solid tumors.
Investigational
Matched Description: … It is developed for the treatment of solid tumors. ... 012 is a novel small molecule and the first anti-cancer drug in development involving two mechanisms of ... ZEN-012 also expresses additional modes of action such as pro-apoptotic and anti-angiogenic properties …
COVID-19 Nucleocapsid-GM-CSF Protein Lactated Ringer's Injection
As of July 2020, Medicine Invention Design, Inc. is sponsoring a small, controlled clinical trial for the COVID-19 AP TP Vaccine for ‘proof of concept.’ The vaccine utilizes granulocyte macrophage-colony stimulating factor (GM-CSF), a cytokine known to enhance vaccine efficacy through prolongation of humoral and cell immunity.
Investigational
Matched Description: … the COVID-19 AP TP Vaccine for ‘proof of concept.’ ... As of July 2020, Medicine Invention Design, Inc. is sponsoring a small, controlled clinical trial for ... macrophage-colony stimulating factor (GM-CSF), a cytokine known to enhance vaccine efficacy through prolongation of …
OTL-201
OTL-201 is an investigational hematopoietic stem cell (HSC) gene therapy being developed by Orchard Therapeutics for the treatment of mucopolysaccharidosis type IIIA (MPS-IIIA). It consists of a lentiviral vector to insert a functional copy of the human N-Sulfoglucosamine Sulfohydrolase (SGSH) gene into autologous CD34+ hematopoietic stem cells.
Investigational
Matched Description: … It consists of a lentiviral vector to insert a functional copy of the human N-Sulfoglucosamine Sulfohydrolase ... hematopoietic stem cell (HSC) gene therapy being developed by Orchard Therapeutics for the treatment of …
Cytisine
Cytisine is an alkaloid naturally derived from the Fabaceae family of plants including the genera Laburnum and Cytisus. Recent studies have shown it to be a more effective and significantly more affordable smoking cessation treatment than nicotine replacement therapy. Also known as baptitoxine or sophorine, cytisine has been used as...
Experimental
Matched Description: … similar efficacy to varenicline, but at a fraction of the cost. ... Cytisine is a partial nicotinic acetylcholine agonist with a half-life of 4.8 hours. ... Cytisine is an alkaloid naturally derived from the Fabaceae family of plants including the genera Laburnum …
Cusatuzumab
CD70 is a ligand expressed on the surface of activated lymphocytes and mature dendritic cells that, in its binding to CD27 receptors, plays an important role in cell proliferation and survival. An overexpression of CD70 can result in the proliferation of malignant cells and has been documented in a variety...
Investigational
Matched Description: … An overexpression of CD70 can result in the proliferation of malignant cells and has been documented ... in a variety of solid and hematological malignancies. ... CD70 is a ligand expressed on the surface of activated lymphocytes and mature dendritic cells that, in …
5-Methoxy-N,N-diisopropyltryptamine
5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) is a tryptamine derivative and shares many similarities with schedule I tryptamine hallucinogens such as alpha-ethyltryptamine, N,N-dimethyltryptamine, N,N-diethyltryptamine, bufotenine, psilocybin and psilocin. Since 1999, there has been a growing popularity of 5-MeO-DIPT among drug abusers. This substance is abused for its hallucinogenic effects.
Experimental
Illicit
Matched Description: … Since 1999, there has been a growing popularity of 5-MeO-DIPT among drug abusers. …
Displaying drugs 10376 - 10400 of 12422 in total