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Displaying drugs 10451 - 10475 of 13144 in total
A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS. [PubChem]
Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Tetomilast has been used in trials studying the treatment of Crohn Disease, Colitis, Ulcerative, and Chronic Obstructive Pulmonary Disease.
Investigational
Matched Iupac: … 6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Cardarine (GW-501516) is a peroxisome proliferator-activator receptor-delta agonist for the potential treatment of dyslipidemia. Cardarine has been investigated for the treatment of Obesity, Lipid Disorders, and Cardiovascular Disease.
Investigational
Matched Iupac: … 2-{2-methyl-4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)sulfanyl]phenoxy}acetic …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
CLX-0921 is investigated for use/treatment in diabetes mellitus type 2. CLX-0921 is a solid. CLX-0921 has a spectrum of activity that differs from commercially available thiazolidinediones. This substance targets the protein peroxisome proliferator-activated receptor gamma. It is a pharmacologically active antihyperglycemic agent that acts by increasing peripheral tissue sensitivity to...
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Investigational
Matched Iupac: … (2S)-N-[(1S)-2,2-dimethyl-1-(methylcarbamoyl)propyl]-4-methyl-2-[(2S)-2-sulfanyl-4-(3,4,4-trimethyl-2,5 ... -dioxoimidazolidin-1-yl)butanamido]pentanamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Uprosertib has been used in trials studying the treatment of Cancer, Melanoma, Solid Tumours, Cervical Cancer, and HER2/Neu Negative, among others.
Investigational
Matched Iupac: … N-[(2S)-1-amino-3-(3,4-difluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)furan …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
AZD7762 has been investigated for the treatment of Cancer, Solid Tumors, and Advanced Solid Malignancies.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
MBX-2982 has been used in trials studying the treatment of Diabetes.
Investigational
Matched Iupac: … 5-ethyl-2-[4-(4-{[4-(1H-1,2,3,4-tetrazol-1-yl)phenoxy]methyl}-1,3-thiazol-2-yl)piperidin-1-yl]pyrimidine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Alagebrium has been investigated for the treatment and prevention of Aging, Heart Failure, Physical Activity, Diabetic Nephropathy, and Cardiovascular Disease, among others.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Irdabisant has been used in trials studying Cognitive Impairment.
Investigational
Matched Iupac: … 6-(4-{3-[(2R)-2-methylpyrrolidin-1-yl]propoxy}phenyl)-2,3-dihydropyridazin-3-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
JNJ-39220675 has been used in trials studying the treatment of Allergic Rhinitis.
Investigational
Matched Iupac: … 1-cyclobutyl-4-[6-(4-fluorophenoxy)pyridine-3-carbonyl]-1,4-diazepane …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Penclomedine has been used in trials studying the treatment of Lymphoma and Unspecified Adult Solid Tumor, Protocol Specific.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
PF-06751979 is under investigation in clinical trial NCT03126721 (The Study is to Evaluate the Effect of Multiple Doses PF-06751979 on the Pharmacokinetics of Midazolam in Healthy Adults).
Investigational
Matched Iupac: … -{2-[(4aR,6S,8aR)-2-amino-6-methyl-4H,4aH,5H,6H,8H,8aH-pyrano[3,4-d][1,3]thiazin-8a-yl]-1,3-thiazol-4- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
RO-6870810 is under investigation in clinical trial NCT02308761 (A Study of RO6870810/TEN-010 in Participants With Acute Myeloid Leukemia and Myelodysplastic Syndrome).
Investigational
Matched Iupac: … (6),4,7,10,12-pentaen-9-yl]-N-[3-(4-methylpiperazin-1-yl)propyl]acetamide ... 2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6}]trideca-2 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Abeprazan is under investigation in clinical trial NCT04341454 (Study to Evaluate the Efficacy and Safety of DWP14012 in Patients With Acute or Chronic Gastritis).
Investigational
Matched Iupac: … {[5-(2,4-difluorophenyl)-1-(3-fluorobenzenesulfonyl)-4-methoxy-1H-pyrrol-3-yl]methyl}(methyl)amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Humanized IgG1 Mab that binds to the human interleukin-2 receptor (anti-Tac or anti-CD25). Daclizumab is a composite of human (90%) and murine (10%) antibody sequences. The human sequences were derived from the constant domains of human IgG1 and the variable framework regions of the Eu myeloma antibody. The murine sequences...
Investigational
Withdrawn
Matched Description: … Daclizumab is a composite of human (90%) and murine (10%) antibody sequences. ... Despite being approved for use, Zinbryta (daclizumab)'s complex pre-existing safety profile consisting …
Chlorophetanol is an agent known to have antifungal activities.
Experimental
Matched Synonyms: … 2-(4-Chlorophenoxy)ethanol ... 2-(4-chlorphenoxy)-ethanol …
Matched Iupac: … 2-(4-chlorophenoxy)ethan-1-ol …
Matched Categories: … 2-(4-chlorphenoxy)-ethanol …
Experimental
Matched Name: … CoA-S-acetyl 5-bromotryptamine …
Matched Iupac: … ethyl]carbamoyl}-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-4- …
Experimental
Matched Iupac: … amino]-3-hydroxypropan-1-one ... (2S)-2-amino-1-[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}sulfonyl) …
Experimental
Matched Name: … (C8-S)-Hydantocidin 5'-phosphate …
Experimental
Matched Iupac: … (2S)-2-hydroxypropan-1-aminium …
123I-iodometomidate is under investigation in clinical trial NCT00454103 (Evaluation of 123I-Iodometomidate for Adrenal Scintigraphy).
Investigational
Matched Iupac: … methyl 1-[(1R)-1-(4-iodophenyl)ethyl]-1H-imidazole-5-carboxylate …
Fluoroacetic acid F-18 is under investigation in clinical trial NCT01320787 (18-F-Fluoroacetate as PET Imaging Agent).
Investigational
Displaying drugs 10451 - 10475 of 13144 in total