Displaying drugs 10526 - 10550 of 12589 in total
NCX 1022
NCX is an NO-releasing derivative of hydrocortisone.
Investigational
Matched Description: … NCX is an NO-releasing derivative of hydrocortisone. …
HPV-16 trojan peptide vaccine
HPV-16 trojan peptide vaccine is an investigational cancer immunotherapy consisting of a novel Trojan peptide complex, composed of human papilloma virus 16 (HPV 16) epitopes, to stimulate antigen-specific CD4 and CD8 T cell responses.
Investigational
Matched Description: … HPV-16 trojan peptide vaccine is an investigational cancer immunotherapy consisting of a novel Trojan ... peptide complex, composed of human papilloma virus 16 (HPV 16) epitopes, to stimulate antigen-specific …
Adinazolam
Adinazolam (Deracyn®) is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative, and antidepressant properties. Adinazolam was first developed to enhance the antidepressant effects of alprazolam. It has never been approved by the FDA for clinical use.
Experimental
Matched Description: … Adinazolam was first developed to enhance the antidepressant effects of [alprazolam]. …
Pexelizumab
Pexelizumab is a humanized monoclonal antibody used as an immunosuppressive drug. It is being investigated by Alexion Pharmaceuticals.
Investigational
PH94B
PH94B is being developed by Pherin Pharmaceuticals, Inc. for the treatment of social phobias (generalized anxiety disorder). It is a member of a new family of pharmaceutical compounds called vomeropherins.
Investigational
Matched Description: … It is a member of a new family of pharmaceutical compounds called vomeropherins. ... PH94B is being developed by Pherin Pharmaceuticals, Inc. for the treatment of social phobias (generalized …
BTA9881
BTA9881 is a respiratory syncytial virus (RSV) antiviral drug developed by the Australian company Biota Holdings. It is currently in phase I trials.
Investigational
APD791
APD791 is an oral anti-thrombotic drug candidate being evaluated in a Phase 1 clinical trial by Arena. APD791 is intended to lower the risk of arterial thrombosis by reducing the amplification of platelet aggregation, arterial constriction and intimal hyperplasia mediated by serotonin.
Investigational
Matched Description: … APD791 is intended to lower the risk of arterial thrombosis by reducing the amplification of platelet …
Captodiame
Captodiame, also known as captodiamine, is an antihistamine which is used as a sedative and anxiolytic. It is a derivative of diphenhydramine. Captodiame has been suggested for use in preventing benzodiazepine withdrawal syndrome.
Experimental
Matched Description: … It is a derivative of diphenhydramine. …
PLN-74809
PLN-74809 is a small-molecule that dually inhibits both αvβ6 and αvβ1 to treat both idiopathic pulmonary fibrosis (IPF) and primary sclerosing cholangitis (PSC) . The compound was granted orphan drug designation by the US FDA in August 2018 for treatment of IPF, and Pliant Therapeutics recently raised $100 million in...
Investigational
Matched Description: … The compound was granted orphan drug designation by the US FDA in August 2018 for treatment of IPF, and ... In addition, the compound is also currently in Phase 2a trials (NCT04565249) for the treatment of COVID ... Therapeutics recently raised $100 million in Series C financing to support further clinical development of …
IDM-1
IDM-1 is IDM’s most advanced antibody-based Cell drug for the treatment of cancer. It is comprised of MAK(Monocytes-derived Activated Killer) cells associated with MDX-210, a bispecific anti-HER-2/neu antibody developed by Medarex Inc.
Investigational
Matched Description: … IDM-1 is IDM’s most advanced antibody-based Cell drug for the treatment of cancer. ... It is comprised of MAK(Monocytes-derived Activated Killer) cells associated with MDX-210, a bispecific …
CERE-110
CERE-110 is a gene-therapy product that involves in vivo delivery of nerve growth factor (NGF) genes through an adeno-associated viral vector (AAV) delivery system. This drug is developed by Ceregene and currently under phase I of clinical trial.
Investigational
Matched Description: … This drug is developed by Ceregene and currently under phase I of clinical trial. ... CERE-110 is a gene-therapy product that involves in vivo delivery of nerve growth factor (NGF) genes …
Nitenpyram
Nitenpyram is an insecticide used in agriculture and veterinary medicine to kill external parasites of pets. It is a neonicotinoid, a neurotoxin that blocks neural messages and binds particularly tightly in the central nervous system of insects, causing rapid death.
Experimental
Vet approved
Matched Description: … Nitenpyram is an insecticide used in agriculture and veterinary medicine to kill external parasites of ... neurotoxin that blocks neural messages and binds particularly tightly in the central nervous system of …
Pentaglobin
Pentaglobin, also known as IgM-enriched immunoglobulin, falls under a group of polyclonal immunoglobulin preparations. It is comprised of immunoglobulin G (IgG) (https://www.drugbank.ca/drugs/DB00028) and immunoglobulin A (IgA) while also being enriched by immunoglobulin M (IgM).
Investigational
Matched Description: … Pentaglobin, also known as IgM-enriched immunoglobulin, falls under a group of polyclonal immunoglobulin ... [A220173] It is comprised of [immunoglobulin G (IgG)](https://www.drugbank.ca/drugs/DB00028) and immunoglobulin …
SB 11285
SB 11285 is a second-generation Stimulator of Interferon Genes (STING) agonist. SB 11285 is under investigation in clinical trial NCT04096638 (Evaluating Safety and Efficacy of SB 11285 Alone and in Combination With Atezolizumab in Patients With Advanced Solid Tumors).
Investigational
Matched Description: … SB 11285 is a second-generation Stimulator of Interferon Genes (STING) agonist. ... L45123] SB 11285 is under investigation in clinical trial NCT04096638 (Evaluating Safety and Efficacy of …
Tralesinidase alfa
Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. It is being investigated for the treatment of mucopolysaccharidosis type IIIB (MPS IIIB), also known as Sanfilippo syndrome B.
Investigational
Matched Description: … Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human ... It is being investigated for the treatment of mucopolysaccharidosis type IIIB (MPS IIIB), also known …
SIG-007
SIG-007 is a gene therapy that consists of cells that are genetically modified with a non-viral vector to express human alpha-galactosidase A. Developed by Sigilon Therapeutics, t is being investigated for the treatment of Fabry Disease.
Investigational
Matched Description: … Developed by Sigilon Therapeutics, t is being investigated for the treatment of Fabry Disease. ... SIG-007 is a gene therapy that consists of cells that are genetically modified with a non-viral vector …
OTL-102
OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human gp91phox gene. It is being investigated for the treatment of X-linked chronic granulomatous disease.
Investigational
Matched Description: … It is being investigated for the treatment of X-linked chronic granulomatous disease. ... OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells …
Inactivated SARS-Cov-2 Vaccine
Developed by Sinopharm's Wuhan Institute of Biological Products co., this vaccine consists of the WIV04 strain of SARS-CoV-2. This strain was isolated from a patient in Wuhan, cultivated in a Vero cell line, and then subsequently inactivated using B-propiolactone. Double-blind, randomized, placebo-controlled phase 1 (96 participants) and phase 2 (224...
Investigational
Matched Description: … strain of SARS-CoV-2. ... Developed by Sinopharm's Wuhan Institute of Biological Products co., this vaccine consists of the WIV04 ... [A220158] Results from these trials showed low rates of adverse reactions and demonstrated immunogenicity …
Aloe vera leaf
Aloe describes a genus including over 500 species of flowering succulent plants that grow in the Southern peninsula and various islands. Aloe vera, or Aloe barbadensis miller, is the most common species of Aloe that is cultivated for agricultural and medical purposes. It is a perennial succulent xerophyte with elongated...
Experimental
Matched Description: … Aloe describes a genus including over 500 species of flowering succulent plants that grow in the Southern ... While aloe vera has a long history of commercial uses, it is still widely used in cosmetic, food and ... The active constituents of aloe vera include polysaccharides with protective effects on skin, as they …
Motexafin lutetium
Motexafin lutetium (MLu) is a second-generation photosensitizer for photodynamic therapy (PDT) of cancer. It belongs to the family of drugs called metallotexaphyrins. Also called lutetium texaphyrin. Motexafin lutetium is a pentadentate aromatic metallotexaphyrin with photosensitizing properties.
Investigational
Matched Description: … It belongs to the family of drugs called metallotexaphyrins. Also called lutetium texaphyrin. ... Motexafin lutetium (MLu) is a second-generation photosensitizer for photodynamic therapy (PDT) of cancer …
Ripertamab
Ripertamab is under investigation in clinical trial NCT02772822 (A Study Comparing the Efficiency and Safety of S-chop(cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated Cd20(cluster of Differentiation Antigen 20)-positive DLBCL Patients).
Investigational
Matched Description: … Ripertamab is under investigation in clinical trial NCT02772822 (A Study Comparing the Efficiency and Safety of ... cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated Cd20(cluster of …
Velsecorat
Velsecorat is under investigation in clinical trial NCT02479412 (A Multiple Dosing (14 Days) Study to Assess Efficacy and Safety of Three Dose Levels of AZD7594, Given Once Daily by Inhalation, in Patients With Mild to Moderate Asthma).
Investigational
Matched Description: … Three Dose Levels of AZD7594, Given Once Daily by Inhalation, in Patients With Mild to Moderate Asthma ... investigation in clinical trial NCT02479412 (A Multiple Dosing (14 Days) Study to Assess Efficacy and Safety of …
Ginsenoside Rb1
Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng). Ginsenosides have been the target of research, as they are viewed as the active compounds behind the claims of ginseng's efficacy. Because ginsenosides appear to affect multiple pathways, their effects are complex...
Nutraceutical
Matched Description: … claims of ginseng's efficacy. ... Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant ... Ginsenosides have been the target of research, as they are viewed as the active compounds behind the …
Mequitazine
Mequitazine is a histamine H1 antagonist (antihistamine). It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory...
Experimental
Matched Description: … It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal ... It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay …
Allogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells
ORBCEL-C™ is the trade name of a product composed of highly purified stromal cells derived from the human umbilical cord. The isolated cells are expanded in culture and are able to be used allogenically -- meaning that one donor’s cells can be given to other unrelated patients. These cells are...
Investigational
Matched Description: … ORBCEL-C™ is the trade name of a product composed of highly purified stromal cells derived from the human ... Enrichment of CD362 expression in MSCs is being investigated for its role in immune modulation of injured ... Regarding the modifications of these UC-MSCs, CD362, also known as syndecan-2, is a surface marker identified …
Displaying drugs 10526 - 10550 of 12589 in total