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Displaying drugs 10576 - 10600 of 11986 in total
Chlorotoxin I-131
Chlorotoxin I-131 is investigated in clinical trials for treating brain cancer. Chlorotoxin I-131 binds to and reduces the activity of a matrix metalloproteinase (MMP) that regulates functioning of the chloride channels on cell membranes. Chlorotoxin is a small 36-amino-acid peptide that selectively binds to glioma cells but not normal brain...
Investigational
Matched Iupac: … {2-[4-(1,2-diphenylbutyl)phenoxy]ethyl}dimethylamine …
N-(ethoxycarbonyl)-L-leucine
Experimental
Matched Iupac: … (2S)-2-[(ethoxycarbonyl)amino]-4-methylpentanoic acid …
1,1,1-TRIFLUORO-3-(OCTYLTHIO)ACETONE
Experimental
Matched Iupac: … 1,1,1-trifluoro-3-(octylsulfanyl)propan-2-one …
Nisoxetine
Nisoxetine is a selective norepinephrine reuptake inhibitor (SNRI) developed in the 1970s. It was originally investigated as an antidepressant but has no current clinical applications aside from being a research standard SNRI. It has been used to research obesity and energy balance, and exerts some local analgesia effects.
Experimental
Matched Iupac: … [3-(2-methoxyphenoxy)-3-phenylpropyl](methyl)amine …
Tedatioxetine
Tedatioxetine has been used in trials studying the treatment of Major Depressive Disorder.
Investigational
Matched Iupac: … 4-{2-[(4-methylphenyl)sulfanyl]phenyl}piperidine …
Tributyrin
Tributyrin has been used in trials studying the treatment of Prostate Cancer and Unspecified Adult Solid Tumor, Protocol Specific.
Investigational
Matched Iupac: … 1,3-bis(butanoyloxy)propan-2-yl butanoate …
Acetylglycinamide chloral hydrate
Experimental
Matched Iupac: … 2,2,2-trichloroethane-1,1-diol; 2-acetamidoacetic acid …
Diclofop-methyl
Herbicide for control of wild oat & foxtails in cereal crops.
Experimental
Matched Iupac: … methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate …
Ampreloxetine
Ampreloxetine is under investigation in clinical trial NCT03750552 (Clinical Effect of TD-9855 for Treating snOH in Subjects With Primary Autonomic Failure).
Investigational
Matched Iupac: … 4-{2-[(2,4,6-trifluorophenoxy)methyl]phenyl}piperidine …
GED-0507-34-Levo
GED-0507-34-Levo is under investigation in clinical trial NCT02808390 (Efficacy and Safety Study of Ged-0507-34-levo for Treatment of UC).
Investigational
Matched Iupac: … (2S)-3-(4-aminophenyl)-2-methoxypropanoic acid …
Domoic Acid
Experimental
Matched Iupac: … (2S,3S,4S)-4-[(2Z,4E,6R)-6-carboxy-6-methylhexa-2,4-dien-2-yl]-3-(carboxymethyl)pyrrolidine-2-carboxylic …
ZK-806711
Experimental
Matched Iupac: … {amino[7-({6-[(1-ethanimidoylpiperidin-4-yl)oxy]-2-methyl-1H-1,3-benzodiazol-1-yl}methyl)naphthalen-2 …
AL5300
Experimental
Matched Iupac: … (4R)-4-hydroxy-1,1-dioxo-2-[(thiophen-2-yl)methyl]-2H,3H,4H-1lambda6-thieno[3,2-e][1,2]thiazine-6-sulfonamide …
Ralimetinib
Ralimetinib has been used in trials studying the treatment of Postmenopausal, Advanced Cancer, Adult Glioblastoma, Fallopian Tube Cancer, and Metastatic Breast Cancer, among others.
Investigational
Matched Iupac: … 2-amine ... 5-[2-tert-butyl-5-(4-fluorophenyl)-1H-imidazol-4-yl]-3-(2,2-dimethylpropyl)-3H-imidazo[4,5-b]pyridin- …
Roniciclib
Roniciclib has been investigated for the treatment of Small Cell Lung Carcinoma.
Investigational
Matched Iupac: … [cyclopropyl({4-[(4-{[(2R,3R)-3-hydroxybutan-2-yl]oxy}-5-(trifluoromethyl)pyrimidin-2-yl)amino]phenyl …
ONO-8539
ONO-8539 is under investigation in clinical trial NCT01707901 (A Study of the Effect of ONO-8539 on Oesophageal Pain Hypersensitivity in Patients With Non-erosive Reflux Disease).
Investigational
Matched Iupac: … 3-methyl-4-[({6-[N-(2-methylpropyl)1,3-thiazole-2-sulfonamido]-2,3-dihydro-1H-inden-5-yl}oxy)methyl]benzoic …
ARRY-502
ARRY-502 is under investigation in clinical trial NCT01561690 (A Study of ARRY-502 in Patients With Persistent Asthma).
Investigational
Matched Iupac: … (4S)-6-chloro-7-(4-{[2-(4-chloro-2-methoxyphenyl)ethyl]carbamoyl}phenoxy)-3,4-dihydro-2H-1-benzopyran …
V116517
V116517 is under investigation in clinical trial NCT01688947 (Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Postherpetic Neuralgia (PHN)).
Investigational
Matched Iupac: … 3-chloro-5-[(1S)-1,2-dihydroxyethyl]-N-[5-(trifluoromethyl)pyridin-2-yl]-1',2',3',6'-tetrahydro-[2,4' …
Poseltinib
Poseltinib is under investigation in clinical trial NCT02628028 (A Study of LY3337641 in Rheumatoid Arthritis).
Investigational
Matched Iupac: … N-{3-[(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}furo[3,2-d]pyrimidin-4-yl)oxy]phenyl}prop-2-enamide …
Imetelstat
Imetelstat is under investigation in clinical trial NCT01916187 (Imetelstat Given Intravenously Alone and With Standard 13-Cis-Retinoic Acid in Children With Neuroblastoma).
Investigational
Matched Iupac: … )amino]oxolan-2-yl]methoxy}(sulfanyl)phosphoryl)amino]-5-(6-amino-9H-purin-9-yl)oxolan-2-yl]methoxy}( ... -1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}(sulfanyl)phosphoryl)amino]-5-(2-amino-6-oxo-6,9 ... )amino]-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methyl 3-hexadecanamido-2- ... -9-yl)oxolan-2-yl]methoxy}(sulfanyl)phosphoryl)amino]-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)oxolan ... sulfanyl)phosphoryl)amino]-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)oxolan-2-yl]methoxy}(sulfanyl)phosphoryl …
Ganglioside GM1
Investigational
Matched Iupac: … (2S,4S,5R,6R)-2-{[(2S,3R,4R,5S,6R)-2-{[(2R,3S,4R,5R,6R)-4,5-dihydroxy-6-{[(2S,3R,4E)-3-hydroxy-2-octadecanamidooctadec ... )-4-{[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-3-hydroxy-6-(hydroxymethyl ... )oxan-4-yl]oxy}-5-acetamido-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid ... -4-en-1-yl]oxy}-2-(hydroxymethyl)oxan-3-yl]oxy}-5-{[(2S,3R,4R,5R,6R)-3-acetamido-5-hydroxy-6-(hydroxymethyl …
Fusicoccin
Experimental
Matched Iupac: … (2S)-2-[(1E,3R,4S,8R,9R,10R,11S,14S)-8-{[(2S,3R,4S,5R,6R)-4-(acetyloxy)-3,5-dihydroxy-6-{[(2-methylbut ... -3-en-2-yl)oxy]methyl}oxan-2-yl]oxy}-4,9-dihydroxy-14-(methoxymethyl)-3,10-dimethyltricyclo[9.3.0.0^{ …
Displaying drugs 10576 - 10600 of 11986 in total