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Displaying drugs 10676 - 10700 of 11083 in total
Butafenacil is under investigation in clinical trial NCT03760328 (Effect of Upper Airway Stimulation in Patients With Obstructive Sleep Apnea).
Investigational
Matched Iupac: … prop-2-en-1-yl 2-{2-chloro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl ... ]benzoyloxy}-2-methylpropanoate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
ALK-4290 is under investigation in clinical trial NCT03558061 (Evaluate the Effects and Safety of ALK4290 in Patients With Newly Diagnosed Wet Age-Related Macular Degeneration).
Investigational
Matched Iupac: … 2-[(2R)-1-{1-[(4-chloro-3-methylphenyl)methyl]piperidin-4-yl}-5-oxopyrrolidine-2-amido]-N,N,6-trimethylpyridine …
Acebilustat is under investigation in clinical trial NCT01748838 (Phase 1 Study Assessing the Safety and Tolerability of CTX-4430).
Investigational
Matched Iupac: … 4-{[(1S,4S)-5-({4-[4-(1,3-oxazol-2-yl)phenoxy]phenyl}methyl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]methyl …
Matched Description: … Acebilustat is under investigation in clinical trial NCT01748838 (Phase 1 Study Assessing the Safety …
Glucoraphanin is under investigation in clinical trial NCT01879878 (Pilot Study Evaluating Broccoli Sprouts in Advanced Pancreatic Cancer [POUDER Trial]).
Investigational
Matched Iupac: … {[(E)-(5-methanesulfinyl-1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanyl}pentylidene …
Famprofazone is a nonsteroidal anti-inflammatory agent found in combination products such as ‘Gewodin’ which is marketed in Taiwan. It is important to note that the drug is metabolized to methamphetamine and amphetamine in the body and can lead to positive tests results for illicit drug use.[A236369,L34724] Famprofazone is included in...
Experimental
Matched Iupac: … 1-methyl-5-{[methyl(1-phenylpropan-2-yl)amino]methyl}-2-phenyl-4-(propan-2-yl)-2,3-dihydro-1H-pyrazol ... -3-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Iupac: … 2-{[(2S)-4-phenyl-2-(sulfanylmethyl)butanoyl]imino}-2-{5-[(1H-1,2,3,4-tetrazol-1-yl)methyl]thiophen-2
Experimental
Matched Iupac: … 7-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H,4H,5H-pyrrolo[3,2-d]pyrimidin-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Experimental
Matched Iupac: … (2R)-2-{carboxy[(2S)-2-carboxy-2-(4-hydroxyphenyl)acetamido]methoxymethyl}-5-methylidene-5,6-dihydro- …
Garenoxacin, a quinolone antibiotic, is being investigated for the treatment of gram-positive and gram-negative bacterial infections.
Investigational
Matched Iupac: … 1-cyclopropyl-8-(difluoromethoxy)-7-[(1R)-1-methyl-2,3-dihydro-1H-isoindol-5-yl]-4-oxo-1,4-dihydroquinoline ... -3-carboxylic acid …
Matched Salts cas: … 223652-90-2
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Azelnidipine is a dihydropyridine calcium channel blocker. It is marketed by Daiichi-Sankyo pharmaceuticals, Inc. in Japan. It has a gradual onset of action and produces a long-lasting decrease in blood pressure, with only a small increase in heart rate, unlike some other calcium channel blockers . It is currently being...
Investigational
Matched Iupac: … 3-[1-(diphenylmethyl)azetidin-3-yl] 5-propan-2-yl 2-amino-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Rociletinib has been used in trials studying the treatment and prevention of Nonsmall Cell Lung Cancer, Non-small Cell Lung Cancer, and Locally Advanced or Metastatic Non-small Cell Lung Cancer.
Investigational
Matched Iupac: … N-{3-[(2-{[4-(4-acetylpiperazin-1-yl)-2-methoxyphenyl]amino}-5-(trifluoromethyl)pyrimidin-4-yl)amino] ... phenyl}prop-2-enamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Eltanolone is under investigation in clinical trial NCT02603926 (Treatment of Fragile-X Associated Tremor/Ataxia Syndrome (FXTAS) With Allopregnanolone).
Investigational
Matched Iupac: … 1-[(1S,2S,5R,7R,10R,11S,14S,15S)-5-hydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan-14-yl ... ]ethan-1-one …
Zamicastat has been used in trials studying the treatment of Hypertension and Chronic Heart Failure.
Investigational
Matched Iupac: … 5-[2-(benzylamino)ethyl]-1-[(3R)-6,8-difluoro-3,4-dihydro-2H-1-benzopyran-3-yl]-2,3-dihydro-1H-imidazole ... -2-thione …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Cenerimod has been used in trials studying the treatment of Systemic Lupus Erythematosus.
Investigational
Matched Iupac: … (2S)-3-{4-[5-(2-cyclopentyl-6-methoxypyridin-4-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy}propane …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Iupac: … (1S,2R,10R,11S,14R,15S)-5-(cyclopentyloxy)-14-ethynyl-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca …
HIV Integrase Inhibitor is under investigation in clinical trial NCT00397566 (A Multiple Ascending Dose Study of BMS-707035 in HIV-1 Infected Subjects).
Investigational
Matched Iupac: … 2-(1,1-dioxo-1lambda6,2-thiazinan-2-yl)-N-[(4-fluorophenyl)methyl]-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine …
Matched Description: … under investigation in clinical trial NCT00397566 (A Multiple Ascending Dose Study of BMS-707035 in HIV-1
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Sodelglitazar is under investigation in clinical trial NCT00196989 (Study in People With Type 2 Diabetes).
Investigational
Matched Iupac: … 2-{4-[({2-[2-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl}methyl)sulfanyl]-2-methylphenoxy ... }-2-methylpropanoic acid …
Matched Description: … Sodelglitazar is under investigation in clinical trial NCT00196989 (Study in People With Type 2 Diabetes …
Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase).
Investigational
Matched Synonyms: … Iduronate 2-sulfatase (a-l-iduronate sulfate sulfatase), human proenzyme produced in cho cells (glycoform …
Experimental
Matched Iupac: … -2-yl]oxy}-5,6-dihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-3,4-dihydroxy-6-methyloxan-2-yl]oxy ... -dihydroxy-6-(hydroxymethyl)-5-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan ... (2R,3R,4S,5S,6R)-6-({[(2S,3R,4R,5S,6R)-5-{[(2R,3R,4S,5S,6R)-5-{[(1S,4R,5R,6S)-4-{[(2S,3R,4R,5S,6R)-3,4 ... }-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxane-2,3,4,5-tetrol …
Bambermycins are antibiotic complexes which are retrieved from the organism, Streptomyces bambergiensis. They are used as an additive in food ingested by chickens and swine. The bambermycin complex of antibiotics consists primarily of moenomycins A and C.
Vet approved
Matched Iupac: … -hydroxy-6-methyl-5-{[(2R,3R,4S,5R,6S)-3,4,5-trihydroxy-6-[(2-hydroxy-5-oxocyclopent-1-en-1-yl)carbamoyl ... (2S,3S,4R,5R,6R)-4-(carbamoyloxy)-5-{[(2S,3R,4R,5S,6R)-3-acetamido-5-{[(2S,3R,4R,5S,6R)-3-acetamido-4 ... -pentamethyl-12-methylideneicosa-3,7,14,18-tetraen-1-yl]oxy}propoxy]phosphoryl}oxy)-3-methyloxane-2-carboxylic ... 2-yl]oxy}methyl)oxan-2-yl]oxy}-3-hydroxy-6-({hydroxy[(2R)-2-hydroxy-3-oxo-3-{[(3E,7E,14E)-4,9,9,15,19 ... ]oxan-2-yl]oxy}oxan-2-yl]oxy}-4-hydroxy-6-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan- …
Doramapimod is a P38 MAP kinase inhibitor.
Investigational
Matched Iupac: … 3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-1-{4-[2-(morpholin-4-yl)ethoxy]naphthalen-1-yl}urea …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Investigational
Matched Iupac: … (2S,3R,5S)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-2-(hydroxymethyl)oxolan-3-yl (2S)-2-amino-3-methylbutanoate …
Danofloxacin is an antibiotic agent from the family of the fluoroquinolones used in veterinary medicine.
Experimental
Vet approved
Matched Iupac: … 1-cyclopropyl-6-fluoro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]-4-oxo-1,4-dihydroquinoline ... -3-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
JNJ-40346527 has been used in trials studying the treatment of Health and Arthritis, Rheumatoid.
Investigational
Matched Iupac: … 5-cyano-N-[2-(4,4-dimethylcyclohex-1-en-1-yl)-6-(2,2,6,6-tetramethyloxan-4-yl)pyridin-3-yl]-1H-imidazole ... -2-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
GW810781 is under investigation in clinical trial NCT00046332 (A Study Comparing 4 Doses of GW810781 Versus Placebo in Hiv-infected Patients).
Investigational
Matched Iupac: … (2Z)-1-{5-[(4-fluorophenyl)methyl]furan-2-yl}-3-hydroxy-3-(1H-1,2,4-triazol-3-yl)prop-2-en-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 10676 - 10700 of 11083 in total