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Displaying drugs 1051 - 1075 of 1863 in total
Allopurinol riboside is a nucleoside analogue of allopurinol with a beta-D-ribofuranosyl moiety at the 1-position.
Investigational
Matched Synonyms: … 4h-pyrazolo(3,4-d)pyrimidin-4-one, 1,5-dihydro-1-.beta.-d-ribofuranosyl- …
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one …
Matched Description: … Allopurinol riboside is a nucleoside analogue of [allopurinol] with a beta-D-ribofuranosyl moiety at …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Synthetic guanethidine derivative that locates phaeochromocytomas and neuroblastomas. The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline. Iodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture. Images are produced by a I123 MIBG scintigraphy. FDA approved...
Approved
Investigational
Matched Description: … Synthetic guanethidine derivative that locates phaeochromocytomas and neuroblastomas. …
Matched Categories: … Indicators and Reagents …
Matched Products: … IOBENGUANO [131 I] GE HEALTHCARE D
Methadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist. As a full MOR agonist, methadone mimics the natural effects of the body's opioids, endorphins, and enkephalins through the release of neurotransmitters involved in pain transmission. It also has a...
Approved
Matched Synonyms: … dl-Methadone …
Matched Description: … Methadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate ... σ-opioid receptors, as an antagonist of the N-methyl-D-aspartate (NMDA) receptor, and as an inhibitor ... ; in particular, methadone has a lower risk of neuropsychiatric toxicity compared to other opioids (due
Matched Products: … Metadol-D ... Methadone Hydrocloride dye-free, sugar-free, unflavored …
Indopan (alpha-methyltryptamine) is a stimulant and psychoactive drug which produces effects similar to 3,4-methylenedioxy-N-methylamphetamine (MDMA), despite being structurally dissimilar. It was developed in the 1960's by Upjohn with the intention for use as an antidepressant. In the 1990's, indopan became regulated as a Schedule I controlled substance in the United...
Experimental
Illicit
Matched Synonyms: … DL-3-(2-Aminopropyl)indole ... alpha-methyltryptamine ... alpha-Methyl-1H-indole-3-ethanamine …
Matched Description: … Indopan (alpha-methyltryptamine) is a stimulant and psychoactive drug which produces effects similar …
A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Approved
Matched Synonyms: … 2-Methyl-alpha-propylaminopropionanilide ... alpha-n-Propylamino-2-methylpropionanilide ... o-Methyl-alpha-propylaminopropionanilide …
Matched Mixtures name: … ANESTIDERM DUO - LIDOCAINA +PRILOCAINA CREMA ... Lidocaine and Prilocaine ... Lidocaine and Prilocaine …
Naloxone is an opioid antagonist medication used to block or reverse the effects of opioid drugs, particularly within the setting of drug overdoses which are rapidly becoming a leading cause of death worldwide. More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist,...
Approved
Vet approved
Matched Description: … Due to its short duration of action, persons injected with naloxone should be monitored for responsiveness ... , and even death. ... Frequently also carried by medical and emergency personnel and at events known to be associated with …
Matched Mixtures name: … TILIDIN HEXAL COMP D-PUMPE ... Bupensan Duo 4 mg/1 mg-Sublingualtabletten ... Bupensan Duo 8 mg/2 mg-Sublingualtabletten …
Matched Categories: … Alimentary Tract and Metabolism ... tilidine and naloxone ... oxycodone and naloxone ... pentazocine and naloxone ... hydromorphone and naloxone …
Matched Products: … DBL NALOXONE HYDROCHLORIDE INJECTION ... NALOKSON HIDROKLORUR ENJ.10AMP(D)(E …
Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in 1996. It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. Brimonidine displays a higher selectivity toward the alpha-2 adrenergic receptors than clonidine or...
Approved
Matched Description: … Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in ... Early treatment and management of glaucoma, which predominantly involves the lowering of intraocular ... Ophthalmically, brimonidine is used to lower intraocular pressure by reducing aqueous humor production and
Matched Mixtures name: … Brimonidine Tartrate and Timolol Maleate ... BRIMONIDINE TARTRATE and TIMOLOL MALEATE ... Brimonidine Tartrate and Timolol Maleate …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Decongestants and Antiallergics ... Skin and Mucous Membrane Agents ... Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists …
Matched Products: … Dom-brimonidine ... Alpha-Vision sine 2 mg/ml Augentropfen, Lösung im Einzeldosisbehältnis ... TARTRATO DE BRIMONIDINA0.2 % …
Macadamia seed oil glycereth-8 esters is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Name: … Macadamia seed oil glycereth-8 esters …
Matched Description: … Macadamia seed oil glycereth-8 esters is a plant/plant extract used in some OTC (over-the-counter) products …
Taliglucerase alfa is the recombinant active form of the human lysosomal enzyme, β-glucocerebrosidase. It was approved in 2012 and is marketed under the name Elelyso for use in patients with type 1 Gaucher's disease.
Approved
Investigational
Matched Synonyms: … prGC-D
Matched Description: … It was approved in 2012 and is marketed under the name Elelyso for use in patients with type 1 Gaucher's …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Experimental
Matched Name: … Tosyl-D-Proline …
Investigational
Matched Synonyms: … Cyclo(l-arginylglycyl-l-.alpha. ... -aspartyl-d-phenylalanyl-n6-(2,6-anhydro-7-deoxy-7-((2-(4-(3-(fluoro-18f)propyl)-1h-1,2,3-triazol-1-yl …
Experimental
Matched Name: … N-Alpha-(2-Naphthylsulfonyl)-N-(3-Amidino-L-Phenylalaninyl)-D-Pipecolinic Acid …
Approved
Investigational
Matched Synonyms: … alpha-Narcotine …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives …
Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined with other drugs in the brand names Nethaprin and Dalmacol . It was previously available as both the free base and as the hydrochloride salt manufactured by Sanofi-Aventis (now Sanofi) has been discontinued . Ethylephedrine is...
Approved
Matched Synonyms: … alpha-(1-(ethylmethylamino)ethyl)benzyl alcohol …
Matched Description: … with other drugs in the brand names Nethaprin [A32757] and Dalmacol [L2568]. ... Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined ... It was previously available as both the free base and as the hydrochloride salt manufactured by Sanofi-Aventis …
2'-fluoro-5-ethylarabinosyluracil (FAU) has been used in trials studying the treatment of Small Intestine Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma, and Recurrent Mantle Cell Lymphoma, among others.
Investigational
Matched Synonyms: … 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil ... 2'-Fluoro-5-ethyl-1-beta-D-arabinofuranosyluracil …
Matched Description: … Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma, and
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Investigational
Matched Synonyms: … H-(4-amino-3-iodo)-d-phe-c(cys-(3-iodo)-tyr-d-trp-lys-val-cys)-thr-nh2 ... H-(4-amino-3-iodo)-D-Phe-c[Cys-(3-iodo)-Tyr-D-Trp-Lys-Val-Cys]-Thr-NH2 ... L-threoninamide, 4-amino-3-iodo-d-phenylalanyl-l-cysteinyl-3-iodo-l-tyrosyl-d-tryptophyl-l-lysyl-l-valyl-l-cysteinyl …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
WP-1122 is a prodrug of 2-deoxy-D-glucose (2-DG). It was granted FDA orphan designation for the treatment of glioblastoma multiforme.
Investigational
Matched Synonyms: … 3,6-di-O-acetyl-2-deoxy-D-glucopyranose ... an acetic acid diester of 2-deoxy-D-glucose …
Matched Iupac: … (3R,4R,5R)-6-(acetyloxy)-4,5-dihydroxy-1-oxohexan-3-yl acetate
Matched Description: … WP-1122 is a prodrug of 2-deoxy-D-glucose (2-DG). …
Experimental
Matched Synonyms: … alpha-Methylalanine ... alpha-Aminoisobutyric acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … 1-N-acetyl-beta-D-glucosamine …
Matched Name: … N-beta-D-glucopyranosylacetamide …
Experimental
Investigational
Matched Synonyms: … D&C Blue No. 6 …
A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, etc. It has been used therapeutically to decrease capillary fragility.
Approved
Experimental
Investigational
Matched Synonyms: … 3-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy …
Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.[L8384,L8387,L8390] Lisinopril and captopril are the only ACEIs that are not prodrugs. It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system.[A184781,A184808,A184817] ACEIs are commonly used as a...
Approved
Investigational
Matched Description: … [L8384,L8387,L8390] Lisinopril and [captopril] are the only ACEIs that are not prodrugs. ... Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and
Matched Mixtures name: … Co-Acetan - Tabletten ... Co-Acetan mite - Tabletten ... LISINOPRIL E IDROCLOROTIAZIDE DOC GENERICI …
Matched Categories: … ACE Inhibitors and Diuretics ... ACE Inhibitors and Calcium Channel Blockers ... Amino Acids, Peptides, and Proteins ... lisinopril and diuretics ... lisinopril and amlodipine …
Matched Products: … Dom-lisinopril ... LISINOPRIL DOC GENERICI ... Acetan 5 mg - Tabletten …
A chemically stable, cytidine analog that displays anti-tumor properties. It acts as a transition state analog inhibitor of cytidine deaminase by binding to the active site as covalent hydrates. Also shown to inhibit DNA methylation and tumor growth both in vitro and in vivo.
Experimental
Matched Synonyms: … 1-beta-D-ribofuranosyl-2(1H)-pyrimidinone ... Pyrimidin-2-one beta-D-ribofuranoside ... 1-beta-D-ribofuranosylpyrimidin-2(1H)-one …
Matched Description: … Also shown to inhibit DNA methylation and tumor growth both in vitro and in vivo. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Synonyms: … Methyl 4-thio-β-D-glucopyranoside …
Matched Name: … Methyl 4-thio-beta-D-glucopyranoside …
Experimental
Matched Synonyms: … 4-Phospho-D-Erythronate …
Matched Name: … 4-phospho-D-erythronic acid …
Displaying drugs 1051 - 1075 of 1863 in total