Displaying drugs 1051 - 1075 of 1634 in total
({3-[1-(4-Hydroxy-2-oxo-2H-chromen-3-yl)-propyl]-phenylcarbamoyl}-methyl)-carbamic acid tert-butyl ester
Experimental
Matched Synonyms: … tert-butyl N-[({3-[(1S)-1-(4-hydroxy-2-oxo-2H-chromen-3-yl)propyl]phenyl}carbamoyl)methyl]carbamate …
Matched Iupac: … tert-butyl N-[({3-[(1S)-1-(4-hydroxy-2-oxo-2H-chromen-3-yl)propyl]phenyl}carbamoyl)methyl]carbamate …
Matched Iupac: … tert-butyl N-[({3-[(1S)-1-(4-hydroxy-2-oxo-2H-chromen-3-yl)propyl]phenyl}carbamoyl)methyl]carbamate …
Soraprazan
Investigational
Matched Synonyms: … (7r,8r,9r)-7-(2-methoxyethoxy)-2,3-dimethyl-9-phenyl-7,8,9,10-tetrahydroimidazo(1,2-h)(1,7)naphtyridin …
Matched Iupac: … (7R,8R,9R)-7-(2-methoxyethoxy)-2,3-dimethyl-9-phenyl-7H,8H,9H,10H-imidazo[1,2-h]1,7-naphthyridin-8-ol …
Matched Iupac: … (7R,8R,9R)-7-(2-methoxyethoxy)-2,3-dimethyl-9-phenyl-7H,8H,9H,10H-imidazo[1,2-h]1,7-naphthyridin-8-ol …
APT-101
Investigational
Matched Synonyms: … (S)-3-(1-Cyclopentyl-5-(2-(trifluoromethyl)phenyl)-1H-pyrazole-3-carboxamido)-5-(3,3-difluoropiperidin …
Matched Iupac: … (3S)-3-({1-cyclopentyl-5-[2-(trifluoromethyl)phenyl]-1H-pyrazol-3-yl}formamido)-5-(3,3-difluoropiperidin …
Matched Iupac: … (3S)-3-({1-cyclopentyl-5-[2-(trifluoromethyl)phenyl]-1H-pyrazol-3-yl}formamido)-5-(3,3-difluoropiperidin …
Ritivixibat
Investigational
Matched Synonyms: … 3-([3,3-dibutyl-7-(methylsulfanyl)-1,1-dioxo-5-phenyl-2,3,4,5-tetrahydro-1H-1Lambda6,2,5-benzothiadiazepin …
Matched Iupac: … 3-{[3,3-dibutyl-7-(methylsulfanyl)-1,1-dioxo-5-phenyl-2,3,4,5-tetrahydro-1lambda6,2,5-benzothiadiazepin …
Matched Iupac: … 3-{[3,3-dibutyl-7-(methylsulfanyl)-1,1-dioxo-5-phenyl-2,3,4,5-tetrahydro-1lambda6,2,5-benzothiadiazepin …
(S)-Fluoxetine
An N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has S configuration (the antidepressant drug fluoxetine is a racemate comprising equimolar amounts of (R)- and (S)-fluoxetine).
Experimental
Matched Synonyms: … (S)-N-methyl-3-(4-trifluoromethylphenyloxy)-3-(phenyl)propylamine ... (S)-N-methyl-3-phenyl-3-[(α,α,α-trifluoro-p-tolyl)oxy]propylamine …
Matched Iupac: … methyl[(3S)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]amine …
Matched Description: … drug fluoxetine is a racemate comprising equimolar amounts of (R)- and (S)-fluoxetine). ... An N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has S configuration (the antidepressant …
Matched Iupac: … methyl[(3S)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]amine …
Matched Description: … drug fluoxetine is a racemate comprising equimolar amounts of (R)- and (S)-fluoxetine). ... An N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has S configuration (the antidepressant …
Oteseconazole
Oteseconazole is an azole metalloenzyme inhibitor that targets fungal CYP51. CYP51, also known as 14α demethylase, participates in the formation of ergosterol, a compound that plays a vital role in the integrity of cell membranes.[L41635,A247020] By binding and inhibiting CYP51, oteseconazole is active against most microorganisms associated with recurrent vulvovaginal...
Approved
Investigational
Matched Synonyms: … (R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin ... Pyridineethanol, α-(2,4difluorophenyl)-β β-difluoro- α-(1H-tetrazol-1-ylmethyl)-5-(4-(2,2,2-trifluoroethoxy)phenyl …
Matched Iupac: … 2R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-1,2,3,4-tetrazol-1-yl)-1-{5-[4-(2,2,2-trifluoroethoxy)phenyl …
Matched Description: … [L41635,A247020] By binding and inhibiting CYP51, oteseconazole is active against most microorganisms ... Candida glabrata_, _Candida krusei_, _Candida parapsilosis_, _Candida tropicalis_, _Candida lusitaniae_ and ... L41635] Unlike previous-generation azole antifungals, oteseconazole has a high selectivity for CYP51 and …
Matched Categories: … Triazole and tetrazole derivatives …
Matched Iupac: … 2R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-1,2,3,4-tetrazol-1-yl)-1-{5-[4-(2,2,2-trifluoroethoxy)phenyl …
Matched Description: … [L41635,A247020] By binding and inhibiting CYP51, oteseconazole is active against most microorganisms ... Candida glabrata_, _Candida krusei_, _Candida parapsilosis_, _Candida tropicalis_, _Candida lusitaniae_ and ... L41635] Unlike previous-generation azole antifungals, oteseconazole has a high selectivity for CYP51 and …
Matched Categories: … Triazole and tetrazole derivatives …
Isoeugenol
Isoeugenol is a commonly used fragrance added to many commercially available products, and occurs naturally in the essential oils of plants such as ylang-ylang. It is also a significant dermatologic sensitizer and allergen, and as a result has been restricted to 200 p.p.m. since 1998 according to guidelines issued by...
Approved
Experimental
Matched Synonyms: … 2-methoxy-4-(prop-1-en-1-yl)phenol …
Matched Iupac: … 2-methoxy-4-(prop-1-en-1-yl)phenol …
Matched Description: … in the essential oils of plants such as ylang-ylang. ... It is also a significant dermatologic sensitizer and allergen, and as a result has been restricted to ... Isoeugenol is a commonly used fragrance added to many commercially available products, and occurs naturally …
Matched Iupac: … 2-methoxy-4-(prop-1-en-1-yl)phenol …
Matched Description: … in the essential oils of plants such as ylang-ylang. ... It is also a significant dermatologic sensitizer and allergen, and as a result has been restricted to ... Isoeugenol is a commonly used fragrance added to many commercially available products, and occurs naturally …
2-(2,4-DICHLOROPHENOXY)-5-(PYRIDIN-2-YLMETHYL)PHENOL
Experimental
Matched Name: … 2-(2,4-DICHLOROPHENOXY)-5-(PYRIDIN-2-YLMETHYL)PHENOL …
Matched Iupac: … 2-(2,4-dichlorophenoxy)-5-[(pyridin-2-yl)methyl]phenol …
Matched Iupac: … 2-(2,4-dichlorophenoxy)-5-[(pyridin-2-yl)methyl]phenol …
4-[5-(3-IODO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-1H-IMIDAZOL-4-YL]-PYRIDINE
Experimental
Matched Name: … 4-[5-(3-IODO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-1H-IMIDAZOL-4-YL]-PYRIDINE …
Matched Iupac: … 4-[5-(3-iodophenyl)-2-{4-[(R)-methanesulfinyl]phenyl}-1H-imidazol-4-yl]pyridine …
Matched Iupac: … 4-[5-(3-iodophenyl)-2-{4-[(R)-methanesulfinyl]phenyl}-1H-imidazol-4-yl]pyridine …
Cinnarizine
First synthesized by Janssen Pharmaceuticals in 1955, cinnarizine is an anti-histaminic drug mainly used for the control of vestibular disorders and motion sickness. Cinnarizine is a specific calcium channel blocker that primarily works on the central vestibular system to interfere with the signal transmission between vestibular apparatus of the inner...
Approved
Investigational
Matched Synonyms: … 1-(Diphenylmethyl)-4-(3-phenyl-2-propenyl)piperazine …
Matched Description: … in 1955, cinnarizine is an anti-histaminic drug mainly used for the control of vestibular disorders and ... vestibular system to interfere with the signal transmission between vestibular apparatus of the inner ear and ... viewed as a nootropic drug because of its vasorelaxating abilities (due to calcium channel blockage), which …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Description: … in 1955, cinnarizine is an anti-histaminic drug mainly used for the control of vestibular disorders and ... vestibular system to interfere with the signal transmission between vestibular apparatus of the inner ear and ... viewed as a nootropic drug because of its vasorelaxating abilities (due to calcium channel blockage), which …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Diloxanide furoate
Approved
Matched Synonyms: … 4-(n-methyl-2,2-dichloroacetamido)phenyl 2-furoate …
Matched Iupac: … 4-(2,2-dichloro-N-methylacetamido)phenyl furan-2-carboxylate …
Matched Iupac: … 4-(2,2-dichloro-N-methylacetamido)phenyl furan-2-carboxylate …
Narazaciclib
Narazaciclib is under investigation in clinical trial NCT06351644 (On 123300 (Narazaciclib) and Dexamethasone in Patients With Relapsed And/or Refractory Multiple Myeloma).
Investigational
Matched Synonyms: … Pyrido(2,3-d)pyrimidine-6-carbonitrile, 8-cyclopentyl-7,8-dihydro-2-((4-(4-methyl-1-piperazinyl)phenyl …
Matched Description: … in Patients With Relapsed And/or Refractory Multiple Myeloma). ... Narazaciclib is under investigation in clinical trial NCT06351644 (On 123300 (Narazaciclib) and Dexamethasone …
Matched Description: … in Patients With Relapsed And/or Refractory Multiple Myeloma). ... Narazaciclib is under investigation in clinical trial NCT06351644 (On 123300 (Narazaciclib) and Dexamethasone …
Nandrolone phenpropionate
C18 steroid with androgenic and anabolic properties. It is generally prepared from alkyl ethers of estradiol to resemble testosterone but less one carbon at the 19 position. It is a schedule III drug in the U.S.
Approved
Illicit
Investigational
Matched Synonyms: … Norandrolone phenyl propionate …
Matched Description: … C18 steroid with androgenic and anabolic properties. …
Matched Categories: … Nandrolone and esters ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … C18 steroid with androgenic and anabolic properties. …
Matched Categories: … Nandrolone and esters ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Delpazolid
Delpazolid (LCB01-0371) is under investigation in clinical trial NCT01554995 (A Clinical Study, Randomized, Double-blind, Placebo-controlled, Single Dose Study).
Investigational
Matched Synonyms: … (5R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one ... (5R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)-1,3-oxazolidin ... (R)-3-[3-Fluoro-4-(1-methyl-1,4,5,6-tetrahydro-1,2,4-triazin-4-yl)phenyl]-5(R)-(hydroxymethyl)oxazolidin …
Matched Iupac: … (5R)-3-[3-fluoro-4-(1-methyl-1,4,5,6-tetrahydro-1,2,4-triazin-4-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin …
Matched Iupac: … (5R)-3-[3-fluoro-4-(1-methyl-1,4,5,6-tetrahydro-1,2,4-triazin-4-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin …
Iclepertin
Iclepertin is under investigation in clinical trial NCT05211947 (A Study to Test Long-term Safety of Iclepertin in People With Schizophrenia Who Took Part in a Previous CONNEX Study).
Investigational
Matched Synonyms: … [5-(Methylsulfonyl)-2-[(1R)-2,2,2-trifluoro-1-methylethoxy]phenyl][(1R,5R)-1-[5-(trifluoromethyl)-3-isoxazolyl ... Methanone, (5-(methylsulfonyl)-2-((1r)-2,2,2-trifluoro-1-methylethoxy)phenyl)((1r,5r)-1-(5-(trifluoromethyl …
N-{3-[(4-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMIDIN-2-YL)AMINO]PHENYL}CYCLOPROPANECARBOXAMIDE
Experimental
Matched Name: … N-{3-[(4-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMIDIN-2-YL)AMINO]PHENYL}CYCLOPROPANECARBOXAMIDE …
Matched Iupac: … N-{3-[(4-{[3-(trifluoromethyl)phenyl]amino}pyrimidin-2-yl)amino]phenyl}cyclopropanecarboxamide …
Matched Iupac: … N-{3-[(4-{[3-(trifluoromethyl)phenyl]amino}pyrimidin-2-yl)amino]phenyl}cyclopropanecarboxamide …
1-(4-Cyano-phenyl)-3-[2-(2,6-dichloro-phenyl)-1-imino-ethyl]-thiourea
Experimental
Matched Name: … 1-(4-Cyano-phenyl)-3-[2-(2,6-dichloro-phenyl)-1-imino-ethyl]-thiourea …
5-phenyl-1H-indazol-3-amine
Experimental
Matched Name: … 5-phenyl-1H-indazol-3-amine …
Matched Iupac: … 5-phenyl-1H-indazol-3-amine …
Matched Iupac: … 5-phenyl-1H-indazol-3-amine …
(3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE
Experimental
Matched Name: … (3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE …
N-[4-(AMINOSULFONYL)PHENYL]-2-MERCAPTOBENZAMIDE
Experimental
Matched Name: … N-[4-(AMINOSULFONYL)PHENYL]-2-MERCAPTOBENZAMIDE …
ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE
Experimental
Matched Name: … ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE …
Delamanid
Delamanid is an anti-tuberculosis agent derived from the nitro-dihydro-imidazooxazole class of compounds that inhibits mycolic acid synthesis of bacterial cell wall . It is used in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis (TB) in a combination regimen. Emergence of multidrug-resistant and extensively drug-resistant tuberculosis creates clinical challenges for...
Approved
Investigational
Matched Synonyms: … )phenoxy)methyl)-, (2R)- ... (2R)-2-methyl-6-nitro-2-((4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)methyl)-2,3-dihydroimidazo ... Imidazo(2,1-B)oxazole, 2,3-dihydro-2-methyl-6-nitro-2-((4-(4-(4-(trifluoromethoxy)phenoxy)-1-piperidinyl …
Matched Iupac: … )phenoxy]piperidine ... 1-(4-{[(2R)-2-methyl-6-nitro-2H,3H-imidazo[2,1-b][1,3]oxazol-2-yl]methoxy}phenyl)-4-[4-(trifluoromethoxy …
Matched Description: … response to standardized antituberculosis treatments as [DB00951] and [DB01045]. ... It is used in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis (TB) in ... Emergence of multidrug-resistant and extensively drug-resistant tuberculosis creates clinical challenges …
Matched Iupac: … )phenoxy]piperidine ... 1-(4-{[(2R)-2-methyl-6-nitro-2H,3H-imidazo[2,1-b][1,3]oxazol-2-yl]methoxy}phenyl)-4-[4-(trifluoromethoxy …
Matched Description: … response to standardized antituberculosis treatments as [DB00951] and [DB01045]. ... It is used in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis (TB) in ... Emergence of multidrug-resistant and extensively drug-resistant tuberculosis creates clinical challenges …
Masitinib
Masitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in dogs. It has been available in Europe since 2009, under the brand name Masivet. In the USA it is distributed under the name Kinavet and has been available for veterinaries since 2011.
Investigational
Vet approved
Matched Synonyms: … 4-((4-METHYLPIPERAZIN-1-YL)METHYL)-N-(4-METHYL-3-((4-PYRIDIN-3-YL-1,3-THIAZOL-2-YL)AMINO)PHENYL)BENZAMIDE …
Matched Iupac: … N-(4-methyl-3-{[4-(pyridin-3-yl)-1,3-thiazol-2-yl]amino}phenyl)-4-[(4-methylpiperazin-1-yl)methyl]benzamide …
Matched Description: … In the USA it is distributed under the name Kinavet and has been available for veterinaries since 2011 …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … N-(4-methyl-3-{[4-(pyridin-3-yl)-1,3-thiazol-2-yl]amino}phenyl)-4-[(4-methylpiperazin-1-yl)methyl]benzamide …
Matched Description: … In the USA it is distributed under the name Kinavet and has been available for veterinaries since 2011 …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
KX-2361
Investigational
Matched Synonyms: … 2-pyridineacetamide, n-((3-fluorophenyl)methyl)-5-(4-(4-morpholinyl)phenyl)- …
Matched Iupac: … N-[(3-fluorophenyl)methyl]-2-{5-[4-(morpholin-4-yl)phenyl]pyridin-2-yl}acetamide …
Matched Iupac: … N-[(3-fluorophenyl)methyl]-2-{5-[4-(morpholin-4-yl)phenyl]pyridin-2-yl}acetamide …
Carbenicillin
Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.
Approved
Investigational
Matched Synonyms: … α-phenyl(carboxymethylpenicillin) ... (2S,5R,6R)-6-{[carboxy(phenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Matched Description: … It is susceptible to gastric juice and penicillinase and may damage platelet function. …
Matched Description: … It is susceptible to gastric juice and penicillinase and may damage platelet function. …
Displaying drugs 1051 - 1075 of 1634 in total