Displaying drugs 1051 - 1075 of 1293 in total
AAV9/MFSD8
AAV9/MFSD8 is a gene therapy developed by Neurogene Inc. It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8. It was investigated for the treatment of neuronal ceroid lipofuscinosis type 7.
Investigational
Matched Synonyms: … MFSD8 gene for expression of active human major facilitator superfamily domain containing 8 ... An adeno-associated virus serotype 9 (AAV9) vector with engineered transgene encoding the human CLN7/ …
Matched Description: … It was investigated for the treatment of neuronal ceroid lipofuscinosis type 7. ... CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8. ... It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human …
Matched Description: … It was investigated for the treatment of neuronal ceroid lipofuscinosis type 7. ... CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8. ... It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human …
Humate-P
Investigational
Matched Name: … Humate-P …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins ... Protein Precursors …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins ... Protein Precursors …
Dinutuximab
Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody against GD2, a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues. It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the constant regions...
Approved
Investigational
Matched Synonyms: … WITH HUMAN-MUS MUSCULUS MONOCLONAL CH14.18 LIGHT CHAIN, DIMER ... WITH HUMAN-MUS MUSCULUS MONOCLONAL CH14.18/CHO LIGHT CHAIN, DIMER ... IMMUNOGLOBULIN G1, ANTI-(GANGLIOSIDE GD2) (HUMAN-MUS MUSCULUS MONOCLONAL CH14.18 HEAVY CHAIN), DISULFIDE …
Matched Description: … constant regions of human IgG1 heavy-chain and kappa light-chain. ... on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted ... cis-retinoic acid (RA), for the treatment of pediatric patients with high-risk neuroblastoma who achieve at least …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Proteins ... Blood Proteins …
Matched Description: … constant regions of human IgG1 heavy-chain and kappa light-chain. ... on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted ... cis-retinoic acid (RA), for the treatment of pediatric patients with high-risk neuroblastoma who achieve at least …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Proteins ... Blood Proteins …
West Nile immune globulin
Investigational
Matched Synonyms: … Immune Globulin (Human) containing high titers of West Nile virus antibodies …
HG004
Investigational
Matched Synonyms: … Adeno-associated viral vector serotype 9 (AAV9) containing human RPE65 gene …
Bizaxofusp
Investigational
Matched Synonyms: … Il4-pseudomonas exotoxin fusion protein mdna55 ... Il-4 pseudomonas toxin fusion protein (il-4(38-37)-pe38kdel) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins …
Albumin iodinated I-125 serum
I-125 iodinated albumin is a radiolabeled albumin-based diagnostic agent used in the determination of total blood and plasma volume.
Approved
Matched Synonyms: … Human albumin I-125 ... Human serum albumin I-125 ... Iodinated (125I) human serum albumin …
Matched Description: … iodinated albumin is a radiolabeled albumin-based diagnostic agent used in the determination of total blood and …
Matched Description: … iodinated albumin is a radiolabeled albumin-based diagnostic agent used in the determination of total blood and …
Neisseria meningitidis serogroup b fhbp fusion protein antigen
Approved
Matched Synonyms: … Neisseria meningitidis serogroup B recombinant FHBP fusion protein antigen …
Matched Name: … Neisseria meningitidis serogroup b fhbp fusion protein antigen …
Matched Name: … Neisseria meningitidis serogroup b fhbp fusion protein antigen …
Efanesoctocog alfa
Efanesoctocog alfa (BIVV001) is a recombinant factor VIII (FVIII) analogue fusion protein used for the routine prophylaxis, perioperative management of bleeding and on-demand treatment and control of bleeding episodes in patients with hemophilia A. The use of FVIII replacement products is beneficial in patients with hemophilia A; however, their quality...
Approved
Investigational
Matched Synonyms: … Antihemophilic factor (recombinant), Fc-VWF-XTEN fusion protein-ehtl …
Matched Description: … routine prophylaxis, perioperative management of bleeding and on-demand treatment and control of bleeding ... [A257464] Efanesoctocog alfa was designed to have an extended half-life, and to surpass the half-life ... To extend the half-life of FVIII, efanesoctocog alfa is fused to dimeric Fc, a D'D3 domain of VWF, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins ... Recombinant Proteins ... Recombinant Fusion Proteins …
Matched Description: … routine prophylaxis, perioperative management of bleeding and on-demand treatment and control of bleeding ... [A257464] Efanesoctocog alfa was designed to have an extended half-life, and to surpass the half-life ... To extend the half-life of FVIII, efanesoctocog alfa is fused to dimeric Fc, a D'D3 domain of VWF, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins ... Recombinant Proteins ... Recombinant Fusion Proteins …
GALE-301
GALE-301 is an investigational cancer immunotherapy. It is made up of E39, an immunogenic peptide derived from the folate binding protein (FBP), and an immune adjuvant, granulocyte macrophage-colony stimulating factor (GM-CSF).[A254696,L44166,L44171]
Investigational
Matched Synonyms: … Folate Binding Protein E39 vaccine …
Matched Description: … It is made up of E39, an immunogenic peptide derived from the folate binding protein (FBP), and an immune …
Matched Description: … It is made up of E39, an immunogenic peptide derived from the folate binding protein (FBP), and an immune …
SM-1997
SM-1997 is a protein-free solution derived from calf's blood comprising electrolytes, trace minerals, amino acids, peptides, nucleosides, and nucleotides. It is under investigation for the treatment of cutaneous sulfur mustard-induced injury.
Investigational
Matched Synonyms: … Solution of protein-free hemodialysate of calf blood …
Matched Description: … amino acids, peptides, nucleosides, and nucleotides. ... SM-1997 is a protein-free solution derived from calf's blood comprising electrolytes, trace minerals, …
Matched Description: … amino acids, peptides, nucleosides, and nucleotides. ... SM-1997 is a protein-free solution derived from calf's blood comprising electrolytes, trace minerals, …
Vespula maculifrons venom protein
Vespula maculifrons venom protein is an extract of Vespula maculifrons venom. Vespula maculifrons venom protein is used in allergenic testing.
Approved
Matched Name: … Vespula maculifrons venom protein …
Matched Description: … Vespula maculifrons venom protein is used in allergenic testing. ... Vespula maculifrons venom protein is an extract of Vespula maculifrons venom. …
Matched Categories: … Bee and Wasp Venom …
Matched Description: … Vespula maculifrons venom protein is used in allergenic testing. ... Vespula maculifrons venom protein is an extract of Vespula maculifrons venom. …
Matched Categories: … Bee and Wasp Venom …
Viral Macrophage-Inflammatory Protein
Viral macrophage inflammatory protein-II (vMIP) is a highly basic protein and human chemokine analog encoded by human herpesvirus-8. The structure of vMIP consists of 71 residues and is a monomer under most conditions. It helps its virus evade the host immune system through selectively blocking and activating different receptors, preferentially...
Investigational
Matched Synonyms: … Viral Macrophage Inflammatory Protein-II …
Matched Name: … Viral Macrophage-Inflammatory Protein …
Matched Description: … Viral macrophage inflammatory protein-II (vMIP) is a highly basic protein and human chemokine analog ... The structure of vMIP consists of 71 residues and is a monomer under most conditions. ... It helps its virus evade the host immune system through selectively blocking and activating different …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins …
Matched Name: … Viral Macrophage-Inflammatory Protein …
Matched Description: … Viral macrophage inflammatory protein-II (vMIP) is a highly basic protein and human chemokine analog ... The structure of vMIP consists of 71 residues and is a monomer under most conditions. ... It helps its virus evade the host immune system through selectively blocking and activating different …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins …
Lanimostim
Investigational
Matched Synonyms: … 4-221-Colony-stimulating factor 1 (human clone p3ACSF-69 reduced) …
Parathyroid hormone
Parathyroid hormone (PTH) is a single-chain polypeptide composed of 84 amino acids. Available as Preotact, it is an identical form of human recombinant hormome which produced as a fusion protein undergoeing post-translational processing involving the cleavage of the OmpA leader sequence, leaving the mature protein as a single-chain 84 amino-acids...
Approved
Investigational
Matched Synonyms: … Parathormone (human recombinant) ... Parathyroid hormone (1-84) human recombinant …
Matched Description: … Food and Drug Administration (FDA). ... The name Preos and the New Drug Application is pending approval by the U.S. ... used in the treatment of osteoporosis in postmenopausal women at high risk of osteoporotic fractures and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Calcium-Regulating Hormones and Agents ... Sex Hormones and Insulins ... Parathyroid Hormones and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Food and Drug Administration (FDA). ... The name Preos and the New Drug Application is pending approval by the U.S. ... used in the treatment of osteoporosis in postmenopausal women at high risk of osteoporotic fractures and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Calcium-Regulating Hormones and Agents ... Sex Hormones and Insulins ... Parathyroid Hormones and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Metoprolol
Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.[A175159, L5530] The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. To this date,...
Approved
Investigational
Matched Description: … Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives ... widely prescribed in the Netherlands, New Zealand, and the US. ... [T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is …
Matched Mixtures name: … Metoprolol Tartrate and Hydrochlorothiazide ... Metoprolol Tartrate and Hydrochlorothiazide ... Metoprolol Tartrate and Hydrochlorothiazide …
Matched Categories: … Beta Blocking Agents and Thiazides ... metoprolol and felodipine ... metoprolol and ivabradine ... metoprolol and amlodipine ... metoprolol and thiazides …
Matched Products: … Q-metoprolol (type L) ... Nu-metoprolol (type L) ... Apo-metoprolol (type L) …
Matched Mixtures name: … Metoprolol Tartrate and Hydrochlorothiazide ... Metoprolol Tartrate and Hydrochlorothiazide ... Metoprolol Tartrate and Hydrochlorothiazide …
Matched Categories: … Beta Blocking Agents and Thiazides ... metoprolol and felodipine ... metoprolol and ivabradine ... metoprolol and amlodipine ... metoprolol and thiazides …
Matched Products: … Q-metoprolol (type L) ... Nu-metoprolol (type L) ... Apo-metoprolol (type L) …
Toralizumab
Toralizumab is under investigation in clinical trial NCT03605927 (CD40-L Blockade for Prevention of Acute Graft-versus-host Disease).
Investigational
Matched Synonyms: … Anti-CD 154 human-mouse monoclonal antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Bersanlimab
Bersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule 1 (ICAM-1).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human intercellular adhesion molecule icam-1) (human monoclonal bi-505 .gamma ... Immunoglobulin g1-lambda, anti-(homo sapiens icam1(intercellular adhesion molecule 1, icam-1, cd54)), human …
Interferon beta-1a
Human interferon beta (166 residues), glycosylated, MW=22.5kD. It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced. The amino acid sequence is identical to that of natural human interferon beta.
Approved
Investigational
Matched Synonyms: … Interferon beta, recombinant human ... Interferon beta-1a (recombinant human) …
Matched Description: … gene has been introduced. ... Human interferon beta (166 residues), glycosylated, MW=22.5kD. ... The amino acid sequence is identical to that of natural human interferon beta. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Interferon Type I ... Recombinant Human Interferon beta ... Antineoplastic and Immunomodulating Agents …
Matched Description: … gene has been introduced. ... Human interferon beta (166 residues), glycosylated, MW=22.5kD. ... The amino acid sequence is identical to that of natural human interferon beta. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Interferon Type I ... Recombinant Human Interferon beta ... Antineoplastic and Immunomodulating Agents …
Avalglucosidase alfa
Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe disease, a rare inherited neuromuscular disorder caused by the deficiency of the alpha-glucosidase (GAA) enzyme. GAA is an essential enzyme that hydrolyzes glycogen into free glucose for use in cellular functions. In Pompe disease, the...
Approved
Investigational
Matched Synonyms: … Neo-recombinant human acid alpha-glucosidase …
Matched Description: … muscle weakness, which leads to premature death and debilitating effects on people’s lives. ... Pompe disease is characterized by progressive muscle weakness and loss of motor function, including respiratory ... muscle weakness, and loss of motor function. …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Description: … muscle weakness, which leads to premature death and debilitating effects on people’s lives. ... Pompe disease is characterized by progressive muscle weakness and loss of motor function, including respiratory ... muscle weakness, and loss of motor function. …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Metamizole
Metamizole (dipyrone) is a pyrazolone derivative that belongs to the group of nonacid nonopioids. It is considered a potent analgesic and antipyretic with favourable gastrointestinal tolerability. Metamizole was formerly marketed in the US as Dimethone tablets and injection, Protemp oral liquid, and other drug products, and was withdrawn due to...
Approved
Investigational
Withdrawn
Matched International brands: … Protemp …
Matched Description: … [A251885] Metamizole was formerly marketed in the US as Dimethone tablets and injection, Protemp oral ... , Norway and Australia. ... liquid, and other drug products, and was withdrawn due to its association with potentially fatal agranulocytosis …
Matched Description: … [A251885] Metamizole was formerly marketed in the US as Dimethone tablets and injection, Protemp oral ... , Norway and Australia. ... liquid, and other drug products, and was withdrawn due to its association with potentially fatal agranulocytosis …
Albumin iodinated I-131 serum
Iodinated I-131 serum albumin is a radiopharmaceutical agent used for several diagnostic purposes, including the determination of body fluid volumes and the imaging of certain tissues.
Approved
Matched Synonyms: … Human albumin I-131 ... Human serum albumin I-131 ... Iodinated (131I) human serum albumin …
Matched Description: … radiopharmaceutical agent used for several diagnostic purposes, including the determination of body fluid volumes and …
Matched Description: … radiopharmaceutical agent used for several diagnostic purposes, including the determination of body fluid volumes and …
Peptide YY (1-36)
Investigational
Matched Synonyms: … Peptide YY human ... Peptide YY (human) ... Peptide YY human (1-36) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Cepeginterferon alfa-2B
Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic Hepatitis C).
Investigational
Matched Synonyms: … Pegylated human interferon A-2B …
Matched Description: … Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Displaying drugs 1051 - 1075 of 1293 in total