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Displaying drugs 10801 - 10825 of 11549 in total
PPI-2458
PPI-2458 represents a potentially new and important addition to the growing list of therapeutics aimed at specific molecular oncology targets. PPI-2458 is a novel, proprietary molecule belonging to the fumagillin class of compounds that specifically targets the MetAP-2 enzyme. This class of compounds has been shown to prevent both abnormal...
Investigational
Matched Iupac: … (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-1-oxaspiro[2.5]octan ... -6-yl N-[(1R)-1-carbamoyl-2-methylpropyl]carbamate …
Squalamine
Investigational
Matched Iupac: … {[(3R,6R)-6-[(1S,2S,5S,7R,9R,10R,11S,14R,15R)-5-({3-[(4-aminobutyl)amino]propyl}amino)-9-hydroxy-2,15 ... -dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]-2-methylheptan-3-yl]oxy}sulfonic acid …
Matched Salts cas: … 320725-47-1 …
Matched Salts cas: … 320725-47-1 …
DiaPep 277
DiaPep 277 is a 24-mer laboratory-made peptide derived from Hsp60(437-460).
Investigational
Matched Iupac: … -2-amino-1-hydroxy-3-methylbutylidene]amino}-1-hydroxy-4-methylpentylidene]amino}-1-hydroxyethylidene ... )methylidene}amino)-1-hydroxypropylidene]amino}-1-hydroxy-4-methylpentylidene]amino}-3-carboxy-1-hydroxypropylidene ... ]amino}-1,3-dihydroxypropylidene]amino}-1-hydroxy-4-methylpentylidene]amino}-3-hydroxybutanoyl]pyrrolidin ... ]amino}-1-hydroxy-4-methylpentylidene]amino}-1-hydroxy-4-methylpentylidene]amino}-5-carbamimidamido-1 ... ]amino}-4-carboxy-1-hydroxybutylidene]amino}butanedioic acid …
Matched Categories: … Diabetes Mellitus, Type 1 …
Matched Categories: … Diabetes Mellitus, Type 1 …
Oleylphosphocholine
Investigational
Matched Synonyms: … Ethanaminium, 2-((hydroxy((9z)-9-octadecen-1-yloxy)phosphinyl)oxy)-n,n,n-trimethyl-, inner salt …
Matched Iupac: … (9Z)-octadec-9-en-1-yl 2-(trimethylazaniumyl)ethyl phosphate …
Matched Iupac: … (9Z)-octadec-9-en-1-yl 2-(trimethylazaniumyl)ethyl phosphate …
Kitasamycin
Kitasamycin is a macrolide antibiotic derived from Streptomyces kitasatoensis.
Experimental
Matched Iupac: … oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy}-4-hydroxy-2,4 ... -dimethyloxan-3-yl 3-methylbutanoate ... 6S)-6-{[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1- …
Matched Salts cas: … 37280-56-1 …
Matched Salts cas: … 37280-56-1 …
Tetragalacturonic acid hydroxymethylester
Experimental
Matched Iupac: … yl]oxy}oxan-3-yl]oxy}-4,5-dihydroxy-2-[(hydroxymethoxy)carbonyl]oxan-3-yl]oxy}-3,4,5-trihydroxyoxane- ... 2-[(hydroxymethoxy)carbonyl]-6-{[(2S,3R,4R,5R,6S)-4,5,6-trihydroxy-2-[(hydroxymethoxy)carbonyl]oxan-3- …
R048-8071
Experimental
Matched Iupac: … {6-[4-(4-bromobenzoyl)-3-fluorophenoxy]hexyl}(methyl)(prop-2-en-1-yl)amine …
Fluoresceinylthioureido
Experimental
Matched Iupac: … 5-[(ethylcarbamothioyl)amino]-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid …
Bromo-Willardiine
Experimental
Matched Iupac: … (2S)-2-amino-3-(5-bromo-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid …
Varespladib methyl
Varespladib methyl has been investigated for the treatment of Acute Coronary Syndrome. Studies showed that Varespladib methyl treatment resulted in significant positive changes on lipoproteins and inflammation.
Investigational
Matched Iupac: … methyl 2-{[1-benzyl-3-(carbamoylcarbonyl)-2-ethyl-1H-indol-4-yl]oxy}acetate …
Haloxyfop-P
Experimental
Matched Iupac: … (2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid …
Opaviraline
Experimental
Matched Iupac: … propan-2-yl (2S)-2-ethyl-7-fluoro-3-oxo-1,2,3,4-tetrahydroquinoxaline-1-carboxylate …
Zofenoprilat
Experimental
Matched Iupac: … (2S,4S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]-4-(phenylsulfanyl)pyrrolidine-2-carboxylic acid …
Metiamide
Metiamide is an H-2 receptor antagonist derived from burimamide. It was an intermediate product on the path to developing cimetidine.
Experimental
Matched Iupac: … 3-methyl-1-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)thiourea …
Dutogliptin
Dutogliptin has been investigated for the treatment of Diabetes Mellitus, Type II.
Investigational
Matched Iupac: … [(2R)-1-(2-{[(3R)-pyrrolidin-3-yl]amino}acetyl)pyrrolidin-2-yl]boronic acid …
Varespladib
Varespladib has been investigated for the treatment and prevention of Sickle Cell Disease, Vaso-occlusive Crisis, and Acute Coronary Syndrome.
Investigational
Matched Iupac: … 2-{[1-benzyl-3-(carbamoylcarbonyl)-2-ethyl-1H-indol-4-yl]oxy}acetic acid …
QGC-001
QGC001 has been used in trials studying the treatment of Essential Hypertension.
Investigational
Matched Iupac: … (3S)-3-amino-4-{[(2S)-2-amino-4-sulfobutyl]disulfanyl}butane-1-sulfonic acid …
Propenidazole
Experimental
Matched Iupac: … ethyl (2E)-2-[(1-methyl-5-nitro-1H-imidazol-2-yl)methylidene]-3-oxobutanoate …
Niaprazine
Niaprazine is a selective brain catecholamine depletor.
Experimental
Matched Iupac: … N-{4-[4-(4-fluorophenyl)piperazin-1-yl]butan-2-yl}pyridine-3-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Dienestrol diacetate
Experimental
Matched Iupac: … 4-[(2E,4E)-4-[4-(acetyloxy)phenyl]hexa-2,4-dien-3-yl]phenyl acetate …
Triazavirin
Triazavirin is a guanine nucleotide analog antiviral originally developed in Russia that has shown efficacy against influenza A and B, including the H5N1 strain.[A191709,A191625,A191916] It appears that Triazavirin has shown promise in reducing influenza disease severity and associated complications. Given the similarities between SARS-CoV-2 and H5N1, health officials are investigating...
Experimental
Matched Iupac: … 7-(methylsulfanyl)-3-nitro-1H,4H-[1,2,4]triazolo[3,2-c][1,2,4]triazin-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Orelabrutinib
Orelabrutinib is under investigation in clinical trial NCT04305197 (A Study of ICP-022 in Patients With Systemic Lupus Erythematosus (SLE)).
Investigational
Matched Iupac: … 2-(4-phenoxyphenyl)-6-[1-(prop-2-enoyl)piperidin-4-yl]pyridine-3-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Tebipenem pivoxil
Investigational
Matched Iupac: … [(4R,5S,6S)-3-{[1-(4,5-dihydro-1,3-thiazol-2-yl)azetidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl ... -7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carbonyloxy]methyl 2,2-dimethylpropanoate …
Bacteriochlorophyll A
A specific bacteriochlorophyll that is similar in structure to CHLOROPHYLL A.
Experimental
Matched Iupac: … magnesium(2+) (3R,11R,12R,21S,22S)-16-acetyl-11-ethyl-3-(methoxycarbonyl)-12,17,21,26-tetramethyl-4-oxo ... -22-(3-oxo-3-{[(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-yl]oxy}propyl)-7,23,24,25-tetraazahexacyclo ... [18.2.1.1^{5,8}.1^{10,13}.1^{15,18}.0^{2,6}]hexacosa-1(23),2(6),5(26),8,10(25),13,15,17,19-nonaene-7,24 …
Chlorophyll B
A light, silvery, metallic element. It has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. Its salts are essential in nutrition, being required for the activity of many enzymes, especially those concerned with oxidative phosphorylation. It is a component of both intra- and extracellular fluids and is...
Experimental
Matched Iupac: … magnesium(2+) (3R,21S,22S)-16-ethenyl-11-ethyl-12-formyl-3-(methoxycarbonyl)-17,21,26-trimethyl-4-oxo ... -22-(3-oxo-3-{[(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-yl]oxy}propyl)-7,23,24,25-tetraazahexacyclo ... [18.2.1.1^{5,8}.1^{10,13}.1^{15,18}.0^{2,6}]hexacosa-1(23),2(6),5(26),8,10(25),11,13,15,17,19-decaene …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds with 4 or More Rings …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds with 4 or More Rings …
Displaying drugs 10801 - 10825 of 11549 in total