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Displaying drugs 1076 - 1100 of 2328 in total
Lacosamide is an antiepileptic drug used to treat seizures. As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium currents. Lacosamide exhibits a stereoselective mode of interaction with sodium channels. Lacosamide was first approved by the European Commission in August 2008 and was later...
Approved
Quizartinib is an oral and potent fms-like tyrosine kinase 3 (FLT3) inhibitor and it is the first drug developed specifically targeting FLT3, as other agents with FLT3 inhibition activities were investigated with other targets in mind. Additionally, quizartinib also demonstrates inhibitory activity toward FLT3 with internal tandem duplication (ITD), although...
Approved
Investigational
Approved
Experimental
Matched Mixtures name: … SMOOTH GATOR 60-second Pain Relief …
Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.
Approved
Investigational
Matched Mixtures name: … Safeton Sting Relief Pad 60 Isopropyl Alcohol 6 Benzocaine …
Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine kinase inhibitor indicated for chronic myelogenous leukemia (CML), specifically Philadelphia chromosome-positive (Ph+) CML. Philadelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein.[A6902,A261796,A261801] The first BCR-ABL inhibitor,...
Approved
Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. The compound was first extracted and isolated from plant species Gaultheria procumbens in 1843. It can be manufactured synthetically and it used as a fragrance, in foods, beverages, and...
Approved
Vet approved
Matched Mixtures name: … LINIMENTO VENECIANO NÂș 9
A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
Approved
Investigational
Vet approved
Matched Salts cas: … 578-36-9
Matched Products: … Neutrogena SkinClearing Oil Free Makeup - Natural Beige 60 ... CLEAR AND COVER ACNE TREATMENT CONCEALER CLEAR AND COVER ACNE TREATMENT CONCEALER 9 almond …
Irbesartan is an angiotensin receptor blocker (ARB) indicated to treat hypertension or diabetic nephropathy.[L7456,L7459] It can also be used as part of a combination product with hydrochlorothiazide for patients not well controlled or not expected to be well controlled on monotherapy. Unlike angiotensin converting enzyme inhibitors, ARBs are not associated...
Approved
Investigational
A compound produced from succinyl-CoA and glycine as an intermediate in heme synthesis. It is used as a photochemotherapy for actinic keratosis. [PubChem]
Approved
Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication . In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local...
Approved
Vet approved
Matched Salts cas: … 73-78-9
Matched Mixtures name: … Acunistat-60
Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. Although similar in structure to other opioids, it has minimal interaction with opioid receptors. Dextromethorphan was granted FDA approval before 3 December 1957.[A215412,L14997]
Approved
Matched Salts cas: … 125-69-9
Matched Mixtures name: … VICKS VAPODRY SURUP, 60 ML …
Experimental
Matched International brands: … Tween 60
Matched Synonyms: … Polisorbato 60 ... Polysorbata 60 ... Polysorbate 60
Matched Name: … Polysorbate 60
Investigational
Matched Name: … HER-902
Experimental
Matched Synonyms: … 9-phenanthrenamine ... 9-phenanthrylamine ... phenanthren-9-amine …
Matched Name: … 9-Aminophenanthrene …
Matched Iupac: … phenanthren-9-amine …
Cobalt Co-60 is under investigation in clinical trial NCT02891083 (Adjuvant Therapies or Surgery Alone for High Risk pN0 Esophageal Cancer).
Investigational
Matched Name: … Cobalt Co-60
Matched Description: … Cobalt Co-60 is under investigation in clinical trial NCT02891083 (Adjuvant Therapies or Surgery Alone …
Investigational
Matched Synonyms: … 3,4,5-piperidinetriol, 2-(hydroxymethyl)-1-(9-methoxynonyl)-, (2r,3r,4r,5s)- …
Matched Name: … N-9-Methoxynonyldeoxynojirimycin …
Matched Iupac: … (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(9-methoxynonyl)piperidine-3,4,5-triol …
Matched Salts name: … N-9-Methoxynonyldeoxynojirimycin hydrochloride …
Experimental
Matched Synonyms: … (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid …
Matched Name: … 9(S)-HODE …
Matched Iupac: … (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid …
Experimental
Matched Name: … 9-Deazaguanine …
Experimental
Matched Synonyms: … 9-Hydroxypropyladenine, S-Isomer …
Matched Name: … S-9-(2-hydroxypropyl)adenine …
Matched Iupac: … (2S)-1-(6-amino-9H-purin-9-yl)propan-2-ol …
Experimental
Matched Synonyms: … 9-Hydroxypropyladenine, R-Isomer …
Matched Name: … R-9-(2-hydroxypropyl)adenine …
Matched Iupac: … (2R)-1-(6-amino-9H-purin-9-yl)propan-2-ol …
Pivaloyloxymethyl butyrate (AN-9), an acyloxyalkyl ester prodrug of butyric acid (BA), exhibited low toxicity and significant anticancer activity in vitro and in vivo. It shows greater potency than BA at inducing malignant cell differentiation and tumor growth inhibition and has demonstrated more favorable toxicological, pharmacological, and pharmaceutical properties than BA...
Investigational
Matched Name: … AN-9
Matched Description: … Pivaloyloxymethyl butyrate (AN-9), an acyloxyalkyl ester prodrug of butyric acid (BA), exhibited low …
Investigational
Matched Name: … AKV-9
Experimental
Matched Name: … 9-Methylguanine …
Matched Iupac: … 2-amino-9-methyl-6,9-dihydro-1H-purin-6-one …
Experimental
Matched Name: … 9-deazainosine …
Experimental
Matched Name: … 9-Deazahypoxanthine …
Displaying drugs 1076 - 1100 of 2328 in total