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Displaying drugs 1076 - 1100 of 1340 in total
Magnesium silicate is a compound of magnesium oxide and silicon. It is the magnesium salt of silicic acid containing an unspecified amount of water. The molecular formula can be expressed more clearly as MgSiO3.xH2O. It is known as talc and it presents many uses in the cosmetic industry, food industry...
Approved
Matched Name: … Magnesium silicate …
Matched Iupac: … silicon(4+) ion magnesium(2+) ion trioxidandiide …
Matched Description: … Magnesium silicate is a compound of magnesium oxide and silicon. ... It is the magnesium salt of silicic acid containing an unspecified amount of water. ... [T186] It is known as talc and it presents many uses in the cosmetic industry, food industry and pharmaceutical …
Matched Categories: … Aluminum and magnesium containing antacids ... Alimentary Tract and Metabolism ... Silicon Compounds ... Magnesium Compounds ... magnesium silicate …
Approved
Experimental
Matched Name: … Magnesium malate …
Matched Iupac: … magnesium(2+) 2-hydroxybutanedioate …
Investigational
Matched Synonyms: … Human recombinant histidyl-t-RNA synthetase (residues 2-506) …
Amprenavir is a protease inhibitor used to treat HIV infection.
Approved
Investigational
Matched Synonyms: … furanyl ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)carbamate
Matched Iupac: … oxolan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-aminobenzenesulfonamido]-1-phenylbutan-2-yl]carbamate
Matched Categories: … Amprenavir and Prodrugs …
Oxibendazole is a polymerase inhibitor in phase III trials for the treatment of helminth intestinal infections.
Investigational
Vet approved
Matched Synonyms: … Methyl 5-n-propoxy-2-benzimidazole carbamate
Matched Iupac: … methyl N-(6-propoxy-1H-1,3-benzodiazol-2-yl)carbamate
Investigational
Matched Synonyms: … VEGFR-2 DNA vaccine VXM01 …
Experimental
Matched Synonyms: … Silica, hydrophobic colloidal …
Matched Name: … Silica dimethyl silylate …
Almasilate is a buffering antacid that has been used in peptic ulcers and dyspepsia. It is a crystalline polyhydrate of aluminium/magnesium silicate and mediates its buffering activity by binding hydrogen ions within the polymer. However its therapeutic efficacy is not comparable to other approved antacids, as it is no more...
Approved
Experimental
Matched Synonyms: … Magnesium aluminosilicate hydrate …
Matched Iupac: … dialuminium(3+) ion magnesium(2+) ion hydrate disilicate …
Matched Description: … It is a crystalline polyhydrate of aluminium/magnesium silicate and mediates its buffering activity by ... Almasilate is a buffering antacid that has been used in peptic ulcers and dyspepsia. ... efficacy is not comparable to other approved antacids, as it is no more effective in neutralizing acid and
Matched Categories: … Aluminum and magnesium containing antacids ... Alimentary Tract and Metabolism ... Silicon Compounds …
Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker, and the R(+) enantiomer is an alpha-1 adrenoceptor blocker.[L7889,L7892] It is currently used to treat heart failure, left ventricular dysfunction, and hypertension.[L7889,L7892] The dual action of carvedilol is advantageous in combination therapies as...
Approved
Investigational
Matched Description: … , and the R(+) enantiomer is an alpha-1 adrenoceptor blocker. ... Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker ... [L7889,L7892] It is currently used to treat heart failure, left ventricular dysfunction, and hypertension …
Matched Salts name: … Carvedilol phosphate
Matched Categories: … Calcium-Regulating Hormones and Agents ... Alpha and Beta Blocking Agents ... carvedilol and ivabradine ... Calcium Channel Blockers …
Matched Products: … Carvedilol Phosphate
Dolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). The effect of this drug has no homology in human host cells, which gives it excellent tolerability and minimal toxicity. Dolutegravir was developed by ViiV Healthcare...
Approved
Matched Description: … The effect of this drug has no homology in human host cells, which gives it excellent tolerability and ... [A31342] Dolutegravir was developed by ViiV Healthcare and FDA-approved on August 12, 2013. …
Matched Salts name: … Dolutegravir sodium
Matched Categories: … lamivudine and dolutegravir ... dolutegravir and rilpivirine ... lamivudine, abacavir and dolutegravir ... lamivudine, tenofovir disoproxil and dolutegravir …
Matched Products: … DOLUTEGRAVIR SODIUM
MK-4541 is a 4-azasteroid and a selective androgen receptor modulator (SARM). MK-4541 acts as a dual selective SARM and is both a potent androgen receptor antagonist and a 5α-reductase inhibitor.
Investigational
Matched Synonyms: … 9bS,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,9b,10,11-decahydro-1H-indeno[5,4-f]quinolin-1-yl]carbamate
Matched Description: … MK-4541 acts as a dual selective SARM and is both a potent androgen receptor antagonist and a 5α-reductase ... MK-4541 is a 4-azasteroid and a selective androgen receptor modulator (SARM). …
INO-4800 is a DNA vaccine containing the full sequence for the SARS-CoV-2 Spike (S) protein in development for immunization against COVID-19. Early in vitro studies using HEK-293T cells demonstrated that the transfection of INO-4800 results in the expression of S protein by human cells.[A214475, A214478] Follow up studies in both...
Investigational
Matched Synonyms: … INO-4800 DNA Coronavirus Vaccine …
Matched Description: … [A214475, A214478] Follow up studies in both BALB/c mice and Hartley guinea pigs demonstrated the ability ... of INO-4800 to induce both humoral and T cell-mediated immunity against SARS-CoV-2, including in the ... clinical trial through South Korea's Seoul National University Hospital was announced on June 4, 2020, and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to...
Approved
Investigational
Matched Description: … [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic ... [L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002. …
Matched Salts name: … Ertapenem sodium
Matched Products: … Ertapenem Sodium
Experimental
Matched Name: … Sulfur dioxide
Investigational
Matched Name: … Cerium dioxide
Experimental
Matched Name: … (1Z)-2-HYDROXY-3-OXOHEX-1-EN-1-YL DIHYDROGEN PHOSPHATE
Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Matched Description: … is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and
Matched Salts name: … Alendronate calcium ... Alendronate sodium ... Alendronate sodium anhydrous …
Matched Categories: … alendronic acid, calcium and colecalciferol, sequential ... Drugs Affecting Bone Structure and Mineralization ... alendronic acid and colecalciferol ... alendronic acid and alfacalcidol, sequential …
Matched Products: … Alendronate Sodium ... Ag-alendronate Sodium ... Jamp Alendronate Sodium
TTX-siPDL1 is an siRNA-based modulator of programmed death-ligand 1.
Investigational
Matched Synonyms: … Magnetic nanocarrier-conjugated small interfering RNA against programmed death ligand 1 …
Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear. As of January 29 2018, CutisPharma's Firvanq is the only FDA approved vancomycin oral liquid treatment option available for the the treatment of...
Approved
Matched Description: … kidneys and the inner ear. ... It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to ... liquid treatment option available for the the treatment of _Clostridium difficile_ associated diarrhea and
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Products: … Vancomycin Injection USP In 0.9% Sodium Chloride
Experimental
Matched Name: … 4-Carbamoyl-1-Beta-D-Ribofuranosyl-Imidazolium-5-Olate-5'-Phosphate
Experimental
Matched Name: … 2'-O-Methyl-3'-Methyl-3'-Deoxy-Arabinofuranosyl-Thymine-5'-Phosphate
Experimental
Matched Name: … 4-(6-CHLORO-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL) BUTYL PHOSPHATE
Quaratusugene ozeplasmid is under investigation in clinical trial NCT05062980 (Quaratusugene Ozeplasmid (Reqorsa) in Combination With Pembrolizumab in Previously Treated Non-small Lung Cancer).
Investigational
Matched Synonyms: … Dna (synthetic plasmid vector plj143/kgb2/tusc2) ... Dna-lipid complex (dotap/cholesterol) plasmid vector (plj143/pkgb2/tusc2, baylor) expressing the tusc2 …
Investigational
Matched Synonyms: … Cotsiranib tgf-.beta.1 si-rna free acid component ... Rna, (a-g-a-a-g-u-u-g-g-c-a-u-g-g-u-a-g-c-c-c-u-u-g-g-g), complex with rna (c-c-c-a-a-g-g-g-c-u-a-c-c-a-u-g-c-c-a-a-c-u-u-c-u ... Stp-705 component tgf-.beta.1 si-rna free acid …
Matched Salts name: … Pixofisiran sodium
Experimental
Matched Name: … 1-(PHENYLMETHYL)CYCLOPENTYL[(1S)-1-FORMYLPENTYL]CARBAMATE
Matched Iupac: … 1-benzylcyclopentyl N-[(2S)-1-oxohexan-2-yl]carbamate
Displaying drugs 1076 - 1100 of 1340 in total