Displaying drugs 11001 - 11025 of 11900 in total
OAV201
OAV201 is a non-replicating, recombinant adeno-associated virus serotype 9 (AAV9) containing the human Methyl CpG Binding Protein 2B (MECP2B) cDNA under the control of a segment of the murine MECP2 promoter. It was first developed by Novartis and investigated for the treatment of Rett syndrome, but further investigation in clinical...
Investigational
Matched Description: … OAV201 is a non-replicating, recombinant adeno-associated virus serotype 9 (AAV9) containing the human ... Methyl CpG Binding Protein 2B (MECP2B) cDNA under the control of a segment of the murine MECP2 promoter …
Dendritic cells vaccine
The recombinant chimeric DC vaccine is a subunit-based vaccine candidate investigated for safety and effectiveness against SARS-CoV-2-induced pneumonia. With a better safety profile than inactivated and live-attenuated virus and virus-vector vaccines, the recombinant chimeric DC vaccine reduces the risk of virulence recovery, pre-existing anti-vector immunity, and incomplete viral inactivation.
As...
Investigational
Matched Description: … The recombinant chimeric DC vaccine is a subunit-based vaccine candidate investigated for safety and ... With a better safety profile than inactivated and live-attenuated virus and virus-vector vaccines, the …
Rupintrivir
Rupintrivir is a rhinovirus 3C protease inhibitor in development for use against human rhinoviral (HRV) infections. Rupintrivir was active against all 48 HRV serotypes tested in a cell protection assay in H1-HeLa cells. It is designed to combat colds caused by rhinovirus.
Investigational
Matched Description: … Rupintrivir is a rhinovirus 3C protease inhibitor in development for use against human rhinoviral (HRV ... Rupintrivir was active against all 48 HRV serotypes tested in a cell protection assay in H1-HeLa cells …
INGN 225
INGN 225 is a therapeutic consisting of a cancer patient's own immune cells treated with an adenovector carrying the human p53 gene, Ad-p53. INGN 225 is currently in Phase 1/2 trials in patients with small cell lung cancer and breast cancer.
Investigational
Matched Description: … INGN 225 is a therapeutic consisting of a cancer patient's own immune cells treated with an adenovector …
(4R)-limonene
Limonene is common in cosmetic products. As the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a flavoring to mask the bitter taste of alkaloids, and as a fragrant in perfumery.
Investigational
Matched Description: … flavoring to mask the bitter taste of alkaloids, and as a fragrant in perfumery. ... citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a …
Technetium Tc-99m ciprofloxacin
99mTc-Ciprofloxacin is a new formulation of ciprofloxacin (INFECTON), being investigated as a radioimaging agent for the potential diagnosis of infection, including fever of unknown origin, osteomyelitis, wound infection, abdominal abscess, pneumonia, appendicitis and tuberculosis. INFECTON combines the widely used antibiotic, ciprofloxacin, with Technetium ((99m)Tc), the most commonly used radioisotope in...
Investigational
Matched Description: … 99mTc-Ciprofloxacin is a new formulation of ciprofloxacin (INFECTON), being investigated as a radioimaging …
KIN-3248
KIN-3248 is a small molecule that targets and inhibits oncogenic fibroblast growth factor receptors (FGFRs). It was designed to mainly target FGFR2 and FGFR3 alterations, which act as oncogenic drivers in 10-20% of cholangiocarcinoma and 20-35% of urothelial cancers, respectively. While effective, disease progression may occur 6 to 8 months...
Investigational
Matched Description: … KIN-3248 is a small molecule that targets and inhibits oncogenic fibroblast growth factor receptors ( …
MDX-018
MDX-018, also known as HuMax-Inflam, is a fully human antibody that is directed to IL-8 (interleukin-8) and may have potential application in oncology and inflammation. Trials will initially focus on studies to treat glioblastoma, a cancer of the central nervous system. Other possible indications include chronic obstructive pulmonary disease (COPD)...
Investigational
Matched Description: … MDX-018, also known as HuMax-Inflam, is a fully human antibody that is directed to IL-8 (interleukin- ... Trials will initially focus on studies to treat glioblastoma, a cancer of the central nervous system. ... HuMax-Inflam was also effective in reducing disease activity in palmoplantar pustulosis patients in a …
D-Phenylalanine
An essential aromatic amino acid that is a precursor of melanin; dopamine; noradrenalin (norepinephrine), and thyroxine. [PubChem]
Experimental
Matched Description: … An essential aromatic amino acid that is a precursor of melanin; dopamine; noradrenalin (norepinephrine …
Uridine 5'-triphosphate
Uridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety.
Experimental
Investigational
Matched Description: … A uracil nucleotide containing three phosphate groups esterified to the sugar moiety. …
Tiamulin
Tiamulin is a pleuromutilin antibiotic drug that is used in veterinary medicine particularly for pigs and poultry.
Vet approved
Matched Description: … Tiamulin is a pleuromutilin antibiotic drug that is used in veterinary medicine particularly for pigs …
Lanabecestat
Lanabecestat is under investigation in clinical trial NCT03499041 (A Study of LY3314814 in Participants With Liver Impairment).
Investigational
Matched Description: … Lanabecestat is under investigation in clinical trial NCT03499041 (A Study of LY3314814 in Participants …
SB-1578
SB-1578 is under investigation in clinical trial NCT01235871 (A Single and Multiple-Dose Study of SB1578).
Investigational
Matched Description: … SB-1578 is under investigation in clinical trial NCT01235871 (A Single and Multiple-Dose Study of SB1578 …
Zansecimab
Zansecimab is under investigation in clinical trial NCT04342897 (A Study of LY3127804 in Participants With COVID-19).
Investigational
Matched Description: … Zansecimab is under investigation in clinical trial NCT04342897 (A Study of LY3127804 in Participants …
KB109
KB109 is a prebiotic to feed healthy bacteria for them to to outcompete multi-drug resistance organisms.
Investigational
Matched Description: … KB109 is a prebiotic to feed healthy bacteria for them to to outcompete multi-drug resistance organisms …
SKF-96365 free base
SKF-96365 is a receptor-mediated calcium entry (RMCE) inhibitor structurally different from other calcium antagonists.
Investigational
Matched Description: … SKF-96365 is a receptor-mediated calcium entry (RMCE) inhibitor structurally different from other calcium …
MK-4830
MK-4830 is a monoclonal antibody that targets the myeloid-specific immunoglobulin-like transcript (ILT) 4 receptor.
Investigational
Matched Description: … MK-4830 is a monoclonal antibody that targets the myeloid-specific immunoglobulin-like transcript (ILT …
ETBX-011
ETBX-011 is a cancer vaccine used to treat patients with cancers that express carcinoembryonic antigen (CEA).
Investigational
Matched Description: … ETBX-011 is a cancer vaccine used to treat patients with cancers that express carcinoembryonic antigen …
RTL-1000
RTL-1000 is a recombinant T-Cell receptor ligand being investigated for the treatment of multiple sclerosis.
Investigational
Matched Description: … RTL-1000 is a recombinant T-Cell receptor ligand being investigated for the treatment of multiple sclerosis …
TLY-012
TLY-012 is a PEGylated recombinant human tumor necrosis factor-related apoptosis-inducing ligand (PEGylated TRAIL).
Investigational
Matched Description: … TLY-012 is a PEGylated recombinant human tumor necrosis factor-related apoptosis-inducing ligand (PEGylated …
IDUA-RTB
RTB-IDUA is a fusion protein of alpha-L-iduronidase (IDUA) and ricin transport subunit B (RTB).
Investigational
Matched Description: … RTB-IDUA is a fusion protein of alpha-L-iduronidase (IDUA) and ricin transport subunit B (RTB). …
Calpurbatug
Calpurbatug (TRL1068) is a high-affinity and broad-spectrum human antibody that targets and disintegrates bacterial biofilm.
Investigational
Matched Description: … Calpurbatug (TRL1068) is a high-affinity and broad-spectrum human antibody that targets and disintegrates …
Surotomycin
Surotomycin has been used in trials studying the treatment of Diarrhea and Clostridium Difficile Infection. It is a benzenebutanoic acid derivative patented by Cubist Pharmaceuticals, Inc. as antibacterial agents for the treatment of Gram-positive infections. Surotomycin has a fourfold greater in vitro potency than vancomycin against C. Difficile and other...
Investigational
Matched Description: … Surotomycin has a fourfold greater in vitro potency than vancomycin against C. ... It is a benzenebutanoic acid derivative patented by Cubist Pharmaceuticals, Inc. as antibacterial agents ... effective against both initial and relapsing hamster Clostridium difficile-associated diarrhea, with a …
Displaying drugs 11001 - 11025 of 11900 in total