Displaying drugs 11126 - 11150 of 11637 in total
IR501
IR501 (Ravax) is a potential first-in-class vaccine for the treatment of Rheumatoid Arthritis. It specifically targets autoreactive T-cells, reducing their activity. It was last known to be in phase III clinical trials.
Investigational
Matched Description: … IR501 (Ravax) is a potential first-in-class vaccine for the treatment of Rheumatoid Arthritis. …
Ravagalimab
Ravagalimab is under investigation in clinical trial NCT03695185 (A Study to Investigate How Well Ravagalimab (ABBV-323) Works and How Safe It Is in Participants With Moderate to Severe Ulcerative Colitis Who Failed Prior Therapy).
Investigational
Matched Description: … Ravagalimab is under investigation in clinical trial NCT03695185 (A Study to Investigate How Well Ravagalimab …
Tulisokibart
PRA023 is a humanized monoclonal antibody directed to vascular endothelial growth inhibitor, also known as tumour necrosis factor (TNF)-like ligand 1A (TL1A) and TNF superfamily member 15. It is being investigated for ulcerative colitis.
Investigational
Matched Description: … PRA023 is a humanized monoclonal antibody directed to vascular endothelial growth inhibitor, also known …
Vepdegestrant
Vepdegestrant is under investigation in clinical trial NCT05909397 (A Study of ARV-471 (PF-07850327) Plus Palbociclib Versus Letrozole Plus Palbociclib in Participants With Estrogen Receptor Positive, Human Epidermal Growth Factor Negative Advanced Breast Cancer).
Investigational
Matched Description: … Vepdegestrant is under investigation in clinical trial NCT05909397 (A Study of ARV-471 (PF-07850327) …
Ciliary neurotrophic factor
NT-501 is an intraocular implant that contains human cells that have been genetically modified to secrete ciliary neurotrophic factor (CNTF). It is under investigation for the treatment of retinitis pigmentosa and age-related macular degeneration.
Investigational
Edotreotide yttrium Y-90
Investigational
Bavdegalutamide
Bavdegalutamide is under investigation in clinical trial NCT03888612 (Trial of ARV-110 in Patients With Metastatic Castration Resistant Prostate Cancer).
Investigational
Tetraethylammonium
Tetraethylammonium is an experimental drug with no approved indication or marketed formulation. The only marketed drug containing tetraethylammonium was a combination drug called Fosglutamina B6, but this drug has now been discontinued. As an experimental agent, tetraethylammonium is used in its salt forms such as tetraethylammonium chloride and tetraethylammonium bromide....
Experimental
Investigational
Matched Description: … The only marketed drug containing tetraethylammonium was a combination drug called Fosglutamina B6, but ... The most common use of tetraethylammonium presently is as a pharmacological research agent that blocks ... Because of its inhibitory actions at the autonomic ganglia, tetraethylammonium was thought to be a potential …
Befunolol
Befunolol is a beta blocker introduced in 1983 by Kakenyaku Kakko. It is currently in experimental status, and is being tested for the management of open angle glaucoma.
Experimental
Matched Description: … Befunolol is a beta blocker introduced in 1983 by Kakenyaku Kakko. …
Tandamine
Tandamine was researched in 1970s as an antidepressant but was never commercialized. Tandamine is an analog of pirandamine and it acts as a selective serotonin reuptake inhibitor (SSRI).
Experimental
Matched Description: … Tandamine is an analog of pirandamine and it acts as a selective serotonin reuptake inhibitor (SSRI). …
HX-1171
Hx 1171 is under investigation in clinical trial NCT01548391 (A Phase I Clinical Study Study of the Safety, Tolerability, and Pharmacokinetics of HX-1171 in Healthy Male Subjects).
Investigational
Matched Description: … Hx 1171 is under investigation in clinical trial NCT01548391 (A Phase I Clinical Study Study of the Safety …
PF-05089771
PF-05089771 is under investigation in clinical trial NCT01529671 (A Safety And Tolerability Study Of PF-05089771 In Healthy Subjects And In Subjects With Otseoarthritis Of The Knee).
Investigational
Matched Description: … PF-05089771 is under investigation in clinical trial NCT01529671 (A Safety And Tolerability Study Of …
Tavapadon
Tavapadon is under investigation in clinical trial NCT02262767 (A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of PF-06649751 Co-administered With Trimethobenzamide Hydrochloride in Healthy Subjects).
Investigational
Matched Description: … Tavapadon is under investigation in clinical trial NCT02262767 (A Study to Investigate the Safety, Tolerability …
PCS-499
PCS-499 is under investigation in clinical trial NCT01487109 (A Phase 2 Study to Evaluate the Safety and Efficacy of CTP-499 in Type 2 Diabetic Nephropathy Patients).
Investigational
Matched Description: … PCS-499 is under investigation in clinical trial NCT01487109 (A Phase 2 Study to Evaluate the Safety …
Human Lactoferrin Peptide hLF1-11
Human Lactoferrin Peptide hLF1-11 is under investigation in clinical trial NCT00509834 (A Study on the Tolerability and Early Efficacy of Hlf1-11 in Patients With Proven Candidaemia).
Investigational
Matched Description: … Human Lactoferrin Peptide hLF1-11 is under investigation in clinical trial NCT00509834 (A Study on the …
Zampilimab
Zampilimab is under investigation in clinical trial NCT04335578 (A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of UCB7858 in Adult Kidney Transplant Recipients With Chronic Allograft Injury).
Investigational
Matched Description: … Zampilimab is under investigation in clinical trial NCT04335578 (A Study to Evaluate Safety, Tolerability …
Utidelone
Utidelone (UTD1), a novel microtubule stabilizing agent, is an epothilone B analogue produced by genetic engineering.[A257544,A257549] It is under investigation in clinical trials for various cancers.
Investigational
Matched Description: … Utidelone (UTD1), a novel microtubule stabilizing agent, is an epothilone B analogue produced by genetic …
Bacteroides thetaiotaomicron
Bacteroides thetaiotaomicron is a live biotherapeutic. Developed by 4D Pharma, Thetanix, an oral formulation comprising lyophilized Bacteroides thetaiotaomicron, is being investigated for the treatment of Crohn’s disease.
Investigational
Matched Description: … Bacteroides thetaiotaomicron is a live biotherapeutic. …
Foretinib
Foretinib has been used in trials studying the treatment of Cancer, Breast Cancer, Carcinoma, Renal Cell, Recurrent Breast Cancer, and Neoplasms, Head and Neck, among others. Foretinib is an orally available small molecule compound designed to target multiple RTKs implicated in the development, progression and spread of cancer. It inhibits...
Investigational
KD3010
KD3010 is a small molecule peroxisome proliferator-activator receptor delta (PPAR Delta) agonist for the treatment of metabolic disorders, including obesity.
Investigational
Matched Description: … KD3010 is a small molecule peroxisome proliferator-activator receptor delta (PPAR Delta) agonist for …
Solabegron
Solabegron (GW-427,353) is a selective β3 adrenoceptor agonist being developed for the treatment of overactive bladder and irritable bowel syndrome.
Investigational
Matched Description: … Solabegron (GW-427,353) is a selective β3 adrenoceptor agonist being developed for the treatment of overactive …
CHIR-124
CHIR-124 is a potent inhibitor of Chk1 that potentiates the cytotoxicity of topoisomerase I poisons in vitro and in vivo.
Experimental
Matched Description: … CHIR-124 is a potent inhibitor of Chk1 that potentiates the cytotoxicity of topoisomerase I poisons in …
Delpazolid
Delpazolid (LCB01-0371) is under investigation in clinical trial NCT01554995 (A Clinical Study, Randomized, Double-blind, Placebo-controlled, Single Dose Study).
Investigational
Matched Description: … Delpazolid (LCB01-0371) is under investigation in clinical trial NCT01554995 (A Clinical Study, Randomized …
Tiazofurine
Tiazofurine has potential clinical use in cancer treatment as it is a potential inhibitor of Inosine- 5’-monophosphate (IMP) dehydrogenase .
Experimental
Matched Description: … Tiazofurine has potential clinical use in cancer treatment as it is a potential inhibitor of Inosine- …
Stypocaulon scoparium
Stypocaulon scoparium is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Stypocaulon scoparium is a plant/plant extract used in some OTC (over-the-counter) products. …
Displaying drugs 11126 - 11150 of 11637 in total