Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Displaying drugs 1126 - 1150 of 1322 in total

Dasatinib

Dasatinib is an orally available multikinase inhibitor indicated for the treatment of Philadelphia chromosome (Ph)-positive leukemias.[A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region (BCR) gene transcribe the chimeric protein...
Approved
Investigational
Matched Description: … pathogenesis of CML and 15-30% of ALL cases. ... A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and ... acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region (BCR …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … DASİKAM 20 MG FİLM KAPLI TABLET ... DASİKAM 50 MG FİLM KAPLI TABLET ... DASİKAM 70 MG FİLM KAPLI TABLET …

Diosmin

Chronic venous insufficiency is a common condition the western population. Compression and pharmacotherapy are frequently used to manage chronic venous insufficiency, improving circulation and symptoms of venous disease. Diosmin is a bioflavonoid isolated from various plants or synthesized from hesperidin. It is used for the improvement of capillary fragility or...
Approved
Investigational
Matched Description: … circulation and symptoms of venous disease. ... Compression and pharmacotherapy are frequently used to manage chronic venous insufficiency, improving ... improvement of capillary fragility or venous insufficiency, including chronic venous insufficiency (CVI) and …
Matched Mixtures name: … VENAFIX (Diosmin and Hesperidin Tablet) ... Davmorid Film Coated Tablet ... DIOSPER FILM COATED TABLET …
Matched Products: … DAFLON FILM-COATED TABLET 1000 mg ... RUVENTIN FILM COATED TABLET 500MG ... DAFLON 500 MG FILM TABLET, 60 ADET …

Ivabradine

Ivabradine is a novel heart rate lowering medicine for the symptomatic management of stable angina pectoralis and symptomatic chronic heart failure. Ivabradine, brand name Corlanor, was approved by the FDA in April 2015 for the treatment of chronic heart failure in patients with an ejection fraction of ≤35%, in sinus...
Approved
Matched Description: … Although non-dihydropyridine calcium channel blockers and beta blockers also effectively lower heart ... is a novel heart rate lowering medicine for the symptomatic management of stable angina pectoralis and ... pacemaker current (If) in the sinoatrial node in a dose-dependent fashion, resulting in a lower heart rate and …
Matched Mixtures name: … IMPLICOR 50MG/5MG FILM-COATED TABLETS ... IMPLICOR 25MG/5MG FILM-COATED TABLETS ... IMPLICOR 25MG/7.5MG FILM-COATED TABLETS …
Matched Categories: … metoprolol and ivabradine ... carvedilol and ivabradine …
Matched Products: … CORALAN 5MG FILM-COATED TABLETS ... CORALAN 7.5MG FILM-COATED TABLETS ... IVASWIFT FILM-COATED TABLET 5MG …

2,3,6A,7,8,9-HEXAHYDRO-11H-[1,4]DIOXINO[2,3-G]PYRROLO[2,1-B][1,3]BENZOXAZIN-11-ONE

Experimental
Matched Name: … 2,3,6A,7,8,9-HEXAHYDRO-11H-[1,4]DIOXINO[2,3-G]PYRROLO[2,1-B][1,3]BENZOXAZIN-11-ONE …

Cilazapril

Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. It belongs to the angiotensin-converting enzyme inhibitors (ACE inhibitors) class of drugs. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. It is branded as Inhibace in Canada and...
Approved
Matched Description: … It is branded as Inhibace in Canada and other countries, Vascace and Dynorm in a number of European countries ... Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. …
Matched Mixtures name: … ACEPRIX PLUS 5 MG/12.5 MG FILM TABLET, 30 ADET ... İNHİBACE PLUS 5 MG/12,5 MG FILM KAPLI TABLET, 28 ADET …
Matched Categories: … ACE Inhibitors and Diuretics ... cilazapril and diuretics …
Matched Products: … ACEPRIX 1 MG FILM TABLET, 30 ADET ... ACEPRIX 5 MG FILM TABLET, 30 ADET ... ACEPRIX 2.5 MG FILM TABLET, 30 ADET …

Teriflunomide

Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. It is marketed under the name Aubagio® and is indicated for the treatment of multiple sclerosis, specifically relapsing forms. The FDA label states an important warning about the risk of hepatoxicity and...
Approved
Matched Description: … Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting ... It is marketed under the name Aubagio® and is indicated for the treatment of multiple sclerosis, specifically ... The FDA label states an important warning about the risk of hepatoxicity and teratogenicity for patients …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Leflunomide and metabolite …
Matched Products: … Mar-teriflunomide ... AUBAGIO FILM-COATED TABLETS 14mg ... AUBAGIO 14mg Film-coated Tablets …

Alogliptin

Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4). Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. FDA approved January 25, 2013.
Approved
Matched Description: … Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (> …
Matched Mixtures name: … Alogliptin and Metformin Hydrochloride ... Alogliptin and Pioglitazone ... Alogliptin and Metformin Hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and alogliptin ... pioglitazone and alogliptin ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Nesina 25mg Film-Coated Tablet ... Nesina 6.25mg Film-Coated Tablet ... Nesina 12.5mg Film-Coated Tablet …

Ursodeoxycholic acid

Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool.[A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional medicine dates back more than a hundred years.[A256267,A256463] UDCA was first characterized...
Approved
Investigational
Matched Description: … [A256267,A256463] UDCA was first characterized in the bile of the Chinese black bear and is formed by ... [A256272] UDCA was first approved by the FDA in 1987 for dissolution of gallstones and for primary …
Matched Categories: … Alimentary Tract and Metabolism ... Bile acids and derivatives ... Bile Acids and Salts ... Bile and Liver Therapy ... Cholagogues and Choleretics …
Matched Products: … URSOKOL 250 MG FILM TABLET,100 ADET ... URSOKOL 500 MG FILM TABLET,100 ADET ... URSOKOL 750 MG FİLM TABLET, 50 ADET …

Famciclovir

Famciclovir, marketed as Famvir by Novartis, is a guanine analogue used to treat herpes virus infections. It is most commonly used to treat herpes zoster (shingles). Famciclovir is a prodrug of penciclovir with higher oral bioavailability.
Approved
Investigational
Matched Categories: … Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … FAMVIR 250 MG FILM TABLET, 21 ADET ... VIRMOL 125 MG FILM KAPLI TABLET, 14 ADET ... VIRMOL 500 MG FILM KAPLI TABLET, 14 ADET …

Dexibuprofen

Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID). It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties. It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen due to higher concentration of active S enantiomer. Dexibuprofen has a...
Approved
Investigational
Matched Description: … the racemic ibuprofen and displays improved oral bioavilability [A19259]. ... It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen ... Dexibuprofen has a slower dissolution rate in the simulated gastric and enteric juices compared with …
Matched Categories: … Ibuprofen and isomer ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … IBUDEX 400 FILM TABLET, 10 ADET ... IBUDEX 400 FILM TABLET, 30 ADET ... IBUDEX 400 MG FILM TABLET, 20 ADET …

Frovatriptan

Frovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head.
Approved
Investigational
Matched Description: … Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head. …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … MIGREX 2.5 MG FILM TABLET, 12 ADET ... MIGREX 2.5 MG FILM TABLET, 3 ADET ... MIGREX 2.5 MG FILM TABLET, 6 ADET …

Clarithromycin

Clarithromycin, a semisynthetic macrolide antibiotic derived from erythromycin, inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the translation and protein assembly process. Clarithromycin may be bacteriostatic or bactericidal depending on the organism and drug...
Approved
Matched Description: … translation and protein assembly process. ... Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the ... Clarithromycin may be bacteriostatic or bactericidal depending on the organism and drug concentration …
Matched Mixtures name: … Lansoprazole, Amoxicillin, and Clarithromycin ... Lansoprazole, Amoxicillin and Clarithromycin ... Lansoprazole, Amoxicillin and Clarithromycin …
Matched Categories: … Alimentary Tract and Metabolism ... Erythromycin and similars ... Macrolides, Lincosamides and Streptogramins ... Metabolic Side Effects of Drugs and Substances ... vonoprazan, amoxicillin and clarithromycin …
Matched Products: … KLAMER 250MG FILM TABLET ... BICROLID FILM-COATED CAPLET 250 mg ... Clarem Film-Coated Tablet 500 mg …

Eletriptan

Eletriptan is a second generation triptan drug developed by Pfizer Inc for the treatment of migraine headaches.
Approved
Investigational
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … RELPAX 40 MG FILM TABLET, 2 ADET ... RELPAX 40 MG FILM TABLET, 4 ADET ... RELPAX 40 MG FILM TABLET, 1 ADET …

Moclobemide

A reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder. Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (TCA) or selective serotonin reuptake inhibitors (SSRIs)....
Approved
Investigational
Matched Description: … Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide ... is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (TCA ... Due to negligible anticholinergic and antihistaminic actions, moclobemide has been better tolerated than …
Matched Categories: … Benzamides and benzamide derivatives …
Matched Products: … Aurorix Film Coated Tablet 150mg ... Aurorix Film Coated Tablet 300mg ... AURORIX 150 MG FILM KAPLI TABLET, 30 ADET …

Cobimetinib

Cobimetinib is an orally active, potent and highly selective small molecule inhibiting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), and central components of the RAS/RAF/MEK/ERK signal transduction pathway. It has been approved in Switzerland and the US, in combination with vemurafenib for the treatment of patients with unresectable or...
Approved
Investigational
Matched Description: … Cobimetinib is an orally active, potent and highly selective small molecule inhibiting mitogen-activated ... protein kinase kinase 1 (MAP2K1 or MEK1), and central components of the RAS/RAF/MEK/ERK signal transduction ... It has been approved in Switzerland and the US, in combination with vemurafenib for the treatment of …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … COTELLIC 20 MG FILM KAPLI TABLET,63 FILM KAPLI TABLET ... COTELLIC FILM COATED TABLET 20MG ... COTELLIC FILM-COATED TABLET 20 MG …

Sorafenib

Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis. First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular carcinoma, sorafenib is also...
Approved
Investigational
Matched Description: … Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. ... in tumour cell proliferation and tumour angiogenesis. ... It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … NEXAVAR FILM-COATED TABLETS 200 MG ... NEXAVAR 200 MG FILM KAPLI TABLET, 112 ADET ... inFENIB (Sorafenib 200mg) Film Coated Tablet …

Verapamil

Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs...
Approved
Matched Description: … heart arrhythmias, and angina,[L8791] and was the first calcium channel antagonist to be introduced ... drugs like [diltiazem] and [flunarizine], but is chemically unrelated to other cardioactive medications ... [L8791] Verapamil is administered as a racemic mixture containing equal amounts of the S- and R-enantiomer …
Matched Mixtures name: … TARKA 180/2 FILM TABLET, 28 ADET ... TARKA FORTE 240/4 FILM TABLET, 28 ADET ... VERAPIN 180 MG/2 MG FILM TABLET, 28 ADET …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Verapamil and analogues ... trandolapril and verapamil ... Calcium Channel Blockers ... Calcium Channel Blockers (Nondihydropyridine) …
Matched Products: … VERA PRESS 120 MG. ... VERAPAMIL HENNIG 120MG FIL ... VERAPAMIL HENNIG 40MG FILM …

Moxonidine

Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive. As well, moxonidine has been shown...
Approved
Investigational
Matched Description: … suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and ... calcium channel blockers are not appropriate or irresponsive. …
Matched Categories: … moxonidine and diuretics …
Matched Products: … MOXONIDIN - CT 0.2MG FILM ... MOXONIDIN - CT 0.3MG FILM ... MOXONIDIN - CT 0.4MG FILM …

Abrocitinib

Abrocitinib is an oral small-molecule inhibitor of Janus kinase 1 (JAK1). Janus kinases are intracellular enzymes involved in transduction pathways that regulate hematopoiesis and immune cell function. The Janus kinase (JAK)–signal transducer and activator of transcription (STAT) signalling pathway plays a central role in the pathogenesis of a variety of...
Approved
Investigational
Matched Description: … 2022, the FDA approved abrocitinib for the treatment of refractory, moderate-to-severe AD in adults whose ... Commission on December 10, 2021, for the treatment of moderate-to-severe atopic dermatitis (AD) in adults who ... Janus kinases are intracellular enzymes involved in transduction pathways that regulate hematopoiesis and …
Matched Products: … CİBİNQO 50 MG FİLM KAPLI TABLET, 28 ADET ... CİBİNQO 200 MG FİLM KAPLI TABLET, 28 ADET ... CİBİNQO 100 MG FİLM KAPLI TABLET, 28 ADET …

Benzyl N-[(2S)-5-(diaminomethylamino)-1-[[(2S)-4-fluoro-3-oxobutan-2-yl]amino]-1-oxopentan-2-yl]carbamate

Experimental
Matched Name: … Benzyl N-[(2S)-5-(diaminomethylamino)-1-[[(2S)-4-fluoro-3-oxobutan-2-yl]amino]-1-oxopentan-2-yl]carbamate …
Matched Iupac: … benzyl N-[(1S)-4-[(diaminomethyl)amino]-1-{[(2S)-4-fluoro-3-oxobutan-2-yl]carbamoyl}butyl]carbamate …

Ramelteon

Ramelteon is the first in a new class of sleep agents that selectively binds to the melatonin receptors in the suprachiasmatic nucleus (SCN). It is used for insomnia, particularly delayed sleep onset. Ramelteon has not been shown to produce dependence and has shown no potential for abuse.
Approved
Investigational
Matched Description: … Ramelteon has not been shown to produce dependence and has shown no potential for abuse. …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … RAMELDA 8 MG FILM KAPLI TABLET,30 ADET ... RAMELDA 8 MG FILM KAPLI TABLET,10 ADET ... ROZEREST 8 MG FİLM KAPLI TABLET, 10 ADET …

Metoprolol

Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.[A175159, L5530] The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. To this date,...
Approved
Investigational
Matched Description: … Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives ... widely prescribed in the Netherlands, New Zealand, and the US. ... [T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is …
Matched Mixtures name: … IMPLICOR FILM-COATED TABLET 25 mg/5 mg ... IMPLICOR FILM-COATED TABLET 50 mg/5 mg ... IMPLICOR 50MG/5MG FILM-COATED TABLETS …
Matched Categories: … Beta blocking agents and calcium channel blockers ... Beta Blocking Agents and Thiazides ... metoprolol and felodipine ... Beta Blocking Agents, Selective, and Thiazides ... metoprolol and ivabradine …
Matched Products: … Metoprolol Tartrate film coated ... PROBLOK 100 MG FİLM TABLET, 20 ADET ... LOPRESOR 100 MG FILM TABLET, 20 ADET …

Varenicline

Varenicline is a prescription medication used to treat smoking addiction. This medication is the first approved nicotinic receptor partial agonist. Specifically, varenicline is a partial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine receptor. In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A full...
Approved
Investigational
Matched Description: … Chantix, has been associated with seizures and that some patients who drink while taking the drug may ... On March 9, 2015, the U.S. ... In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. …
Matched Mixtures name: … CHAMPIX 0,5 MG 11 + 1 MG 42 FILM KAPLI TABLET ... CHAMPIX 0,5 MG 11 + 1 MG 42 FILM KAPLI TABLET ... CHAMPIX 0,5 MG 1 MG FILM KAPLI TABLET, 11 VE 14 ADET …
Matched Products: … CHAMPIX 0.5MG FILM-COATED TABLETS ... CHAMPIX 1.0MG FILM-COATED TABLETS ... CHAMPIX 1 MG FILM KAPLI TABLET, 28 ADET …

Quinidine

Quinidine is a D-isomer of quinine present in the bark of the Cinchona tree and similar plant species. This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.[A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute...
Approved
Investigational
Matched Synonyms: … CIN-QUIN …
Matched Description: … Quinidine is a D-isomer of [quinine] present in the bark of the Cinchona tree and similar plant species ... This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication. ... [A38016] It prolongs cellular action potential by blocking sodium and potassium currents. …
Matched Categories: … Quinine and stereoisomer ... Metabolic Side Effects of Drugs and Substances …

Tamoxifen

Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations.[A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments.[L7799,L7802] Tamoxifen may no longer be the preferred treatment for these types of cancers...
Approved
Matched Description: … treatment for these types of cancers as patients generally have better survival, side effect profiles, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … NOLVADEX 10 MG FILM TABLET, 30 ADET ... NOLVADEX 10 MG FILM TABLET, 250 ADET ... TAMOXIT 20 MG FİLM KAPLI TABLET (TAMOFEN), 100 TABLET …
Displaying drugs 1126 - 1150 of 1322 in total