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Displaying drugs 11526 - 11550 of 12768 in total
Avagacestat has been investigated for the basic science and treatment of Alzheimer Disease.
Investigational
Matched Iupac: … (2R)-5,5,5-trifluoro-2-(N-{[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl}4-chlorobenzenesulfonamido …
Atreleuton has been used in trials studying the treatment of Atherosclerosis and Coronary Artery Disease.
Investigational
Matched Iupac: … 1-[(2R)-4-{5-[(4-fluorophenyl)methyl]thiophen-2-yl}but-3-yn-2-yl]-1-hydroxyurea …
Experimental
Matched Iupac: … 2-[2,5-bis(aziridin-1-yl)-4-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl]-2-methoxyethyl carbamate …
Experimental
Matched Iupac: … 5-[(morpholin-4-yl)methyl]-3-[(E)-[(5-nitrofuran-2-yl)methylidene]amino]-1,3-oxazolidin-2-one …
Experimental
Matched Iupac: … [(2R)-4-[(2-{3-[(2R)-4-[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2 ... ]-2-hydroxy-4-oxobutyl]trimethylazanium ... -yl]methoxy}(hydroxy)phosphoryl phosphonato)oxy]-2-hydroxy-3,3-dimethylbutanamido]propanamido}ethyl)sulfanyl …
Basifungin, also known as aureuobacidin A, is a phosphorylceramide synthase inhibitor , .
Experimental
Matched Iupac: … (3R,6S,9S,12S,15S,21S,24S,29aS)-21,24-dibenzyl-15-[(2R)-butan-2-yl]-5,11,23-trimethyl-3-[(2R)-3-methylbutan ... -2-yl]-9-(2-methylpropyl)-6,12,18-tris(propan-2-yl)-octacosahydropyrrolo[1,2-m]1-oxa-4,7,10,13,16,19,22,25 …
Experimental
Matched Iupac: … (2S,3R,4S,5S,6R)-2-[amino(hydroxy)methyl]-2-azido-6-(hydroxymethyl)oxane-3,4,5-triol …
UC-781 is a thiocarboxanilide non-nucleoside reverse transcriptase inhibitor (NNRTI). It is a topical microbicide targeted against the AIDS virus.
Investigational
Matched Iupac: … N-{4-chloro-3-[(3-methylbut-2-en-1-yl)oxy]phenyl}-2-methylfuran-3-carbothioamide …
Investigational
Matched Iupac: … N-(2-amino-4-fluorophenyl)-4-{[(2E)-3-(pyridin-3-yl)prop-2-enamido]methyl}benzamide …
PF-04958242 has been used in trials studying the basic science and treatment of Schizophrenia and Hearing Loss, Sensorineural.
Investigational
Matched Iupac: … N-[(3S,4S)-4-[4-(5-cyanothiophen-2-yl)phenoxy]oxolan-3-yl]propane-2-sulfonamide …
Elubrixin has been used in trials studying the treatment of Cystic Fibrosis, Colitis, Ulcerative, and Chronic Obstructive Pulmonary Disease (COPD).
Investigational
Matched Iupac: … 1-[4-chloro-2-hydroxy-3-(piperazine-1-sulfonyl)phenyl]-3-(2-chloro-3-fluorophenyl)urea …
Begacestat has been used in trials studying the treatment and basic science of Alzheimer Disease.
Investigational
Matched Iupac: … 5-chloro-N-[(2S)-4,4,4-trifluoro-1-hydroxy-3-(trifluoromethyl)butan-2-yl]thiophene-2-sulfonamide …
Elsulfavirine is under investigation in clinical trial NCT03706898 (Study to Evaluate the Safety and PK of Elpida® in Healthy Subjects and Patients With Hepatic Impairment and to Assess the Impact of Food Intake and Drug-Drug Interactions With Other Antiviral Drugs).
Investigational
Matched Iupac: … N-(4-{2-[4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluorophenyl]acetamido}-3-chlorobenzenesulfonyl)propanamide …
Investigational
Matched Iupac: … (4S)-4-[(2S)-2-aminopropanamido]-4-{[(1S)-2-carboxy-1-[(carboxymethyl)carbamoyl]ethyl]carbamoyl}butanoic …
Tipranavir C-14 is under investigation in clinical trial NCT02253797 (Pharmacokinetics of Tipranavir/Ritonavir and Its Metabolites in Healthy Male Subjects).
Investigational
Matched Iupac: … N-{3-[(1R)-1-[(6R)-4-hydroxy-2-oxo-6-(2-phenylethyl)-6-propyl-5,6-dihydro-2H-pyran-3-yl](1-14C)propyl ... ]phenyl}-5-(trifluoromethyl)pyridine-2-sulfonamide …
A synthetic, cell permeable peptide that blocks the MAPK-JNK signal pathway; has potential therapeutic value for long-term protection of both the morphological integrity and physiological function of the organ of Corti during times of oxidative stress.
Investigational
Matched Iupac: … (3R)-3-amino-3-{[(1R)-1-{[(1R)-1-{[(2R)-1-[(2R)-2-{[(1R)-1-{[(2R)-1-[(2R)-2-{[(1R)-1-{[(1R)-1-{[(1R)- ... ]carbamoyl}-4-carbamimidamidobutyl]carbamoyl}-3-carbamoylpropyl]carbamoyl}-4-carbamimidamidobutyl]carbamoyl ... ]carbamoyl}pyrrolidin-1-yl]-3-hydroxy-1-oxobutan-2-yl]carbamoyl}-2-hydroxypropyl]carbamoyl}-3-methylbutyl ... -1-oxopentan-2-yl]carbamoyl}-2-hydroxyethyl]carbamoyl}-3-carbamoylpropyl]carbamoyl}propanoic acid ... ]carbamoyl}-2-carbamoylethyl]carbamoyl}-3-methylbutyl]carbamoyl}-2-phenylethyl]carbamoyl}pyrrolidin-1 …
Experimental
Matched Iupac: … (2S)-2-({[(S)-(2-imino-1,3-diazinan-4-yl)({[(1S)-3-methyl-1-{[(2S)-1-oxo-3-phenylpropan-2-yl]carbamoyl ... }butyl]carbamoyl})methyl]carbamoyl}amino)-3-phenylpropanoic acid …
Filibuvir has been used in trials studying the treatment of Hepatitis, Hepatitis C, and Chronic Hepatitis C.
Investigational
Matched Iupac: … (6R)-6-cyclopentyl-6-[2-(2,6-diethylpyridin-4-yl)ethyl]-3-({5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin ... -2-yl}methyl)-4-hydroxy-5,6-dihydro-2H-pyran-2-one …
GSK690693 has been used in trials studying the treatment of Tumor, CANCER, and Lymphoma.
Investigational
Matched Iupac: … -4-yl]-2-methylbut-3-yn-2-ol ... 4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-piperidin-3-yl]methoxy}-1H-imidazo[4,5-c]pyridin …
Lapaquistat is under investigation in clinical trial NCT00256178 (Efficacy of Lapaquistat Acetate and Simvastatin in Subjects With Primary Dyslipidemia.).
Investigational
Matched Iupac: … -4,1-benzoxazepin-3-yl]acetyl}piperidin-4-yl)acetic acid ... 2-(1-{2-[(3R,5S)-7-chloro-5-(2,3-dimethoxyphenyl)-1-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-1,2,3,5-tetrahydro …
Experimental
Matched Iupac: … 3-(4-carbamimidoylphenyl)-2-oxopropanoic acid …
Experimental
Matched Iupac: … (2S)-5-(carbamoylamino)-2-acetamidopentanoic acid …
Experimental
Matched Iupac: … (3S,4S)-1,3,4,5-tetrahydroxypentan-2-one …
Experimental
Matched Iupac: … (2S)-2-(carbamoylamino)-3-phenylpropanoic acid …
Palifosfamide (ZIO-201) is a proprietary stabilized metabolite of ifosfamide. Ifosfamide has been shown to be effective in high doses in treating testicular cancer, sarcoma and lymphoma.
Investigational
Matched Iupac: … bis[(2-chloroethyl)amino]phosphinic acid …
Displaying drugs 11526 - 11550 of 12768 in total