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Displaying drugs 11726 - 11750 of 13062 in total
Sulfatide
Any of a class of cerebroside sulfuric esters, they are found largely in the medullated nerve fibers and may accumulate in metachromatic leukodystrophy.
Experimental
Matched Synonyms: … 2-hydroxytetracosanoyl sulfatide ... 2-hydroxytetracosanoylgalactosylceramide sulfate …
Matched Iupac: … [(2R,3R,4S,5S,6R)-3,5-dihydroxy-2-{[(2S,3R,4E)-3-hydroxy-2-[(2R)-2-hydroxytetracosanamido]octadec-4-en ... -1-yl]oxy}-6-(hydroxymethyl)oxan-4-yl]oxidanesulfonic acid …
Matched Iupac: … [(2R,3R,4S,5S,6R)-3,5-dihydroxy-2-{[(2S,3R,4E)-3-hydroxy-2-[(2R)-2-hydroxytetracosanamido]octadec-4-en ... -1-yl]oxy}-6-(hydroxymethyl)oxan-4-yl]oxidanesulfonic acid …
Ginsenoside C
Nutraceutical
Matched Iupac: … 5-yl]oxy}-6-(hydroxymethyl)oxan-3-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol ... -trihydroxyoxan-2-yl]oxy}methyl)oxan-2-yl]oxy}hept-5-en-2-yl]tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan- ... (2S,3R,4S,5S,6R)-2-{[(2R,3R,4S,5S,6R)-4,5-dihydroxy-2-{[(1R,2R,5S,7R,10R,11R,14S,15R,16R)-16-hydroxy- ... 2,6,6,10,11-pentamethyl-14-[(2S)-6-methyl-2-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2S,3R,4S,5S)-3,4,5 …
Rotigaptide
Rotigaptide is under investigation for the basic science of Heart Disease and Vascular Disease.
Investigational
Matched Iupac: … (2R)-N-(carbamoylmethyl)-2-(2-{[(2R,4S)-1-[(2R)-1-[(2R)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]pyrrolidine ... -2-carbonyl]-4-hydroxypyrrolidin-2-yl]formamido}acetamido)propanamide …
Farletuzumab ecteribulin
Farletuzumab ecteribulin is under investigation in clinical trial NCT04300556 (A Study to Evaluate the Safety, Tolerability, and Efficacy of Morab-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (Frα)-targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types).
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Isobutyramide
Investigational
Matched Synonyms: … 2-methylpropionamide …
Matched Iupac: … 2-methylpropanamide …
Matched Iupac: … 2-methylpropanamide …
L-Cycloserine
Investigational
Matched Synonyms: … (s)-4-amino-3-isoxazolidinone …
Matched Iupac: … (4S)-4-amino-1,2-oxazolidin-3-one …
Matched Iupac: … (4S)-4-amino-1,2-oxazolidin-3-one …
Ecromeximab
Ecromeximab has been used in trials studying the treatment of Cutaneous Melanoma and Metastatic Melanoma.
Investigational
Omipalisib
Omipalisib has been used in trials studying the treatment of CANCER, Solid Tumours, and Idiopathic Pulmonary Fibrosis.
Investigational
Matched Iupac: … 2,4-difluoro-N-{2-methoxy-5-[4-(pyridazin-4-yl)quinolin-6-yl]pyridin-3-yl}benzene-1-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
Hydroxypropyl betadex
Hydroxypropyl betadex is under investigation in clinical trial NCT03471143 (Study of IV VTS-270 for Infantile Liver Disease Associated With Niemann-Pick Disease, Type C).
Investigational
Matched Synonyms: … 2-Hydroxypropyl-b-cyclodextrin ... 2-Hydroxylpropyl-beta-cyclodextrin ... 2-HYDROXYPROPYL-BETA-CYCLODEXTRIN …
Matched Iupac: … [31.2.2.2^{3,6}.2^{8,11}.2^{13,16}.2^{18,21}.2^{23,26}.2^{28,31}]nonatetracontane-36,37,38,39,41,42,43,45,46,48 ... 36R,37R,38R,39R,40R,41R,42R,43R,45R,46S,47R,48S,49R)-5,10,25,35-tetrakis(hydroxymethyl)-40,47,49-tris(2- ... hydroxypropoxy)-15,20,30-tris[(2-hydroxypropoxy)methyl]-2,4,7,9,12,14,17,19,22,24,27,29,32,34-tetradecaoxaoctacyclo …
Matched Iupac: … [31.2.2.2^{3,6}.2^{8,11}.2^{13,16}.2^{18,21}.2^{23,26}.2^{28,31}]nonatetracontane-36,37,38,39,41,42,43,45,46,48 ... 36R,37R,38R,39R,40R,41R,42R,43R,45R,46S,47R,48S,49R)-5,10,25,35-tetrakis(hydroxymethyl)-40,47,49-tris(2- ... hydroxypropoxy)-15,20,30-tris[(2-hydroxypropoxy)methyl]-2,4,7,9,12,14,17,19,22,24,27,29,32,34-tetradecaoxaoctacyclo …
Quisqualic acid
Quisqualic acid is an agonist at two subsets of excitatory amino acid receptors, ionotropic receptors that directly control membrane channels and metabotropic receptors that indirectly mediate calcium mobilization from intracellular stores. The compound is obtained from the seeds and fruit of Quisqualis chinensis.
Experimental
Matched Iupac: … (2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Iclaprim
Investigational
Matched Iupac: … 5-[(2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)methyl]pyrimidine-2,4-diamine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Buflomedil
Experimental
Matched Iupac: … 4-(pyrrolidin-1-yl)-1-(2,4,6-trimethoxyphenyl)butan-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Zolimidine
Experimental
Matched Iupac: … 2-(4-methanesulfonylphenyl)imidazo[1,2-a]pyridine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Clopamide
Clopamide is an oral diuretic agent with antihypertensive activity. Like thiazide diuretics, it has an aromatic sulfonamide base but with no double-ring structure.
Experimental
Matched Iupac: … 4-chloro-N-[(2R,6S)-2,6-dimethylpiperidin-1-yl]-3-sulfamoylbenzamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Relcovaptan
Investigational
Matched Iupac: … (2S)-1-[(2R,3S)-5-chloro-3-(2-chlorophenyl)-1-(3,4-dimethoxybenzenesulfonyl)-3-hydroxy-2,3-dihydro-1H-indole ... -2-carbonyl]pyrrolidine-2-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Abivertinib
Abivertinib is a tyrosine kinase inhibitor targeted against mutant forms of both human epidermal growth factor receptor (EGFR) and Bruton's tyrosine kinase (BTK). It has been investigated for use in the treatment of non-small cell lung cancer (NSCLC) and B-cell malignancies. In binding to and inhibiting EGFR and BTK receptors,...
Investigational
Matched Iupac: … N-{3-[(2-{[3-fluoro-4-(4-methylpiperazin-1-yl)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]phenyl ... }prop-2-enamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Cilazaprilat
Experimental
Matched Iupac: … (1S,9S)-9-{[(1S)-1-carboxy-3-phenylpropyl]amino}-10-oxo-octahydro-1H-pyridazino[1,2-a][1,2]diazepine- ... 1-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Patulin
Experimental
Matched Iupac: … 4-hydroxy-2H,4H,6H-furo[3,2-c]pyran-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Merestinib
Merestinib has been used in trials studying the treatment of Cancer, Solid Tumor, Advanced cancer, ColoRectal Cancer, and Metastatic Cancer, among others.
Investigational
Matched Iupac: … N-(3-fluoro-4-{[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxy}phenyl)-1-(4-fluorophenyl)-6-methyl- ... 2-oxo-1,2-dihydropyridine-3-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Benzylthiouracil
Experimental
Matched Iupac: … 6-benzyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
N4-Hydroxycytidine
N4-Hydroxyctidine, or EIDD-1931, is a ribonucleoside analog which induces mutations in RNA virions.[A193008,A193011] N4-hydroxycytidine was first described in the literature in 1980 as a potent mutagen of bacteria and phage. It has shown antiviral activity against Venezuelan equine encephalitis virus, and the human coronavirus HCoV-NL63 in vitro. N4-hydroxycytodine has been...
Experimental
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)-1,2-dihydropyrimidin-2- …
Matched Description: … [A193014] It is orally bioavailable in mice and distributes into tissue before becoming the active 5’ ... [A193017] N4-hydroxycytodine has been shown to inhibit SARS-CoV-2 as well as other human and bat coronaviruses …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … [A193014] It is orally bioavailable in mice and distributes into tissue before becoming the active 5’ ... [A193017] N4-hydroxycytodine has been shown to inhibit SARS-CoV-2 as well as other human and bat coronaviruses …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Pitofenone
Experimental
Matched Iupac: … methyl 2-{4-[2-(piperidin-1-yl)ethoxy]benzoyl}benzoate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Tralesinidase alfa
Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. It is being investigated for the treatment of mucopolysaccharidosis type IIIB (MPS IIIB), also known as Sanfilippo syndrome B.
Investigational
Matched Synonyms: … Alpha-N-acetyglucosaminidase-insulin-like-growth-factor-2 fusion protein ... Recombinant human alpha-N-acetylglucosaminidase-insulin-like growth factor-2 …
Matched Description: … fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. …
Matched Description: … fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. …
Displaying drugs 11726 - 11750 of 13062 in total